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| 1 | Lentinan prolonged survival in patients with gastric cancer receiving S-1-based chemotherapy显示文摘AIM:To examine whether administration of lentinan,purifiedβ-1,3-glucan,can prolong survival in advanced gastric cancer patients receiving S-1-based chemotherapy.METHODS:Since 2004,78 patients with metastatic or recurrent gastric cancer have received S-1-based chemotherapy as first-line treatment.Survival,side effects,and the ratio of granulocytes/lymphocytes(G/L ratio)were compared between 2 groups of patients who received chemo-immunotherapy using lentinan and chemotherapy alone.RESULTS:Median overall survival was significantly longer in the former group than in the latter group[689 d(95%CI:431-2339 d)vs 565 d(95%CI:323-662 d),P=0.0406].In addition,the G/L ratio in patients who received lentinan was maintained around or below 2,which was significantly lower than that in patients who received chemotherapy alone(P<0.001).CONCLUSION:Chemo-immunotherapy with lentinan offers a significant advantage over S-1-based chemotherapy alone in terms of survival in patients with advanced gastric cancer. | Kenji Ina Ryuichi Furuta Takae Kataoka Satoshi Kayukawa Takashi Yoshida Takaya Miwa Yoshitaka Yamamura Yuuki Takeuchi | 2011 | World Journal of Clinical Oncology2011，2，10： | 10 |
| 2 | 帕克菲尔德地区圣安德烈斯断层强度变化的远距离影响因素显示文摘 | Taka’aki Taira Paul G.Silver Fenglin Niu Robert M.Nadeau 左玉玲 | 2009 | 国际地震动态2009，，11： | 2 |
| 3 | Dental pulp cell bank as a possible future source of individual hepatocytes显示文摘Mesenchymal stem cells(MSCs) as a source for regenerative medicine are now the subject of much clinical attention. There are high expectations due to their safety, low tumorigenic risk, and low ethical concerns. MSC therapy has been approved for acute graft-versus host diseases since 2015. Tooth-derived MSCs are known to have a great potential in their proliferation and differentiation capacities, even when compared with bone-marrow-derived MSCs. In particular, stem cells from human exfoliated deciduous teeth(SHEDs) are the best candidates for personal cell banking(dental pulp cell bank), because they can be obtained less invasively in the natural process of individual growth. SHEDs are known to differentiate into hepatocytes. There have been several studies showing the effectiveness of SHEDs on the treatment of liver failure in animal models. They may exert their effects either by repopulation of cells in injured liver or by paracrine mechanisms due to their immuneregulatory functions. Moreover, it may be possible to use each individuals' dental pulp cells as a future source of tailor-made differentiated hepatocytes in the context of a bioartificial liver or liver-on-a-chip to screen for drug toxicity. | Shogo Ohkoshi Haruka Hirono Taka Nakahara Hiroshi Ishikawa | 2018 | World Journal of Hepatology2018，10，10： | 2 |
| 4 | Structure Determination of Polysaccharides in Aloe arborescensvar显示文摘 | Akira Y Hiroshi NM Taka SB | 1986 | Planta Med1986，3，： | 1 |
| 5 | Immunohistochemical study of basic fibroblast growth factor and vascular endothelial growth factor expression for age determination of cutaneous wounds显示文摘 | Taka miga M Saigusa K Aoki Y | 2002 | Am J Forensic Med Pathol2002，23，3： | 1 |
| 6 | Comparative predictive and diagnosis value of flow-mediated vasodilatation in the brachial artery and intima-media thickness of the carotid artery for assessment of coronary artery disease显示文摘 | Matsushima Y Takas B Uehata A | | 0，，02： | 1 |
| 7 | Analysis of complications in hepatic right lobe living donors显示文摘 | Azzam A Uryuhara K Taka I | 2010 | Ann $audi Med2010，30，1： | 1 |
| 8 | Comprehensive proteomics analysis of autophagy-deficient mouse liver显示文摘 | Naomi Matsumoto Junji Ezaki Masaaki Komatsu Katsuyuki Takahashi Reiko Mineki Hikari Taka Mika Kikkawa Tsutomu Fujimura Mitsue Takeda-Ezaki Takashi Ueno Keiji Tanaka Eiki Kominami | 2008 | Biochemical and Biophysical Research Communications2008，，3： | 1 |
| 9 | Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc显示文摘 | Matsunaga S Origuchi N | 1999 | Spine1999，24，14： | 1 |
| 10 | Peripheral lymphocyte reduction in severe acute pancreatitis is caused by apoptotic cell death显示文摘 | Takeyama Y Takas K Ueda T | 2000 | J Gastrointest Surg2000，4，4： | 1 |
| 11 | Development of flow cytometry for detection and quantitation of red cell bound immunoglobulin G in autoimmunehemolytic anemia with negative direct Coombs test显示文摘 | Thedsawad A Taka O Wanachiwanawin W | 2011 | Asian Pac J Allergy Im- munol2011，29，4： | 1 |
| 12 | Numerical Analysis of the Plane Couette Flow of a Rarefied Gas on the Basis of the Linearized Boltzmann Equation for Hard-Sphere Molecules 显示文摘 | Sone Y Taka S Ohwada T | 1990 | European Journal of Mechanics B/ Fluids1990，9，： | 1 |
| 13 | SiC/C multilayered coating contributing to the anti-oxidation of C/C compositions and the suppression of through thickness cracks in the layer 显示文摘 | Takaga Aoki Hiroshi Hatta Taka Hitomi | 2001 | Carbon2001，，10： | 1 |
| 14 | Transition liquid phase bonding of a Hastelloy X and the bond strength at 1173 K显示文摘 | Tetsuro Toyoda Taka O Endo | 1996 | Journal of Materials Science1996，，9： | 1 |
| 15 | Intravascular adi-ministration of polymerized gelatin versus isotonic saline for prevention of spinal-induced hypotention显示文摘 | Baraka AS TaKa SK Ghabach MB | 1994 | Anesth Analg1994，78，2： | 1 |
| 16 | A generalized Lyapunov theorem for descriptor system显示文摘 | TAKA K MORIHIRA N KATAYAMA T | 1995 | Systems Control Letters1995，24，1： | 1 |
| 17 | A study on the surface silanol groups developed byhydrothermal and acid treatment of faujasite type zeolites显示文摘 | Takae Kawai Kazuo Tsutsmi | 1998 | Journal of Colloid andInterface1998，212，： | 1 |
| 18 | PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors 显示文摘 | Takae S Miyata K Oba M | 2008 | J Am Chem Soc2008，130，18： | 1 |
| 19 | Symmetric positive entire solutions of second-order quasilinear degenerate elliptic equations显示文摘 | Yasuhiro Furusho Kusano Taka?i Akio Ogata | 1994 | Archive for Rational Mechanics and Analysis1994，，3： | 1 |
| 20 | In vitro developmental potential of bovine nuclear transfer embryos derived from primary cultured cumulus cells显示文摘 | Mohamed-Nour-Mohamed-Sayed Taka hashi-Yoshiyuki { a } | 2000 | J Vet Med Sci March2000，62，3： | 1 |
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