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| 1 | Effect of preoperative regional artery chemotherapy on proliferation and apoptosis of gastric carcinoma cells显示文摘AIM: To study the effects of preoperative regional arterychemotherapy (PRACT) in inducing growth inhibition andapoptosis of gastric carcinorna (GC) calls.METHODS: TUNEL ( terminal-deoxynucleotidyl-transferaseTdT-mediated dUTP-fluorescein and labeling) method andimmunohistochemical techniques were used to detect thestate of apoptosis and proliferation of GC cells inhistopathologic sections. A total of 110 cases of GC and 68cases of metastatic lymph node with or without PRACT wereadopted. Correlations between apoptosis index (Al),proliferation index (PI) and PRACT and prognosis wereanalysed.RESULTS: The apoptosis index (Al) was significantly higherin the PRACT group (12.5 ‰ + 4.33‰) than in the untreatedgroup (7. 1‰ + 3. 43 ‰, P < 0. 001 ), whereas theproliferation index (PI) in the PRACT group (33.8 % ± 8.8% ) was eignificantly lower than that in untreated group (43.6 % + 12.8 %, P<0.01). Both Al and PI were correlated tothe differentiation degree of GC in PRACT group, the Al inthe differentiated group was higher than that inundifferentiated group (P<0.001), but the PI was lower inthe differentiated group than that of the undifferentiatedgroup ( P < 0.01 ). The Al of GC cells in metastatic lymphnode was also significantly higher in the PRACT group (7.9‰+ 3.41‰) than in the untreated group (3.6 ‰ + 2.93 ‰,P < 0.01 ), though the PI of GC cells in metastatic lymphnodes in the PRACT group (17. 2 % + 6. 8 % ) wassignificantly lower than that in the untreated group (26.7 %+ 9. 3 %, P < 0. 01 ). The severity of histopathologicchanges was significantly higher in the PRACT group than inthe untreated group ( P < 0.05). In addition, postoperativesurveys demonstrated that the 5-year survival rate of GCpatients in the PRACT group was significantly higher than thatof patients in the untreated group (P<0.01).CONCLUSION: Preoperative regional artery chemotherapy(PRACT) showed inhibitory action on the growth of GC cellsmainly through inhibiting proliferation and inducing theapoptosis of tumor cells. PRACT can improve the prognosisof GC patients also. | Tao, HQ Zou, SC | 2002 | World Journal of Gastroenterology2002，8，3： | 49 |
| 2 | A clinical and long-term follow-up study of perioperative sequential triple therapy for gastric cancer显示文摘INTRODUCTIONAlthough the long-term postoperative survival rateof gastric cancer(GC) patients has been improvedsignificantly since the local dissection of lymph nodewas widely used in China,yet the low curativeresection rate and the high recurrence rate fromperitoneal and hepatic metastases hinder it fromfurther improvement.To alter the currentunsatisfactory status of GC treatment,a | Zou SC Qiu HS Zhang CW Tao HQ | 2000 | World Journal of Gastroenterology2000，6，2： | 18 |
| 3 | Papulonecrotic tuberculid-a rare skin manifestation in a patient with pulmonary tuberculosis显示文摘 | Chen SC Tao HY Tseng HH | 2000 | J Formos Med Assoc2000，99，： | 2 |
| 4 | CHD and its risk factors in the People's Republic of China 显示文摘 | Tao SC Huang ZD Wu XG | 1989 | Int J Epidemiol1989，18，1： | 1 |
| 5 | Mutiplex PCR for simultaneous detection of human carcinoma related viruses显示文摘 | Tao SC Zhang XE Liu H | | 0，，07： | 1 |
| 6 | The role of the mitochondrial oxidative stress in the cytotoxic effects of the green tea catechin, (-)-epigallocatechin-3-gallate, in oral cells 显示文摘 | Tao L Forester SC Lambert JD | 2014 | Molecular nutrition & Food Research2014，58，4： | 1 |
| 7 | Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers显示文摘 | Tao SC Li Y Zhou J Qian J | 2008 | Glycobiology2008，18，10： | 1 |
| 8 | Cyclosporine A enhances Th2 bias at the maternal-fetal interface in early human pregnan- cy with aid of the interaction between maternal and fetal ceils 显示文摘 | Piao HL Wang SC Tao Y | 2012 | PLoS 0ne2012，7，45： | 1 |
| 9 | CHD and its risk fac- tors in the People's Republic of China显示文摘 | Tao SC Huang ZD Wu XG | 1989 | Int J Epidemi- ol1989，13，31： | 1 |
| 10 | Proteomic analysis of multiple mycloma:current status and future perspectives显示文摘 | GE F BI LJ TAO SC | | 0，，1： | 1 |
| 11 | Ahernans of cardiac calcium cycling in a cluster of ryanodine receptors: a simulation study 显示文摘 | Tao T O'Neill SC Diaz ME | 2008 | Am J Physiol Heart Circ Physiol2008，295，2： | 1 |
| 12 | Detection of serum level of TSGF,CA242 and CA19 -9 in pancereatic cancer显示文摘 | Jiang XT Tao HQ Zou SC | 2004 | Hepatobiliary Pancereat Dis Int2004，3，3： | 1 |
| 13 | Lectin microarrays identify cell-specific and functionally significant cell surface gly- can markers显示文摘 | Tao SC Li Y Zhou J | 2008 | Glycobiology2008，18，10： | 1 |
| 14 | Protein chip fabrication by capture of nascent polypeptides显示文摘 | Tao SC Zhu H | 2006 | Nat Biotec:hnol2006，24，10： | 1 |
| 15 | Lectin microarrays iden- tify cell specific and functionally significant cell surface glycan markers显示文摘 | Tao SC Li Y Zhou J Qian J | 2008 | Glycobiology2008，18，10： | 1 |
| 16 | Protein chip fabrication by capture of nascent pol- ypeptides显示文摘 | Tao SC Zhu H | 2006 | Nat Biotechnol2006，24，10： | 1 |
| 17 | Mechanises ba which cytoplasmic cal- cium wave propagation and alterans are generated in cardiac artial myocytes lacking T-tubules-insights from a simulation study 显示文摘 | Li Q O' Nell SC Tao T | 2012 | Bio- phys J2012，102，7： | 1 |
| 18 | Lectin microarrays identify cell-specific and functionally significant cell surface glycan markers显示文摘 | Tao SC Li Y Zhou J | 2008 | Glycobiology2008，18，10： | 1 |
| 19 | CHD and its risk factors in the People' s Republic of China显示文摘 | Tao SC | 1989 | Int J Epidemiol1989，，18： | 1 |
| 20 | Measurement of effects of the Chinese herbal medicine higenamine on left ventricular function using a cardiac probe显示文摘 | Wagner HN Tao SC | 1983 | Eur J Nucl Med1983，8，6： | 1 |
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