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| 1 | Influence of heat treatment on the machinability and corrosion behavior of AZ91 Mg alloy显示文摘In the present study,AZ91 Mg alloy was heat treated at 410℃ for 6,12 and 24 h to investigate the influence of heat treatment on machinability and corrosion behavior.The effect of soaking time on the amount and distribution of Mg 17 Al 12(β-phase)was analyzed under the optical microscope.Microhardness measurements demonstrated the increased hardness with increased heat treatment soaking time,which can be attributed to the solid solution strengthening.The influence of super saturatedα-grains on reducing the cutting force(F z)with respect to increased cutting speed was observed as prominent.The corrosion behavior of the heat treated specimens was studied by conducting electrochemical tests.Surprisingly,corrosion rate of heat treated samples was observed as increased compared with the base material.From the results,it is evident that the machinability of AZ91 Mg alloy can be improved by producing super saturatedα-grains through heat treatment but at the cost of losing corrosion resistance. | Swetha Chowdary V Ravikumar Dumpala Anand Kumar S Kondaiah VV Ratna Sunil B | 2018 | Journal of Magnesium and Alloys2018，6，1： | 7 |
| 2 | 硝基咪唑杂环药物化学研究进展显示文摘硝基咪唑是一类特殊结构的杂环,五元芳香杂环咪唑与硝基的共缀使其衍生物呈现广泛的应用潜力,在药物、人工诊断剂与人工探针等相关领域研究异常活跃,尤其是在医药方面作为人工合成的化学药物已在临床中广泛用于抗癌、抗菌、抗寄生虫等,备受关注.本文结合本课题组相关研究,参考国内外近期文献,系统地综述了硝基咪唑类化合物在药物化学领域的研究与应用,包括抗肿瘤、抗细菌、抗真菌、抗寄生虫、抗结核、抗高血压以及作为人工诊断剂与病理探针、超分子基体等领域的当前现状,展望了其未来可能的发展趋势.希望该评述能为硝基咪唑类杂环化合物的多用途开发提供有益的指导. | 李珍珍 Maddili Swetha Kameswari TangadanchuVijai Kumar Reddy Bheemanaboina Rammohan R.Yadav 林健梅 杨仁国 蔡桂鑫 周成合 | 2019 | 中国科学:化学2019，49，2： | 6 |
| 3 | Discovery of natural berberine-derived nitroimidazoles as potentially multi-targeting agents against drug-resistant Escherichia coli显示文摘A series of natural berberine-derived nitroimidazoles as novel antibacterial agents were designed, synthesized and characterized by nuclear magnetic resonance(NMR), infrared spectra(IR), and high resolution mass spectra(HRMS) spectra. The antimicrobial evaluation showed that some target molecules exhibited moderate to good inhibitory activities against the tested bacteria and fungi including clinical drug-resistant strains isolated from infected patients. Especially, 2-fluorobenzyl derivative8 f not only gave strong activity against drug-resistant E. coli with the minimal inhibitory concentration(MIC) value of0.003 m M, 33-fold more active than norfloxacin, but also exhibited low toxicity toward RAW 264.7 cells and less propensity to trigger resistance. The aqueous solubility and Clog P values of target compounds were investigated to elucidate the structureactivity relationships. Molecular docking and quantum chemical studies for compound 8 f rationally explained its antibacterial effect. The further exploration of antibacterial mechanism revealed that the highly active compound 8 f could effectively permeabilize E. coli cell membrane and intercalate into DNA isolated from resistant E. coli to form 8 f-DNA complex that might block DNA replication to exert the powerful bioactivities. Compound 8 f could also selectively address resistant E. coli from a mixture of various strains. | Guo-Biao Zhang Swetha Kameswari Maddili Vijai Kumar Reddy Tangadanchu Lavanya Gopala Wei-Wei Gao Gui-Xin Cai Cheng-He Zhou | 2018 | Science China Chemistry2018，61，5： | 5 |
| 4 | Evaluating the effectiveness of marine actinobacterial extract and its mediated titanium dioxide nanoparticles in the degradation of azo dyes显示文摘Aim of the present study was to synthesize titanium dioxide nanoparticles(TiO2 NPs) from marine actinobacteria and to develop an eco-friendly azo-dye degradation method. A total of five actinobacterial isolates were isolated from Chennai marine sediments, Tamilnadu, India and analyzed for the synthesis of TiO2 NPs using titanium hydroxide. Among these, the isolate PSV 3 showed positive results for the synthesis of TiO2 NPs, which was confirmed by UV analysis. Further characterization of the synthesized TiO2 NPs was done using XRD, AFM and FT-IR analysis. Actinobacterial crude extract and synthesized TiO2 NPs was found efficient in degrading azo dye such as Acid Red 79(AR-79) and Acid Red 80(AR-80). Degradation percentage was found to be 81% for AR-79, 83% for AR-80 using actinobacterial crude extract and 84% for AR-79, 85% for AR-80 using TiO2 NPs. Immobilized actinobacterial cells showed 88% for AR-79 and 81% for AR-80, dye degrading capacity. Degraded components were characterized by FT-IR and GC-MS analysis. The phytotoxicity test with 500 μg/mL of untreated dye showed remarkable phenotypic as well as cellular damage to Tagetes erecta plant. Comparatively no such damage was observed on plants by degraded dye components. In biotoxicity assay, treated dyes showed less toxic effect as compared to the untreated dyes. | S Priyaragini S Veena D Swetha L Karthik G Kumar K V Bhaskara Rao | 2014 | Journal of Environmental Sciences2014，26，4： | 4 |
| 5 | Quasi-static uni-axial compression behaviour of hollow glass microspheres/epoxy based syntactic foams显示文摘 | SWETHA C KUMAR R | 2011 | Materials & Design2011，32，8： | 1 |
| 6 | Quasi-static uni-axial compression behavior of hollow glass microspheres/epoxy based syntactic foams 显示文摘 | Swetha Ravi kumar | 2011 | Materials and Design2011，，32： | 1 |
