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| 1 | Preparation and self-assembly of amphiphilic polymer with aggregation-induced emission characteristics显示文摘An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells. | QIN AnJun ZHANG Ya HAN Ning MEI Ju SUN JingZhi FAN WeiMin TANG Ben Zhong | 2012 | Science China Chemistry2012，55，5： | 16 |
| 2 | Feature Extraction and Identification in Distributed Optical-Fiber Vibration Sensing System for Oil Pipeline Safety Monitoring显示文摘察觉到的分布式的光纤维的颤动(DOVS ) 的高敏感系统基于阶段敏感光时间域反射计(-OTDR) 技术也在真实应用程序引进高讨厌的东西警报率(NAR ) 。在这份报纸,小浪分解(WD ) 和小浪包分解(WPD ) 的特征抽取方法比较地为三个典型现场测试信号被学习,并且一个人工的神经网络(ANN ) 为事件鉴定被造。比较结果证明 WPD 监视的油管道安全地为 DOVS 信号分析和鉴定比 WD 有点好表现。鉴定率能被改进直到 94.4% ,并且讨厌的东西警报率能有效地被控制为有小浪包精力分发特征的鉴定网络象 5.6% 一样低。 | Huijuan WU Ya QIAN Wei ZHANG Chenghao TANG | 2017 | Photonic Sensors2017，7，4： | 15 |
| 3 | Marginal Land-based Biomass Energy Production in China显示文摘Fast economic development in China has resulted in a significant increase in energy demand. Coal accounts for 70% of China's primary energy consumption and its combustion has caused many environmental and health problems. Energy security and environmental protection requirements are the main drivers for renewable energy development in China. Small farmland and food security make bioenergy derived from corn or sugarcane unacceptable to China: the focus should be on generating bioenergy from lignocellulosic feedstock sources. As China cannot afford biomass energy production from its croplands, marginal lands may play an important role in biomass energy production. Although on a small scale, marginal land has already been used for various purposes. It is estimated that some 45 million hm2 of marginal land could be brought into high potential biomass energy production. For the success of such an initiative, it will likely be necessary to develop multipurpose plants. A case study, carried out on marginal land in Ningnan County, Sichuan Province with per capita cropland of 0.07 ha, indicated that some 380 000 tons of dry biomass could be produced each year from annual pruning of mulberry trees. This study supports the feasibility of producing large quantities of biomass from marginal land sources. | Ya Tang Jia-Sui Xie Shu Geng | 2010 | Journal of Integrative Plant Biology2010，52，1： | 12 |
| 4 | Preparation of Pt/C Catalyst with Solid Phase Reaction Method显示文摘The Pt/C catalyst was prepared with solid phase reaction method (Pt/C(S)) for the first time. Its performances were compared with that prepared by the traditional liquid phase reaction method. The results demonstrate that the electrocatalytic activity of Pt/C catalyst with solid phase reaction method for methanol oxidation is higher than that with liquid phase reaction method. XRD and TEM measurements indicate that the Pt/C(S) possesses low crystalline extent and small particle size. | Ya Wen TANG Hui YANG Wei XING Tian Hong LU | 2002 | Chinese Chemical Letters2002，13，5： | 10 |
| 5 | Boosting electrocatalytic water splitting via metal-metalloid combined modulation in quaternary Ni-Fe-P-B amorphous compound显示文摘Design and synthesis of highly efficient and cost-effective bifunctional catalysts for hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)remain a big challenge.Herein,a quaternary amorphous nanocompound Ni-Fe-P-B has been synthesized by a facile,scalable co-reduction method.The Ni-Fe-P-B exhibits high electrocatalytic activity and outstanding durability for both HER and OER,delivering a current density of 10 mA·cm^-2 at overpotentials of 220 and 269 mV,respectively.When loaded on carbon fiber paper(CFP)as a bifunctional catalyst,the Ni-Fe-P-B@CFP electrode requires a low cell voltage of 1.58 V to obtain 10 mA·cm^-2 for overall water splitting with negligible recession over 60 h.The excellent catalytic performances of Ni-Fe-P-B mainly benefit from the metal-metalloid combined composition modulation and the unique amorphous structure.This work provides new insights into the design of robust bifunctional catalysts for water splitting,and may promote the development of multicomponent amorphous catalysts. | Wukui Tang Xiaofang Liu Ya Li Yanhui Pu Yao Lu Zhiming Song Qiang Wang Ronghai Yu Jianglan Shui | 2020 | Nano Research2020，13，2： | 8 |
