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| 1 | 两种新型骨水泥的组织学和生物力学研究显示文摘我们研制了两种可被骨长入的骨水泥:一种是部分可吸收的骨水泥(PRC),以双酚α-甲基丙烯酸甘油酯(Bis-GMA)为基质,混合硅铝陶瓷和可吸收性聚合体颗粒调制成;另一种是磷酸钙骨水泥(CPC),由磷酸三钙、一水磷酸二氢钙、二水磷酸二钙和黄原胶组成。将这两种骨水泥分别植入家兔股骨和胫骨髁的骨缺损中,植入后2、4、12和24周取材,进行组织学观察和生物力学测试。结果发现,CPC组有递增的骨整合,伴有生物降解及巨噬细胞出现,力学测试显示抗压强度在4周之前一直降低,4周后才轻微升高,弹性模量随时间普遍降低。到第4周时,组织学观察还发现新生骨与CPC边缘直接接触。整个观察过程中未发现炎症反应。PRC组,骨整合及生物降解都很轻微,但在各个观察阶段,其抗压强度比松质骨和CPC组高(p<0.05),在4周之前,它的弹性模量高于松质骨和CPC组,4周后低于松质骨。(Bone 25:41S--45S;1999)。 | 卢建熙 I ABOUT G STEPHAN P VAN LANDUYT J DEJOU M FIOCCHI J LEMAITRE J-P PROUST | 2000 | 医用生物力学2000，15，3： | 10 |
| 2 | Trans-arterial chemoperfusion for the treatment of liver metastases of breast cancer and colorectal cancer: Clinical results in palliative care patients显示文摘AIM To evaluate the clinical value and efficiency of transarterial chemoperfusion(TACP) in patients with liver metastases from breast cancer(BC) and colorectal cancer(CRC).METHODS We treated 36 patients with liver metastases of BC(n = 19, 19 females) and CRC(n = 17; 8 females, 9 males) with repeated TACP. The treatment interval was 4 wk. TACP was performed with gemcitabine(1000 mg/m2) and mitomycin(10 mg/m2), administered within 1 h after positioning the catheter tip in the hepatic artery. Before treatment, the size, location, tumour volume, vascularization and number of liver tumours were evaluated using magnetic resonance imaging(MRI). Tumour response was evaluated according to the Response Evaluation Criteria in Solid Tumors guidelines.RESULTS TACP using gemcitabine and mitomycin for metastases from CRC and BC was performed without any serious side effects. The follow-up MRI showed a therapeutic response in 84.2% of the BC patients-stable disease 47.4% and partial response 36.8%. A progression was seen in 15.8%.CRC patients showed a therapeutic response in 52.9% of cases. A progression of the disease was documented in 47.1% of the patients with CRC. These data show that TACP in patients with liver metastases of BC leads to a significantly better therapeutic response compared with CRC patients(P = 0.042). The median survival time was 13.2 mo for the BC patients, which is significantly longer than for CRC patients at 9.3 mo(P = 0.001).CONCLUSION TACP for liver metastases of BC appears to be a safe and effective palliative treatment with improved outcomes in comparison to patients with CRC. | Tatjana Gruber-Rouh Marcel Langenbach Nagy NN Naguib Nour-Eldin M Nour-Eldin Thomas J Vogl Stephan Zangos Martin Beeres | 2017 | World Journal of Clinical Oncology2017，8，4： | 7 |
| 3 | Is Ulnar Nerve Transposition Beneficial During Open Reduction Internal Fixation of Distal Humerus Fractures?显示文摘 | Ryan C Chen David J Harris Stephane Leduc Joseph J Borrelli Paul Tornetta William M Ricci | 2010 | Journal of Orthopaedic Trauma2010，，7： | 2 |
| 4 | Com- parison between beam-stop and beam-hole array scatter correction techniques for industrial X-ray cone-beam CT显示文摘 | SCHORNER K GOLDAMMER M STEPHAN J | 2011 | Nuclear Instruments and Methods in Physics Research B2011，269，3： | 1 |