| 7 | Quasi-static uni-axial compres- sion be-haviour of hollow glass microspheres/epoxy based syntactic foa-ms 显示文摘 | Swetha C Kumar R | 2011 | Materials and Design2011，32，89： | 1 |
| 8 | Embryonic exposure to octylphenol induces changes in testosterone levels and disrupts reproductive efficiency in rats at their adulthood显示文摘 | S.B. Sainath R. Meena C.H. Venkata Suneel Kumar P. Kalapana K.N. Swetha N. Syamala Devi P. Sreenivasula Reddy | 2011 | Food and Chemical Toxicology2011，，4： | 1 |
| 9 | Quasi-static uni-axial compression behaviour of hollow glass microspheres/epoxy based syntactic foams显示文摘 | C. Swetha Ravi Kumar | 2011 | Materials and Design2011，，8： | 1 |
| 10 | Quasi-static uni-axial compression behaviourof hollow glass microspheres/epoxy based syntactic foams显示文摘 | Swetha C Kumar R | 2011 | Materials and Design2011，32，41： | 1 |
| 11 | Ru(DMSO)4CI2 nano-aggregated Nafion membrane modified electrode for simultaneous electrochemical detection of hypoxanthine, xanthine and uric acid显示文摘 | KUMAR A S SWETHA P | 2010 | J Electroanal Chern2010，642，2： | 1 |
| 12 | Safe surgical zone during TORS radical tonsillectomy:An anatomical and radiological study显示文摘Objective:Parapharyngeal space contains intricate vascular anatomy(external and internal carotid arteries)that might be inadvertently injured during the dissection in this plane.None of the bony landmarks can be used during the transoral robotic surgery(TORS)radical tonsillectomy as these landmarks lie lateral to the internal carotid artery(ICA)and external carotid artery(ECA)in transoral approach.Our study aims to identify the safe surgical limits during the dissection of parapharyneal space in TORS radical tonsillectomy and to correlate the same with radiological study.Material and methods:Fifteen cadavers(30 head and neck regions)and 50 CT-Angiogram of neck(100 head and neck regions)were included in the anatomical and radiological study respectively.The vertical midpoint of anterior tonsillar pillar(palatoglossus muscle)was taken as the reference point and all the measurements were done at the level of reference point both for anatomical and radiological study.Distance between tonsillar fossa and ECA,distance between tonsillar fossa and ICA,relation between ECA and styloglossus and relation between ICA and stylopharyngeus at reference level were studied.Results:The mean distance of ECA from the tonsillar fossa at the reference point was 18.2 mm in the anatomical study and 16.2 mm in the radiological study.The mean distance of ICA from the tonsillar fossa was 23.4 mm and 23.3 mm in the anatomical study and radiological study.There was no significant difference between the anatomical and radiological findings for both the mean distance between ECA and ICA to the tonsillar fossa(p value was 0.45 and 0.30 respectively).ECA was located posterolateral to styloglossus in 24 cases(80.0%)and 79 cases(79.0%)in the anatomical and radiological study respectively.ICA was found posterolateral to stylopharyngeus in 21 cases(70.0%)and 69 cases(69.0%)in the anatomical and radiological study respectively.Conclusion:The muscular plane between styloglossus and stylopharyngeus can be used as an envelope to locate the ECA and ICA that lie medial to these critical vascular structures during TORS.We propose to divide the parapharyngeal space into two compartments(anterior and posterior)based on the surgical perspective of inside-out anatomy.The anterior compartment houses styloglossus muscle with ECA posterolateral to it and the posterior compartment has stylopharyngeus and ICA posterolateral to it. | J.G.Aishwarya Ashish S.Shah Satish Nair Savith Kumar Swetha Kumar K.V.R.Brijith Namrata Srivastava Ameena Ibrahim | 2020 | Laparoscopic, Endoscopic and Robotic Surgery2020，3，2： | 0 |
| 13 | Maxillofacial trauma in a pregnant patient:Contemporary management principles with a case report&review of literature显示文摘Trauma during pregnancy deserves special attention because of its management objectives,i.e.well-being of both pregnant woman and foetus.Maxillofacial trauma directly affects the nutrition of foetus by interfering with the normal functions in a pregnant woman such as mouth opening.mastication and breathing,Hence early restitution of form and function of maxillofacial skeleton is essential.However,the gravid status is associated with numerous anatomical and physiological changes which present with clinical dilemma related to imaging and treatment.A careful scrutiny of the patient's systermic and gestational status is absolutely essential before,during and after instituting any interventional proced-ures.We present a case of bilateral condyle fracture in a 30-year-old pregnant woman in the third trimester(32 weeks).She was treated with inter maxillary fixation using orthodontic brackets&elastics.After successful restitution of occlusion,the patient was advised aggressive physiotherapy which ensured normal mouth opening.Two weeks later,the patient delivered uneventfully.The patient was followed up at one month and 3 month and demonstrated restitution of normal occlusion,mouth opening and lower|acial height.This article aims at analyzing the contermporary principles in management of maxillfacial trauma in a pregnant woman and clarifying the common misconceptions. | Geetha Sridharan Elavenil Panneerselvam Keerthana Ponvel Swetha Tarun V.B.Krishna Kumar Raja | 2020 | Chinese Journal of Traumatology2020，23，2： | 0 |
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