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| 1 | State-of-the-art review of soft computing applications in underground excavations显示文摘Soft computing techniques are becoming even more popular and particularly amenable to model the complex behaviors of most geotechnical engineering systems since they have demonstrated superior predictive capacity,compared to the traditional methods.This paper presents an overview of some soft computing techniques as well as their applications in underground excavations.A case study is adopted to compare the predictive performances of soft computing techniques including eXtreme Gradient Boosting(XGBoost),Multivariate Adaptive Regression Splines(MARS),Artificial Neural Networks(ANN),and Support Vector Machine(SVM) in estimating the maximum lateral wall deflection induced by braced excavation.This study also discusses the merits and the limitations of some soft computing techniques,compared with the conventional approaches available. | Wengang Zhang Runhong Zhang Chongzhi Wu Anthony Teck Chee Goh Suzanne Lacasse Zhongqiang Liu Hanlong Liu | 2020 | Geoscience Frontiers2020，11，4： | 33 |
| 2 | Emerging flexible and wearable physical sensing platforms for healthcare and biomedical applications显示文摘There are now numerous emerging flexible and wearable sensing technologies that can perform a myriad of physical and physiological measurements.Rapid advances in developing and implementing such sensors in the last several years have demonstrated the growing significance and potential utility of this unique class of sensing platforms.Applications include wearable consumer electronics,soft robotics,medical prosthetics,electronic skin,and health monitoring.In this review,we provide a state-ofthe-art overview of the emerging flexible and wearable sensing platforms for healthcare and biomedical applications.We first introduce the selection of flexible and stretchable materials and the fabrication of sensors based on these materials.We then compare the different solid-state and liquid-state physical sensing platforms and examine the mechanical deformation-based working mechanisms of these sensors.We also highlight some of the exciting applications of flexible and wearable physical sensors in emerging healthcare and biomedical applications,in particular for artificial electronic skins,physiological health monitoring and assessment,and therapeutic and drug delivery.Finally,we conclude this review by offering some insight into the challenges and opportunities facing this field. | Kenry Joo Chuan Yeo Chwee Teck Lim | 2016 | Microsystems & Nanoengineering2016，2，1： | 17 |
| 3 | Buttress plate fixation of coronoid process fractures via a medial approach显示文摘Purpose:To assess the clinical and radiographic outcomes of coronoid process fractures surgically managed with buttress plate fixation via a medial approach.Methods:A retrospective review of all coronoid fractures surgically fixed in our institution using a buttress plate technique via a medial approach between June 2012 and April 2015 by the senior author was performed.These fractures were all sizeable fractures contributing to persistent elbow instability in terrible triad or varus posteromedial rotatory instability injury patterns.A prospective telephone questionnaire was conducted to assess patient outcomes using the disabilities of the arm,shoulder and hand(DASH)score and Mayo hlbow performance score(MEPS).Results:Twelve patients were included in the study,comprising 10 males and 2 females with an average age of 39 years(range,19-72 years).Mean follow-up was 16 months(range.4-18 months).The average time to radiographic union was 4 months(range.3-7 months).Range of motion measurements at final follow-up were obtained in 11 out of 12 patients,with one patient defaulting follow-up.All 11 patients displayed a functional elbow range of motion of at least 30°-130°.with an average arc of motion of 130°(range.110°-140°).mean elbow flexion of 134°(range.110°-140°)and mean flexion contracture of 3°(range.0°-20°).The mean DASH score was 16(range.2.5-43.8)and the mean MEPS was 75(range.65-100).Complications observed included one patient with a superfic ial wound infection which resolved with a course of oral antibiotics and one patient with radiographic evidence of heterotopic ossification which was conservatively managed.No residual elbow instability was observed and no reoperations were performed.Conclusion:Buttress plate fixation via a medial approach of coronoid process fractures that contribute to persistent elbow instability represents a reliable method of treatment that produces satisfactory and predictable outcomes. | Kelvin Kah Ho Lor Dong Hao Toon Andy Teck Huat Wee | 2019 | Chinese Journal of Traumatology2019，22，5： | 9 |
