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| 1 | 急性缺血性卒中的机械取栓治疗:ESO、ESMINT、ESNR和EAN共同支持的2014/2015 ESO-卡罗林斯卡卒中更新会议共识声明显示文摘这份卒中后机械取栓治疗共识声明的原始版本于2014年11月16—18日在斯德哥尔摩召开的欧洲卒中组织(European Stroke Organisation, ESO)-卡罗林斯卡卒中更新会议期间得到批准。根据会议安排,在2015年利用新的临床试验数据对该声明进行了更新。2015年2月,在瑞士伯尔尼召开的ESO冬季培训会期间组织了面对面会议对共识声明进行修订,然后通过电子邮件交换意见,最终版本得到各学会的认可。推荐意见与原始版本一致,证据等级更新到2015年2月20日为止,在2015年5月15日获得确认。ESO-卡罗林斯卡卒中更新会议的目的在于总结卒中治疗研究的最新进展并探讨如何将这些最新研究结果应用于临床实践。共识会议选择了一些议题进行讨论,与会者草拟一份共识声明并进行讨论。该声明接受了ESO指南委员会的指导。这份共识声明包括对急性卒中后机械取栓治疗的推荐意见,得到欧洲卒中组织ESO、欧洲神经微创治疗学会(European Society of Minimally Invasive Neurological Therapy, ESMINT)、欧洲神经放射学学会(European Society of Neuroradiology, ESNR)和欧洲神经病学学会(European Academy of Neurology, EAN)的支持。 | Nils Wahlgren Tiago Moreira Patrik Michel Thorsten Steiner Olav Jansen Christophe Cognard Heinrich P Mattle Wim van Zwam Staffan Holmin Turgut Tatlisumak Jesper Petersson Valeria Caso Werner Hacke Mikael Mazighi Marcel Arnold Urs Fischer Istvan Szikora Laurent Pierot Jens Fiehler Jan Gralla Franz Fazekas Kennedy R Lees 高洁 徐格林 | 2016 | 国际脑血管病杂志2016，24，1： | 5 |
| 2 | Diagnosis and management of laryngopharyngeal reflux disease显示文摘 | Pontes P Tiago R | 2006 | Curr Opin Otolaryngol Head Neck Surg2006，14，： | 1 |
| 3 | Target costing operationalization during product development:Model and application显示文摘 | Tiago P F Francisco J K N Michael R D | 2009 | Int J Production Economics2009，，118： | 1 |
| 4 | Mitochondrial haplogroupHI is protective for ischemic stroke in Portuguese patients 显示文摘 | Alexandra R Benedita VF Tiago K | 2008 | BMCMed Genetics2008，57，： | 1 |
| 5 | Scanning electron microscopy and microbiological evaluation of equine burn wound repair after platelet-rich plasma gel treatment显示文摘 | Maciel F B De Rossi R Tiago J C Modolo | 2012 | Burns:Journal of the International Society for Burn Injuries2012，38，7： | 1 |
| 6 | The influence of stroke mechanics into energy cost of elite Swimmers 显示文摘 | Tiago M Barbosa Femandes R J | 2008 | European Journal of Applied Physiology2008，103，1： | 1 |
| 7 | Analysis and simulation of“low-cost”strategies to reduce fuel consumption and emissions in conventional gasoline light-duty vehicles显示文摘 | Carla S Marc R Tiago F | 2009 | Energy Conversion and Management2009，50，2： | 1 |
| 8 | Three endothelial nitric oxide(NOS3) gene polymorphisms in hypertensive and normotensive individuals:meta-analysis of 53 studies reveal evidence of publication bias显示文摘 | Tiago V Pereira Martina R | 2007 | Journal of Hypertension2007，25，： | 1 |
| 9 | Natural melanin: A potential pH-responsive drug release device 显示文摘 | MARCO A RAQUEL V TIAGO R | 2014 | Int J Pharm2014，469，1： | 1 |
| 10 | Control of stomatal aperture and carbon uptake by deficit irrigation in two grapevine cultivars显示文摘 | Claudia R de Souza Joao P Maroco Tiago P dos Santos | 2005 | Agriculture Ecosystems and Environment2005，，106： | 1 |
| 11 | The role of science parks and business incubators in converging countries: Evidence from Portugal 显示文摘 | Tiago R Elsa H | 2010 | Technovation2010，30，4： | 1 |
| 12 | Effects of deficit irrigation strategies on cluster microclimate for improving fruit composition of Moscatel field-grown grapevines显示文摘 | Tiago P S Carlos M L Lucilia M R | 2007 | Scientia Horticulturae2007，112，3： | 1 |
