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| 1 | Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome显示文摘AIM:To investigate the correlations between selfreported symptoms of irritable bowel syndrome(IBS) and the gastrointestinal(GI) microbiota composition.METHODS:Fecal samples were collected from a total of 44 subjects diagnosed with IBS.Their symptoms were monitored with a validated inflammatory bowel disease questionnaire adjusted for IBS patients.Thirteen quantitative real-time polymerase chain reaction assays were applied to evaluate the GI microbiota composition.Eubacteria and GI bacterial genera(Bifidobacterium,Lactobacillus and Veillonella),groups(Clostridium coccoides/Eubacterium rectale,Desulfovibrio desulfuricans) and distinct bacterial phylotypes [closest 16S rDNA sequence resemblance to species Bifidobacterium catenulatum,Clostridium cocleatum,Collinsella aerofaciens(C.aerofaciens),Coprococcus eutactus(C.eutactus),Ruminococcus torques and Streptococcus bovis ] with a suspected association with IBS were quantified.Correlations between quantities or presence/absence data of selected bacterial groups or phylotypes and various IBSrelated symptoms were investigated.RESULTS:Associations were observed between subjects' self-reported symptoms and the presence or quantities of certain GI bacteria.A Ruminococcus torques(R.torques)-like(94% similarity in 16S rRNA gene sequence) phylotype was associated with severity of bowel symptoms.Furthermore,among IBS subjects with R.torques 94% detected,the amounts of C.cocleatum 88%,C.aerofaciens-like and C.eutactus 97% phylotypes were significantly reduced.Interesting observations were also made concerning the effect of a subject's weight on GI microbiota with regard to C.aerofaciens like phylotype,Bifidobacterium spp.and Lactobacillus spp.CONCLUSION:Bacteria seemingly affecting the symptom scores are unlikely to be the underlying cause or cure of IBS,but they may serve as biomarkers of the condition. | Erja Malinen Lotta Krogius-Kurikka Janne Nikkil Airi Palva Anna Lyra Anne Jskelinen Teemu Rinttil Terttu Vilpponen-Salmela Atte Johannes von Wright | 2010 | World Journal of Gastroenterology2010，16，36： | 13 |
| 2 | 波罗的海蓝藻赤潮的历史显示文摘波罗的海所发生的赤潮,主要是由Nodudaria spupmigena和Aphanizomenon sp.这两种蓝藻形成的。有关这些赤潮的长期变化记录可以从过去(1887~1938年)和现代(1974~1998年)出版的浮游植物数据记录中找到。通过各种不同的收集、分析方法已经得到了大量的数据,为了提高这些数据的可比性,人们正在不断地尝试老的、新的采样方式与固定方法。100多年前,浮游生物就做为鱼类的食物来源而引起了人们的兴趣;富营养化问题主要出现在南部的礁湖(haffs)以及大城市附近的海边水域。二战前,很少有关于开阔海域赤潮的报道。在过去的营养环境中,Nodudaria spupmigena和Aphanizomenon sp.的数量还很少,从1887~1938年的137个夏季采样中表明它们的丰度还没有达到过最高峰。在现在的营养环境中,高丰度是非常普遍的,这两个物种的数目范围相对于过去的营养环境来说有了明显的增长。自20世纪60年代以来,蓝藻赤潮在波罗的海本体与芬兰湾的开阔海域是非常常见的,这表明了营养物已经高度丰富。 | Terttu Finni Kaisa Kononen Riitta Olsonen Kerstin Wallstrm 马志华 | 2001 | AMBIO-人类环境杂志2001，30，4： | 2 |
| 3 | Diagnosis and pharmacotherapy of stable chronic obstructive pulmonary disease:the finnish guidelines显示文摘 | Hannu Kankaanranta Terttu Harju Maritta Kilpelinen | 2015 | Basic Clin Pharmacol Toxicol2015，116，4： | 1 |
| 4 | PCDD,PCDF,and PCB concentrations in human milk from two areas in Finland显示文摘 | TERTTU V SEPPO S JOUNI J J | 1997 | Chemosphere1997，34，12： | 1 |