| 6 | Structure of the Upper Mantle and Transition Zone Beneath the South China Block Imaged by Finite Frequency Tomography显示文摘We applied the finite frequency tomography method to S wave data recorded by 350 broadband stations beneath the South China Block(SCB) and its surroundings from earthquakes occurring between July 2007 and July 2010,to better understand upper mantle deformation.Differential travel-times in the pair of stations with appropriate weighting for each station are used in the inversion.Our results are consistent with previous tomography that show a high velocity anomaly beneath the Sichuan basin and a high velocity anomaly in the transition zone beneath the Yangtze Craton.However,the resolution of mantle heterogeneity provides new insight into the tectonic framework of subduction of Burmese lithosphere in the west part of the study region and subduction of oceanic lithosphere in the east.In the subduction realm,west of 107°E,a significant fast S-wave anomaly is located on the southeast of Sichuan Basin.East of 107°E,and two narrow and discontinuous fast S-wave anomalies occur at a depth of 400-600 km beneath the middle of the South China block overlain by the pronounced low S-wave anomalies at a depth of 100 and 400 km.If the fast anomalies located in the mantle transition zone represent stagnant slabs,their fragmented nature may suggest that they could be produced by different episodes of subduction beneath western Pacific island and the above slow velocity anomaly may associated with the back-arc regions of ongoing subduction.In addition,tomography also reveals an anomalously high S-wave velocity continental root extends eastward to a depth 400 km beneath the eastern Sichuan Basin.This anomaly may be related to eastern extrusion of Indian lithosphere associated with the collision of India and Eurasia.Moreover,our results also show large slow anomalies beneath the Red River fault region connected to deeper anomalies beneath the South China Fold Belt and South China Sea.AH these observations are consistent with the scenario that the South China block has been built by both of subduction of Paleopacific plate and eastward subduction of Burma microplate. | SUN Ya LIU Jianxin TANG Youcai CHEN Jiawei ZHOU Keping CHEN Bo | 2016 | Acta Geologica Sinica(English Edition)2016，90，5： | 8 |
| 7 | NGX6 inhibits AP-1 and Ets-1 expression and down-regulates cyclin D1 in human coloreetal cancer显示文摘Colorectal 癌症(CRC ) 是与病态和死亡的增加的发生被联系的一个普通恶意的肿瘤。鼻咽的联系癌的基因(NGX6 ) 6 是肿瘤转移的新奇候选人 suppressor 基因,它在 CRC 是下面调整的。在现在的学习,我们构造了 colorectal 织物 microarray 在 CRC 纸巾检验 NGX6, phospho-c-Jun N 终端 kinase (p-JNK ) ,和 phospho 细胞外的调整信号的 kinase (津贴) 的表示侧面。而 p-JNK 和津贴的表情在 CRC 纸巾是更高的,我们发现 NGX6 表示在 CRC 纸巾和变形淋巴节点是更低的,比在正常肠的 mucosa。NGX6, p-JNK,和津贴的表情与 colorectal 纸巾的临床的病理学的特征被联系。NGX6 overexpression 禁止了激活和 JNK1 的原子 translocation,它在细胞质导致了 p-JNK 的累积,但是没禁止激活和 ERK1/2 的原子 translocation。NGX6 也禁止了抄写因素 AP-1 (c-jun 和 c-fos ) 和 Ets-1 的表示。另外, NGX6 overexpression 减少了 cyclin D1 并且戏剧性地的表示压制了 cyclin D1 倡导者的 transcriptional 效率。我们建议那 NGX6 表情沉醉于人的 colorectal carcinogenesis 的多步过程。它的 overexpression 能禁止抄写因素的表示 AP-1 和 Ets-1,和下面调整在人的 CRC 的 cyclin D1 倡导者的 transcriptional 活动。 | Ya Peng Hongtao Li Minghua Wu Xiaoyan Wang Songqing Fan Fen Liu Bo Xiang Qin Guo Xueyuan Tang Shourong Shen | 2009 | Acta Biochimica et Biophysica Sinica2009，41，6： | 8 |