| 4 | 人肺组织内源性显微荧光特性研究显示文摘采用新型显微荧光分光光度系统 ,实现激光诱导人肺组织内源性显微荧光光谱与图像的测量 ,获得不同组织层 (即上皮层 ,粘膜层和软骨层 )的荧光分布和荧光特性 ,为探索癌与正常组织自体荧光光谱特征差异的根源 。 | 郑蔚 黄志伟 谢树森 S.M.Krishnan Chia Teck Chee | 2001 | 中国激光2001，28，7： | 7 |
| 5 | Recurrent giant fibrovascular polyp of the esophagus显示文摘Giant fibrovascular polyps of the esophagus and hypopharynx are rare benign esophageal tumors. They arise most commonly in the upper esophagus and may, rarely, originate in the hypopharynx. They can vary significantly in size. Even though they are benign, they may be lethal due to either bleeding or, rarely, asphyxiation if a large polyp is regurgitated. Patients commonly present with dysphagia or hematemesis. The polyps may not be well visualized on endoscopy and imaging plays a vital role in aiding diagnosis as well as providing important information for preoperative planning, such as the location of the pedicle, the vascularity of the polyp and the tissue elements of the mass. They can also be recurrent in rare cases, especially if the resection margins of the base are involved. We review the recent literature and report a case of a 61-year-old man with a recurrent giant esophageal fibrovascular polyp with illustrative contrast barium swallow, CT and intra-operative images, who required several surgeries via a combination of endoscopic, trans-oral, trans-cervical, trans-thoracic and trans-abdominal approaches. | Ser Yee Lee Weng Hoong Chan Ranjiv Sivanandan Dennis Teck Hock Lim Wai Keong Wong | 2009 | World Journal of Gastroenterology2009，15，29： | 7 |
| 6 | Attenuation of rock blasting induced ground vibration in rock-soil interface显示文摘Blasting has been widely used in mining and construction industries for rock breaking.This paper presents the results of a series of field tests conducted to investigate the ground wave propagation through mixed geological media.The tests were conducted at a site in the northwestern part of Singapore composed of residual soil and granitic rock.The field test aims to provide measurement data to better understand the stress wave propagation in soil/rock and along their interface.Triaxial accelerometers were used for the free field vibration monitoring.The measured results are presented and discussed,and empirical formulae for predicting peak particle velocity (PPV) attenuation along the ground surface and in soil/rock were derived from the measured data.Also,the ground vibration attenuation across the soil-rock interface was carefully examined,and it was found that the PPV of ground vibration was decreased by 37.2% when it travels from rock to soil in the vertical direction. | Bhagya Jayasinghe Zhiye Zhao Anthony Goh Teck Chee Hongyuan Zhou Yilin Gui | 2019 | Journal of Rock Mechanics and Geotechnical Engineering2019，11，4： | 7 |
| 7 | A topologically substituted boron nitride hybrid aerogel for highly selective CO2 uptake显示文摘A topologically mediated synthesis of porous boron nitride aerogel has been experimentally and theoretically investigated for carbon dioxide (CO2)uptake. Replacement of the carbon atoms in a precursor aerogel of graphene oxide and carbon nanotubes was achieved using an elemental substitution reaction,to obtain a boron and nitrogen framework.The newly prepared BN aerogel possessed a specific surface area of 716.56m^2/g and exhibited an unprecedented twenty- fold increase in CO2uptake over N2,adsorbing 100cc/g at 273K and 80cc/g in ambient conditions,as verified by adsorption isotherms via the multipoint Brunauer-Emmett-Teller (BET)method.Density functional theory calculations were performed to give hints on the mechanism of such high selectivity of CO2 over N2adsorption in BN aerogel,which may be due to the interaction between the intrinsic polar nature of B-N bonds and the high quadrupole moment of CO2 over N2. | R.Govindan Kutty Sivaramapanicker Sreejith Xianghua Kong Haiyong He Hong Wang Junhao Lin Kazu Suenaga Chwee Teck Lim Yanli Zhao Wei Ji Zheng Liu | 2018 | Nano Research2018，11，12： | 5 |