| 5 | Photodynamic therapy for symptomatic choroidal hemangioma显示文摘 | Ursula M Schmidt-Erfurth Stephan Michels Christine Kusserow Bernhard Jurklies Albert J Augustin | 2002 | Ophthalmology2002，，12： | 1 |
| 6 | Supply Chain Design in the Food Industry显示文摘 | Jack G A J Vorst Stephan J van Dijk Adrie J M Beulens | 2001 | The International Journal on Logistics Management2001，12，2： | 1 |
| 7 | Sensitivity to cdk1-inhibition is modulated by p53 status in preclinical models of embryonal tumors显示文摘 | Schwermer M Lee S K?ster J van Maerken T Stephan H Eggert A | 2015 | Oncotarget2015，6，15： | 1 |
| 8 | Severe skin erosions and scalp infections in AEC syndrome显示文摘 | Vanderhooft SL Stephan M J Sybert VP | 1993 | Pediatr Dermatol1993，10，4： | 1 |
| 9 | In vitro alterations of intestinal bacterial microbiota in fecal samples during storage显示文摘 | Stephan J O Meike M Kenneth N T | 2004 | Diagnostic Microbiology and Infectious Disease2004，50，： | 1 |
| 10 | Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial显示文摘 | Ralf-Dieter Hofheinz Frederik Wenz Stefan Post Axel Matzdorff Stephan Laechelt J?rg T Hartmann Lothar Müller Hartmut Link Markus Moehler Erika Kettner Elisabeth Fritz Udo Hieber Hans Walter Lindemann Martina Grunewald Stephan Kremers Christian Constantin | 2012 | Lancet Oncology2012，，6： | 1 |
| 11 | Characterisation of single-wall carbon nanotubes produced by CCVD method 显示文摘 | Colomer J F Benoit J M Stephan C | 2001 | Chem Phys Lett2001，345，： | 1 |
| 12 | Real-time estimation of the parameters and fluxes of induction motors 显示文摘 | Stephan J Bodson M | 1994 | IEEE Trans Ind Applicat1994，30，： | 1 |
| 13 | Measures for mold control( part 5 ) : Use of Sodium Diacetate 显示文摘 | Bruemmer J M Stephan H Morgenstern G | 1982 | Getr- erde Mehl Bron1982，36，9： | 1 |
| 14 | Real-time estimation of the parameters and fluxes of induction motors显示文摘 | STEPHAN J BODSON M CHIASSON J | 1989 | IEEE Trans Pow- er Elec1989，4，4： | 1 |
| 15 | Expression of RPS4 in tobacco induces an AvrRps4-indeendent HR that requires EDS1, SGT1 and HSP90显示文摘 | YAN Z STEPHAN D MICHAL S SWIDERSKI M JONES J D G | 2004 | The Plant Journal2004，40，： | 1 |
| 16 | Dysfunction of the hypothalamic-pituitary-adrenal axis and functional somatic symptoms, A longitudinal cohort study in the general population显示文摘 | Lineke M T Stephan J L Judith G M | 2009 | Psychoneuroendocrinology2009，34，6： | 1 |
| 17 | An efficient controller for an adjustable speed induction-motor drive显示文摘 | GARCIA G O LUIS J C STEPHAN R M | 1994 | IEEE Transactions on Industrial Electronics1994，41，5： | 1 |
| 18 | Large-distance and long-time properties of a randomly stirred fluid 显示文摘 | NELSON D R STEPHAN M J | 1977 | Phys Rev1977，16，： | 1 |
| 19 | Nitrite toxicity arising from the use of urea as a fertilizer显示文摘 | COURT M N STEPHAN R C WAID J S | 1962 | Nature1962，194，： | 1 |
| 20 | Methodologies for the assembly of a fiber-coupled MEMS Fourier transform spectrometer显示文摘 | MAYYAS M A SIN J STEPHANOU H | 2009 | Transactions on Components and Packaging Technologies(S1521-3331)2009，32，： | 1 |
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