| 8 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 9 | Nitrogen Mineralization of Prunings of Six N_2-Fixing Hedgerow Species in a Dry Valley of the Jinsha River显示文摘A litterbag experiment of 12 weeks was conducted to study nitrogen mineralization process of prunings of six nitrogen-fixing hedgerow species in a dry valley of the Jinsha River. Prunings were incorporated into soil or used as mulch. The results indicated that pruning N of the six hedgerow species was mineralized fast in the first week and then decreased slowly in the rest of the study period. When prunings were incorporated into soil, the amount of nitrogen mineralized by the end of the first week accounted for 69.9%, 58.2%, 54.5%, 43.0%, 29.6% and 20.6% of the total N in prunings of Desmodium rensonii, Tephrosia Candida, Leucaena leucocephala, Albizia yunnanensis, Acacia dealbata, and Acacia mearnsii, respectively. When prunings of L. leucocephala were used as mulch materials, the amount of nitrogen mineralized in the first week was 16.2% less than that of prunings incorporated into soil. The mineralization pattern of pruning N could be simulated by an exponent model Nt% = N01% (1 ?exp(梜1t))+ No2% (1 ?exp(梜2t) where Nt% is cumulative mineralized N in time t, N01 % and No2 % are readily and less readily mineralizable N in prunings, respectively, and k1 and k2 are rate constants. A half-life period of pruning nitrogen mineralization could also be determined by this model. The nitrogen content in the pruning residues decreased quickly in the first week but fluctuated thereafter. The initial C/N ratio was negatively related to the mineralization rate of prunings. | SUN HUI, TANG YA and ZHAO QIGUO Institute of Soil Science, the Chinese Academy of Sciences, Nanjing, 210008 (China) Chengdu Institute of Biology, the Chinese Academy of Sciences, Chengdu 610041 (China) | 2002 | Pedosphere2002，12，1： | 7 |
| 10 | Antibacterial ability and cytocompatibility of Cu-incorporated Ni–Ti–O nanopores on NiTi alloy显示文摘Nearly equiatomic nickel–titanium(NiTi) alloy is an ideal implant biomaterial because of its shape memory effect, superelasticity, low elastic modulus as well as other desirable properties.However, it is prone to infection because of its poor antibacterial ability.The present work incorporated Cu into Ni–Ti–O nanopores(NP–Cu) anodically grown on the NiTi alloy to enhance its antibacterial ability, which was realized through electrodeposition.Our results show that incorporation of Cu(0.78 at%–2.37 at%)has little influence on the NP diameter, length and morphology.The release level of Cu ions is in line with loadage which may be responsible for the improved antibacterial ability of the NiTi alloy to combat possible bacterial infection in vivo.Meanwhile, the NP–Cu shows better cytocompatibility and even can promote proliferation of bone marrow mesenchymal stem cells(BMSCs),up-regulate collagen secretion and extracellular matrix mineralization when compared with Cu-free sample.Better antibacterial ability and cytocompatibility of the NP–Cu render them to be promising when serving as NiTi implant coatings. | Jia-Ming Zhang Yong-Hua Sun Ya Zhao Yan-Lian Liu Xiao-Hong Yao Bin Tang Rui-Qiang Hang | 2019 | Rare Metals2019，38，6： | 7 |
| 11 | Kiwifruit Genome Database(KGD):a comprehensive resource for kiwifruit genomics显示文摘Kiwifruit(Actinidia spp.)plants produce economically important fruits containing abundant,balanced phytonutrients with extraordinarily high vitamin C contents.Since the release of the first kiwifruit reference genome sequence in 2013,large volumes of genome and transcriptome data have been rapidly accumulated for a handful of kiwifruit species.To efficiently store,analyze,integrate,and disseminate these large-scale datasets to the research community,we constructed the Kiwifruit Genome Database(KGD;http://gffzz6fc08c45f9754a68hnu5x9x0ku5nb609c.ffgz.tsg.suse.edu.cn/).The database currently contains all publicly available genome and gene sequences,gene annotations,biochemical pathways,transcriptome profiles derived from public RNA-Seq datasets,and comparative genomic analysis results such as syntenic blocks and homologous gene pairs between different kiwifruit