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| 1 | 肝炎 E : 传染病学和预防显示文摘 Hepatitis E is caused by the hepatitis E virus (HEV), the major etiologic agent of enterically transmitted non-A hepatitis worldwide. HEV is responsible for major outbreaks of acute hepatitis in developing countries, especially in many parts of Africa and Asia. The HEV is a spherical, non-enveloped, single-stranded, positive sense RNA virus that is approximately 32 nm to 34 nm in diameter and is the only member in the family Hepeviridae and genus Hepevirus. There are four distinct genotypes of HEV (genotypes 1-4). While genotype 1 is predominantly associated with large epidemics in developing countries, genotype 3 has recently emerged as a significant pathogen in developed countries. The clinical manifestations and the laboratory abnormalities of hepatitis E are not distinguishable from that caused by other hepatitis viruses. However, high mortality among pregnant women particularly during the third trimester distinguishes HEV from other causes of acute viral hepatitis. Specific etiologic diagnosis among infected cases can be made by serological testing or detection of viral nucleic acid by reverse transcription polymerase chain reaction. Although there are vaccine candidates that had been shown to be safe and efficacious in clini-cal trials, none are approved currently for use. There is no specific therapy for acute hepatitis E as treatment remains supportive. | Eyasu H Teshale Dale J Hu | 2011 | World Journal of Hepatology2011，3，12： | 9 |
| 2 | Antiviral Therapy for Chronic Hepatitis B Virus Infection and Development of Hepatocellular Carcinoma in a US Population显示文摘 | Stuart C. Gordon Lois E. Lamerato Loralee B. Rupp Jia Li Scott D. Holmberg Anne C. Moorman Philip R. Spradling Eyasu H. Teshale Vinutha Vijayadeva Joseph A. Boscarino Emily M. Henkle Nancy Oja–Tebbe Mei Lu | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 2 |
| 3 | Making hepatitis E a vaccinepreventable disease显示文摘 | TESHALE E WARD J W | 2015 | N Engl J2015，372，10： | 1 |
| 4 | Apolipoprotein E and protection against hepatitis E viral infection in American non‐Hispanic blacks显示文摘 | Lyna Zhang Ajay Yesupriya Man‐Huei Chang Eyasu Teshale Chong‐Gee Teo | 2015 | Hepatology2015，，5： | 1 |
| 5 | Hepatitis E epidemic,Uganda显示文摘 | Teshale H | | 0，，01： | 1 |
| 6 | The two faces of hepatitis E virus 显示文摘 | Teshale EH Hu DJ Holmberg SD | 2010 | Clin Infect Dis2010，51，3： | 1 |
| 7 | APRI and FIB-4 are good predictors of the stage of liver fibrosis in chronic hepatitis B: the Chronic Hepatitis Cohort Study (CHeCS)显示文摘 | Teshale E Lu M Rupp LB | 2014 | J Viral Hepat2014，21，12： | 1 |
| 8 | Evidence of person-toperson transmission of hepatitis E virus during a large outbreak in Northem Uganda显示文摘 | Teshale EH Grytdal SP Howard C | | 0，，07： | 1 |
| 9 | Effect of hepatitis C infection on progression of HIV diseast and early response to initial antiretroviral therapy 显示文摘 | Sullivan PS Hanson DL Teshale EH Wotring LL BrooksJT | 2006 | AIDS2006，20，8： | 1 |
| 10 | The two faces of hep- atitis E virus显示文摘 | Teshale EH Hu DJ Holmberg SD | 2010 | Clin Infect Dis2010，51，3： | 1 |
| 11 | Investigation on infectious bursal disease out- break in Debre Zeit, Ethiopia 显示文摘 | Aschalew Zeleke Esayas Gelaye Teshale Sori | 2005 | International Journal of Poultry Science2005，4，7： | 1 |
| 12 | Relationship Between Level of Hepatitis B Virus DNA and Liver Disease: A Population-based Study of Hepatitis B e Antigen–Negative Persons With Hepatitis B显示文摘 | Brian J. McMahon Lisa Bulkow Brenna Simons Yuhong Zhang Susan Negus Chriss Homan Philip Spradling Eyasu Teshale Daryl Lau Mary Snowball Stephen E. Livingston | 2014 | Clinical Gastroenterology and Hepatology2014，，4： | 1 |
