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| 1 | Interferon-Gamma Release Assay is Not Appropriate for the Diagnosis of Active Tuberculosis in High-Burden Tuberculosis Settings: A Retrospective Multicenter Investigation显示文摘 | Wan-Li Kang Gui-Rong Wang Mei-Ying Wu Kun-Yun Yang Er-Tai A Shu-Cai Wu Shu-Jun Geng Zhi-Hui Li Ming-Wu Li Liang Li Shen-Jie Tang | 2018 | Chinese Medical Journal2018，，3： | 30 |
| 2 | A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy显示文摘anti-CTLA-4 抗体由阻止 B7-CTLA-4 相互作用接近否定发信号引起肿瘤拒绝,这被假定。在比临床上有效的 dosing 完成的血浆层次更加高的集中,令人惊讶地, anti-CTLA-4 抗体 Ipilimumab 不由 CTLA-4 也不 CTLA-4 绑定堵住任何一 B7 trans-endocytosis 到使不能调动或联系房间的 B7。因而, Ipilimumab 不从人性化的任何一个 CTLA4 基因在树枝状的房间(DC ) 上增加 B7 (Ctla4 h/h ) 或人的 CD34 + 茎重新组成房间的 NSG 老鼠。在 Ctla4 高效地表示人和老鼠 CTLA4 基因,绑在人的 anti-CTLA-4 抗体然而并非老鼠 CTLA-4 的 h/m 老鼠导致 Treg 弄空和 Fc 受体依赖者肿瘤拒绝。堵住的抗体 L3D10 比得上在引起肿瘤拒绝的非阻塞的 Ipilimumab。显著地,输在人类化期间堵住活动的 L3D10 子孙在导致 Treg 弄空和肿瘤拒绝仍然保持充分能干。有效地在淋巴的器官堵住 CD4 T 细胞激活和 de novo CD8 T 细胞 priming 的 Anti-B7 抗体否定地不影响 Ipilimumab 的 immunotherapeutic 效果。因此,临床上有效的 anti-CTLA-4 mAb 由独立于检查点封锁的机制引起肿瘤拒绝但是依赖于主人 Fc 受体。我们为 CTLA-4 检查点的一个重评价的数据电话封锁假设并且为安全、有效的 anti-CTLA-4 mAbs 的下一代提供新卓见。 | Xuexiang Du Fei Tang Mingyue Liu Juanjuan Su Yan Zhang Wei Wu Martin Devenport Christopher A Lazarski Peng Zhang Xu Wang Peiying Ye Changyu Wang Eugene Hwang Tinghui Zhu Ting Xu Pan Zheng Yang Liu | 2018 | Cell Research2018，28，4： | 25 |
| 3 | Daclatasvir plus asunaprevir in treatment-na?ve patients with hepatitis C virus genotype 1b infection显示文摘AIM To assess daclatasvir plus asunaprevir(d UAL) in treatment-na?ve patients from China's Mainland, Russia and South Korea with hepatitis C virus(HCV) genotype 1 b infection. METHODS Patients were randomly assigned(3:1) to receive 24 wk of treatment with d UAL(daclatasvir 60 mg once daily and asunaprevir 100 mg twice daily) beginning on day 1 of the treatment period(immediate treatment arm) or following 12 wk of matching placebo(placebodeferred treatment arm). The primary endpoint was a comparison of sustained virologic response at posttreatment week 12(SVR12) compared with the historical SVR rate for peg-interferon plus ribavirin(70%) among patients in the immediate treatment arm. The first 12 wk of the study were blinded. Safety was assessed in d UAL-treated patients compared with placebo patients during the first 12 wk(doubleblind phase), and during 24 wk of d UAL in both arms combined.RESULTS In total, 207 patients were randomly assigned to immediate(n = 155) or placebo-deferred(n = 52) treatment. Most patients were Asian(86%), female(59%) and aged < 65 years(90%). Among them, 13% had cirrhosis, 32% had IL28 B non-CC genotypes and 53% had baseline HCV RNA levels of ≥ 6 million IU/m L. Among patients in the immediate treatment arm, SVR12 was achieved by 92%(95% confidence interval: 87.2-96.0), which was significantly higher than the historical comparator rate(70%). SVR12 was largely unaffected by cirrhosis(89%), age ≥ 65 years(92%), male sex(90%), baseline HCV RNA ≥ 6 million(89%) or IL28 B non-CC genotypes(96%), although SVR12 was higher among patients without(96%) than among those with(53%) baseline NS5 A resistanceassociated polymorphisms(at L31 or Y93 H). during the double-blind phase, aminotransferase elevations were more common among placebo recipients than among patients receiving d UAL. during 24 wk of d UAL therapy(combined arms), the most common adverse events(≥ 10%) were elevated alanine aminotransferase and upper respiratory tract infection; emergent grade 3-4 laboratory abnormalities were infrequently observed, and all grade 3-4 aminotransferase abnormalities(alanine aminotransferase, n = 9; aspartate transaminase, n = 6) reversed within 8-11 d. Two patients discontinued d UAL treatment; one due to aminotransferase elevations, nausea, and jaundice and the other due to a fatal adverse event unrelated to treatment. There were no treatment-related deaths.CONCLUSION d UAL was well-tolerated during this phase 3 study, and SVR12 with d UAL treatment(92%) exceeded thehistorical SVR rate for peg-interferon plus ribavirin of 70%. | Lai Wei Fu-Sheng Wang Ming-Xiang Zhang Ji-Dong Jia Alexey A Yakovlev Wen Xie Eduard Burnevich Jun-Qi Niu Yong Jin Jung Xiang-Jun Jiang Min Xu Xin-Yue Chen Qing Xie Jun Li Jin-Lin Hou Hong Tang Xiao-guang Dou Yash Gandhi Wen-Hua Hu Fiona McPhee Stephanie Noviello Michelle Treitel Ling Mo Jun Deng | 2018 | World Journal of Gastroenterology2018，24，12： | 17 |