| 13 | Aerobic exercise reduces oxidative stress and improves vascular changes of small mesenteric and coronary arteries in hypertension显示文摘 | Fernanda R Roque Ana M Briones Ana B García‐Redondo María Galán Sonia Martínez‐Revelles Maria S Avenda?o Victoria Cachofeiro Tiago Fernandes Dalton V Vassallo Edilamar M Oliveira Mercedes Salaices | 2013 | Br J Pharmacol2013，，3： | 1 |
| 14 | Analysis and Simulation of 'Low-Cost' Strategies to Reduce Fuel Consumption and Emissions in Conven- tional Gasoline Light-duty Vehicles 显示文摘 | Carla S Marc R Tiago F | 2009 | Energy Conversion and Management2009，50，2： | 1 |
| 15 | Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death显示文摘 | Brohem C A Massaro R R Tiago M | 2012 | Pigment Cell Melanoma Res2012，25，3： | 1 |
| 16 | Partial root zone drying effects on growth and fruit quality of field-grown grapevines(Vitis vninifera)显示文摘 | Tiago P S Carlos M L Lucilia M R | | 0，，06： | 1 |
| 17 | CODE-EHR:临床研究中运用结构化电子医疗记录的最佳实践框架显示文摘改善患者生存质量是全球临床医学的发展目标,大数据是实现其发展的关键所在。技术进步使结构化电子医疗记录得以常规化,也可能会改善缺失重要临床证据的问题。虽然大数据及其相关分析在新冠大流行期间发挥了重要作用,但也存在严重的缺陷。证实、核验、数据隐私以及对科学研究社会责任的践行是一项重要挑战。欧洲心脏病协会和BigData@Heart联盟已经收集了包括患者代表、临床医生、科研人员、监管机构、期刊编辑和企业代表在内的多元化国际参与者,提出了CODE-EHR的最低标准框架。为改进研究设计、提高信息透明度提供方法手段,同时为实现医疗保健数据的稳健并能够有效运用制定了技术路线图。 | Dipak Kotecha Folkert W Asselbergs Stephan Achenbach Stefan DAnker Dan Atars Colin Baigent Amitava Banerjee Birgit Beger Cunnar Brobert Barbara Casadei Cinzia Ceccarelli Martin R Cowie Filippo Crea Maureen Cronin Spiros Denaxas Andrea Derix Donna Fitzsimons Martin Fredriksson Chris PGale Georgios V Ckoutos Wim Goettsch Harry Hemingway Martin Ingvaris Adrian Jonas's Robert Kazmierski Susanne Logstrup R Thomas Lumbers Thomas F Lischer Paul McGreavy leana L Pina Lothar Roesiga Carl Steinbeisser Mats Sundgren Benoit Tyl Chislaine van Thiel Kees van Bochove Panos EVardas Tiago Villanueva Marilena Vrana Wim Weber Franz Weidinger Stephan Windecker Angela Wood Diederick E Grobbee 创新药物计划BigData@Heart联盟 欧洲心脏病协会 CODE-EHR国际共识小组 宋奇繁(译) 汪奕名(译) | 2022 | 英国医学杂志中文版2022，25，12： | 0 |
| 18 | Osteomodulin downregulation is associated with osteoarthritis development显示文摘Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis(OA), and osteomodulin(OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However, the functions of OMD remain poorly understood, specifically in vivo. We used Omd knockout and overexpressing male mice and mutant zebrafish to study its roles in bone and cartilage metabolism and in the development of OA. The expression of Omd is deeply correlated with bone and cartilage microarchitectures affecting the bone volume and the onset of subchondral bone sclerosis and spontaneous cartilage lesions. Mechanistically, OMD binds to RANKL and inhibits osteoclastogenesis, thus controlling the balance of bone remodeling. In conclusion, OMD is a key factor in subchondral bone sclerosis associated with OA. It participates in bone and cartilage homeostasis by acting on the regulation of osteoclastogenesis. Targeting OMD may be a promising new and personalized approach for OA. | Jérémie Zappia Qiao Tong Renée Van der Cruyssen Frederique MFCornelis Cécile Lambert Tiago Pinto Coelho Juliane Grisart Erika Kague Rik JLories Marc Muller Dirk Elewaut Chrissy LHammond Christelle Sanchez Yves Henrotin | 2023 | Bone Research2023，11，4： | 0 |
