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| 1 | Genetics of coronary artery disease and myocardial infarction显示文摘Atherosclerotic coronary artery disease(CAD) comprises a broad spectrum of clinical entities that include asymptomatic subclinical atherosclerosis and its clinical complications, such as angina pectoris, myocardial infarction(MI) and sudden cardiac death. CAD continues to be the leading cause of death in industrialized society. The long-recognized familial clustering of CAD suggests that genetics plays a central role in its development, with the heritability of CAD and MI estimated at approximately 50% to 60%. Understanding the genetic architecture of CAD and MI has proven to be difficult and costly due to the heterogeneity of clinical CAD and the underlying multi-decade complex pathophysiological processes that involve both genetic and environmental interactions. This review describes the clinical heterogeneity of CAD and MI to clarify the disease spectrum in genetic studies, provides a brief overview of the historical understanding and estimation of the heritability of CAD and MI, recounts major gene discoveries of potential causal mutations in familial CAD and MI, summarizes CAD and MIassociated genetic variants identified using candidate gene approaches and genome-wide association studies(GWAS), and summarizes the current status of the construction and validations of genetic risk scores for lifetime risk prediction and guidance for preventive strategies. Potential protective genetic factors against the development of CAD and MI are also discussed. Finally, GWAS have identified multiple genetic factors associated with an increased risk of in-stent restenosis following stent placement for obstructive CAD. This review will also address genetic factors associated with in-stent restenosis, which may ultimately guide clinical decision-making regarding revascularization strategies for patients with CAD and MI. | Xuming Dai Szymon Wiernek James P Evans Marschall S Runge | 2016 | World Journal of Cardiology2016，8，1： | 15 |
| 2 | The adaptive efficiency of land use planning measured by the control of urban sprawl. The cases of the Netherlands, Belgium and Poland显示文摘 | Jean-Marie Halleux Szymon Marcinczak Erwin van der Krabben | 2012 | Land Use Policy2012，，4： | 3 |
| 3 | Synthesis of luminescent KY_3F_(10) nanopowder multi-doped with lanthanide ions by a co-precipitation method显示文摘A series of KY_3F_(10) nanophosphors doped with Gd^(3+), Ce^(3+) and Eu^(3+) ions were obtained with the use of a co-precipitation method. The resulting products were white precipitates, consisting of spherical particles with diameter about 150–200 nm, which was confirmed using transmission electron microscopy(TEM) technique. Powder X-ray diffraction(XRD) and energy dispersive X-ray analysis(EDX) measurements confirmed appropriate structures of the nanoparticles obtained. Spectroscopic properties of the products were examined on the basis of the measured excitation/emission spectra and luminescence decay curves. The synthesized samples showed orange-red luminescence, characteristic for Eu^(3+) ions. The reaction process was performed in required alkaline pH adjusted with the use of ethylenediaminetetraacetic acid(EDTA) and potassium hydroxide. The samples containing large amounts of Gd^(3+) dopant ions exhibited a tendency to form products with different morphologies. | Szymon Goderski Marcin Runowski Stefan Lis | 2016 | Journal of Rare Earths2016，34，8： | 2 |
| 4 | Biosorption of heavy metals from aqueous solutions onto peanut shell as a low-cost biosorbent显示文摘 | Anna Witek-Krowiak Roman G. Szafran Szymon Modelski | 2010 | Desalination2010，，1： | 2 |
| 5 | Biosorption of heavy metals from aqueous solutions onto peanut shell as a low-cost biosorbent显示文摘 | Anna Witek-Krowiak Roman G. Szafran Szymon Modelski | 2010 | Desalination2010，，1： | 2 |
