|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Do Long-Term Shareholders Benefit from Corporate Acquisitions? 显示文摘 | Tim L Vijh A M | 1997 | Journal of Finance1997,52,5: | 1 |
| 2 | Assessment of sediment and porewater after one year of sub aqueous capping of contaminated sediments in Hamilton Harbour, Canada显示文摘 | Azcue J M Zeman A J Alena Mudroch Fernando Rosa Tim Patterson | 1998 | Wat Sci Tech1998,37,67: | 1 |
| 3 | Biochar Incorporation into Pasture Soil Suppresses in situ Nitrous Oxide Emissions from Ruminant Urine Patches显示文摘 | Taghizadeh-Toosi Arezoo Clough Tim J Condron Leo M Sherlock Robert R Anderson Craig R Craigie Robin A | 2011 | EN2011,,2: | 1 |
| 4 | Label-free imaging of trabecular meshwork cells using Coherent Anti-Stokes Raman Scattering (CARS) microscopy显示文摘 | Tim C L David A A Omid M | 2011 | Mol Vis2011,17,: | 1 |
| 5 | Chitosan-alginate microcap- sules for oral delivery of egg yolk immunoglobulin (IgY) 显示文摘 | LI X Y JIN L J TIM A M | 2007 | J Agric Food Chem2007,55,8: | 1 |
| 6 | Unconventional shale- gas systems:The Mississippian Barnett Shale of north-central Texas as one model for thermogenic shale-gas assessment显示文摘 | Daniel M J Ronald J H Tim E R et a/ | 2008 | AAPG Bulletin2008,92,8: | 1 |
| 7 | Candidate High Spectral Resolution Infrared Indices for Crop Cover 显示文摘 | Tim J M Bruno A Mark D F | 1993 | Remote Sens Environ1993,46,1: | 1 |
| 8 | Proactive Personality and Job Performance:The Role of Job Crafting and Work Engagement 显示文摘 | BAKKER A B TIMS M DERKS D | 2012 | Human Relations2012,65,10: | 1 |
| 9 | Market Influence on the Low Carbon Energy Refurbishment of Existing Multi - residential Buildings 显示文摘 | Jonathan G B A Tim J Elizabeth M S | 2009 | Energy Policy2009,,37: | 1 |
| 10 | Job Crafting :Towards a New Model of Individual Job Redesign 显示文摘 | TIMS M BAKKER A B | 2010 | Journal of Industrial Psychology2010,36,2: | 1 |
| 11 | Influence of moisture con- tent and temperature on methane adsorption isotherm analy- sis for coals from a low-rank,biogenically sourced gas reser- voir显示文摘 | Peter J C Tim A M Tennille E M | 2008 | International Journal of Coal Geology2008,76,1: | 1 |
| 12 | Biochar Incorporation into Pasture Soil Suppresses in situ Nitrous Oxide Emissions from Ruminant Urine Patches显示文摘 | Taghizadeh-Toosi Arezoo Clough Tim J Condron Leo M Sherlock Robert R Anderson Craig R Craigie Robin A | 2011 | EN2011,,2: | 1 |
| 13 | Serum outperforms plasma in small extracellular vesicle microRNA biomarker studies of adenocarcinoma of the esophagus显示文摘BACKGROUND Circulating microRNAs(miRNAs)are potential biomarkers for many diseases.However,they can originate from non-disease specific sources,such as blood cells,and compromise the investigations for miRNA biomarkers.While small extracellular vesicles(sEVs)have been suggested to provide a purer source of circulating miRNAs for biomarkers discovery,the most suitable blood sample for sEV miRNA biomarker studies has not been defined.AIM To compare the mi RNA profiles between matched serum and plasma s EV preparations to determine their suitability for biomarker studies.METHODS Matched serum and plasma samples were obtained from 10 healthy controls and10 patients with esophageal adenocarcinoma.s EV isolates were prepared from serum and plasma using Exo Quick TM and quantified using Nano Sight.RNA was extracted from s EV preparations with the mi RNeasy Serum/Plasma kit and profiled using the