genome assemblies.A set of user-friendly query interfaces,analysis tools and visualization modules have been implemented in KGD to facilitate translational and applied research in kiwifruit,which include JBrowse,a popular genome browser,and the NCBI BLAST sequence search tool.Other notable tools developed within KGD include a genome synteny viewer and tools for differential gene expression analysis as well as gene ontology(GO)term and pathway enrichment analysis. | Junyang Yue Jiacheng Liu Wei Tang Ya Qing Wu Xiaofeng Tang Wei Li Ying Yang Lihuan Wang Shengxiong Huang Congbing Fang Kun Zhao Zhangjun Fei Yongsheng Liu Yi Zheng | 2020 | Horticulture Research2020，7，1： | 6 |
| 12 | Skeleton-vasculature chain reaction: a novel insight into the mystery of homeostasis显示文摘Angiogenesis and osteogenesis are coupled.However,the cellular and molecular regulation of these processes remains to be further investigated.Both tissues have recently been recognized as endocrine organs,which has stimulated research interest in the screening and functional identification of novel paracrine factors from both tissues.This review aims to elaborate on the novelty and significance of endocrine regulatory loops between bone and the vasculature.In addition,research progress related to the bone vasculature,vessel-related skeletal diseases,pathological conditions,and angiogenesis-targeted therapeutic strategies are also summarized.With respect to future perspectives,new techniques such as single-cell sequencing,which can be used to show the cellular diversity and plasticity of both tissues,are facilitating progress in this field.Moreover,extracellular vesicle-mediated nuclear acid communication deserves further investigation.In conclusion,a deeper understanding of the cellular and molecular regulation of angiogenesis and osteogenesis coupling may offer an opportunity to identify new therapeutic targets. | Ming Chen Yi Li Xiang Huang Ya Gu Shang Li Pengbin Yin Licheng Zhang Peifu Tang | 2021 | Bone Research2021，9，3： | 6 |
| 13 | Robustness and breakup of the spiral wave in a two-dimensional lattice network of neurons显示文摘The robustness and breakup of spiral wave in a two-dimensional lattice networks of neurons are investigated. The effect of small- world type connection is often simplified with local regular connection and the long-range connection with certain probability. The network effect on the development of spiral wave can be better described by local regular connection and changeable long-range connection probability than fixed long-range connection probability because the long-range probability could be changeable in realistic biological system. The effect from the changeable probability for long-range connection is simplified by multiplicative noise. At first, a stable rotating spiral wave is developed by using appropriate initial values, parameters and no-flux boundary conditions, and then the effect of networks is investigated. Extensive numerical studies show that spiral wave keeps its alive and robust when the intensity of multiplicative noise is below a certain threshold, otherwise, the breakup of spiral wave occurs. A statistical factor of synchronization in two-dimensional array is defined to study the phase transition of spiral wave by checking the membrane potentials of all neurons corresponding to the critical parameters(the intensity of noise or forcing current)in the curve for factor of synchronization. The Hindmarsh-Rose model is investigated, the Hodgkin-Huxley neuron model in the presence of the channel noise is also studied to check the model independence of our conclusions. And it is found that breakup of spiral wave is easier to be induced by the multiplicative noise in presence of channel noise. | MA Jun 1,2, TANG Jun 2 , ZHANG AiHua 3 & JIA Ya 2 1 Department of Physics, Lanzhou University of Technology, Lanzhou 730050, China 2 Department of Physics, Central China Normal University, Wuhan 430079, China 3 College of Electrical and Information Engineering, Lanzhou University of Technology, Lanzhou 730050, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，4： | 6 |
