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| 1 | Monocyte-derived Wnt5a regulates inflammatory ymphangiogenesis显示文摘 | Roberto Sessa Don Yuen Stephanie Wan Michael Rosner Preethi Padmanaban Shaokui Ge April Smith Russell Fletcher Ariane Baudhuin-Kessel Terry P Yamaguchi Richard A Lang LuChen | 2016 | Cell Research2016，26，2： | 2 |
| 2 | Induction of Epstein-Barr Virus Lytic Replication by Recombinant Adenoviruses Expressing the Zebra Gene with EBV Specific Promoters显示文摘The latent Epstein-Barr virus (EBV) is found in the cells of many tumors. For example, EBV is detectable in almost all cases, and in almost all tumor cells, of non-keratinizing nasopharyngeal carcinoma.Activating the latent virus, which will result in its lytic replication and the death of tumor cells, is a potential approach for the treatment of EBV-associated cancers. In this study, three recombinant adenoviruses were constructed to express the Zebra gene, an EBV gene responsible for switching from the latent state to lytic replication. EBV-specific promoters were used in order to limit Zebra expression in EBV-positive cells, and reduce the potential side effects. The EBV promoters used were Cp, Zp and a dual promoter combining both promoters, CpZp. The Zebra protein was detected in HEK293 cells as well as the EBV-positive D98-HR1 cells infected with recombinant viruses. An EBV lytic replication early antigen, EA-D, was also detected in infected D98-HR1, implying the initiation of lytic replication. In the cell viability assay, Zebra-expressing adenoviruses had little effect on EBV-negative HeLa cells, while significantly reducing the cell viability and proliferation of D98-HR1 cells. The results indicate that EBV virus promoters can be used in adenovirus vectors to express the Zebra gene and induce EBV lytic replication in D98-HR1 cells. | LuCHEN JuanYIN YiCHEN JiangZHONG | 2005 | Acta Biochimica et Biophysica Sinica2005，37，4： | 1 |
| 3 | DOES INFORMATION UNDERMINE BRAND? INFORMATION INTERMEDIARY USE AND PREFERENCE FOR BRANDED WEB RETAILERS显示文摘 | JOELWALDFOGEL LUCHEN | 2006 | The Journal of Industrial Economics2006，，4： | 1 |
| 4 | Effect of Neodymium on Microstructure and High Temperature Creep Properties of Mg-5Al-1Si Alloy显示文摘 | HuangXiaofeng WangQudong ZengXiaoqin ZhuYanping LuChen DingWenjiang | 2004 | Journal of Rare Earths2004，22，3： | 1 |
| 5 | Clinical practice guideline:red blood cell transfusion in adult trauma and critical care显示文摘 | Napolitano LM Kurek S Luchene FA | 2009 | Crit Care Med2009，37，12： | 1 |
| 6 | AN IMPLEMENTATION OF FAST ALGORITHM FOR ELLIPTIC CURVE CRYPTOSYSTEM OVER GF(p)显示文摘The design and implementation of fast algorithms related to Elliptic Curve Cryptography (ECC) over the field GF(p), such as modular addition, modular subtraction, point addition, point production, choice of embedding plaintext to a point, etc. are given. A practical software library has been produced which supports variable length implementation of the ECCbased ElGamal cryptosystem. More importantly, this scalable architecture of the design enables the ECC being used in restricted platforms as well as high-end servers based on Intel Pentium CPU. Applications such as electronic commerce security, data encryption communication, etc.are thus made possible for real time and effective ECC. | LuChen ChenYanpu BianZhengzhong | 2004 | Journal of Electronics(China)2004，21，4： | 1 |
| 7 | On Theory of Science for the Sociology of Sport : New Struc- turalism, Action, Intention and Practical Meaning显示文摘 | LUCHEN G | 1990 | International Re- view for the Sociology of Sport1990，25，： | 1 |
| 8 | The expression of SIRT1 in nonalcoholic fatty liver disease induced by high‐fat diet in rats显示文摘 | Xiang‐QunDeng Lu‐LuChen Ning‐XuLi | 2007 | Liver International2007，，5： | 1 |
| 9 | Dynamic evaporation of droplet with adjuvants under different environment conditions显示文摘Pesticide droplet is evaporating during the falling from the nozzle to the target.This dynamic evaporation is influenced by ambient temperature,relative humidity(RH),adjuvant type and concentration.In the evaporation process,the droplet size at different height is affected by the droplet evaporation.Based on this,this study determined the droplet dynamic evaporation by collecting the droplets from different height via silicone oil method with a certain temperature and RH.Eight adjuvants were chosen,including three organo-silicon,three vegetable oil and two non-ionic,with five concentrations.All droplets were generated by a droplet generator.The results showed that the type of adjuvant,ambient temperature and RH had no significant influence on droplet size generated by droplet generator.All the adjuvants in this experiment cannot reduce dynamic evaporation;Concentration of adjuvant made a difference in dynamic evaporation.This could be because of the property of adjuvant.Organo-silicon adjuvants have a negative correlation with water vapor pressure,it showed less dynamic evaporation at high temperature and RH.Vegetable oil and non-ionic adjuvant,they are the same as the controlled blank that the dynamic evaporation reduces with decreasing temperature and increasing RH. | Zhichong Wang Luchen Lan Xiongkui He Andreas Herbst | 2020 | International Journal of Agricultural and Biological Engineering2020，13，2： | 0 |
