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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS. | Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight | 2010 | Cellular & Molecular Immunology2010，7，3： | 3 |
| 3 | FRP-Strengthened RC beams( I ):Review of debonding strength models 显示文摘 | Smith S T Teng J G | 2002 | Engineering Structures2002，，24： | 2 |
| 4 | Reduction of NO with NH3 over carbon catalysts-the influence of carbon surfaces structure and the global kinetics显示文摘 | Teng H Hsu Y F Tu Y T | 1999 | Applied Catalysis B: Environmental1999，20，2： | 2 |
| 5 | Instabihties of strategic alliances:An internal tensions perspective显示文摘 | Das T K Teng B S | 2000 | Organization Science2000，11，1： | 1 |
| 6 | Multivariate analysis of soil heavy metal pollution and landscape pattern in Changhua County in Taiwan 显示文摘 | LIN Y P TENG T P CHANG T K | 2002 | Landscape and Urban Planning2002，62，1： | 1 |
| 7 | Hybrid FRP-concrete-steel tubular col- umns:concept and behavior 显示文摘 | Teng J G Yu T Wong Y L | 2007 | Construction and Building Mate- rials2007，21，4： | 1 |
| 8 | A resource-based theory of strategic alliances显示文摘 | DAS T K TENG Bing Sheng | 2000 | Journal of Management2000，26，1： | 1 |
| 9 | Optimal pricing and ordering policy under permissible delay in payments显示文摘 | Teng J T Chang C T Goyal S K | 2005 | International Journal of Production Economics2005，97，： | 1 |
| 10 | Preparation of activated carbon from bituminous coal with phosphoric acid activation显示文摘 | Teng H Yeh T S Hsu L Y | 1999 | Carbon1999，36，： | 1 |
| 11 | A resource - based theory of stra- tegic alliances 显示文摘 | Das T K Teng B - S | 2000 | Journal of Management2000，26，1： | 1 |
| 12 | Trust, control, and risk in strategic alliances : An integrated framework 显示文摘 | Das T K Teng B S | 2001 | Organization Studies2001，22，2： | 1 |
| 13 | Stress-strain behavior of concrete in hybrid FRP-concrete-steel double-skin tu- bular columns 显示文摘 | YU T TENG J G WONG Y L | 2010 | Journal of Structural Engineering2010，136，4： | 1 |
| 14 | Intelligent controlled- wind-turbine emulator and induction-generator system using RBFN显示文摘 | Lin F J Teng L T Shieh P H | 2006 | IEEE Proceedings of Electric Power Applications2006，153，4： | 1 |
| 15 | The dynamics of alliance conditions in the alliance development process 显示文摘 | DAS T K Teng B S | 2002 | Journal of Management Studies2002，39，5： | 1 |
| 16 | Role of autophagy in angiogenesis in aortic endothelial cells显示文摘 | Du J Teng R J Guan T | 2012 | Am J Physiol Cell Physiol2012，302，2： | 1 |
| 17 | On the ballistic resistance of double-layered steel plates:An experimental and numerical investigation显示文摘 | Dey S Brvik T Teng X Wierzbicki T Hopperstad O S | 2007 | International Journal of Solids and Structures2007，44，： | 1 |
| 18 | Finite Element Modeling of Confined Concrete-I:Drucker-Prager Type Plasticity Model显示文摘 | Yu T Teng J G Wong Y L | 2010 | Engineering Structures2010，32，3： | 1 |
| 19 | Instabilities of strategic allian- ces: An internal tensions perspective显示文摘 | Das T K Teng B S | 2000 | Organization Science2000，11，1： | 1 |
| 20 | Managing Risks in Strategic Alliances 显示文摘 | Das T K Teng B S | 1999 | Academy of Management Executive1999，13，4： | 1 |
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