| 14 | Effect of platinum on the photocatalytic degradation of chlorinated organic compound显示文摘TiO 2 nanoparticles, doped with different Pt contents, were prepared by a modified photodeposition method using Degussa P-25 TiO 2 , H 2 PtCl 6 ·6H 2 O and methanol as the solvents. The physicochemical properties of Pt/TiO 2 were investigated by the nitrogen adsorption and desorption isotherm measurement technique, X-ray diffraction analysis and photoluminescence spectra, respectively. Reaction rates from photocatalytic removal of dichloromethane over Degussa P-25 TiO 2 and Pt/TiO 2 were evaluated. The average diameter and BET surface area of the TiO 2 catalyst particles were 300 nm and 50 m 2 /g, respectively. The degradation efficiency was 99.0%, 82.7%, 55.2%, and 57.9% with TiO 2 at inlet concentrations of 50, 100, 200, and 300 ppm, respectively. And the degradation efficiency was 99.3%, 79.7%, 76.5%, and 73.4% with a 0.005 wt.% Pt/TiO 2 at inlet concentrations of 50, 100, 200, and 300 ppm, respectively. In addition, we found that the photoluminescence emission peak intensities decreased with increases in the doping amount of Pt, which indicates that the irradiative recombination was weakened. Furthermore, the results showed that the UV/0.005 wt.% Pt/TiO 2 process was capable of efficiently decomposing gaseous DCM in air. | Chih Ming Ma Ya Wen Lee Gui Bing Hong Te Li Su Je Lueng Shie Chang Tang Chang | 2011 | Journal of Environmental Sciences2011，23，4： | 5 |
| 15 | A Late Quaternary Climate Record Based on Multi-Proxies Analysis from the Jiaochang Loess Section in the Eastern Tibetan Plateau,China显示文摘我们比较了稳定的碳从在东方西藏的高原的 Jiaochang 的黄土横断的同位素的记录,跨越最后 ~2 1,000 年,与多为成土作用,包括的磁性的危险性,泥土部分, Fe_d/Fe_t 比率,碳酸盐和总数代理数据器官的碳内容,为了探查δ^( 13 )的机制, C 在东方西藏的高原有机物和迟了的第四级的气候变化珍视。我们的结果显示在δ ^(13 ) 之间没有简单关系有机物和夏天季风变化的 C。在 C 有机物珍视的δ ^(13 ) 的变化(根据到 C_4 植物的 C_3 的比率) 从在温度,干旱和大气的 pCO_2 之中的相互作用的结果铺平。更干燥的气候和更低的大气的 pCO_2 水平贡献积极的碳同位素的旅行,当时同位素的旅行是的否定的碳更低的温度的结果和增加的大气的 pCO_2 水平。另外,我们的结果暗示西藏的季风可以在东方西藏高原在气候系统起一个重要作用,它明确地在那个区域反映经常变化的气候。结果在两个上提供新卓见进强迫的机制有机物和本地气候系统的δ ^(13 ) C 值。 | BAI Song TANG Ya WANG Chengshan HUANG Chengmin | 2007 | Acta Geologica Sinica(English Edition)2007，81，6： | 5 |
| 16 | The Role of ROS in Hydroquinone-induced Inhibition of K562 Cell Erythroid Differentiation显示文摘The role of ROS in hydroquinone-induced inhibition of K562 cell erythroid differentiation was investigated.After K562 cells were treated with hydroquinone for 24 h,and hemin was later added to induce erythroid differentiation for 48 h,hydroquinone inhibited hemin-induced | YU Chun Hong Suriguga LI Yang LI Yi Ran TANG Ke Ya JIANG Liang YI Zong Chun | 2014 | Biomedical and Environmental Sciences2014，27，3： | 5 |
| 17 | Cells in G_2/M phase increased in human nasopharyngeal carcinoma cell line by EBV-LMP1 through activation of NF-кB and AP-1显示文摘Although previous studies showed that the principal oncoprotein encoded by Epstein-Barr virus, latent membrane protein 1 (LMP1), could induce the nasopharyngeal carcinoma cells in G2/M phase increased, littleis known about the target molecules and mechanisms. The present study demonstrated that LMP1 couldinduce the accumulation of p53 protein and upregulate its transactivity in a dose dependent manner, whichresulted in the decrease of the kinase activity of cdc2/cyclin B complex and inducing arrest at G2/M phasethrough the activation of NF-kB and AP-1 signaling pathways, and the effect of NF-kB was more obviousthan that of AP-1. This study provided some significant evidence for further elucidating the molecular mechanisms that LMP1 had effects on the surveillance mechanism of cell cycle and promoting the survivalof transformed cells and tumorigenesis. | LIN DENG,JING YANG,XIAO RONG ZHAO,XI YUN DENG,LIANG ZENG,HUAN HUA GU,MIN TANG,YA CAOCancer Research Institute,Xiangya School of Medicine,Central South University,Xiangya Road 88,Chang-sha,Hunan 410078,China | 2003 | Cell Research2003，13，3： | 5 |
