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| 1 | Outline of the Report on Cardiovascular Disease in China,2010显示文摘Major and profound changes have taken place in China over the past 30 years.Rapid socioeconomic progress has exerted a great impact on lifestyle,ranging from food,clothing,working and living conditions,and means of transportation to leisure activities and entertainment.At the same time,new health problems have emerged,and health services are facing new challenges.Presently,cardiovascular diseases (CVD) are among the top health problems of the Chinese people,and pose a serious challenge to all engaged in the prevention and control of these diseases.An epidemic of CVD in China is emerging as a result of lifestyle changes,urbanization and longevity.Both national policy decision-making and medical practice urgently need an authoritative report which comprehensively reflects the trends in the epidemic of CVD and current preventive measures.Since 2005,guided by the Bureau of Disease Prevention of the Ministry of Health of the People's Republic of China and the National Center for Cardiovascular Diseases of China,nationwide experts in the fields of epidemiology,clinical medicine and health economics in the realms of CVD,cerebrovascular disease,diabetes and chronic kidney disease,completed the Report on Cardiovascular Diseases in China every year.The report aims to provide a timely review of the trend of the epidemic and to assess the progress of prevention and control of CVD.In addition,as the report is authoritative,representative and readable,it will become an information platform in the CVD field and an important reference book for government,academic institutes,medical organizations and clinical physicians.This publication is expected to play a positive role in the prevention and control of CVD in China.We present an abstract from the Report on Cardiovascular Diseases in China (2010),including trends in CVD,morbidity and mortality of major CVDs,up-to-date assessment of risk factors,as well as health resources for CVD,and a profile of medical expenditure,with the aim of providing evidence for decision-making in CVD prevention and control programs in China,and of delivering the most authoritative information on CVD prevention and control for all citizens. | HUSheng Shou KONG Ling Zhi GAO Run Lin ZHU Man Lu WANG Wen WANG Yong Jun WU Zhao Su CHEN Wei Wei LIU Ming Bo For the editorial board | 2012 | Biomedical and Environmental Sciences2012，25，3： | 93 |
| 2 | Summary of Report on Cardiovascular Diseases in China,2012显示文摘The prevalence of cardiovascular diseases(CVDs)is associated with the socioeconomic prosperity,lifestyle changes,accelerated process of ageing and urbanization.The prevalence of CVDs is continuously increasing in China and will remain an upward trend in the next 10 years.CVDs are the leading cause of death for Chinese in both urban area and rural area. | WANG Wen HU Sheng Shou KONG Ling Zhi GAO Run Lin ZHU Man Lu WANG Yong Jun WU Zhao Su CHEN Wei Wei YANG Jin Gang MALi Yuan LIU Ming Bo For the editorial board | 2014 | Biomedical and Environmental Sciences2014，27，7： | 31 |
| 3 | EjBZR1 represses fruit enlargement by binding to the EjCYP90 promoter in loquat显示文摘Loquat(Eriobotrya japonica)is a subtropical tree that bears fruit that ripens during late spring.Fruit size is one of the dominant factors inhibiting the large-scale production of this fruit crop.To date,little is known about fruit size regulation.In this study,we first discovered that cell size is more important to fruit size than cell number in loquat and that the expression of the EjBZR1 gene is negatively correlated with cell and fruit size.Virus-induced gene silencing(VIGS)of EjBZR1 led to larger cells and fruits in loquat,while its overexpression reduced cell and plant size in Arabidopsis.Moreover,both the suppression and overexpression of EjBZR1 inhibited the expression of brassinosteroid(BR)biosynthesis genes,especially that of EjCYP90A.Further experiments indicated that EjCYP90A,a cytochrome P450 gene,is a fruit growth activator,while EjBZR1 binds to the BRRE(CGTGTG)motif of the EjCYP90A promoter to repress its expression and fruit cell enlargement.Overall,our results demonstrate a possible pathway by which EjBZR1 directly targets EjCYP90A and thereby affects BR biosynthesis,which influences cell expansion and,consequently,fruit size.These findings help to elucidate the molecular functions of BZR1 in fruit growth and thus highlight a useful genetic improvement that can lead to increased crop yields by repressing gene expression. | Wenbing Su Zikun Shao Man Wang Xiaoqing Gan Xianghui Yang Shunquan Lin | 2021 | Horticulture Research2021，8，1： | 2 |
| 4 | Use of A-192621 and IRL-2500 to Unmask the Mesenteric and Renal Vasodilator Role of Endothelin ETB Receptors显示文摘 | Susan Wai Sum Leung Su Lin Lim Catherine Cheuk Ying Pang Ricky Ying Keung Man | 2002 | Journal of Cardiovascular Pharmacology2002，，4： | 1 |
