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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | 踝关节创伤后关节炎的相关危险因素:一项随访18年的回顾性研究显示文摘踝关节创伤后关节炎十分常见,其发生率比髋膝关节高得多,而目前对其危险因素评估的长期随访研究报道很少。作者对1988年1月-1997年12月的373例进行切开复位内固定的踝关节骨折进行了回顾性研究,并进行统计学分析。Pilon骨折、距骨骨折及年龄〈18岁者未纳入研究。 | Lübbeke A Salvo D Stern R Hoffmeyer P Holzer N Assal M. 于涛 俞光荣 | 2012 | 中国矫形外科杂志2012，20，18： | 14 |
| 3 | The Determinants of National Innovative Capacity显示文摘 | FURMAN JEFFERY L MICHAEL E P SCOTT STERN | 2002 | Research Policy2002，31，6： | 1 |
| 4 | Value orientations,gender andenvironmental concern显示文摘 | Stern P C Dietz T Kalof L | 1993 | Environment and Behavior1993，，25： | 1 |
| 5 | Large kinetic isotope effeets in modern speleothems显示文摘 | Miekler P J Stern L A Banner J L | 2006 | Geological Soeiety of A- meriea Bulletin2006，118，： | 1 |
| 6 | 5T4 as a target for immunotherapY in renal cell carcinoma显示文摘 | Elkord E Shablak A Stern P L | 2009 | Expert Rev Anticancer Ther2009，9，12： | 1 |
| 7 | Value orientations,gender,and environmental concern显示文摘 | Stern P C Dietz T Kalof L | 1993 | Environment and Behavior1993，25，： | 1 |
| 8 | The role of sustained attention and display medi- um in reading comprehension among adolescents with ADHD and without it 显示文摘 | Stern P Shalev L | 2013 | Res Dev Disabil2013，34，1： | 1 |
| 9 | Relational Exchange Norms, Perceptions of Unfairness, and Retained Hostility in Commercial Litigation显示文摘 | KAUFMANN P J STERN L W | 1988 | Journal of Conflict Resolution1988，32，3： | 1 |
| 10 | Serum resistin is not associated with obesity or insulin resistance in humans显示文摘 | Iqbal N Seshadri P Stern L | | 0，，03： | 1 |
| 11 | Combined marginal folate and riboflavin status affect homocysteine methylation in cuhured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation 显示文摘 | Lathrop Stern L Shane B Bagley P J | 2003 | J Nutr2003，133，9： | 1 |
| 12 | Free fatty acids,insulin resistance,and corrected qt intervals in morbid obesity:effect of weight loss during 6 months with differing dietary interventions显示文摘 | Seshadri P Samaha F F Stern L | 2005 | Endocr Pract2005，11，4： | 1 |
| 13 | Oxygen isotopeevidence of climate change from pedogenic clay minerals in the Hima-layan molasse显示文摘 | Stern L A Chamberlain C P Reynolds R C | 1997 | Geochimica et Cosmochimica Acta1997，61，4： | 1 |
| 14 | A value-belief-norm theory of support for social movements:The case of environmentalism显示文摘 | Stern P C Dietz T Abel T D Guagnano G A Kalof L (1999) | 1999 | Human Ecology Review1999，6，2： | 1 |
| 15 | Campylobacter jejuni -an emerging foodborne pathogen显示文摘 | Altekused S F Stern N J Fields P I Swerdlow D L | 1999 | Emerg Infect Dis1999，5，： | 1 |
| 16 | Values, Beliefs, and Proenvironmental Action: Attitude Formation toward Emergent Attitude Objectsl 显示文摘 | Stern P C Kalof L Dietz T | 1995 | Journal of Applied Social Psychology1995，25，18： | 1 |
| 17 | 查看详情显示文摘 | Woo J H Treu T Barth A J Wright S A Walsh J L Bentz M C Martini P Bennert A N Canalizo G Filippenko A V Gates E Greene J Malkan M A Stern D Minezaki T | | 0，，： | 1 |
| 18 | Oxygen isotope evidence of climate change from pedogenic clay minerals in the Himalayan molasse显示文摘 | Stern L A Chamberlain C P Reynolds R C Jr | 1997 | Geochimica et Cosmochimica Acta1997，61，： | 1 |
| 19 | Serum resistin is not associated with obesity or insulin resistance in humans 显示文摘 | Iqbal N Seshadri P Stern L | 2005 | Eur Rev Med Pharmacol Sci2005，9，3： | 1 |
| 20 | The effects of low carbohydrate versus conventional weight loss diets in severely obese adults:Oneyear follow-up of a randomized trial显示文摘 | Stern L Iqbal N Seshadri P | 2004 | Ann Intern Med2004，140，10： | 1 |
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