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| 1 | Lack of CD44 variant 6 expression in rectal cancer invasive front associates with early recurrence显示文摘AIM: To investigate the prognostic value of CD44 variant 6 (CD44v6), a membranous adhesion molecule, in rectal cancer. METHODS: Altogether, 210 rectal cancer samples from 214 patients treated with short-course radiotherapy (RT, n = 90), long-course (chemo) RT (n = 53) or surgery alone (n = 71) were studied with immunohistochemistry for CD44v6. The extent and intensity of membranous and cytoplasmic CD44v6 staining, and the intratumoral membranous staining pattern, were analyzed.RESULTS: Membranous CD44v6 expression was seen in 84% and cytoplasmic expression in 81% of the cases. In 59% of the tumors with membranous CD44v6 expression, the staining pattern in the invasive front was determined as 'front-positive' and in 41% as 'front-negative'. The latter pattern was associated with narrower circumferential margin (P = 0.01), infiltrative growth pattern (P < 0.001), and shorter disease-free survival in univariate survival analysis (P = 0.022) when compared to the 'front-positive' tumors. CONCLUSION: The lack of membranous CD44v6 in the rectal cancer invasive front could be used as a method to identify patients at increased risk for recurrent disease. | Suvi Tuulia Avoranta Eija Annika Korkeila Kari Juhani Syrjnen Seppo Olavi Pyrhnen Jari Toivo Tapio Sundstrm | 2012 | World Journal of Gastroenterology2012，18，33： | 9 |
| 2 | A population-based study of 135 lymphomas after solid organ transplantation: The role of Epstein-Barr virus, hepatitis C and diffuse large B-cell lymphoma subtype in clinical presentation and survival显示文摘 | Amelie Kinch Eva Baecklund Carin Backlin Tor Ekman Daniel Molin Gunnar Tufveson Pia Fernberg Christer Sundstr? m Karlis Pauksens Gunilla Enblad | 2014 | Acta Oncologica2014，，5： | 2 |
| 3 | Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence显示文摘 | Sundstr m J Sullivan L D'Agostino RB | 2005 | Hypertension2005，45，1： | 1 |
| 4 | Clinical value of the metabolic syndrome for longterm prediction of total and cardiovascular mortality:prospective,population based cohort study显示文摘 | Risérus U Byberg L | 2006 | BMJ2006，332，： | 1 |
| 5 | Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence显示文摘 | Sundstrm J Sullivan L D'Agostino R B | 2005 | Hypertension2005，45，1： | 1 |
| 6 | Insulin resistance and risk of congestive heart failure显示文摘 | Ingelsson E Sundstr(o)m J Arnl(o)v J | | 0，，03： | 1 |
| 7 | Wear behaviour of some low alloyed steels under combined impact/abrasion contact conditions显示文摘 | Ann Sundstr m José Rendó n Mikael Olsson | 2001 | Wear2001，250，： | 1 |
| 8 | A signal for an abuse liability for pregabalin—results from the Swedish spontaneous adverse drug reaction reporting system显示文摘 | Sofie Schwan Anders Sundstr?m Elisabet Stjernberg Ebba Hallberg P?r Hallberg | 2010 | European Journal of Clinical Pharmacology2010，，9： | 1 |
| 9 | Relations of Serum Uric Acid to Longitudinal Blood Pressure Tracking and Hypertension Incidence显示文摘 | Johan Sundstr?m Lisa Sullivan Ralph B. D’Agostino Daniel Levy William B. Kannel Ramachandran S. Vasan | 2005 | Hypertension2005，，1： | 1 |
| 10 | Prospective study of human papillomavirus(HPV) types,HPV persistence and risk of squamous cell carcinoma of the cervix显示文摘 | Sundstr(o)m K Eloranta S Sparén P | | 0，，10： | 1 |
| 11 | Topical Corticosteroids Do Not Revert the Activated Phenotype of Eosinophils in Eosinophilic Esophagitis but Decrease Surface Levels of CD18 Resulting in Diminished Adherence to ICAM-1, ICAM-2, and Endothelial Cells显示文摘 | Christine Lingblom Henrik Bergquist Marianne Johnsson Patrik Sundstr?m Marianne Quiding-J?rbrink Mogens Bove Christine Wenner?s | 2014 | Inflammation2014，，： | 1 |
| 12 | , Human actions and errors in risk handling-an empirically grounded discussion of cognitive action-regulation levels显示文摘 | Doos M Backstr m T Sundstr m-Frisk C | 2004 | Safety Science2004，42，： | 1 |
| 13 | Cardiac troponin-I and risk of heart failure:a community-based cohort study显示文摘 | Sundstr(O)m J Ingelsson E Berglund L | 2009 | Eur Heart J2009，30，7： | 1 |
| 14 | Wear and failure mechanisms of multilayered PVD TiN/TaN coated tools when milling austenitic stainless steel显示文摘 | Nordin M Sundstr(o)m R Selinder T I | | 0，，： | 1 |
| 15 | Inhomogeneity in plastic deformation of two-phase steels显示文摘 | Karlsson B Sundstr(o)m B O | 1974 | Materials Science and Engineering1974，16，： | 1 |
| 16 | KRAS analysis in colorectal carcinoma:analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice显示文摘 | Sundstr(o)m M Edlund K Lindell M | | 0，，： | 1 |
| 17 | Relations of ser- um uric acid to longitudinal blood pressure tracking and hyperten- sion incidence 显示文摘 | Sundstr~m J Sullivan L D' Agostino RB | 2005 | Hypertension2005，45，1： | 1 |
| 18 | Plasma Parathyroid Hormone and the Risk of Cardiovascular Mortality in the Community显示文摘 | Emil Hagstr?m Per Hellman Tobias E. Larsson Erik Ingelsson Lars Berglund Johan Sundstr?m H?kan Melhus Claes Held Lars Lind Karl Micha?lsson Johan ?rnl?v | 2009 | Circulation2009，，21： | 1 |
| 19 | Circulating biomarkers of extracellular matrix remodeling and risk of atherosclerotic events显示文摘 | Sundstrm J L Vasan R S | 2006 | Curr Opin Lipidol2006，17，1： | 1 |
| 20 | Prognostic value of histological features in diffuse astrocytomas WHO grade Ⅱ 显示文摘 | Lind-Landstrom T Habberstad AH Sundstrφm S | 2012 | Int J Clin Exp Pathol2012，5，2： | 1 |
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