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| 1 | Sub-synchronous Oscillations in Power Systems Caused by Grid-connected Wind Farms--A Survey of Mechanism Studies显示文摘Sub-synchronous oscillation(SSO)incidents caused by dynamic interaction between wind farms and power system grids can threaten safe and reliable operations.This paper investigates mechanism studies of SSOs in power systems induced by grid-connected wind farms.First,characteristics of several severe SSO incidents encountered by real power systems caused by grid-connected wind farms are introduced.Second,in terms of principles and responses,this paper illustrates the most commonly adopted mechanism investigation methods for SSOs,which include impedance-based analysis(IMA)and the openloop modal analysis(OMA)methods.Systematic reviews that summarize existing studies using the IMA and OMA methods are discussed in this paper.Furthermore,a discussion of the current research gaps in the investigation of SSOs in power systems caused by grid-connected wind farms is presented. | Chen Chen Wenjuan Du Haifeng Wang Tim Littler | 2018 | CSEE Journal of Power and Energy Systems2018，4，4： | 13 |
| 2 | Record-Setting Ocean Warmth Continued in 2019显示文摘Human-emitted greenhouse gases(GHGs)have resulted in a long-term and unequivocal warming of the planet(IPCC,2019).More than 90%of the excess heat is stored within the world's oceans,where it accumulates and causes increases in ocean temperature(Rhein et al.,2013;Abram et al.,2019). | Lijing CHENG John ABRAHAM Jiang ZHU Kevin ETRENBERTH John FASULLO Tim BOYER Ricardo LOCARNINI Bin ZHANG Fujiang YU Liying WAN Xingrong CHEN Xiangzhou SONG Yulong LIU Michael EMANN | 2020 | Advances in Atmospheric Sciences2020，37，2： | 7 |
| 3 | Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma显示文摘Hepatocellular 癌(HCC ) 在之中人的恶意最致命。在人的 multistep hepatocarcinogenesis 期间, genomic 获得在 proto-oncogenes 的激活代表重要机制。在许多情形,激活 oncogenes 为癌症治疗学作为预示的标记和目标两个都保持临床的含意。染色体 1q 拷贝的获得是在 HCC 的最经常检测的改变之一, 1q21 是最经常的最小的放大区域(3 月) 。更好的理解生理并且在 1q21 amplicon 以内的目标基因的 pathophysiological 角色将显著地在 HCC 致病改进我们的知识,并且可以导致忍受 1q21 的扩大的 HCC 的一个更有效的管理。如此的知识为 HCC 治疗为新治疗学的策略的发展有长期的含意。我们的研究组和其它,在 HCC 集中了于象 JTB, CKS1B,和 CHD1L 那样的 1q21 目标基因的鉴定和描述前进。在这评论,我们将在 1q21 amplicon 以内总结已知的目标基因的当前的科学知识, CHD1L 的精确 oncogenic 机制将详细被讨论。 | Leilei CHEN Tim Hon Man CHAN Xin-yuan GUAN | 2010 | Acta Pharmacologica Sinica2010，31，9： | 6 |
| 4 | Ampullary cancer of intestinal origin and duodenal cancer-A logical clinical and therapeutic subgroup in periampullary cancer显示文摘Periampullary cancers include pancreatic, ampullary, biliary and duodenal cancers. At presentation, the majority of periampullary tumours have grown to involve the pancreas, bile duct, ampulla and duodenum. This can result in difficulty in defining the primary site of origin in all but the smallest tumors due to anatomical proximity and architectural distortion. This has led to variation in the reported proportions of resected periampullary cancers. Pancreatic cancer is the most common cancer resected with a pancreaticoduodenectomy followed by ampullary(16%-50%), bile duct(5%-39%), and duodenal cancer(3%-17%). Patients with resected duodenal and ampullary cancers have a better reported median survival(29-47 mo and 22-54 mo) compared to pancreatic cancer(13-19 mo). The poorer survival with pancreatic cancer relates to differences in tumour characteristics such as a higher incidence of nodal, neural and vascular invasion. While small ampullary cancers can present early with biliary obstruction, pancreatic cancers need to reach a certain size before biliary obstruction ensues. This larger size at presentation contributes to a higher incidence of resection margin involvement in pancreatic cancer. Ampullary cancers can be subdivided into intestinal or pancreatobiliary subtype cancers with histomolecular staining. This avoids relying on histomorphology alone, as even some poorly differentiated cancers preserve the histomolecular profile of their mucosa of origin. Histomolecular profiling is superior to anatomic location in prognosticating survival. Ampullary cancers of intestinal subtype and duodenal cancers are similar in their intestinal origin and form a logical clinical and therapeutic subgroup of periampullary cancers. They