| 5 | Drinking water chlorination and cancer – a historical cohort study in Finland显示文摘 | Meri Koivusalo Eero Pukkala Terttu Vartiainen Jouni J.K. Jaakkola Timo Hakulinen | 1997 | Cancer Causes and Control1997，，2： | 1 |
| 6 | The difficulties in assessing the impact of EU framework Programmes显示文摘 | TERTTU LUUKKONEN | 1998 | Research Policy1998，，27： | 1 |
| 7 | Changes in content of microbially available phosphorus, assimilable organic carbon and microbial growth potential during drinking water treatment processes 显示文摘 | Markku J L Ilkka T M Terttu V | 2002 | Wat Res2002，36，15： | 1 |
| 8 | A new sensitive biosssay for determination of microbially available phosphorus in water显示文摘 | Ilkka T Miettinen Terttu Vartiainen | 1999 | Appl Environ Microbiol1999，65，5： | 1 |
| 9 | Dete Mentation of Assimilable Organic Carbon in Humus- rich Drinking Waters显示文摘 | ILKKA T M TERTTU V PERTTI J M | 1999 | Wat Res1999，33，10： | 1 |
| 10 | Microbially Available Organic Carbon, Phosphorus and Microbial Growth in Ozonated Drinking Water显示文摘 | MARKKU J L ILKKA T M TERTTU V | 2001 | Wat Res2001，35，7： | 1 |
| 11 | Changes in Content of Microbially Available Phosphorus, AssimilAble Organic Carbon and Microbial Growth Potential During Drinking Water Treatment Processes 显示文摘 | MARKKU J L ILKKA M T TERTTU V | 2002 | Wat Res2002，36，： | 1 |
| 12 | Use of olive oil for soll extraction and uhraviolet degradation of polychlorinated dibenzo-p-Dioxins and dibenzofurans Environ显示文摘 | Pirjo I Tuula T Terttu V | 2001 | Sci Technol2001，35，： | 1 |
| 13 | Use of olive oil for soil extraction and uhraviolet degradation of polyehlorinated dibenzo p Dioxins and dibenzofurans Environ显示文摘 | Pirjo I Tuula T Terttu V | 2001 | Sci Technol2001，，35： | 1 |
| 14 | A New Sensitive Bioassay for Determination of Microbially Available Phosphorus in Water显示文摘 | MARKKU J L ILKKA M T TERTTU V | 1999 | Appl Environ Micmbiol1999，65，5： | 1 |
| 15 | Development of supercritical fluid extraction with a solid-phase trapping for fast estimation of toxic load of polychlorinated dibenzo-p-dioxins-Dibenzofurans in sawmill soil显示文摘 | Mari Mannila Jaana Koistinen Terttu Vartiainen | 2002 | Journal of Chromatography A2002，975，： | 1 |
| 16 | Formation of PCDD/PCDF显示文摘 | Helena Manninen Annikki Perki? Terttu Vartiainen Juhani Ruuskanen | 1996 | Environmental Science and Pollution Research1996，，3： | 1 |
| 17 | Understanding patterns of international scientific collaboration 显示文摘 | Terttu Luukkonen Olle Persson Gunnar Sivertsen | 1992 | Science Technology & Human Values1992，17，1： | 1 |
| 18 | 'Everything is plentiful-Except attention' Attention data of scientific journals on social web tools显示文摘 | Terttu Kortelainen Mari Katvala | | 0，，04： | 1 |
| 19 | Estimates of microbial quality and concentration of copper in distributed drinking water are highly dependent on sampling strategy显示文摘 | Markku J. Lehtola Ilkka T. Miettinen Arja Hirvonen Terttu Vartiainen Pertti J. Martikainen | 2006 | International Journal of Hygiene and Environmental Health2006，，6： | 1 |
| 20 | Glutathione-S-transfe-rases in lung and sputum specimens,effects of smoking andCOPD severity显示文摘 | TERTTU VUOKKO L KINNULA | 2008 | Respir Research2008，9，13： | 1 |
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