| 4 | Motion behavior of particles in air-solid magnetically stabilized fluidized beds for separation显示文摘In order to study the settling mechanism of particles in an air-solid magnetically stabilized fluidized bed(MSFB) for separation,we carried out free settling and quasi-zero settling tests on the tracing particles.The results show that the main resistance forces as the tracing particles settled in an air-solid MSFB were motion resistance force and yield force.The motion resistance and yield forces greatly hindered the free settling of the particles by greatly decreasing the acceleration for settling process of the particles.The acceleration decreased from 3022.62 cm/s 2 to zero in 0.1 s,and in the end,the particles stopped in the air-solid MSFB.The yield force on particles increased with increasing the magnetic field intensity,resulting in decrease of the quasi-zero settling displacement.However,the yield force on particles decreased with increasing the fluidized air velocity,leading to increase of the quasi-zero settling displacement.When the structure and operating parameters of the air-solid MSFB were set up,the yield stress on particles stopped in an air-solid MSFB was a function of diameter and density of particles.The settling displacements of equal diameter particles increased with increasing their densities,and the settling displacements of equal density particles increased with increasing their diameters. | Song Shulei a,,Zhao Yuemin a,Luo Zhenfu a,Tang Ligang b a School of Chemical Engineering and Technology,China University of Mining & Technology,Xuzhou 221116,China b Coal Mining and Designing Department,Tiandi Science & Technology Company Co.Ltd.,Beijing 100013,China | 2012 | International Journal of Mining Science and Technology2012，22，5： | 13 |
| 5 | Covalently closed-circular hepatitis B virus DNA reduction with entecavir or lamivudine显示文摘AIM: To investigate the reduction in hepatitis B virus(HBV) covalently closed-circular DNA(ccc DNA) with entecavir(ETV) or lamivudine(LAM). METHODS: This analysis included patients who had participated in the randomized Phase Ⅲ study ETV-022 comparing ETV vs LAM in nucleos(t)ide-naive, HBe Agpositive patients. Patients received ETV(0.5 mg daily) or LAM(100 mg daily) for a minimum of 52 wk. Patients were eligible to participate in this sub-study if they had paired biopsies at baseline and week 48 with evaluable measurements for hepatic HBV ccc DNA and total hepatic HBV DNA. The main objective was to compare changes in hepatic HBV ccc DNA and total hepatic HBV DNA at week 48 of ETV or LAM treatment, which was a secondary endpoint of study ETV-022. Additional post hoc analyses included linear regression analyses to assess associations of baseline levels and on-treatment changes of ccc DNA with other baseline factors [sex,age, serum HBV DNA, alanine aminotransferase(ALT), Knodell necroinflammatory score, Ishak fibrosis score, total hepatic HBV DNA, and HBV genotype], or ontreatment factors(changes from baseline at week 48 in serum HBV DNA, ALT, Knodell necroinflammatory score, Ishak fibrosis score, total hepatic HBV DNA, and HBe Ag loss at week 48).RESULTS: Overall, 305 patients(ETV = 159; LAM = 146) of ETV-022 had paired baseline and week 48 liver biopsies with evaluable measurements for hepatic HBV ccc DNA and total hepatic HBV DNA, and were included in this analysis. Baseline