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| 1 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013，19，46： | 6 |
| 2 | Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells显示文摘 | Saiyong Zhu Raiesh Ambasudhan Woong Sun Hyun Jung Kim Maria Talantova Xiaojing Wang Mingliang Zhang Yu Zhang Timothy Laurent James Parker Han-Seop Kim Jeffrey D Zaremba Sofiyan Saleem Sara Sanz-Blasco Eliezer Masliah Scott R McKercher Yee Sook Cho Stuart A Lipton Janghwan Kim Sheng Ding | 2014 | Cell Research2014，24，1： | 6 |
| 3 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 4 | NEMO Satellite Sensor Imaging Payload 显示文摘 | Myers W A Smith R D Stuart J L | 1998 | Proceeding of SPIE1998，3437，： | 1 |
| 5 | Effectual Versus Predictive Logics in Entrepreneur-ial Decision-making:Differences between Expertsand Novices显示文摘 | NICHOLAS D STUART R SARAS D S | 2008 | Journal of Business Venturing2008，26，3： | 1 |
| 6 | Exponential mean- square stability of numerical solutions to stochastic differ- ential equations 显示文摘 | Higham D J Mao X R Stuart A M | 2003 | LMS Journal of Computation and Mathematics2003，6，： | 1 |
| 7 | Valuing Customers 显示文摘 | Gupta S Lehmann D R Stuart J A | 2004 | Journal of Marketing Research2004，41，1： | 1 |
| 8 | Novel drying process using forced aeration through a porous biomass matrix 显示文摘 | Frei K M Cameron D Stuart P R | 2004 | Drying Technology2004，22，5： | 1 |
| 9 | Assessment of eccentric exercise-induced muscle damage of the elbow flexors by tensiomyography 显示文摘 | Angus M Hunter Stuart D R Galloway Iain J S | 2012 | Journal of Electromyography and Kinesiology2012，22，3： | 1 |
| 10 | Long-term outcome for arthroscopic repair of partial articular-sided supraspinatus tendon avulsion显示文摘 | Stuart K D Karzel R P Ganjianpour M | 2013 | Arthroscopy2013，29，5： | 1 |
| 11 | Fomannoxin, a phytotoxic metabolite of Fomes annosus:in vitro production, host toxicity and isolation from naturally infected Sitka spruce heartwood显示文摘 | M C Heslin M R Stuart P O Murchu and D MX Donnelly | 1983 | European Journal Forest Pathology1983，，13： | 1 |
| 12 | Novel drying processusing forced aeration through a porous biomass matrix显示文摘 | Frei K M Cameron D Stuart P R | 2004 | Drying Technology2004，22，5： | 1 |
| 13 | Optimum compaction temperature formodified binders显示文摘 | Azari H McCuen R H Stuart K D | 2003 | Journal of Transportation Engineering2003，129，5： | 1 |
| 14 | The catalytic cross - coupling of unactivated arenes 显示文摘 | STUART D R FAGNOU K | 2007 | Science2007，316，5828： | 1 |
| 15 | Elements of regiocontrol in palladium -catalyzed oxidative arene cross -coupling 显示文摘 | STUART D R VILLEMURE E FAGNOU K | 2007 | J Am Chem Soc2007，129，12： | 1 |
| 16 | Multiple envi ronmental controls on phytoplankton growth strategies determine adaptive responses of the N : P ratio 显示文摘 | Stuart J D James R C Timothy M L | 2014 | E cology Letters2014，17，4： | 1 |
| 17 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 1 |
| 18 | Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial显示文摘 | Raj R Makkar Rachel R Smith Ke Cheng Konstantinos Malliaras Louise EJ Thomson Daniel Berman Lawrence SC Czer Linda Marbán Adam Mendizabal Peter V Johnston Stuart D Russell Karl H Schuleri Albert C Lardo Gary Gerstenblith Eduardo Marbán | 2012 | The Lancet2012，，9819： | 1 |
| 19 | Three 2 dimensional structure of foot-and-mouth disease virus at resolution 显示文摘 | Achara R Fry E Stuart D | 1989 | Nature1989，337，6209： | 1 |
| 20 | Solid-state fermentation in rotating drum bioreactors: operating variables affect performance through their effects on transport phenomena 显示文摘 | STUART D M MITCHELL D A JOHNS M R | 1999 | Biotechnol Bioeng1999，63，： | 1 |
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