维普期刊资源整合服务平台（V6.5）

53篇 您的检索式：作者名="TONG CS"

选中清除导出查看参考文献查看引证文献引用追踪共3页首页上一页第1页下一页末页 /3 跳转

	题名	作者	年代	出处	被引量
1	MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside显示文摘MicroRNAs(miRNAs) are small, single-stranded, noncoding RNAs that can post-transcriptionally regulate the expression of various oncogenes and tumor suppressor genes. Dysregulated expression of many miRNAs have been shown to mediate the signaling pathways critical in the multistep carcinogenesis of colorectal cancer(CRC). MiR NAs are stable and protected from RNase-mediated degradation, thereby enabling its detection in biological fluids and archival tissues for biomarker studies. This review focuses on the role and application of miRNAs in the prognosis and therapy of CRC. While stage Ⅱ CRC is potentially curable by surgical resection, a significant percentage of stage Ⅱ CRC patients do develop recurrence. MiRNA biomarkers may be used to stratify such high-risk population for adjuvant chemotherapy to provide better prognoses. Growing evidence also suggests that miRNAs are involved in the metastatic process of CRC. Certain of these miRNAs may thus be used as prognostic biomarkers to identify patients more likely to have micro-metastasis, who could be monitored more closely after surgery and/or given more aggressive adjuvant chemotherapy. Intrinsic and acquired resistance to chemotherapy severely hinders successful chemotherapy in CRC treatment. Predictive miRNA biomarkers for response to chemotherapy may identify patients who will benefit the most from a particular regimen and also spare the patients from unnecessary side effects. Selection of patients to receive the new targeted therapy is becoming possible with the use of predictive miRNA biomarkers. Lastly, forced expression of tumor suppressor miRNA or silencing of oncogenic miRNA in tumors by gene therapy can also be adopted to treat CRC alone or in combination with other chemotherapeutic drugs.	Kenneth KW To Christy WS Tong Mingxia Wu William CS Cho	2018	World Journal of Gastroenterology2018，24，27：	29
2	A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension显示文摘	King Sum Luk Christina Ip Meng-Qi GONG Sunny Hei WONG William KK Wu Mei DONG Guang-Ping LI Ka Pang Chan Yi-Mei DU Tong LIU Martin CS Wong David Shu Cheong Hui Gary Tse	2017	Journal of Geriatric Cardiology2017，14，12：	5
3	Shear wave elastography of thyroid nodules in routine clinical practice: preliminary observations and utility for detecting malignancy 显示文摘	Bhatia KS Tong CS Cho CC	2012	Eur Radiol2012，22，11：	1
4	Shear wave elastography of thyroid nodules in routine Clinical practice:preliminary observations and utility for detecting malignancy显示文摘	Bhatia KS Tong CS		0，，11：	1
5	Shear wave elastography of thy- reid nodules in routine clinical practice: preliminary observations and utility for detecting malignancy 显示文摘	Bhatia KS Tong CS Cho CC	2012	Eur Radiol2012，22，11：	1
6	Shear wave elasticity imaging of cervical lymph nodes 显示文摘	Bhatia KS Cho CC Tong CS	2012	Ulmasound in Meal & Biol2012，38，2：	1
7	Very long-chain acyl-CoA dehydrogenase deficiency presenting as acute hypercapnic respiratory failure 显示文摘	Tong MK Lain CS Mak TW	2006	Eur Respir J2006，28，2：	1
8	Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma显示文摘	Poon RT Ho JW Tong CS		0，，10：	1
9	Shear wave elasticity imaging of cervical lymph nodes显示文摘	Bhatia KS Cho CC Tong CS	2012	Ultrasound Me Biol2012，38，2：	1
10	Intrinsic ligament and triangular fibrocartilage complex tears of the wrist: comparison of MDCT arthrography, conventional 3-T MRI, and MR arthrography 显示文摘	Lee RK Ng AW Tong CS	2013	Skeletal Radiol2013，42，9：	1
11	Shear wave elastography of thyroid nodules in routine clinical practice:preliminary observations and utility for detecting malignancy显示文摘	Bhatia KS Tong CS Cho CC		0，，11：	1
12	High rate and changing molecular epidemiology pattern of norovirus infections in sporadic cases and outbreaks of gastroenteritis in Hong Kong显示文摘	Lau CS Wong DA Tong LK	2004	J Med Virol2004，76，1：	1
13	Fast Fractal Image Encoding based on Adaptive Search显示文摘	TONG CS PI M	2001	IEEE Transactions on Image Processing2001，10，9：	1
14	High rate and changing molecular epidemiology pattern of norovirus infections in sporadic cases and outbreaks of gastroenteritis in Hong Kong显示文摘	LAU CS WONG DA TONG LK	2004	J Med Virol2004，73，1：	1
15	Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma显示文摘	Poon RT Ho JW Tong CS	2004	Br J Surg2004，91，10：	1
16	C-reactive protein and insulin resistance in subjects with thalassaemia minor and a family history of diabetes显示文摘	Tong PCY Ng MC Ho CS	2002	Diabet Care2002，25，8：	1
17	Adaptive approximate nearest neighbour search for fractal image compression显示文摘	Tong CS Wong M	2002	IEEE Transactions on Image Processing2002，11，6：	1
18	Shear wave elastogra- phy of thyroid nodules in routine clinical practice:prelimi- nary observations and utility for detecting malignancy显示文摘	Bhafia KS Tong CS Cho CC	2012	Eur Radiol2012，22，11：	1
19	Clinical significance of sermn vascular cell adhesion molecule-1 levels in patients with hepatocellular carcinoma 显示文摘	Ho JW Poon RT Tong CS	2004	World J Gastroenterol2004，10，14：	1
20	Prognostic significance of serum vascular endothelial growth factor andendostatin in patients with hepatocellular carcinoma 显示文摘	Poon RT Ho JW Tong CS	2004	Br J Surg2004，91，10：	1

返回顶部每页显示：

共3页首页上一页第1页下一页末页 /3 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示