demographics and disease characteristics were comparable between the two arms. After 48 wk, ETV resulted in significantly greater reductions in hepatic HBV ccc DNA [-0.9 log10 copies/human genome equivalent(HGEq) vs-0.7 log10 copies/HGEq; P = 0.0033] and total hepatic DNA levels(-2.1 log10 copies/HGEq vs-1.6 log10 copies/HGEq; P < 0.0001) than LAM. Virologic, biochemical, and histologic response rates at week 48 were also greater with ETV than with LAM. Baseline HBV ccc DNA levels were positively associated with baseline levels of serum HBV DNA and total hepatic HBV DNA, and negatively associated with HBV genotype F. On-treatment changes in HBV ccc DNA levels were negatively associated with baseline levels of serum HBV DNA and baseline ALT, and were positively associated with on-treatment changes in the levels of serum HBV DNA, total hepatic HBV DNA levels, and ALT, change in Knodell necroinflammatory score, and HBe Ag loss.CONCLUSION: Forty-eight weeks of ETV resulted in greater reductions in ccc DNA and total hepatic HBV DNA than LAM, but long-term therapy may be needed for ccc DNA elimination. | Scott Bowden Stephen Locarnini Ting-Tsung Chang You-Chen Chao Kwang-Hyub Han Robert G Gish Robert A de Man Miao Yu Cyril Llamoso Hong Tang | 2015 | World Journal of Gastroenterology2015，21，15： | 11 |
| 6 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 7 | Microstructures and mechanical properties of C-Mn-Cr-Nb and C-Mn-Si-Nb ultra-high strength dual-phase steels显示文摘The microstructures and mechanical properties of C-Mn-Cr-Nb and C-Mn-Si-Nb ultra-high strength dual-phase steels were studied by scanning electron microscopy(SEM),transmission electron microscopy(TEM),and tensile test.The results show that Si can promote the transformation of austenite(γ) to ferrite(α),enlarge the(α+γ) region,and increase the aging stability of martensite by inhibiting carbide precipitation.Adding Cr leads to the formation of retained austenite and martensiteaustenite(MA) constituents,as well as the decomposition of martensite during the overaging stage.Both of the steels show higher initial strain-hardening rates and two-stage strain-hardening characteristics.The C-Mn-Si-Nb steel shows the higher strain-hardening rate than the C-Mn-Cr-Nb steel in the first stage;however,there is no significant difference in the second stage.Although the tensile strength and elongation of the two steels both exceed 1000 MPa and 15%,respectively,the comprehensive mechanical properties of the C-Mn-Si-Nb steel are superior. | Zhi-gang Wang A i-min Zhao Zheng-zhi Zhao Jie-yun Ye Di Tang Guo-sen Zhu | 2012 | International Journal of Minerals,Metallurgy and Materials2012，19，10： | 7 |
| 8 | Nuclear domain 10 of the viral aspect显示文摘Nuclear domain 10(ND10) are spherical bodies distributed throughout the nucleoplasm and measuring around 0.2-1.0 μm. First observed under an electron microscope, they were originally described as dense bodies found in the nucleus. They are known by a number of other names, including Promyelocytic Leukemia bodies(PML bodies), Kremer bodies, and PML oncogenic domains. ND10 are frequently associated with Cajal bodies and cleavage bodies. It has been suggested that they play a role in regulating gene transcription. ND10 were originally characterized using human autoantisera, which recognizes Speckled Protein of 100 kD a, from patients with primary biliary cirrhosis. At the immunohistochemical level, ND10 appear as nuclear punctate structures, with 10 indicating the approximate number of dots per nucleus observed. ND10 do not colocalize with kinetochores, centromeres, sites of mR NA processing, or chromosomes. Resistance of ND10 antigens to nuclease digestion and salt extraction suggest that ND10 are associated with the nuclear matrix.They are often identified by immunofluorescent assay using specific antibodies against PML, Death domainassociated protein, nuclear dot protein(NDP55), and so on. The role of ND10 has long been the subject of investigation, with the specific connection of ND10 and viral infection having been a particular focus for almost 20 years. This review summarizes the relationship of ND10 and viral infection. Some future study directions are also discussed. | Yisel A Rivera-Molina Francisco Puerta Martínez Qiyi Tang | 2013 | World Journal of Virology2013，2，3： | 7 |