respond to 5-FU based chemotherapeutic regimens such as capecitabine-oxaliplatin. Unlike pancreatic cancers, KRAS mutation occurs in only approximately a third of ampullary and duodenal cancers. Future clinical trials should group ampullary cancers of intestinal origin and duodenal cancers together given their similarities and their response to fluoropyrimidine therapy in combination with oxaliplatin. The addition of anti-epidermal growth factor receptor therapy in this group warrants study. | Manju D Chandrasegaram Anthony J Gill Jas Samra Tim Price John Chen Jonathan Fawcett Neil D Merrett | 2017 | World Journal of Gastrointestinal Oncology2017，9，10： | 4 |
| 5 | Distinctive Precursory Air–Sea Signals between Regular and Super El Ni os显示文摘Statistically different precursory air–sea signals between a super and a regular El Ni no group are investigated, using observed SST and rainfall data, and oceanic and atmospheric reanalysis data. The El Ni no events during 1958–2008 are first separated into two groups: a super El Ni no group(S-group) and a regular El Ni no group(R-group). Composite analysis shows that a significantly larger SST anomaly(SSTA) tendency appears in S-group than in R-group during the onset phase[April–May(0)], when the positive SSTA is very small. A mixed-layer heat budget analysis indicates that the tendency difference arises primarily from the difference in zonal advective feedback and the associated zonal current anomaly(u).This is attributed to the difference in the thermocline depth anomaly(D) over the off-equatorial western Pacific prior to the onset phase, as revealed by three ocean assimilation products. Such a difference in D is caused by the difference in the wind stress curl anomaly in situ, which is mainly regulated by the anomalous SST and precipitation over the Maritime Continent and equatorial Pacific. | Lin CHEN Tim LI Swadhin K.BEHERA Takeshi DOI | 2016 | Advances in Atmospheric Sciences2016，33，8： | 3 |
| 6 | Upper Ocean Temperatures Hit Record High in 2020显示文摘The long-term warming of the ocean is a critical indicator of both the past and present state of the climate system. It also provides insights about the changes to come, owing to the persistence of both decadal variations and secular trends,which the ocean records extremely well(Hansen et al., 2011;IPCC, 2013;Rhein et al., 2013;Trenberth et al., 2016;Abram et al., 2019). | Lijing CHENG John ABRAHAM Kevin ETRENBERTH John FASULLO Tim BOYER Ricardo LOCARNINI Bin ZHANG Fujiang YU Liying WAN Xingrong CHEN Xiangzhou SONG Yulong LIU Michael EMANN Franco RESEGHETTI Simona SIMONCELLI Viktor GOURETSKI Gengxin CHEN Alexey MISHONOV Jim REAGAN Jiang ZHU | 2021 | Advances in Atmospheric Sciences2021，38，4： | 2 |
| 7 | Three-type MJO Initiation processes over the Western Equatorial Indian Ocean显示文摘Thirty strong Madden–Julian Oscillation(MJO) events in boreal winter 1982–2001 are selected to investigate the triggering processes of MJO convection over the western equatorial Indian Ocean(IO).These MJO events are classified into three types,according to their dynamic and thermodynamic precursor signals in situ.In Type I,a remarkable increase in low-level moisture occurs,on average,7 days prior to the convection initiation.This low-level moistening is mainly due to the advection of the background mean moisture by easterly wind anomalies over the equatorial IO.In Type II,lower-tropospheric ascending motion anomalies develop,on average,4 days prior to the initiation.The cause of this ascending motion anomaly is attributed to the anomalous warm advection,set up by a suppressed MJO phase in the equatorial IO.In Type III,there are no clear dynamic and thermodynamic precursor signals in situ.The convection might be triggered by energy accumulation in the upper layer associated with Rossby wave activity fluxes originated from the midlatitudes. | MEI Shuangli Tim LI CHEN Wen | 2015 | Advances in Atmospheric Sciences2015，32，9： | 2 |