| 8 | Comparative studies of versatile extracellular proteolytic activities of lactic acid bacteria and their potential for extracellular amino acid productions as feed supplements显示文摘Background:Increasing understanding on the functions of amino acids (AA) has led to new commercial applications and expansion of the worldwide markets.However,the current technologies rely heavily on non-food grade microorganism and chemical synthesis for the production of AA.Several studies reported that lactic acid bacteria (LAB) have the capability of producing AA owing to their well-established proteolytic system and amino acid biosynthesis genes.Hence,the objectives of this study were to explore the extracellular proteolytic activity of LAB isolated from various Malaysian fermented foods and their potential to produce AA extracellularly as feed supplements.Results:All the studied LAB isolates were versatile extracellular protease producers,whereby extracellular protease activities were detected from acidic to alkaline pH (pH 5,pH 6.5,pH 8) using qualitative and quantitative proteolytic assays.The highest proteolytic activity at pH 5 (15.76 U/mg) and pH 8 (19.42 U/mg) was achieved by Lactobacillus plantarum RG14,while Lactobacillus plantarum RS5 exhibited the highest proteolytic activity of 17.22 U/mg at pH 6.5.As for the results of AA production conducted in de Man,Rogosa and Sharpe medium and analysed by high pressure liquid chromatography system,all LAB isolates were capable of producing an array of AA.Generally,Pediococcus sp.showed greater ability for AA production as compared to Lactobacillus sp.Moreover,the studied LAB were able to produce a few major feed supplement AA such as methionine,lysine,threonine and tryptophan.P.pentosaceus TL-3 recorded the highest methionine and threonine productivity of 3.72 mg/L/h and 5.58 mg/L/h respectively.However,L.plantarum I-UL4 demonstrated a lysine productivity of 1.24 mg/L/h,while P.acidilactici TP-6 achieved up to 1.73 mg/L/h of tryptophan productivity.Conclusion:All the 17 studied LAB isolates possessed versatile extracellular proteolytic system and have vast capability of producing various amino acids including a few major feed supplement AA such as methionine,lysine,threonine and tryptophan.Despite AA production was strain dependent,the studied LAB isolates possessed vast potential and can be exploited further as a bio-agent or an alternative amino acids and bioactive peptide producers. | Ye Heng Lim Hooi Ling Foo Teck Chwen Loh Rosfarizan Mohamad Norhani Abdullah | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 5 |
| 9 | Cell biomechanics and its applications in human disease diagnosis显示文摘Certain diseases are known to cause changes in the physical and biomechanical properties of cells.These include cancer,malaria,and sickle cell anemia among others.Typically,such physical property changes can result in several fold increases or decreases in cell stiffness,which are significant and can result in severe pathology and eventual catastrophic breakdown of the bodily functions.While there are developed biochemical and biological assays to detect the onset or presence of diseases,there is always a need to develop more rapid,precise,and sensitive methods to detect and diagnose diseases.Biomechanical property changes can play a significant role in this regard.As such,research into disease biomechanics can not only give us an in-depth knowledge of the mechanisms underlying disease progression,but can also serve as a powerful tool for detection and diagnosis.This article provides some insights into opportunities for how significant changes in cellular mechanical properties during onset or progression of a disease can be utilized as useful means for detection and diagnosis.We will also showcase several technologies that have already been developed to perform such detection and diagnosis. | Yasaman Nematbakhsh Chwee Teck Lim | 2015 | Acta Mechanica Sinica2015，31，2： | 5 |