| 13 | Evidence of person -to - person transmission of hepatitis E virus during a large outbreak in Northern Uganda显示文摘 | Teshale EH Grytdal SP Howard C | 2010 | Clin Infect Dis2010，50，7： | 1 |
| 14 | Hepatitis Eepidemic,Uganda显示文摘 | Teshale EH Howard CM Grytdal SP | 2010 | Emerg Infect Dis2010，16，1： | 1 |
| 15 | Decline in hepatitis E virus antibody prevalence in the united states from 1988 -1994 to 2009 -2010显示文摘 | Teshale EH Denniston MM DrobeniucJ | 2015 | J Infect Dis2015，211，3： | 1 |
| 16 | Evi- dence of person-to-person transmission of hepatitis E virus during a large outbreak in Northern Uganda显示文摘 | TESHALE E H GRYTDAL S P HOWARD C | 2010 | Clin In- fect Dis2010，50，7： | 1 |
| 17 | Decline in Hepatitis E Virus Antibody Prevalence in the United States From1988-1994to 2009-2010显示文摘 | Teshale E H Denniston M M Drobeniuc J Kamili S Chong-Gee T Holmberg S D | 2015 | J Infect Dis2015，211，3： | 1 |
| 18 | The two faces of hepatitis E virus 显示文摘 | TESHALE EH HU DJ HOLMBERG SD | 2010 | Clin Infect Dis2010，51，3： | 1 |
| 19 | Socio-ecological vulnerability to climate change/variability in central rift valley,Ethiopia显示文摘Climate change/variability and environmental degradation have increased in the central rift valley of Ethiopia,which in turn making the people inhabiting in that ecosystem more vulnerable to the impacts.The purposes of this study were to assess the vulnerability of households andagro-ecosystems to climate change and environmental degradation and the factors determining vulnerabilities in the central rift valley,Ethiopia.Data were collected between November 2014 and May 2015 by interviewing 355 respondents.This has been supplemented with focus group discussions and key informant interviews.The indicator and matrix methods were used to describe socio-ecological vulnerabilities.The resultsshowed that about 9%of the respondents were highly vulnerable to climate change/variability,and environmental degradation.Households in the lowland have the largest proportion of high vulnerable households(60%),while households in highland have the largest proportion of low vulnerable households(30%).In the lowland agro-ecology,the adaptive capacity component has contributed the largest share to household's vulnerability index to the impacts of climate change/variability and environmental degradation.The sensitivity component has higer contribution in highland agro-ecology and the exposure component in the midland agro-ecology.There were variations of income deviation between agro-ecologies that lead to variation in vulnerability of households.Household vulnerability index has shown a very light negative correlation with livelihood diversification index.The poorest households with little share of the total income distribution and with low livelihood diversity index,were the most vulnerable.The results showed that the highest exposure index on ecosystem functions and agricultural performance were in the lowland agro-ecology.This study highlighted the need to assess the social and ecological vulnerabilities in integrated approach as singling out one from the other is difficult.That is,social vulnerability impacts ecological vulnerability and vice versa. | Zenebe MEKONNEN Teshale WOLDEAMANUEL Habtemariam KASSA | 2019 | Advances in Climate Change Research2019，10，1： | 1 |
| 20 | APRI and FIB ‐4 are good predictors of the stage of liver fibrosis in chronic hepatitis B : the Chronic Hepatitis Cohort Study ( CH e CS )显示文摘 | E. Teshale M. Lu L. B. Rupp S. D. Holmberg A. C. Moorman P. Spradling V. Vijayadeva J. A. Boscarino M. A. Schmidt S. C. Gordon | 2014 | J Viral Hepat2014，，12： | 1 |
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