| 9 | Effective Hybrid Teaching-learning-based Optimization Algorithm for Balancing Two-sided Assembly Lines with Multiple Constraints显示文摘Due to the NP-hardness of the two-sided assembly line balancing(TALB) problem, multiple constraints existing in real applications are less studied, especially when one task is involved with several constraints. In this paper, an effective hybrid algorithm is proposed to address the TALB problem with multiple constraints(TALB-MC). Considering the discrete attribute of TALB-MC and the continuous attribute of the standard teaching-learning-based optimization(TLBO) algorithm, the random-keys method is hired in task permutation representation, for the purpose of bridging the gap between them. Subsequently, a special mechanism for handling multiple constraints is developed. In the mechanism, the directions constraint of each task is ensured by the direction check and adjustment. The zoning constraints and the synchronism constraints are satisfied by teasing out the hidden correlations among constraints. The positional constraint is allowed to be violated to some extent in decoding and punished in cost function. Finally, with the TLBO seeking for the global optimum, the variable neighborhood search(VNS) is further hybridized to extend the local search space. The experimental results show that the proposed hybrid algorithm outperforms the late acceptance hill-climbing algorithm(LAHC) for TALB-MC in most cases, especially for large-size problems with multiple constraints, and demonstrates well balance between the exploration and the exploitation. This research proposes an effective and efficient algorithm for solving TALB-MC problem by hybridizing the TLBO and VNS. | TANG Qiuhua LI Zixiang ZHANG Liping FLOUDAS C A CAO Xiaojun | 2015 | Chinese Journal of Mechanical Engineering2015，28，5： | 7 |
| 10 | ISSR Analysis on Genetic Diversity of the 34 Populations of Oryza meyeriana Distributing in Yunnan Province,China显示文摘The genetic diversity of the 34 populations of wild rice Oryza meyeriana Baill. distributed in Yunnan Province, China was analyzed using 13 inter-simple sequence repeat (ISSR) markers. A total of 168 bands were amplified, of which 135 polymorphic bands were discovered and the percentage of polymorphic bands (PPB) was 80.36%. A genetic diversity was revealed as Nei's gene diversity (H) = 0.2666 and Shannon information index (I) = 0.4028 at population level. The 34 populations were divided into different groups based on administrative regions, latitude and longitudes, river areas, altitudes of their origins, and their indexes such as Na (number of alleles), Ne (effective number of alleles), H, I and PPB were calculated. Richer genetic diversity was found in the wild rice populations distributed in Simao Prefecture than that in Lingcang Prefecture or Xishuangbanna Prefecture whereas the least genetic diversity was in Baoshan Prefecture or Dehong Prefecture. Rich genetic diversity was also discovered in the wild rice populations originated from higher than 710 m altitude around the middle and lower reaches of the Lancang River belonging to the Pacific Ocean drainage system. The 34 populations could be classified into two groups, one group covered the wild rice distributing in Simao Prefecture only while the other group covered ones in Lingcang, Xishuangbanna and Dehong Prefectures. The issue on how to effectively conserve the wild rice germplasm was discussed. | WAN Ya-tao A Xin-xiang FAN Chuan-zhang Xu Fu-rong YU Teng-qiong TANG Cui-feng DAI Lu-yuan | 2008 | Rice science2008，15，1： | 6 |