| 6 | Cardiac implications of thrombotic thrombocytopenic purpura显示文摘Thrombotic thrombocytopenic purpura(TTP) is a multisystem disorder that essentially can affect any organ in the human body. The hallmark of the pathogenesis in TTP is the large von Willebrand factor multimers on plateletmediated micro-thrombi formation, leading to microvascular thrombosis.Autopsy studies showed that cardiac arrest and myocardial infarction are the most common immediate causes of death in these patients. Clinical manifestations of cardiac involvement in TTP vary dramatically, from asymptomatic elevation of cardiac biomarkers, to heart failure, MI and sudden cardiac death. There is limited knowledge about optimal cardiac evaluation and management in patients with TTP. The absence of typical cardiac symptoms,combined with complicated multi-organ involvement in TTP, may contribute to the under-utilization of cardiac evaluation and treatment. Prompt diagnosis and timely initiation of effective therapy could be critically important in selected cases. Based on our experience and this review of the literature, we developed several recommendations for focused cardiac evaluation for patients with acute TTP:(1) patients with suspected or confirmed TTP should be screened for the potential presence of cardiac involvement with detailed history and physical,electrocardiogram and cardiac enzymes;(2) clinical deterioration of TTP patients warrants immediate cardiac reevaluation;(3) TTP patients with clinical evidence of cardiac involvement should be monitored for telemetry, cardiac biomarkers and evaluated with transthoracic echocardiography. These patients require urgent targeted TTP treatment as well as cardiac-specific treatment. Aspirin therapy is indicated for all TTP patients. Since epicardial coronary artery involvement is rare, cardiac catheterization is usually not required, given the high risk for hemorrhage and kidney injury;(4) we recommend evidence-based medical therapy for ischemic symptoms and heart failure. TTP patients with evidence of cardiac involvement would also benefit from routine cardiology follow up during remission. | Szymon L Wiernek Bo Jiang Gregory M Gustafson Xuming Dai | 2018 | World Journal of Cardiology2018，10，12： | 2 |
| 7 | Alternative Polyadenylation of the Sense Transcript Controls Antisense Transcription of DELAY OF GERMINATION 1 in Arabidopsis显示文摘 | Justyna Kowalczyk Malgorzata Palusinska Agata Wroblewska-Swiniarska Zbigniew Pietras Lukasz Szewc Jakub Dolata Artur Jarmolowski Szymon Swiezewski | 2017 | Molecular Plant2017，10，10： | 2 |
| 8 | Surface texture formation in precision machining of direct laser deposited tungsten carbide显示文摘 | Szymon Wojciechowski Zbigniew Nowakowski Radomir Majchrowski Grzegorz Krolczyk | 2017 | Advances in Manufacturing2017，5，3： | 2 |
| 9 | Real-time 3D model acquisition显示文摘 | Szymon Rusinkiewicz Olaf Hall-Holt Marc Levoy | 2002 | ACM Transactions on Graphics (TOG)2002，，3： | 1 |
| 10 | When is the Isbell topology a group topology? 显示文摘 | Szymon Dolecki Frederic Mynard | 2010 | Topology and its Appli- cations2010，157，： | 1 |
| 11 | Efficiently combining positions and normals for precise 3D geometry显示文摘 | Diego N Szymon R James D | 2005 | ACM Transactions on Graphics2005，24，3： | 1 |
| 12 | Studies toward novel peptidomimetic inhibitors of thioredoxin-thioredoxin reductase system显示文摘 | Szymon K Angelika M Malgorzata F | 2012 | J Med Chem2012，55，： | 1 |
| 13 | High sensitivity of human melatonin, alertness, thermo- regulation, and heart rate to short wavelength light 显示文摘 | Christian Cajochen Mirjam Muiich Szymon Kobialka | 2005 | The Journal of Clinical Endocrinology & Metabolism2005，90，3： | 1 |
| 14 | Exaggerated shading for depicting shape and detail显示文摘 | Szymon Rusinkiewicz Michael Bums Doug DeCarlo | | 0，，03： | 1 |
| 15 | On the existence of solution to the stochastic Navior - Stokes equations 显示文摘 | Marek Capinski Szymon Peszat | 2001 | Nonlinear Analysis2001，44，： | 1 |
| 16 | When is the Isbell topology a group topology 显示文摘 | Szymon Dolecki Fr6d6ric Mynard | 2010 | Topology and its Applications2010，157，： | 1 |
| 17 | Evaluation of blind source separation for different algorithms based on second order statistics and different spatial configura- tions of directional microphones 显示文摘 | KOCISKI E SZYMON D EDWARD O | 2012 | Applied Acous- tics2012，73，2： | 1 |
| 18 | Voltammetric Determination of the Neonicotinoid Insecticide Thiamethoxam Using a Tricresyl Phosphate-based Carbon Paste Electrode显示文摘 | ZSIGMOND J P VALERIA J G SZYMON K | 2010 | Journal of the Serbian Chemical Society2010，75，5： | 1 |
| 19 | New high-energy lead-acid battery with reticulated vitreous carbon as a carrier and current collector 显示文摘 | Andrzej Czerwinski Szymon Obrebowski Zbigniew Rogulski | 2012 | Journal of Power Sources2012，198，： | 1 |
| 20 | The adaptive efficiency of land use planning measured by the control of urban sprawl: The cases of the Netherlands, Belgium and Poland 显示文摘 | Jean-Marie Halleuxa Szymon Marcinczakb Erwin van der Krabbenc | 2012 | Land Use Policy2012，29，4： | 1 |
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