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| 1 | Pre-diagnostic levels of adiponectin and soluble vascular cell adhesion molecule-1 are associated with colorectal cancer risk显示文摘AIM: To examine the relationships between pre-diagnostic biomarkers and colorectal cancer risk and assess their relevance in predictive models.METHODS: A nested case-control study was designed to include all first primary incident colorectal cancer cases diagnosed between inclusion in the SUpplémentation en VItamines et Minéraux AntioXydants cohort in 1994 and the end of follow-up in 2007. Cases (n = 50) were matched with two randomly selected controls (n = 100). Conditional logistic regression models were used to investigate the associations between pre-diagnostic levels of hs-CRP, adiponectin, leptin, soluble vascular cell adhesion molecule-1 (sVCAM-1), soluble intercellular adhesion molecule-1, E-selectin, monocyte chemoattractant protein-1 and colorectal cancer risk. Area under the receiver operating curves (AUC) and relative integrated discrimination improvement (RIDI) statistics were used to assess the discriminatory potential of the models. RESULTS: Plasma adiponectin level was associated with decreased colorectal cancer risk (P for linear trend = 0.03). Quartiles of sVCAM-1 were associated with increased colorectal cancer risk (P for linear trend = 0.02). No association was observed with any of the other biomarkers. Compared to standard models with known risk factors, those including both adiponectin and sVCAM-1 had substantially improved performance for colorectal cancer risk prediction (P for AUC improvement = 0.01, RIDI = 26.5%). CONCLUSION: These results suggest that pre-diagnostic plasma adiponectin and sVCAM-1 levels are associated with decreased and increased colorectal cancer risk, respectively. These relationships must be confirmed in large validation studies. | Mathilde Touvier Léopold Fezeu Namanjeet Ahluwalia Chantal Julia Nathalie Charnaux Angela Sutton Caroline Méjean Paule Latino-Martel Serge Hercberg Pilar Galan Sébastien Czernichow | 2012 | World Journal of Gastroenterology2012，18，22： | 15 |
| 2 | On the fracture of solids characterized by one or two parameters:theory and practice显示文摘 | Chao Y J Yang S Sutton M A | 1994 | Journal of the Mechanics of Physics and Solids1994，42，： | 1 |
| 3 | Calcium signaling and pancreatic cell death: apoptpsis or necrosis? 显示文摘 | Criddle DN Gerasimenko JV Baumgartner HK Jaffar M Voronina S Sutton R Petersen OH Gerasimenko OV | 2007 | Cell Death Differ2007，14，7： | 1 |
| 4 | Atmospheric ammonia : E- mission, deposition and environmental impacts - Introduction 显示文摘 | Sutton M A Lee D S Dollard G J | 1998 | Atmospheric Environment1998，32，： | 1 |
| 5 | Digital image correlation using Newton-Raphson method of partial differential correction显示文摘 | Bruck H A McNeill S R Sutton M A | 1989 | Experimental Mechanics1989，29，3： | 1 |
| 6 | Etiology of apple sooty blotch disease in North Carolina显示文摘 | Johnson E M Sutton T B Hodges C S | 1997 | Phytopathology1997，87，： | 1 |
| 7 | 查看详情显示文摘 | Haynam C A Wegner P J Auerbach J M Bowers M W Dixit S N Erbert G V Heestand G M Henesian M A Hermann M R Jancaitis K S Manes K R Marshall C D Mehta N C Menapace J Moses E Murray J R Nostrand M C Orth C D Patterson R SacksR A Shaw M J Spaeth M Sutton S B W | | 0，，： | 1 |
| 8 | Rates of production of acetate, propionate and butyratein the rumen of lactating dairy cows given normal and low-roughage diets显示文摘 | SUTTON J D DHANOAM M S MORANT S V | 2003 | Journal of Dairy Science2003，86，： | 1 |
| 9 | Digital image correlation using Newton-Rapshon method of partial differential eorrection显示文摘 | Bruck H A McnNeil S R Sutton M A | 1989 | Experimental Mechanics1989，29，3： | 1 |
| 10 | On the fracture of solids characterized by one or two parameters : theory and prac- tice 显示文摘 | Chao Y J Yang S Sutton M A | 1994 | Journal of the Mechanics of Physics of Solids1994，42，4： | 1 |
| 11 | The growth performance,carcass characteristics,and meat quality of halothane carrier and negative pigs显示文摘 | Leach L M Ellis M Sutton D S | 1996 | Journal of Animal Science1996，74，： | 1 |
| 12 | Peltaster fructicola:A new species in the complex of fungi causing apple sooty blotch显示文摘 | Johnson E M Sutton T B Hodges C S | 1996 | Mycologia1996，88，： | 1 |
| 13 | Evoked-potential correlates of stimulus uncertainty显示文摘 | Sutton S Braren M Zubin J | 1965 | Science1965，150，3700： | 1 |
| 14 | Digital image correlation using Newton-Raphson method of partial differential correction 显示文摘 | Bruck H A McNeill S R Sutton M A | 1989 | Experimental Mechanics1989，29，3： | 1 |
| 15 | Evoked-potentialcorrelates of stimulus uncertainty 显示文摘 | SUTTON S BRAREN M ZUBIN J | 1965 | Science?1965，150，3700： | 1 |
| 16 | Digital image correlation using Newton-Raphson method of partialdifferential correction显示文摘 | Bruck H A McNeill S R Sutton M A | 1989 | Experimental Mechanics1989，29，3： | 1 |
| 17 | Differential inhibition of T-type calcium channels by neuroleptics 显示文摘 | Santi C M Cayabyab F S Sutton K G | 2002 | J Neurosci2002，22，2： | 1 |
| 18 | Paying for Im- provements in Quality: Recent Experience in the NHS in England显示文摘 | Meacock R Kristensen S R Sutton M | 2014 | Nordic Journal of Health Economics2014，2，1： | 1 |
| 19 | Cardiac resynchronization induces major structural and functional reverse remodeling in patients with New York Heart Association class Ⅰ/Ⅱ heart failure显示文摘 | St John Sutton M Ghio S Plappert T | 2009 | Circulation2009，120，19： | 1 |
| 20 | Digital image correlation using Newton-Raphson method of partial differential correction显示文摘 | Bruck H A McNeill S R Sutton M A | 1989 | Exp Mech1989，29，3： | 1 |
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