| 11 | Age and menopausal status are important factors influencing the serum human epididymis secretory protein 4 level:a prospective cross-sectional study in healthy Chinese people显示文摘Background::Human epididymis secretory protein 4(HE4)is a new ovarian cancer biomarker.The factors influencing HE4 levels are not clear,and the reference data in China are limited.Here,we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chinese people.Methods::A total of 2493 healthy females aged 40 years or older were recruited from March 2013 to March 2017 with the cooperation of four medical institutions across Beijing,China.The serum levels of HE4 and cancer antigen 125(CA125)were measured by enzyme-linked immunosorbent assay.The Wilcoxon rank-sum test of variance and a stratified analysis were used to analyze the relationships among age,menopausal status,and levels of HE4 or CA125.Confidence intervals(5%-95%)were determined for reference ranges in different populations.Results::There was a statistically significant difference in median HE4 levels between the post-menopausal(n=2168)and premenopausal groups(n=325)(36.46 vs.24.04 pmol/L,Z=-14.41,P<0.001).HE4 increased significantly with age in the post-menopausal groups(H=408.18,P<0.001)but not in the pre-menopausal subjects(Z=-0.43,P=0.67).The upper 95th percentile of HE4 levels were 44.63 pmol/L for pre-menopausal women,78.17 pmol/L for post-menopausal women,and 73.3 pmol/L for all women.In the post-menopausal population,the HE4 reference ranges were 13.15 to 47.31,14.31 to 58.04,17.06 to 73.51,24.50 to 115.25,and 35.71 to 212.37 pmol/L for different age groups from forty divided by decade.The CA125 level was affected mainly by menopausal status and not age.Conclusions::Menopausal status and age were both important factors influencing the level of HE4,and age affected HE4 levels mainly in post-menopausal women.The HE4 level was higher in the post-menopausal population than in the pre-menopausal population and increased with age. | Hong-Yan Cheng Lin Zeng Xue Ye Rui-Qiong M a Zhi-Jian Tang Hong-Ling Chu Yi-M ing Zhao Li-Rong Zhu Yu-Nong Gao Xiao-Hong Chang Heng Cui | 2020 | Chinese Medical Journal2020，，11： | 6 |
| 12 | Effects of vegetation cover on recruitment of Ulmus pumila L. in Horqin Sandy Land, northeastern China显示文摘Understanding the effects of vegetation cover on seedling survival is helpful for promoting vegetation restoration in environmentally fragile zones. This study was conducted in the desertified, moving sand dunes of Horqin Sandy Land, Inner Mongolia, northeastern China. We hyphothesized that(1) seed density(i.e., number/m2) increases as vegetation cover increases, and(2) there will be more surviving seedlings in locations with higher vegetation covers. Total vegetation cover and initial densities of seeds, germinated seeds and surviving seedlings of Ulmus pumilia were evaluated under various vegetation covers in trying to clarify the effects of vegetation cover on the early stages of the plant life history. In agreement with the first hypothesis, initial seed densities were greater(P<0.05) under higher vegetation covers. The relationship between vegetation cover and initial seed density was represented by a quadratic regression, where a threshold occurred with a vegetation cover of 36%(P<0.05). The higher total vegetation covers, however, did not result in increased densities of germinated seeds(P>0.05), which on average represented 16.7% of initial seed densities. Even more, three months after the study initiation, total vegetation covers were similar(P>0.05) at all positions in the dunes, and they determined a similar number(P>0.05) of surviving seedlings at those positions(i.e. the second hypothesis had to be rejected). The mean number of seed- lings that survived at all positions was only 4.5% of germinated seeds. The number of surviving elm seedlings(0 to 1.7 seedlings/m2) under various vegetations covers(12.2% to 20.8%) at all dune positions by late summer would most likely not contribute to vegetation restoration in the study area. | DeMing JIANG Yi TANG Carlos A BUSSO | 2014 | Journal of Arid Land2014，6，3： | 5 |