| 10 | Photon momentum transfer in inhomogeneous dielectric mixtures and induced tractor beams显示文摘The determination of optical force as a consequence of momentum transfer is inevitably subject to the use of the proper momentum density and stress tensor.It is imperative and valuable to consider the intrinsic scheme of photon momentum transfer,particularly when a particle is embedded in a complex dielectric environment.Typically,we consider a particle submerged in an inhomogeneous background composed of different dielectric materials,excluding coherent illumination or hydrodynamic effects.A ray-tracing method is adopted to capture the direct process of momentum transfer from the complex background medium,and this approach is validated using the modified Einstein–Laub method,which uses only the interior fields of the particle in the calculation.In this way,debates regarding the calculation of the force with different stress tensors using exterior fields can be avoided.Our suggested interpretation supports only the Minkowski approach for the optical momentum transfer to the embedded scatterer while rejecting Peierls’s and Abraham’s approaches,though the momentum of a stably moving photon in a continuous background medium should be considered to be of the Abraham type.Our interpretation also provides a novel method of realizing a tractor beam for the exertion of negative force that offers an alternative to the use of negative-index materials,optical gain,or highly non-paraxial or multiple-light interference. | Cheng-Wei Qiu Weiqiang Ding MRCMahdy Dongliang Gao Tianhang Zhang Fook Chiong Cheong Aristide Dogariu Zheng Wang Chwee Teck Lim | 2015 | Light(Science & Applications)2015，4，1： | 3 |
| 11 | Preface:molecular,cellular,and tissue mechanobiology显示文摘Mechanics plays a crucial role in a diversity of biological processes at different length (from molecules, cells, tissues,organs to organisms) and time scales. As a rapidly growing field across the interfaces of mechanics, biology, and medical engineering, mechanobiology aims to identify the mechanical and biological responses of cells and tissues of mechanical factors (e.g., stress, strain, and substrate stiffness) and their underlying mechanisms at different scales; to correlate the physiological and pathological growth, adaption, remodeling, and degradation of tissues and organs with their mechanical forces, properties, and environments; | Xi-Qiao Feng Peter Vee Sin Lee Chwee Teck Lim | 2017 | Acta Mechanica Sinica2017，33，2： | 3 |
| 12 | Rational Design and Application of an Indolium-Derived Heptamethine Cyanine with Record-Long Second Near-Infrared Emission显示文摘Heptamethine cyanine dyes,typified by indocyanine green,have been extensively employed as bioimaging indicators and theranostic agents.Significant efforts have been made to develop functional heptamethine cyanine dyes with outstanding bioimaging and theranostic utilities.In this work,we rationally designed and successfully developed a novel indolium-like heptamethine cyanine dye by installing indolium-derived polycyclic aromatic hydrocarbons on the terminal ends of a conjugated polyene backbone.This dye showed excellent photostability and showed bright fluorescent emission in the second near-infrared(NIR-Ⅱ)window with a peak at approximately 1120 nm.Such long wavelength emission prompted a superior bioimaging resolution in vivo.In particular,this NIR-Ⅱ dye had the remarkable capability of marking the blood vessels of the hindlimbs,abdomens,and brains of mice.More significantly,this dye involved a typical indolium-like heptamethine skeleton and exhibited two strong absorption bands in the 700–1300 nm NIR range,which endowed it with an intrinsic tumor-targeting capability and a high photothermal conversion efficiency(up to 68.2%),serving for the photothermal therapy of tumors under the guidance of NIR-Ⅱ fluorescence imaging.This work provides an efficient design strategy for achieving indolium-like heptamethine cyanine dyes with further NIR-Ⅱ emission. | Xiaoxie Ma Yurou Huang Syed Ali Abbas Abedi Heejeong Kim Tan Teck Boon Davin Xiaogang Liu Wen-Chao Yang Yao Sun Sheng Hua Liu Jun Yin Juyoung Yoon Guang-Fu Yang | 2022 | CCS Chemistry2022，4，6： | 2 |