| 18 | Stable Carbon and Oxygen Isotopes of Pedogenic Carbonates in Ustic Vertisols: Implications for Paleoenvironmental Change显示文摘Pedogenic carbonates, found extensively in arid and semiarid regions, are important in revealing regional climatic and environmental changes as well as the carbon cycle. In addition, stable carbon and oxygen isotopic compositions of pedogenic carbonates have been used to rebuild paleoecology (biomass and vegetation) and to estimate paleotemperature and paleoprecipitation during past geological time. By utilizing the stable carbon and oxygen isotopic compositions (δ13C and (δ18O) of secondary nodules in Ustic Vertisols, this study looked into the climatic and environmental changes in the dry valleys of the Yuanmou Basin, Yunnan Province, in southwestern China. The results showed that during the early Holocene, a warm-humid or hot-humid climate existed in the Yuanmou Basin, but since then fluctuations in climate have occurred, with a dry climate prevailing. A highly significant correlation (r = 0.92, n = 9) between δ13C and δ18O values of carbonates illustrated that there had been a continual shifting between cold-humid and warm-dry climates in southwestern China including the Yuanmou Basin since the early Holocene. | HUANG Cheng-Min WANG Cheng-Shan TANG Ya | 2005 | Pedosphere2005，15，4： | 4 |
| 19 | The landscape of aging显示文摘Aging is characterized by a progressive deterioration of physiological integrity,leading to impaired functional ability and ultimately increased susceptibility to death.It is a major risk factor for chronic human diseases,including cardiovascular disease,diabetes,neurological degeneration,and cancer.Therefore,the growing emphasis on “healthy aging” raises a series of important questions in life and social sciences.In recent years,there has been unprecedented progress in aging research,particularly the discovery that the rate of aging is at least partly controlled by evolutionarily conserved genetic pathways and biological processes.In an attempt to bring full-fledged understanding to both the aging process and age-associated diseases,we review the descriptive,conceptual,and interventive aspects of the landscape of aging composed of a number of layers at the cellular,tissue,organ,organ system,and organismal levels. | Yusheng Cai Wei Song Jiaming Li Ying Jing Chuqian Liang Liyuan Zhang Xia Zhang Wenhui Zhang Beibei Liu Yongpan An Jingyi Li Baixue Tang Siyu Pei Xueying Wu Yuxuan Liu Cheng-Le Zhuang Yilin Ying Xuefeng Dou Yu Chen Fu-Hui Xiao Dingfeng Li Ruici Yang Ya Zhao Yang Wang Lihui Wang Yujing Li Shuai Ma Si Wang Xiaoyuan Song Jie Ren Liang Zhang Jun Wang Weiqi Zhang Zhengwei Xie Jing Qu Jianwei Wang Yichuan Xiao Ye Tian Gelin Wang Ping Hu Jing Ye Yu Sun Zhiyong Mao Qing-Peng Kong Qiang Liu Weiguo Zou Xiao-Li Tian Zhi-Xiong Xiao Yong Liu Jun-Ping Liu Moshi Song Jing-Dong J.Han Guang-Hui Liu | 2022 | Science China(Life Sciences)2022，65，12： | 4 |
| 20 | Effects of Low Concentrations of Di-(2-ethylhexyl) and Mono-(2-ethylhexyl) Phthalate on Steroidogenesis Pathways and Apoptosis in the Murine Leydig Tumor Cell Line MLTC-1显示文摘这研究的目的是在 vitro 在一根鼠科的 Leydig 肿瘤房间线(MLTC-1 ) 在 steroidogenesis 上评估 DEHP 和 MEHP 的低集中的效果。流动 cytometry 分析的结果表明 apoptotic 房间的比例显著地在暴露以后被增加到 DEHP。所有三基因(P450scc, P450c17,并且 3 ? HSD ) 在学习下面显示出增加的表达式追随者暴露到 DEHP 或 MEHP,尽管一些不足道的禁止的效果出现了在 10 ? mol/L 处理组同样与控制相比。它也被发现那 DEHP 或 MEHP 在特别刺激了 INSL3 mRNA 和蛋白质 0.001 ? mol/L 处理组。睾丸激素分泌物在暴露以后被刺激到 DEHP 或 MEHP。在 MLTC-1 房间的 steroidogenic 酶和 INSL3 的改变可能在雄激素生产上涉及 DEHP/MEHP 的 biphasic 效果。 | CHEN Xi LIU Ya Nan ZHOU Qing Hong LENG Ling CHANG Ying TANG Nai Jun | 2013 | Biomedical and Environmental Sciences2013，26，12： | 4 |
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