| 13 | 超重和正常体质量患者的心力衰竭新发率的荟萃分析显示文摘肥胖和新发心力衰竭之间的关系已经反复确立,关于超重与心力衰竭发展风险知之甚少。该系统回顾和荟萃分析旨在探讨超重、肥胖与新发心力衰竭发生率的关系。在该研究中,研究者从数据库创建开始到2017年6月,系统检索了MEDLINE,Medline InProcess and Other Non-Indexed Citations,EMBASE,Scopus和Cochrane对照试验中心登记册。 | Krittanawong C Tunhasiriwet A Wang Z Zhang H Prokop LJ Chirapongsathorn S Sun T Kitai T Tang WHW 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，4： | 4 |
| 14 | Organic electroluminescent diodes显示文摘 | Tang C W VanSlyke S A | | 0，，： | 3 |
| 15 | Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation显示文摘Splenomegaly is a well-known phenomenon typically associated with inflammation.However,the underlying cause of this phenotype has not been well characterized.Furthermore,the splenomegaly phenotype seen in lymphotoxin(LT)signaling-deficient mice is characterized by increased numbers of splenocytes and splenic neutrophils.Splenomegaly,as well as the related phenotype of increased lymphocyte counts in non-lymphoid tissues,is thought to result from the absence of secondary lymphoid tissues in LT-deficient mice.We now present evidence that mice deficient in LTα1β2 or LTβR develop splenomegaly and increased numbers of lymphocytes in non-lymphoid tissues in a microbiota-dependent manner.Antibiotic administration to LTα1β2-or LTβR-deficient mice reduces splenomegaly.Furthermore,re-derived germ-free Ltbr−/−mice do not exhibit splenomegaly or increased inflammation in non-lymphoid tissues compared to specific pathogen-free Ltbr−/−mice.By using various LTβ-and LTβR-conditional knockout mice,we demonstrate that retinoic acid-related orphan receptorγT-positive type 3 innate lymphoid cells provide the required active LT signaling to prevent the development of splenomegaly.Thus,this study demonstrates the importance of LT-mediated immune responses for the prevention of splenomegaly and systemic inflammation induced by microbiota. | Yuan Zhang Tae-Jin Kim Joanna A Wroblewska Vera Tesic Vaibhav Upadhyay Ralph R Weichselbaum Alexei V Tumanov Hong Tang Xiaohuan Guo Haidong Tang Yang-Xin Fu | 2018 | Cellular & Molecular Immunology2018，15，7： | 3 |
| 16 | 营养和培养参数对深层培养灵芝生产多糖的影响显示文摘研究了各种营养成分和培养参数(pH,温度,氮源可利用性,C∶N,搅拌速度,接种量)对在生物反应器可控条件下利用合成培养基深层培养灵芝生产多糖的影响。所生产的多糖大部分(通常80%以上)为胞外多糖(EPS),分泌到培养液中,菌丝多糖(MAP)只占不到20%。在pH5.0条件下,总多糖(EPS和MAP)生产量和菌丝生长量最高。在28~34℃范围内,多糖产量在34℃培养条件下最高,并随着温度降低而下降。低氮条件下,菌丝生长较弱,多糖产量较低。多糖生产量(主要是胞外多糖)随着接种量的增加而提高,菌丝多糖的生产则相反。利用高效液相色谱(HPLC)凝胶层析法分离出两个胞外多糖组分,其洗脱时间为26.5和36.5 min,分子量分别为137和4.7 kDa;菌丝多糖有一个大的峰(40 min)和一个很小的峰(28 min),其分子量分别为1.57和76.6 kDa。菌丝多糖的HPLC凝胶层析色谱和从灵芝子实体中提取的多糖相似。本研究所采用的各种培养条件下生产的多糖(EPS和MAP)具有可重复性的HPLC色谱。 | 马登波 TANG Jake K-W BUSWELL John A 张树庭 | 2011 | 食用菌学报2011，18，1： | 3 |
| 17 | Coronary plaque erosion without rupture into a lipid core: a frequent cause of coronary thrombosis in sudden coronary death显示文摘 | Farb A Burke AP Tang AL | 1996 | Circulation1996，93，： | 3 |
| 18 | A stop-codon mutation in the human mtDNA cytochrome c oxidase I gene disrupts the functional structure of complex IV显示文摘 | Bruno A Martinuzzi Y Tang Y | 1999 | Am J Hum Genet1999，65，3： | 2 |
| 19 | Organic electroluminescent diodes显示文摘 | Tang C W Vanslyk S A | 1987 | Appl Phys Lett1987，15，： | 2 |
| 20 | 冠状动脉内皮功能障碍患者胆固醇流出异常,高密度脂蛋白颗粒物浓度降低显示文摘冠状动脉内皮功能障碍(endothelial dysfunction,ED)是动脉粥样硬化早期标志,增加心血管事件发生风险。该研究假设胆固醇流出容量和高密度脂蛋白颗粒浓度(high-density lipoprotein particle concentration,HDL-PIMA)较高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)更能预测ED。 | 刘莉 叶鹏 Monette JS Hutchins PM Ronsein GE Wimberger J Irwin AD Tang C Sara JD Shao B Vaisar T Lerman A Heinecke JW | 2016 | 中华高血压杂志2016，24，6： | 2 |
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