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| 1 | Intraductal papillary neoplasm of the bile ducts: A case report and literature review显示文摘Intraductal papillary neoplasm of the bile duct(IPNB) is a rare bile duct neoplasm mostly found in far eastern nations where hepatolithiasis and clonorchiasis infections are endemic. In western countries,it is very rare and the etiology is unknown. In this article,we report the first IPNB patient we encountered in our clinic and a literature review. The patient is a 38-yearold female with a history of choledocholithiasis who presented with obstructive jaundice. She was found to have a papillary mass at the junction of the right hepatic duct and common hepatic duct with six masses in the liver parenchyma. The immunophenotypic and histologic features of the tumor are consistent with IPNB,gastric subtype. The patient had a partial hepatectomy and has been receiving palliative chemotherapy. In a search of Pub Med database,we collected 354 IPNB patients reported in 22 articles. In these patients,52.8% were from Japan and 27.7% were from western countries including the United States(11.0%). The age of the patients ranged from 35 to 80 years old with an average of 64.6. Male/female ratio was 1.5. Macroscopically,57.5% of the tumors were in the left lobe and 29.5% were in the right lobe. The average size of the tumor were 4.2 cm at the time of diagnosis. Histologically,pancreato-biliary subtype accounted for 41.8%,intestinal 28.0%,gastric 13.5% and oncocytic 16%. An invasive component is most often present in the pancreato-biliary and gastric subtypes. Despite recent advanced technologies,diagnosis of IPNB is still challenging,especially in western countries due to its rarity. Defined clinicopathologic features are in demand for the accurate diagnosis and proper treatment. | Yaohong Tan Clara Milikowski Yanelba Toribio Adam Singer Claudia P Rojas Monica T Garcia-Buitrago | 2015 | World Journal of Gastroenterology2015，21，43： | 19 |
| 2 | Analyzing mobile offshore bases using accelerated boundary-element methods显示文摘 | KRING D KORSMEYER F T SINGER J and WHITE J K | 2000 | Marine Structures2000，13，： | 2 |
| 3 | Coexistence of occult vascular malformations and developmental venous anomalies in the central nervous system: MR evaluation 显示文摘 | Abe T Singer R J Marks MP | 1998 | Am J Nenroradiol1998，19，： | 1 |
| 4 | Evaluation of serum S100B as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction显示文摘 | Foerch C Singer OC Neumann-Haefelin T | 2005 | Arch Neurol2005，62，7： | 1 |
| 5 | Understanding consumption-related sucralose emissions - A conceptual approach combining substance-flow analysis with sampling analysis 显示文摘 | Neset T S Singer H Longree P | 2010 | Sci Total Environ2010，408，16： | 1 |
| 6 | The painful side of empathy 显示文摘 | Singer T Frith C | 2005 | Nature Neuroscience2005，8，： | 1 |
| 7 | The ability of clove oil and MS-222 to minimize handling stress in rainbow trout ( Oncorhynchus mykiss Walbaum ) 显示文摘 | WAGNER G N SINGER T D MCKINLEY R S | 2003 | Aquaculture Research2003，34，： | 1 |
| 8 | The effect of permanganate pre - treatment on trihalonethane formation in drinking water显示文摘 | Singer T | 1980 | Am War Work Assoc1980，10，2： | 1 |
| 9 | Reproductive and oncologic outcomes after progestin therapy for endomettial complex atypical hyperplasia or carcinoma显示文摘 | Kudesia R Singer T Caputo TA | 2014 | Am J Obstet Gyuecol2014，210，3： | 1 |
| 10 | Bench-scale testing of a magnetic ion exchange resin for removal of disinfection by-product precursors 显示文摘 | Boyer T H Singer P C | 2005 | Water Res2005，39，7： | 1 |
| 11 | Polypeptides p40, pOM2, and pAngR are required for iron uptake and for virulence of the marine fish pathogen Vibrio anguillarum 显示文摘 | Singer J T Schmidt K A Reno P W | 1991 | Bacteriology1991，173，3： | 1 |
| 12 | Nitropropionic acid of succinate dehydrogenase by 3-nitropropionate 显示文摘 | Coles C J Edmondson D E Singer T P | 1979 | J Biol Chem1979，54，： | 1 |
| 13 | Mechanism of the neurotoxicity of 1-methyl-4-phenylpyridinium (MPP^+), the toxic bioactivation product of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)显示文摘 | Singer T P Ramsay R R McKeown K | 1988 | Toxicology1988，49，： | 1 |
| 14 | On-field measurement meth- od of vapor injection heat pump system 显示文摘 | Singer E Tran C T RiviSre P | 2014 | International Journal of Refrigeration2014，41，： | 1 |
| 15 | The empathic brain: how, when and why 显示文摘 | De Vignemont F Singer T | 2006 | Trends in Cognitive Sciences2006，10，： | 1 |
| 16 | Evaluation of serum S100B as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction显示文摘 | Foerch C Singer OC Neumann-Haefelin T | 2005 | Arch Neurol2005，62，7： | 1 |
| 17 | Effect of Substrate Roughness and Feedstock Concentration on Growth of Wafer-Scale Graphene atAtmospheric Pressure显示文摘 | Luo Z T Lu Y Singer W D | 2011 | Chemistry of Materials2011，23，： | 1 |
| 18 | Inactivation of succinate dehydrogenase by 3-nitropropionate显示文摘 | COLES C J EEMONDSON D E SINGER T P | 1979 | J Biol Chem1979，254，： | 1 |
| 19 | Variable clinical phenotypes of alpha-thalas- semia syndromes 显示文摘 | Singer S T | 2009 | Scientific World Journal2009，9，： | 1 |
| 20 | Empathic neural responses are modulated by the perceived fairness of others 显示文摘 | Singer T Seymour B O'Doherty J | | Nature0，439，： | 1 |
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