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| 1 | Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation. | Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 7 |
| 2 | Multidisciplinary approach for multifocal, bilobar hepatocellular carcinoma: A case report and literature review显示文摘BACKGROUND Hepatocellular carcinoma(HCC) is the second most lethal malignancy worldwide. There has been virtually no change in the survivability of HCC in spite of improvement in therapies. Surgery is considered the ideal first, curative intervention, however most patients present in advanced stages with unresectable disease. Therefore, systemic and liver-directed non-operative therapies are initially offered to downstage the disease. To ensure optimal management, a multidisciplinary team approach is often warranted. Our case highlights the benefits of a multidisciplinary approach in a young woman with multifocal, bilobar HCC.CASE SUMMARY A 36-year-old Chinese woman with untreated hepatitis B was found to have large bilobar HCC during work up for abdominal pain. Her initial serum alphafetoprotein was significantly elevated to 311136 ng/mL. Computed tomography scan demonstrated bulky bilobar liver masses, consistent with intermediate stage HCC, Barcelona Clinic Liver Cancer Stage B. Her case was discussed and a personalized care plan was developed at the Multidisciplinary Center for Advanced Minimally Invasive Liver Oncologic Therapies at the University of Washington. She initially underwent bilobar transarterial chemoembolization with partial response of the left lobar tumor. Salvage hypofractionated proton beam radiation therapy was delivered to the right lobe followed by two additional transarterial chemoembolizations to the left lobe with good response.Finally, to remove left lobar residual disease, she was taken to the operating roomfor a left hepatectomy eleven months after her initial presentation. She continues to be without evidence of disease.CONCLUSION Coordinating the multiple HCC treatment modalities is complex and our case highlights the benefits of a multidisciplinary approach. | Kevin P Labadie Stephanie K Schaub Derek Khorsand Guy Johnson Smith Apisarnthanarax James O Park | 2019 | World Journal of Hepatology2019，11，1： | 2 |
| 3 | Monocyte-derived Wnt5a regulates inflammatory ymphangiogenesis显示文摘 | Roberto Sessa Don Yuen Stephanie Wan Michael Rosner Preethi Padmanaban Shaokui Ge April Smith Russell Fletcher Ariane Baudhuin-Kessel Terry P Yamaguchi Richard A Lang LuChen | 2016 | Cell Research2016，26，2： | 2 |
| 4 | PCR as a Confirmatory Technique for Laboratory Diagnosis of Ma- laria显示文摘 | Stephanie P Johnston Norman J Pieniazek Maniphet V Xayavong | 2006 | J Clin Microbiol2006，44，3： | 1 |
| 5 | Perfluorinated Compounds in Aquatic Organisms at Various Trophic Levels in a Great Lakes Food Chain显示文摘 | Kurunthachalam Kannan Lin Tao Ewan Sinclair Stephanie D Pastva Dave J Jude John P Giesy | 2005 | Archives of Environmental Contamination and Toxicology2005，，4： | 1 |
| 6 | High - resolu-tion profiling of fetal DNA clearance from maternal plasma by mas-sively parallel sequencing显示文摘 | STEPHANIE C Y LEE S W Y JIANG P | 2013 | Clin Chem2013，59，8： | 1 |
| 7 | A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4 显示文摘 | Mark J D Stephanie J | 2001 | Proc Natl Acad Sci USA2001，98，10： | 1 |
| 8 | Effect algorithmic approach for mixed-lubrication in cold rolling显示文摘 | Stephany J Ponthot P | 2004 | Journal of Materials Processing Technology2004，153，2： | 1 |
| 9 | 显示文摘 | Stephanie V Isabel P S Jorge P J | 2007 | Langmuir2007，23，： | 1 |
| 10 | A Pre-regularization Scheme for the Reconstruction of a Spatial Dependent Scattering Albedo Using a Hybrid Ant Colony Optimization Implementation显示文摘 | Stephany S Becceneri J C Souto R P | 2010 | Applied Mathematical Modelling2010，34，3： | 1 |
| 11 | Metal -ion sensing fluorophores with large two - photon absorption cross sections: aza - crown ether substituted donor - acceptor - donor distyryjbenzenes 显示文摘 | Stephanie J K P Osamu T Maria C R | 2004 | J Am Chem Soc2004，126，： | 1 |
| 12 | Wurmian deglaciation of western Lake Geneva (Switzerland) based on seismic stratigraphy显示文摘 | Julien F Stephanie G Andre P | 2011 | Quaternary Science Reviews2011，30，3： | 1 |
| 13 | Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway显示文摘 | Peng J Daniela C Z P Stephanie C | 2004 | Nature neuroscience2004，7，2： | 1 |
| 14 | Effect algorithmic approach for mixed-lubrication in cold rolling显示文摘 | Stephany J Ponthot P | 2004 | Journal of Materials Processing Technology2004，153，2： | 1 |
| 15 | Nicotine Upregulates Its Own Receptors through Enhanced Intracellular Maturation显示文摘 | Jerome S Stephanie P Anne D | 2005 | Neuron2005，46，： | 1 |
| 16 | Influence of heatand refining on formation of CLA isomers in sunflower oil显示文摘 | PIERRE J STEPHANIE B P JEAN-LOUIS S | 2003 | Journal ofthe American Oil Chemists Society2003，80，9： | 1 |
| 17 | International entrepreneurship and geographic location: an empirical examination of new venture internationalization 显示文摘 | STEPHANIE A FERNHABER BRETT ANITRA GILBERT PATRICIA P McDOUGALL | 2008 | Journal of International Business Studies2008，39，： | 1 |
| 18 | Stepwise process for the development of Entecavir resistance in a chronic hepatitis B virus infected patient显示文摘 | Stephanie V Aurelie O Christian P | 2007 | Hepatology2007，1，46： | 1 |
| 19 | Early changes in membrane permeability, production of oxidative burst and modification of PAL activity induced by ergosterol in cotyledons of Mimosa pudica 显示文摘 | Stephanie R Estelle L Jean-Michel P | 2006 | Journal of Experimental Botany2006，57，6： | 1 |
| 20 | Efficient algorithmic approach for mixed-lubrication in cold rolling显示文摘 | Stephany J Ponthot P | 2004 | Journal of Materials Processing Technology2004，153，2： | 1 |
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