| 8 | Efficient photon coupling from a diamond nitrogen vacancy center by integration with silica fiber显示文摘A central goal in quantum information science is to efficiently interface photons with single optical modes for quantum networking and distributed quantum computing.Here,we introduce and experimentally demonstrate a compact and efficient method for the low-loss coupling of a solid-state qubit,the nitrogen vacancy(NV)center in diamond,with a single-mode optical fiber.In this approach,single-mode tapered diamond waveguides containing exactly one high quality NV memory are selected and integrated on tapered silica fibers.Numerical optimization of an adiabatic coupler indicates that near-unity-efficiency photon transfer is possible between the two modes.Experimentally,we find an overall collection efficiency between 16%and 37%and estimate a single photon count rate at saturation above 700 kHz.This integrated system enables robust,alignment-free,and efficient interfacing of single-mode optical fibers with single photon emitters and quantum memories in solids. | Rishi N Patel Tim Schröder Noel Wan Luozhou Li Sara L Mouradian Edward H Chen Dirk R Englund | 2016 | Light(Science & Applications)2016，5，1： | 2 |
| 9 | Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair显示文摘分区有缺陷者 3 (Par3 ) ,在 conservedPar3/Par6/aPKC 建筑群的一个关键部件,在房间极性的戏基础角色。此处,我们报导 Ku70 和通过试管内绑定试金的蛋白质由液体层析双人脚踏车质谱法跟随了的 Ku80 同样新奇的交往 Par3 的鉴定。Ku70/Ku80 蛋白质是 DNA 依赖的蛋白激酶(DNA-PK ) 的二个关键规章的子单元,它在修理双海滨脱氧核糖核酸裂缝(DSB ) 起一个必要作用。我们决定 Par3 withKu70/Ku80 的原子协会被 y 照耀(红外) 提高,有势力 DSB inducer。而且, DNA-PKcs, DNA-PK 的催化子单元,响应红外与 Par3/Ku70/Ku80 建筑群交往了。Par3over 表示或击倒分别地能够 up- 或 downregulat-ing DNA-PK 活动。而且, Par3 击倒的房间被发现在随机的原生质标志集成有缺点,在 DSB 修理追随者红外有缺点、对射线敏感,类似于 Ku70knockdown 房间的显型。这些调查结果作为 DNA-PK 建筑群的一个新奇部件识别 Par3 并且含有到 DSB 修理的房间极性的一个意外连接。 | Longhou Fang YiGuo Wang Dan Du Guang Yang Tim Tak Kwok Siu Kai Kong Benjamin Chen David J Chen Zhengjun Chen | 2007 | Cell Research2007，17，2： | 2 |
| 10 | CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients显示文摘 | Chen Leilei Chan Tim Hon Man Yuan Yun-Fei Hu Liang Huang Jun Ma Stephanie Wang Jian Dong Sui-Sui Tang Kwan Ho Xie Dan Li Yan Guan Xin-Yuan | 2010 | Journal of Clinical Investigation2010，，4： | 2 |
| 11 | Another Record: Ocean Warming Continues through 2021 despite La Nina Conditions显示文摘The increased concentration of greenhouse gases in the atmosphere from human activities traps heat within the climate system and increases ocean heat content(OHC). Here, we provide the first analysis of recent OHC changes through 2021 from two international groups. The world ocean, in 2021, was the hottest ever recorded by humans, and the 2021 annual OHC value is even higher than last year’s record value by 14 ± 11 ZJ(1 zetta J = 1021 J) using the IAP/CAS dataset and by16 ± 10 ZJ using NCEI/NOAA dataset. The long-term ocean warming is larger in the Atlantic and Southern Oceans than in other regions and is mainly attributed, via climate model simulations, to an increase in anthropogenic greenhouse gas concentrations. The year-to-year variation of OHC is primarily tied to the El Nino-Southern Oscillation(ENSO). In the seven maritime domains of the Indian, Tropical Atlantic, North Atlantic, Northwest Pacific, North Pacific, Southern oceans,and the Mediterranean Sea, robust warming is observed but with distinct inter-annual to decadal variability. Four out of seven domains showed record-high heat content in 2021. The anomalous global and regional ocean warming established in this study should be incorporated into climate risk assessments, adaptation, and mitigation. | Lijing CHENG John ABRAHAM Kevin ETRENBERTH John FASULLO Tim BOYER Michael EMANN Jiang ZHU Fan WANG Ricardo LOCARNINI Yuanlong LI Bin ZHANG Zhetao TAN Fujiang YU Liying WAN Xingrong CHEN Xiangzhou SONG Yulong LIU Franco RESEGHETTI Simona SIMONCELLI Viktor GOURETSKI Gengxin CHEN Alexey MISHONOV Jim REAGAN | 2022 | Advances in Atmospheric Sciences2022，39，3： | 1 |
| 12 | Detection of hepatitis B virus DNA in hepatocellular carcinoma: Analysis by hybridization with sub- genomic DNA fragments 显示文摘 | Chen J Y Tim J Harrison | | Hepatology0，8，3： | 1 |
| 13 | Remote Limb Ischemic Postconditioning Protects Against Neonatal Hypoxic–Ischemic Brain Injury in Rat Pups by the Opioid Receptor/Akt Pathway显示文摘 | Yilin Zhou Nancy Fathali Tim Lekic Robert P. Ostrowski Chunhua Chen Robert D. Martin Jiping Tang John H. Zhang | 2011 | Stroke2011，，： | 1 |
