维普期刊资源整合服务平台（V6.5）

42篇 您的检索式：作者名="Tesson L"

选中清除导出查看参考文献查看引证文献引用追踪共3页首页上一页第1页下一页末页 /3 跳转

	题名	作者	年代	出处	被引量
1	A Rapid and Cost-Effective Method for Genotyping Genome-Edited Animals:A Heteroduplex Mobility Assay Using Microfluidic Capillary Electrophoresis显示文摘The recent emergence and application of engineered endonucleases have led to the development of genome editing tools capable of rapidly implementing various targeted genome editions in a wide range of species.Moreover,these novel tools have become easier to use and have resulted in a great increase of applications.Whilst gene knockout(KO) or knockin(KI) animal models are relatively easy to achieve,there is a bottleneck in the detection and analysis of these mutations.Although several methods exist to detect these targeted mutations,we developed a heteroduplex mobility assay on an automated microfluidic capillary electrophoresis system named HMA-CE in order to accelerate the genotyping process.The HMA-CE method uses a simple PCR amplification of genomic DNA(gDNA) followed by an automated capillary electrophoresis step which reveals a heteroduplexes(HD) signature for each mutation.This allows efficient discrimination of wild-type and genome-edited animals down to the single base pair level.	Vanessa Chenouard Lucas Brusselle Jean-Marie Heslan Séverine Remy Séverine Ménoret Claire Usal Laure-Hélène Ouisse Tuan Huy NGuyen Ignacio Anegon Laurent Tesson	2016	Journal of Genetics and Genomics2016，43，5：	4
2	Modification of enzymatically amplified DNA for the detection of point mutations显示文摘	Haliassos A Chomel JC Tesson L	1989	Nucleic Acids Res1989，17，9：	1
3	LacZ transgenic rats tolerant for beta-galactosidase: recipients for gene transfer studies using lacZ as a reporter gene显示文摘	Menoret S Aubert D Tesson L	2002	Hum Gene Ther2002，13，：	1
4	Knockout rats generated by embryo microinjection of TALENs 显示文摘	Tesson L Usa1 C Menoret S etal	2011	Nat Biotechnol2011，29，8：	1
5	查看详情显示文摘	Charreau B Cassard A Tesson L		0，，：	1
6	In vitro and in vivo gene transfer in the rat: characterization of recombinant adenoviral vectors for rat interleukin-4 or interleukin-10cDNA显示文摘	David A Cassard A Tesson L	1997	Transplant Proc1997，29，3：	1
7	Carbon monoxide inhibits TLR-induced dendritic cell immu nogenieity显示文摘	R6my S Blancou P Tesson L Tardif V Brion R Royer P J	2009	J Immunol2009，182，：	1
8	Knockout rats gener- ated by embryo microinjection of TALENs显示文摘	Tesson L Usal C M6noret S	2011	Nat Biotech- nol2011，29，8：	1
9	New lines of GFP transgenic rats relevant for regenerative medicine and gene therapy显示文摘	Remy S Tesson L Usal C		0，，05：	1
10	Knockout rats generated by embryo microinjection of TALENs 显示文摘	Tesson L Usal C Menoret S	2011	Nat Biotechnol2011，29，8：	1
11	Rapid and accurate determination of zygosity in transgenic animals by real-time quantitative PCR显示文摘	Tesson L Heslan J M Menoret S	2002	Transgenic Res2002，11，1：	1
12	Knockout rats generated by embryo microinjection of TALENs 显示文摘	Tesson L Usal C Menoret S	2011	Nat Biotechnol2011，29，8：	1
13	Induction of long-term cardiac allograft survival by heme oxygenase-1 gene transfer显示文摘	Braudeau C Bouchet D Tesson L	2004	Gene Ther2004，11，8：	1
14	Carbon monoxide inhib- its TLR-induced dendritic cell immunogenicity 显示文摘	REMY S BLANCOU P TESSON L	2009	J Immunol2009，182，：	1
15	In vitro and in vivo gene transfer in the rat:characterization of recombinant adenoviral vectors for rat interleukin-4 or interleukin-10cDNA显示文摘	David A Cassard A Tesson L	1997	Transplant Proce1997，29，3：	1
16	Knockout rats generated by em-bryo microinjection of TALENs显示文摘	Tesson L Usal C Menoret S	2011	Nat Biotechnol2011，29，8：	1
17	New lines of GFP transgenic rats relevant for regenerative medicine and gene therapy显示文摘	Remy S Tesson L Usal C	2010	Transgenic Res2010，19，5：	1
18	Carbon monoxide inhibits TLR-induced dendritic cell immunogenici 显示文摘	R6my S Blancou P Tesson L	2009	J Immunol2009，182，4：	1
19	Transgenic modifications of the rat genome显示文摘	Tesson L Cozzi J Ménoret S		0，，05：	1
20	Induction of long-term cardiac allograft survival by heine oxygenase- 1 gene transfer显示文摘	Braudeau C Bouchet D Tesson L	2004	Gene Ther2004，11，8：	1

返回顶部每页显示：

共3页首页上一页第1页下一页末页 /3 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示