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| 1 | Effect of preoperative regional artery chemotherapy on proliferation and apoptosis of gastric carcinoma cells显示文摘AIM: To study the effects of preoperative regional arterychemotherapy (PRACT) in inducing growth inhibition andapoptosis of gastric carcinorna (GC) calls.METHODS: TUNEL ( terminal-deoxynucleotidyl-transferaseTdT-mediated dUTP-fluorescein and labeling) method andimmunohistochemical techniques were used to detect thestate of apoptosis and proliferation of GC cells inhistopathologic sections. A total of 110 cases of GC and 68cases of metastatic lymph node with or without PRACT wereadopted. Correlations between apoptosis index (Al),proliferation index (PI) and PRACT and prognosis wereanalysed.RESULTS: The apoptosis index (Al) was significantly higherin the PRACT group (12.5 ‰ + 4.33‰) than in the untreatedgroup (7. 1‰ + 3. 43 ‰, P < 0. 001 ), whereas theproliferation index (PI) in the PRACT group (33.8 % ± 8.8% ) was eignificantly lower than that in untreated group (43.6 % + 12.8 %, P<0.01). Both Al and PI were correlated tothe differentiation degree of GC in PRACT group, the Al inthe differentiated group was higher than that inundifferentiated group (P<0.001), but the PI was lower inthe differentiated group than that of the undifferentiatedgroup ( P < 0.01 ). The Al of GC cells in metastatic lymphnode was also significantly higher in the PRACT group (7.9‰+ 3.41‰) than in the untreated group (3.6 ‰ + 2.93 ‰,P < 0.01 ), though the PI of GC cells in metastatic lymphnodes in the PRACT group (17. 2 % + 6. 8 % ) wassignificantly lower than that in the untreated group (26.7 %+ 9. 3 %, P < 0. 01 ). The severity of histopathologicchanges was significantly higher in the PRACT group than inthe untreated group ( P < 0.05). In addition, postoperativesurveys demonstrated that the 5-year survival rate of GCpatients in the PRACT group was significantly higher than thatof patients in the untreated group (P<0.01).CONCLUSION: Preoperative regional artery chemotherapy(PRACT) showed inhibitory action on the growth of GC cellsmainly through inhibiting proliferation and inducing theapoptosis of tumor cells. PRACT can improve the prognosisof GC patients also. | Tao, HQ Zou, SC | 2002 | World Journal of Gastroenterology2002，8，3： | 49 |
| 2 | A clinical and long-term follow-up study of perioperative sequential triple therapy for gastric cancer显示文摘INTRODUCTIONAlthough the long-term postoperative survival rateof gastric cancer(GC) patients has been improvedsignificantly since the local dissection of lymph nodewas widely used in China,yet the low curativeresection rate and the high recurrence rate fromperitoneal and hepatic metastases hinder it fromfurther improvement.To alter the currentunsatisfactory status of GC treatment,a | Zou SC Qiu HS Zhang CW Tao HQ | 2000 | World Journal of Gastroenterology2000，6，2： | 18 |
| 3 | The helical domains of the stem re- gion of dengue virus envelope protein are involved in both virus assembly and entry 显示文摘 | Lin SR Zou G Hsieh SC | 2011 | Journal Of Virology2011，85，10： | 1 |
| 4 | Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins显示文摘 | Zou H Li Q Lin SC | 2007 | FEBS Lett2007，581，2： | 1 |
| 5 | Photodegradation Performance of g-C3N4 Fabricated by Directly Heating Melamine显示文摘 | Yah SC Li ZS Zou ZG | 2009 | Langmuir2009，25，10： | 1 |
| 6 | Photodegradation of Rhodamine B and Methyl Orange over Boron-Doped g-C3N4 under Visible Light Irradiation显示文摘 | Yan SC Li ZS Zou ZG | 2010 | Langmuir2010，26，： | 1 |
| 7 | Detection of serum level of TSGF,CA242 and CA19 -9 in pancereatic cancer显示文摘 | Jiang XT Tao HQ Zou SC | 2004 | Hepatobiliary Pancereat Dis Int2004，3，3： | 1 |
| 8 | Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins显示文摘 | Zou H Li Q Lin SC Wu Z Han J Ye Z | 2007 | FEBS Lett2007，581，2： | 1 |
| 9 | Photodegradation performance ofg-C3 N4 fabricated by directly heating melamine 显示文摘 | Yan SC Li Z S Zou Z G | 2009 | Langmuir2009，25，10： | 1 |
| 10 | Angiographic features colaterals and infarct topography of symptomatic occlusive radiation vasculopathy: a case-referent study 显示文摘 | Zou WX Leung TW Yu SC | 2013 | Stroke2013，44，： | 1 |
| 11 | Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins 显示文摘 | Zou H Li Q Lin SC | 2007 | FEBS Lett2007，581，2： | 1 |
| 12 | Clinical significance of preoperative regional intra-arterial infusion chemotherapy for advanced gastric cancer显示文摘 | Zhang CW Zou SC Shi D | 1999 | World J Gastroenterol1999，3，： | 1 |
| 13 | The influence of medical abortion compared with surgical abortion on subsequent pregnancy outcome显示文摘 | Gan CP Zou Y Wu SC | 2008 | Int Gynecol Obstet2008，101，3： | 1 |
| 14 | Determination of selected antibiotics in the Victoria Harbour and the Pearl River,South China using highperformance liquid chromatography-electrospray ionization tandem mass spectrometry显示文摘 | Xu WH Zhang G Zou SC | | 0，，： | 1 |
| 15 | Angiographic features, collaterals, and infarct topography of symptomatic occlusive radiation vasculopathy: a case referent study 显示文摘 | Zou WX Leung TW Yu SC | 2013 | Stroke2013，44，2： | 1 |
| 16 | Differential requirement of MKK4 and MKK7 in JNK activation by distinct scaffold proteins 显示文摘 | Zou H Li Q Lin SC | 2007 | FEBS Lett2007，581，2： | 1 |
| 17 | Treatment of malignancy hydropericardium through percutaneous catheterization with pigtail tube infra-Xiphoid and cava chemotherapy 显示文摘 | Shan QJ Zou JG Cao KJ Chen ML | 2000 | Linchuang Neike Zazhi (J Clin Cardio China)2000，16，9： | 1 |
| 18 | Systemic tumor suppression by the proapoptotic gene bik显示文摘 | Zou Y Peng H Zhou B Wen Y Wang SC Tsai EM Hung MC | | 0，，： | 1 |
| 19 | Photodegradation of Rhodamine B and Methyl Orange over Boron-Doped g-C3N4 under Visible Light Irradiation显示文摘 | Yan SC Li ZS Zou ZG | 2010 | Langmuir2010，26，： | 1 |
| 20 | Angiographic features,collaterals, and infarct topography of symptomatic occlusiveradiation vasculopathy: a case-referent study 显示文摘 | Zou WX Leung TW Yu SC | 2013 | Stroke2013，44，2： | 1 |
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