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| 1 | Multispectral sensing of biological liquids with hollow-core microstructured optical fibres显示文摘The state of the art in optical biosensing is focused on reaching high sensitivity at a single wavelength by using any type of optical resonance.This common strategy,however,disregards the promising possibility of simultaneous measurements of a bioanalyte’s refractive index over a broadband spectral domain.Here,we address this issue by introducing the approach of in-fibre multispectral optical sensing(IMOS).The operating principle relies on detecting changes in the transmission of a hollow-core microstructured optical fibre when a bioanalyte is streamed through it via liquid cells.IMOS offers a unique opportunity to measure the refractive index at 42 wavelengths,with a sensitivity up to ~3000 nm per refractive index unit(RIU)and a figure of merit reaching 99 RIU^(−1) in the visible and near-infra-red spectral ranges.We apply this technique to determine the concentration and refractive index dispersion for bovine serum albumin and show that the accuracy meets clinical needs. | Timur Ermatov Roman E.Noskov Andrey AMachnev Ivan Gnusov Vsevolod Atkin Ekaterina N.Lazareva Sergei V.German Sergey S.Kosolobov Timofei S.Zatsepin Olga V.Sergeeva Julia S.Skibina Pavel Ginzburg Valery V.Tuchin Pavlos G.Lagoudakis Dmitry A.Gorin | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 2 | Advances in the development of new biomarkers for Alzheimer’s disease显示文摘Alzheimer’s disease(AD)is a complex,heterogeneous,progressive disease and is the most common type of neurodegenerative dementia.The prevalence of AD is expected to increase as the population ages,placing an additional burden on national healthcare systems.There is a large need for new diagnostic tests that can detect AD at an early stage with high specificity at relatively low cost.The development of modern analytical diagnostic tools has made it possible to determine several biomarkers of AD with high specificity,including pathogenic proteins,markers of synaptic dysfunction,and markers of inflammation in the blood.There is a considerable potential in using microRNA(miRNA)as markers of AD,and diagnostic studies based on miRNA panels suggest that AD could potentially be determined with high accuracy for individual patients.Studies of the retina with improved methods of visualization of the fundus are also showing promising results for the potential diagnosis of the disease.This review focuses on the recent developments of blood,plasma,and ocular biomarkers for the diagnosis of AD. | Timofey O.Klyucherev Pawel Olszewski Alena A.Shalimova Vladimir N.Chubarev Vadim V.Tarasov Misty M.Attwood Stina Syvänen Helgi B.Schiöth | 2022 | Translational Neurodegeneration2022，11，1： | 2 |
| 3 | Thermal analysis of novel underfill materials with optimum processing characteristics 显示文摘 | Yang Liu Yi-Feng Wang Timofey G Gerasimov | 2005 | Journal of Applied Polymer Science2005，98，： | 1 |
| 4 | Heterogeneity and degree of TIMP4, GATA4, SOX18, and EGFL7 gene promoter methylation in non–small cell lung cancer and surrounding tissues显示文摘 | Tatyana Azhikina Alena Kozlova Timofey Skvortsov Eugene Sverdlov | 2011 | Cancer Genetics2011，，9： | 1 |
| 5 | On BC1 RNA and the fragile X mental retardation protein显示文摘 | Anna Iacoangeli Timofey S Rozhdestvensky | 2008 | PNAS2008，105，2： | 1 |
| 6 | Phase equilibria and eutectic growth in ternary organic system camphor-neopentylglycol-succinonitrile显示文摘 | Victor Timofey Witusiewicz Ulrike Hecht Laszlo Sturz Stephan Rex | 2006 | Journal of Crystal Growth2006，286，： | 1 |
| 7 | Thermal analysis of novel underfill materials with optimum processing characteristics 显示文摘 | Yang Liu Yi-Feng Wang Timofey G Gerasimov | 2005 | Journal of Applied Polymer Science2005，98，： | 1 |
| 8 | Phase equilibria and eutectic growth in ternary organic system (D) camphor-neopentylglycol-succinonitrile显示文摘 | WITUSIEWICZ Victor Timofey HECHT Ulrike STURZ Laszlo | | 0，，11： | 1 |
| 9 | Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease显示文摘 | Giuseppa Mudò Johanna M?kel? Valentina Di Liberto Timofey V. Tselykh Melania Olivieri Petteri Piepponen Ove Eriksson Annika M?lki? Alessandra Bonomo Minna Kairisalo Jose A. Aguirre Laura Korhonen Natale Belluardo Dan Lindholm | 2012 | Cellular and Molecular Life Sciences2012，，7： | 1 |
| 10 | Thermal analysis of novel underfill materials with optimum processing characteristics显示文摘 | Yang Liu Yi-Feng Wang Timofey G Gerasimov | 2005 | Journal of Applied Polymer Science2005，98，： | 1 |
| 11 | Correlation of aerobic biodegradability of sulfonated azo dyes with the chemical structure 显示文摘 | SUZUKI T TIMOFEI S Kurunczi L | 2001 | Chemosphere2001，45，1： | 1 |