| 5 | The neuroprotective effect of glial cell line-derived neurotrophic factor in fibrin glue against chronic focal cerebral ischemia in conscious rats 显示文摘 | Henrich Cheng Shiang Suo Huang Su Man Lin | 2005 | Brain Research2005，1033，2005： | 1 |
| 6 | Ladder-Type Thienoacenaphthopyrazine-Based Molecules:Synthesis,Properties,and Application to Construct High-Performance Polymer for Organic Solar Cells显示文摘We present a new design strategy to synthesize ladder-type thienoacenaphthopyrazine(TAP)-based monomers through two different coupling reactions from starting material 5,6-dibromoacenaphthylene-1,2-dione.By bringing varous electron-deficient groups together(such as five-membered aromatic rings,pyrazine,fluorine,and thiadiazols),this new family of molecules exhibits good stability in ambient conditions and easily tunes the electronic,photophysical and film-forming properties of polymers.The unique molecular shape with its extendedπ-conjugated backbone perpendicular to the polymer chain,offers a remarkable platform for the development of a semiconducting polymer with rare geometry.The planar and enlarged conjugated backbone enables TAP-based copolymers PTAP1 and PTAP2 to exhibit distinguishing solubility properties that are different from small-molecule-based polymers,indicating the advantages of novel ladder-type monomers.Their insolubility in chloroform supports orthogonal solvent processing to fabricate layer-by-layer organic solar cells(LBL-OSCs).Owing to its shorterπ–πstacking distance,higher hole mobility,and more favorable phase separation caused bymultifluorine substitution,polymer PTAP1-based LBL-OSC exhibits the highest efficiency of 17.14%by using Y6-BO as the electron acceptor while the efficiency for the PTAP2-based device is 14.20%.This high efficiency indicates the tremendous potential of these novel building units. | Pengwei Han Man Lin Qiuju Jiang Haijun Ning Mingbin Su Li Dang Feng He Qinghe Wu | 2023 | CCS Chemistry2023，5，6： | 0 |
| 7 | Robust reinforcement learning with UUB guarantee for safe motion control of autonomous robots显示文摘This paper addresses the issue of safety in reinforcement learning(RL)with disturbances and its application in the safety-constrained motion control of autonomous robots.To tackle this problem,a robust Lyapunov value function(rLVF)is proposed.The rLVF is obtained by introducing a data-based LVF under the worst-case disturbance of the observed state.Using the rLVF,a uniformly ultimate boundedness criterion is established.This criterion is desired to ensure that the cost function,which serves as a safety criterion,ultimately converges to a range via the policy to be designed.Moreover,to mitigate the drastic variation of the rLVF caused by differences in states,a smoothing regularization of the rLVF is introduced.To train policies with safety guarantees under the worst disturbances of the observed states,an off-policy robust RL algorithm is proposed.The proposed algorithm is applied to motion control tasks of an autonomous vehicle and a cartpole,which involve external disturbances and variations of the model parameters,respectively.The experimental results demonstrate the effectiveness of the theoretical findings and the advantages of the proposed algorithm in terms of robustness and safety. | ZHANG RuiXian HAN YiNing SU Man LIN ZeFeng LI HaoWei ZHANG LiXian | 2024 | Science China(Technological Sciences)2024，67，1： | 0 |
| 8 | Intrinsically Viscoelastic Supramolecular Conjugated Polymer toward Suppressing Coffee-Ring Effect显示文摘The rational molecular design of light-emitting conjugated polymers that inherently suppress the ubiquitous coffee-ring effect(CRE)is a great challenge and the critical bottleneck for printing displays.Herein,we describe a supramolecular route to construct an intrinsically viscoelastic rigid conjugated polymer(RCP)(PHDPF-Cz)toward avoiding the CRE without sacrificing optoelectronic properties.Theπ-πstacking interactions derived fromthe pendant carbazole(Cz)units enable PHDPF-Cz to self-assemble into criss-cross nanofibers and endow its solutionwith great viscosity.Consequently,a high-quality and continuous PHDPFCz film was obtained by impeding the transport of aggregates to the droplet edge due to outward capillary flow during evaporation,in sharp contrast to the random aggregate migration and rapid precipitation generated fromthe controlled poly[4-(6-(9H-diphenylaniline-9-yl)hexyloxy)-9,9-diphenylfluorene]-co-[5-(6-(9H-diphenylaniline-9-yl)hexyloxy)-9,9-diphenylfluorene]and poly(9,9-dioctylfluorene)solutions.Finally,an efficient random laser is also achieved based on these cross-linked films with ultrastable single-chain excitonic behavior,confirming the effectiveness of our design strategy. | Yamin Han Lubing Bai Xiang An Man Xu Chuanxin Wei Zongqiong Lin Mengna Yu Jinyi Lin Lili Sun Ning Sun Changting Wei Linghai Xie Xuehua Ding Qi Wei Chengrong Yin Chenghui Li Wenming Su Wei Huang | 2022 | CCS Chemistry2022，4，11： | 0 |
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