| 10 | Ecological footprint of Shandong,China显示文摘Ecological footprint has been given much attention and widely praised as an effective heuristic and pedagogic device for presenting current total human resource use in a way that communicates easily to almost everyone since 1996 when Wackernagel and Rees proposed it as a sustainable development indicator. Ecological footprint has been improving on its calculation and still can be a benchmark to measure sustainable development although there are still ongoing debates about specific methods for calculating the ecological footprint. This paper calculates the ecological footprint of Shandong Province, China with the methodology developed by Wackernagel and analyzes the current situation of sustainable development in Shandong. | CUIYu-jing LucHens ZHUYong-guan ZHAOJing-zhu | 2004 | Journal of Environmental Sciences2004，16，1： | 0 |
| 11 | A novel mesenchymal stem cell-based regimen for acute myeloid leukemia differentiation therapy显示文摘Currently the main treatment of acute myeloid leukemia(AML)is chemotherapy combining hematopoietic stem cell transplantation.However,the unbearable side effect of chemotherapy and the high risk of life-threatening infections and disease relapse following hematopoietic stem cell transplantation restrict its application in clinical practice.Thus,there is an urgent need to develop alternative therapeutic tactics with significant efficacy and attenuated adverse effects.Here,we revealed that umbilical cord-derived mesenchymal stem cells(UC-MSC)efficiently induced AML cell differentiation by shuttling the neutrophil elastase(NE)-packaged extracellular vesicles(EVs)into AML cells.Interestingly,the generation and release of NE-packaged EVs could be dramatically increased by vitamin D receptor(VDR)activation in UC-MSC.Chemical activation of VDR by using its agonist 1a,25-dihydroxyvitamin D3 efficiently enhanced the pro-differentiation capacity of UC-MSC and then alleviated malignant burden in AML mouse model.Based on these discoveries,to evade the risk of hypercalcemia,we synthetized and identified sw-22,a novel non-steroidal VDR agonist,which exerted a synergistic prodifferentiation function with UC-MSC on mitigating the progress of AML.Collectively,our findings provided a non-gene editing MSC-based therapeutic regimen to overcome the differentiation blockade in AML. | Luchen Sun Nanfei Yang Bing Chen Yuncheng Bei Zisheng Kang Can Zhang Nan Zhang Peipei Xu Wei Yang Jia Wei Jiangqiong Ke Weijian Sun Xiaokun Li Pingping Shen | 2023 | Acta Pharmaceutica Sinica B2023，13，7： | 0 |
| 12 | Experimental study and assessment of thermal energy storage mortar with paraffin/recycled brick powder composite phase change materials显示文摘Thermal energy storage recycled powder mortar(TESRM)was developed in this study by incorporating paraffin/recycled brick powder(paraffin/BP)composite phase change materials(PCM).Fourier transform infrared and thermogravimetric analysis results showed that paraffin/BP composite PCM had good chemical and thermal stability.The onset melting temperature and latent heat of the composite PCM were 46.49°C and 30.1 J·g−1.The fresh mortar properties and hardened properties were also investigated in this study.Paraffin/BP composite PCM with replacement ratio of 0%,10%,20%,and 30%by weight of cement were studied.The results showed that the static and dynamic yield stresses of TESRM were 699.4%and 172.9%higher than those of normal mortar,respectively.The addition of paraffin/BP composite PCM had a positive impact on the mechanical properties of mortar at later ages,and could also reduce the dry shrinkage of mortar.The dry shrinkage of TESRM had a maximum reduction about 26.15%at 120 d.The thermal properties of TESRM were better than those of normal mortar.The thermal conductivity of TESRM was 36.3%less than that of normal mortar and the heating test results showed that TESRM had good thermal energy storage performance. | Luchen HAO Jianzhuang XIAO Wanzhi CAO Jingting SUN | 2022 | Frontiers of Structural and Civil Engineering2022，16，10： | 0 |
| 13 | Principal Component Analysis on Semen Quality among Chinese Young Men显示文摘Objective To understand the current semen quality status among Chinese young men and influential factors in China and to explore its evaluation index. Methods A total of 562 healthy male volunteers were recruited during their premarital examinations in seven provincials and municipal regions' MCH centers; descriptive and principal component analyses were used to analyze data.Results The findings show that semen volume (2.61±1.10 mL), sperm density (64.47±34.59×106/mL), percentage of sperm forward progression (59.89%±17.11%), percentage of sperm viability (77.19%±11.87%), and percentage of normal sperm morphology (78.23%±9.15%). The first principal component function is Z1=-8.512 54 + 0.001 36X1' +0.031 92X2'+0.043 52X3'+ 0.039 84X4', which is closely related to percentage of sperm viability (X3), percentage of sperm forward progression (X2), and percentage of normal sperm morphology (X4);The second principal component function is: Z2=0.491 92+ 0.080 80X1- 0.000 58X2 - 0.005 10X3 - 0.018 07X4, which depends on the total sperm count (X1). Conclusion Only 42.3% subjects meet all the common WHO standard of semen quality. The multiple analysis of Z1 showed that the highest Z1 are among subjects from Guizhou, workers, or town residents. Multiple analysis of Z2 showed that the older age when the subjects had the first sexual impulse, the longer period of sexual abstinence and more quantity of sperm they had; the more sexual activity subjects had, the less amount of sperm they had. | Jun-qingWU Er-shengGAO Jian-guoTAO Cui-lingLIANG WenyingLI Qiu-yingYANG Kang-shouYAO Wei-qunLU LuCHEN | 2003 | Journal of Reproduction and Contraception2003，14，1： | 0 |
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