| 13 | A learning-based model of repeated games with incomplete information显示文摘 | Juin-Kuan Chong Colin F. Camerer Teck H. Ho | 2005 | Games and Economic Behavior2005，，2： | 2 |
| 14 | Tumor Dissemination: An EMT Affair显示文摘 | Jean Paul Thiery Chwee Teck Lim | 2013 | Cancer Cell2013，，3： | 2 |
| 15 | Functional micro‐concrete 3D hybrid structures f abricated by two‐photon polymerization显示文摘Arbitrary micro-scale three-dimensional(3D)structures fabrication is a dream to achieve many exciting goals that have been pursued for a long time.Among all these applications,the direct 3D printing to fabricate human organs and integrated photonic circuits are extraordinary attractive as they can promote the current technology to a new level.Among all the 3D printing methods available,two-photon polymerization(2PP)is very competitive as it is the unique method to achieve sub-micron resolution to make any desired tiny structures.For the conventional 2PP,the building block is the photoresist.However,the requirement for the building block is different for different purposes.It is very necessary to investigate and improve the photoresist properties according to different requirements.In this paper,we presented one hybrid method to modify the mechanical strength and light trapping efficiency of the photoresist,which transfers the photoresist into the micro-concretes.The micro-concrete structure can achieve±22%strength modification via a silica nano-particles doping.The structures doped with gold nano-particles show tunable plasmonic absorption.Dye doped hybrid structure shows great potential to fabricate 3D micro-chip laser. | Yang Li Lianwei Chen Fang Kong Zuyong Wang Ming Dao Chwee Teck Lim Fengping Li Minghui Hong | 2017 | 光电工程2017，44，4： | 2 |
| 16 | Reliability analysis of geotechnical infrastructures: Introduction显示文摘In the design of geotechnical infrastructure,engineers have to deal with naturally occurring soils and rocks which are subjected to spatial variability as well as other uncertainties such as errors in measurement and in modeling methods.Reliability assessment which provides a systematic approach for quantifying the risk of failure has been shown to be a promising tool for solving these challenging geotechnical engineering problems.The method provides a more consistent measure of the level of safety or“structural reliability”through the evaluation of a reliability index and the associated“failure”probability,and is a method that satisfies the need to clearly convey safety issues to the public and regulatory authorities.Various methods for calculating the reliability of geotechnical infrastructures with regard to the assessment of the ultimate and serviceability limit states have been proposed by many researchers and these approaches include:the direct Monte Carlo Simulation,Bayesian and other sampling techniques,the first-order reliability method and the second-order reliability method,the random field method,the response surface method and other surrogate models with the related probabilistic procedures.In this special issue of Geoscience Frontiers,we assemble eleven invited papers which provide insights on the latest developments and challenges in applying probabilistic and reliability methods to geotechnical infrastructure design. | Wengang Zhang Anthony Teck Chee Goh | 2018 | Geoscience Frontiers2018，9，6： | 2 |
| 17 | The role of immunologic factors in the etiology of pregnancy-induced hypertension 显示文摘 | Teck T Wurfel W | 1995 | Zentralbl Gynakol1995，117，1： | 1 |
| 18 | A tolerancing optimization methodfor product design显示文摘 | Ngoi B K A Teck 0 C | 1997 | The International Journal of AdvancedManufacturing Technology1997，13，4： | 1 |
| 19 | Inband crosstalk analysis of optical cross-connect architecture显示文摘 | Teck Yoong Chai Tee Hiang Cheng | 2005 | IEEE J Lightwave Technol2005，23，2： | 1 |
| 20 | Crosstalk analysis for limitedwavelength-interchanging cross connects显示文摘 | Teck Yoong Chai Tee Hiang Cheng | 2002 | IEEE Photon Technol Lett2002，14，5： | 1 |
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