Taqman Openarray q PCR.The overall mi RNA content and theexpression of specific mi RNAs of reported vesicular and non-vesicular origins were compared between serum and plasma s EV preparations.The diagnostic performance of a previously identified multi-mi RNA biomarker panel for esophageal adenocarcinoma was also compared.RESULTS The overall mi RNA content was higher in plasma s EV preparations(480 mi RNAs)and contained 97.5%of the mi RNAs found in the serum s EV preparations(412 mi RNAs).The expression of commonly expressed mi RNAs was highly correlated(Spearman’s R=0.87,P<0.0001)between the plasma and serum s EV preparations,but was consistently higher in the plasma s EV preparations.Specific blood-cell mi RNAs(hsa-mi R-223-3 p,hsa-mi R-451 a,mi R-19 b-3 p,hsa-mi R-17-5 p,hsa-mi R-30 b-5 p,hsa-mi R-106 a-5 p,hsa-mi R-150-5 p and hsa-mi R-92 a-3 p)were expressed at 2.7 to 9.6 fold higher levels in the plasma s EV preparations compared to serum s EV preparations(P<0.05).In plasma s EV preparations,the percentage of protein-associated mi RNAs expressed at relatively higher levels(Ct 20-25)was greater than serum s EV preparations(50%vs 31%).While the percentage of vesicle-associated mi RNAs expressed at relatively higher levels was greater in the serum s EV preparations than plasma s EV preparations(70%vs 44%).A 5-mi RNA biomarker panel produced a higher cross validated accuracy for discriminating patients with esophageal adenocarcinoma from healthy controls using serum s EV preparations compared with plasma s EV preparations(AUROC 0.80 vs 0.54,P<0.05).CONCLUSION Although plasma s EV preparations contained more mi RNAs than serum s EV preparations,they also contained more mi RNAs from non-vesicle origins.Serum appears to be more suitable than plasma for s EV mi RNAs biomarkers studies. | Karen Chiam George C Mayne Tingting Wang David I Watson Tanya S Irvine Tim Bright Lorelle T Smith Imogen A Ball Joanne M Bowen Dorothy M Keefe Sarah K Thompson Damian J Hussey | 2020 | World Journal of Gastroenterology2020,26,20: | 1 |
| 14 | Job Crafting at the Team and Individual Level: Implications for Work Engagement and Performance显示文摘 | TIMS M BAKKER A B DERKS D | 2013 | Group & Organization Management2013,38,4: | 1 |
| 15 | Development and vali- dation of the job crafting scale 显示文摘 | TIMS M BAKKER A B DERKS D | 2012 | Journal of Vocational Behavior2012,,80: | 1 |
| 16 | Examining Job Crafting from an Interpersonal Perspective: Is Employee Job Crafting Related to the Well-Being of Colleagues? 显示文摘 | TIMS M BAKKER A B DERKS D | 2015 | Applied Psychology2015,64,4: | 1 |
| 17 | Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells显示文摘 | Ivanov Andrei Beers Stephen A Walshe Claire A Honeychurch Jamie Alduaij Waleed Cox Kerry L Potter Kathleen N Murray Stephen Chan Claude H T Klymenko Tetyana Erenpreisa Jekaterina Glennie Martin J Illidge Tim M Cragg Mark S | 2009 | Journal of Clinical Investigation2009,,8: | 1 |
| 18 | Proactive personality and job performance: The role of job crafting and work engagement显示文摘 | Bakker A B Tims M Derks D | 2012 | Human Relations2012,65,10: | 1 |
| 19 | X-ray diffraction study into the effects of liming on the structure of collagen显示文摘 | Clark A M Tim J W Craig J K | 2006 | Biomacromolecules2006,7,8: | 1 |
| 20 | Subcutaneous and intermuscular fat characterization of dry-cured Iberian hams显示文摘 | Timón M L Ventanas J Carrapiso A I | 2001 | Meat Science2001,58,: | 1 |