| 19 | A new heparin fragment decreases liver ischemia-reperfusion injury显示文摘To the Editor:Ischemia-reperfusion injury following surgery and transplantation can lead to irreversible multiorgan failure.Intracellular calcium overload is associated to cellular death during ischemiareperfusion.A recently discovered heparin fragment (HF),trisulfated disaccharide (TD),that acts on sodium-calcium exchanger(NCX) decreasing intracellular Ca^(2+),showed effectiveness on protecting hepatocytes from ischemia-reperfusion injury [1]. | Enio R Vasques Estela RR Figueira Joel A Rocha-Filho Cinthia Lanchotte Jorge LS Ximenes Helena B Nader Ivarne LS Tersariol Marcelo A Lima Tiago Rodrigues JoséEM Cunha Eleazar Chaib Luiz AC D’Albuquerque Flávio HF Galvão | 2022 | Hepatobiliary & Pancreatic Diseases International2022，21，2： | 0 |
| 20 | Lithic soils in the semi-arid region of Brazil:edaphic characterization and susceptibility to erosion显示文摘Soils(Leptosols or Epileptic Regosols)with lithic contact at a depth of 50 cm occupy almost 20%of the Brazilian semi-arid region.These lithic soils are susceptible to erosion due to faster saturation of water-holding capacity during rainfall,which accelerates the beginning of runoff.However,erosion traits of lithic soils in the semi-arid region of Brazil are less studied.The aim of this study was to characterize the soil and landscape attributes in areas with Neossolos Litólicos(Entisols)in the Caatinga biome to identify region of high susceptibility to erosion.Results showed that the soils were characterized by a sandy texture,soil structure with poor development and low content of organic carbon.These attributes increase susceptibility to erosion and reduce water storage capacity,especially in the states of Cearáand Sergipe.In these states,the content of rock fragments in the soil reaches 790 g/kg.High contents of silt and fine sand,high silt/clay ratio,predominance of Leptosols and strong rainfall erosivity were observed in Piauíand northwestern Ceará.A very high degree of water erosion was observed in the states of Pernambuco and Paraíba.Despite the low degree of erosion observed in the state of Bahia,it is highly susceptible to erosion due to the predominance of very shallow soils,rugged relief and high values of rainfall erosivity.Lower vulnerability was observed in the state of Alagoas because of its more smoothed relief,greater effective soil depth,thicker A horizon of soil and lower rainfall erosivity.In general,the characteristics that intensify the susceptibility to erosion in the Caatinga biome are those soil structures with poor development or without aggregation,low contents of organic carbon,high contents of silt and fine sand,high values of silt/clay ratio and rugged relief in some regions.This study collected information contributing to a better characterization of soils with lithic contact in the semi-arid region of Brazil.In addition,regions with a higher susceptibility to erosion were identified,revealing insights that could help develop strategies for environmental risk mitigation. | Carlos R PINHEIRO JUNIOR Conan A SALVADOR Tiago R TAVARES Marcel C ABREU Hugo S FAGUNDES Wilk S ALMEIDA Eduardo C SILVA NETO Lúcia H C ANJOS Marcos G PEREIRA | 2022 | Journal of Arid Land2022，14，1： | 0 |
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