| 12 | Correlation of aerobic biodegradability of sulfonated azo dyes with the chemical structure 显示文摘 | Suzuki T Timofei S Kurunczi L | 2001 | Chemosphere2001，45，1： | 1 |
| 13 | Thermal analysis of novel underfill materials with optimum processing characteristics显示文摘 | Liu Yang Wang Yi-Feng Timofey G Gerasimov | 2005 | Journal of Applied Polymer Science2005，98，： | 1 |
| 14 | Quantitative structure-enantioselective retention relationships for chromatographic separation of arylalkylcarbinols on Pirkle type chiral stationary phases显示文摘 | Suzuki T Timofei S Iuoras B E | 2001 | J Chromatogr A2001，922，： | 1 |
| 15 | Modeling antiphase boundary energies of Ni_(3)Al-based alloys using automated density functional theory and machine learning显示文摘Antiphase boundaries(APBs)are planar defects that play a critical role in strengthening Ni-based superalloys,and their sensitivity to alloy composition offers a flexible tuning parameter for alloy design.Here,we report a computational workflow to enable the development of sufficient data to train machine-learning(ML)models to automate the study of the effect of composition on the(111)APB energy in Ni_(3)Al-based alloys.We employ ML to leverage this wealth of data and identify several physical properties that are used to build predictive models for the APB energy that achieve a cross-validation error of 0.033 J m^(−2).We demonstrate the transferability of these models by predicting APB energies in commercial superalloys.Moreover,our use of physically motivated features such as the ordering energy and stoichiometry-based features opens the way to using existing materials properties databases to guide superalloy design strategies to maximize the APB energy. | Enze Chen Artur Tamm Tao Wang Mario E.Epler Mark Asta Timofey Frolov | 2022 | npj Computational Materials2022，，1： | 0 |
| 16 | Antitumor efficacy of multi-target in situ vaccinations with CpG oligodeoxynucleotides,anti-OX40,anti-PD1 antibodies,and aptamers显示文摘To overcome immune tolerance to cancer,the immune system needs to be exposed to a multi-target action intervention.Here,we investigated the activating effect of CpG oligodeoxynucleotides(ODNs),mesyl phosphoramidate CpG ODNs,anti-OX40 antibodies,and OX40 RNA aptamers on major populations of immunocompetent cells ex vivo.Comparative analysis of the antitumor effects of in situ vaccination with CpG ODNs and anti-OX40 antibodies,as well as several other combinations,such as mesyl phosphoramidate CpG ODNs and OX40 RNA aptamers,was conducted.Antibodies against programmed death 1(PD1)checkpoint inhibitors or their corresponding PD1 DNA aptamers were also added to vaccination regimens for analytical purposes.Four scenarios were considered:a weakly immunogenic Krebs-2 carcinoma grafted in CBA mice;a moderately immunogenic Lewis carcinoma grafted in C57Black/6 mice;and an immunogenic A20 B cell lymphoma or an Ehrlich carcinoma grafted in BALB/c mice.Adding anti-PD1 antibodies(CpG+αOX40+αPD1)to in situ vaccinations boosts the antitumor effect.When to be used instead of antibodies,aptamers also possess antitumor activity,although this effect was less pronounced.The strongest effect across all the tumors was observed in highly immunogenic A20 B cell lymphoma and Ehrlich carcinoma. | Anastasia S.Proskurina Vera S.Ruzanova Genrikh S.Ritter Yaroslav R.Efremov Zakhar S.Mustafin Sergey A.Lashin Ekaterina A.Burakova Alesya A.Fokina Timofei S.Zatsepin Dmitry A.Stetsenko Olga Y.Leplina Alexandr A.Ostanin Elena R.Chernykh Sergey S.Bogachev | 2023 | The Journal of Biomedical Research2023，37，3： | 0 |
| 17 | 我留在中国的理由显示文摘我与中国的关联由来已久,我的父母是20世纪90年代与中国科学和教育领域建立联系的苏联专家之一。就在我10岁生日前夕,母亲被政府派往武汉理工大学教授一学年化学。1991年4月,父亲和母亲一起参加了为期两个月的物理化学课程。随后,我的父母多次到中国交流经验,以提高中国的教育教学水平。 | 唐庆超(译) | 2021 | 国际人才交流2021，，11： | 0 |
| 18 | 提高KF-AlF_(3)-Al_(2)O_(3)熔体中Cu-Al基阳极的耐腐蚀性显示文摘采用恒电流和动电位极化技术研究经预氧化的和未经预氧化的Cu-Al基阳极(Cu-10Al和Cu-9.8Al-2Mn)在KF-AlF_(3)-Al_(2)O_(3)熔体中的阳极行为。将合金在700℃下进行短时间(8 h)氧化,然后在800℃下施以0.4 A/cm^(2)的电流密度进行1 h恒电流极化。测定扫描速率为0.01 V/s的动电位曲线。对在阳极表面冻结的熔体样品进行XRD分析,并在实验后对阳极进行SEM分析,以研究合金表面形成的氧化皮的物相。所有阳极材料的稳态电位都在2.30~2.50 V(vs Al/AlF_(3))范围内。根据动电位极化获得的数据计算阳极的腐蚀速率。结果表明,经预氧化的阳极比未经预氧化的阳极具有更低的腐蚀速率。 | Sai Krishna PADAMATA Andrey YASINSKIY Aleksandr SHABANOV Timofey BERMESHEV 杨酉坚 王兆文 曹导 Peter POLYAKOV | 2022 | Transactions of Nonferrous Metals Society of China2022，32，1： | 0 |
| 19 | 庆百年征程,不仅是中华民族的盛事更是国际外交的盛事显示文摘7月1日,中国隆重庆祝中国共产党成立100周年。在中国共产党的领导下,中国实现了民族独立与国家富强,今后将继续为实现中华民族伟大复兴而努力奋斗,为促进世界发展进步与构建人类命运共同体作出积极贡献。中国共产党的百年历史也是中俄两国人民的密切交往史。新时代中俄全面战略协作伙伴关系作为最佳实践的象征与典范,不仅让邻国受益,也加强了全球政治互信。 | Timofey Bakhvalov 张佳艺(译) | 2021 | 国际人才交流2021，，7： | 0 |
| 20 | Russia and China Relations in the Global Context显示文摘 | Timofei Bordachev | 2017 | 中国投资(中英文)2017，，13： | 0 |
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