| 14 | Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair显示文摘The author affiliations were mixed up in the previous published version. The third fund number of National NaturalScience Foundation of China in the Acknowledgments was wrong, it should be '30270335'. The Shanghai MunicipalCouncil for Science and Technology (No.06DZ22032) was missed in the Acknowledgments. There are some labelingand production errors in Figure 2A, Figure 3B and 3C, Figure 5C, Figure 6B and 6E, Figure 7B and 7D. In Figure 2A,left panel 'A431' should be 'Par3'. In Figure 3B and 3C, 'anti-Par3CT' should be 'anti-Par3LCT', 'GST-Par3CT'should be 'GST-Par3LCT'. In Figure 5C, the second arrow indicating 'Lamin B' should be '[3-tubulin'. In Figure 6Bright panel, the molecular weight for ?-actin should be '43' instead of'200'. In Figure 6E, 'Par3' should be 'Par3i'. Themolecular weight for the DNA-PKcs panel should be the same as the p-DNA-PKcs. In Figure 7B, the time point '240'in the left panel should be '120'; in the right panel of Figure 7B, the title for the y axis should be 'DNA released (%)'.In Figure 7D, the title for the y axis should be 'Survival (%)', and the scale for the y axis should be '100, 10 and 1'. These corrections do not affect the conclusions of the study. We apologize for any inconvenience this may havecaused. | Longhou Fangt YiGuo Wang Dan Dut Guang Yang Tim Tak Kwok Siu Kai Kong Benjamin Chen David J Chen Zhengjun Chen | 2007 | Cell Research2007，17，6： | 1 |
| 15 | Hepatocellular carcinoma: Transcriptome diversity regulated by RNA editing显示文摘 | Yan Li Leilei Chen Tim Hon Man Chan Xin-Yuan Guan | 2013 | International Journal of Biochemistry and Cell Biology2013，，8： | 1 |
| 16 | Asymmetry of Atmospheric Responses to Two-Type El Nino and La Nina over Northwest Pacific显示文摘The mechanism for asymmetric atmospheric responses to the central Pacific(CP) El Ni?o and La Ni?a over the western North Pacific(WNP) is studied in this paper. The negative anomalies of rainfall over the key region of WNP are explained by diagnosing the column-integrated equations of moisture and moist static energy(MSE). It is revealed that the nonlinear advection of moist enthalpy is critical to introduce negative rainfall anomalies over the region. The anomalous easterly(westerly) in La Ni?a(CP El Ni?o) causes negative advection of anomalous moist enthalpy, inducing negative heating anomaly and an anticyclone anomaly in the WNP, which weakens(strengthens) the cyclone(anticyclone) in La Ni?a(CP El Ni?o). The MSE budget analysis shows a larger nonlinear term in CP El Ni?o than in eastern Pacific(EP) El Ni?o, inconsistent with the amplitudes of sea surface temperature anomalies. The reason is that the nonlinear term transforms to positive above 700 h Pa in EP El Ni?o, offsetting the negative advection below 700 h Pa and thus making the nonlinear term smaller. The nonlinear term is negative at low levels in CP El Ni?o, resulting in a larger nonlinear term. The stronger precipitation anomalies in the WNP during EP El Ni?o can be attributed to the linear moist enthalpy advection. The mean easterly wind at mid levels causes a larger(smaller) positive moist enthalpy advection in CP(EP) El Ni?o, due to a larger(smaller) moist enthalpy gradient, resulting in a positive(negative) linear moist enthalpy advection, which weakens(strengthens) the negative precipitation anomalies in the key region. | Mingcheng CHEN Tim LI Xiaohui WANG | 2019 | Journal of Meteorological Research2019，33，5： | 1 |
| 17 | Effects of Monsoon Trough Intraseasonal Oscillation on Tropical Cyclogenesis over the Western North Pacific*显示文摘 | Cao Xi Li Tim Peng Melinda Chen Wen Chen Guanghua | 2014 | Journal of the Atmospheric Sciences2014，，12： | 1 |
| 18 | Effects of monsoon trough interannual variation on tropical cyclogenesis over the western North Pacific显示文摘 | Cao Xi Li Tim Peng Melinda Chen Wen Chen Guanghua | 2014 | Geophysical Research Letters2014，，12： | 1 |
| 19 | Viral infections and colorectal cancer: A systematic review of epidemiological studies显示文摘 | Hongda Chen Xin‐Zu Chen Tim Waterboer Felipe Andres Castro Hermann Brenner | 2015 | Int. J. Cancer2015，，1： | 1 |
| 20 | 红外数据通讯(TrDC)显示文摘Vishay今天主要介绍IrDA在红外线高速数据传输的应用,这是一种无线的、应用光进行高资料量的传输.为什么要选用IrDA作为无线的数据传输呢?主要是IrDA是目前各种无线传输方式中最便宜的一种,供电电压可以做得更低,并且传输的速率远远高于其它方式的传输速率. | Tim Chen | 2004 | 世界电子元器件2004，，1： | 1 |
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