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| 1 | MRI-determined fat content of human liver,pancreas and kidney显示文摘AIM:To assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body weight.METHODS:Magnetic resonance spectroscopy and a previously validated gradient echo magnetic resonance imaging method with Dixon's two point technique were used in this study to quantify fat in liver,pancreas as well as kidney.RESULTS:In 36 volunteers with body mass index(BMI) ranging from 20.0 to 42.9 kg/m2,the median fat content of liver,pancreas and kidney was 2.3%(interquartile range:0.2%-7.8%),2.7%(1.0%-6.5%) and 0.7%(0.1%-1.4%),respectively.BMI and subcutaneous fat correlated significantly with liver and pancreas fat content.We show for the first time the significant correlation of liver and pancreas fat content in healthy controls(r = 0.43,P < 0.01).These observations are related to body weight as measured by BMI and the amount of subcutaneous fat.Kidney fat content is very low and correlates with none of the other fat depots.CONCLUSION:Renal lipid accumulation,unlike the coupled accumulations of fat in liver and pancreas,is not observed in obese subjects.Unlike suggestions made in previous studies,renal lipid accumulation appears not to be involved in the pathogenesis of renal disease in humans. | Paul E Sijens Mireille A Edens Stephan JL Bakker Ronald P Stolk | 2010 | World Journal of Gastroenterology2010，16，16： | 14 |
| 2 | Effect of supplementing head-down displays with 3-Daudio during visual target acquisition显示文摘 | PARKER S P A SIMITH S E STEPHAN K L | 2004 | InternationalJournal of aviation psychology2004，14，3： | 1 |
| 3 | Oil-cracking processes evidence from synthetic petroleum inclusions显示文摘 | Stephane T Marcel E Jacques P | 2003 | Journal of Geochemical Exploration2003，26，7879： | 1 |
| 4 | Company scientist locational links: the case of biotechnology显示文摘 | AUDRETSCH D B STEPHAN P E | 1996 | American Economic Review1996，86，3： | 1 |
| 5 | Labor,leisure and training over the life cycle 显示文摘 | Ryder H E Stafford F P Stephan P E | 1976 | International Economic Review1976，17，： | 1 |
| 6 | Empathic Neural Responses are Modulated by the PerceivedFairness of Others 显示文摘 | Singer T Seymour B 0 ’ Doherty J P Stephan K E Dolan R J FrithC D | 2006 | Nature2006，，439： | 1 |
| 7 | An operational and performance overview of the IRIDIUM low earth orbit satellite system显示文摘 | Stephan R P Richard A R Carl E Fossa Jr | 1999 | IEEE Communications Surveys1999，1，3： | 1 |
| 8 | Age and R~h Productivity of Aca- demic Scientists 显示文摘 | Levin S G Stephan P E | 1989 | Research in Higher Education1989，30，5： | 1 |
| 9 | PCR-SSCP Comparison of 16S rDNA Sequence Diversity in Soil DNA Obtained Using Different Isolation and Purification Methods 显示文摘 | JAMES E M S STEPHAN B JASTIN P | 2001 | Microbiology Ecology2001，36，： | 1 |
| 10 | Effect of temperature and additional carbon sources on phenol degradation by an indigenous soil pseudomonad 显示文摘 | Polymenakou P N Stephanou E G | 2005 | Biodegradation2005，16，5： | 1 |
| 11 | Who's patenting in the university? Evidence from the survey of doctorate recipients显示文摘 | STEPHAN P E GURMU S SUMELL A J BLACK G C | 2007 | Economics of Innovation and New Technology2007，16，2： | 1 |
| 12 | Empathic Neural Responses are Modulated by the PerceivedFairness of Others 显示文摘 | Singer T Seymour B 0 ’ Doherty J P Stephan K E Dolan R J FrithC D | 2006 | Nature2006，，439： | 1 |
| 13 | Transmission grating spectroscopy in the 10 keV range显示文摘 | FILL E STEPHAN K H PREDEHL P | 1999 | RevSeiInstrum1999，70，6： | 1 |
| 14 | Source apportionment urban particulate aliphatic and polynuclear aromatic hydrocarbons (PAHs) using multivariate methods 显示文摘 | Kavouras I G Koutrakis P Tsapakis M Lagoudaki E Stephanou E G Baer D V Oyola P | 2001 | Environ Sci Technol2001，35，11： | 1 |
| 15 | Albumin stimulates the accumulation of extracellular matrix in renal tubular epithelial cells显示文摘 | Stephan J P Mao W Filvaroff E | 2004 | Am J Nephrol2004，24，1： | 1 |
| 16 | Age and Research Productivity of Aca- demic Scientists 显示文摘 | Levin S G Stephan P E | 1989 | Research in Higher Education1989，30，5： | 1 |
| 17 | Research Productivity Over the Life Cycle: Evidence for Academic Scientists 显示文摘 | LEVIN S G STEPHAN P E | 1991 | The American Economic Review1991，81，1： | 1 |
| 18 | Research productivity over the life cycle : evidence for academic scientists 显示文摘 | Levin S G Stephan P E | 1991 | The A- merican Economic Review1991，81，1： | 1 |
| 19 | Age and the Nobel-Prize revisited 显示文摘 | Stephan P E Levin S G | 1993 | Seientometries1993，28，3： | 1 |
| 20 | An augmented Galerkin procedure for the boundary integral method applier to two - dimensional screen and crack problem显示文摘 | Stephan E P Wendland W L | 1984 | Applicable Analysis1984，，18： | 1 |
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