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157篇 您的检索式：作者名="Spapen"

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	题名	作者	年代	出处	被引量
1	儿茶酚胺类药物对脓毒性休克大鼠心肌的影响显示文摘目的 :利用生化指标和形态学方法研究儿茶酚胺类药物对脓毒性休克大鼠心脏的影响与机制。方法 :用盲肠结扎穿孔术 (CL P)制成大鼠的脓毒性休克模型。采用多巴酚丁胺 (DB)、去甲肾上腺素 (NE)及两者最小剂量联合应用以纠正血压。动物随机分为假手术对照组、CL P对照组、CL P+DB组、CL P+NE组、CL P+DB+NE组 ,每组各 8只大鼠。心肌损害程度应用血清心肌钙蛋白 I(c Tn I)和肌酸激酶 (CK)浓度来表达 ,用光镜与电镜检查心肌组织形态学变化。结果 :脓毒性休克大鼠 c Tn I升高 (P<0 .0 5 ) ,儿茶酚胺类药物浓度不影响 c Tn I的水平 ;但 CK总量水平在儿茶酚胺治疗组升高 (P均 <0 .0 5 ) ;心肌组织形态学检查与 c Tn I的结果相符合。结论 :脓毒性休克心肌损害由缺血引起 ,没有明确的证据显示儿茶酚胺类药物能加重心肌损害。	宋达琳梅少平董研虎 Herbert Spapen	2003	中国危重病急救医学2003，15，11：	6
2	Newly Designed CRRT Membranes for Sepsis and SIRS—A Pragmatic Approach for Bedside Intensivists Summarizing the More Recent Advances: A Systematic Structured Review显示文摘	Patrick M. Honore Rita Jacobs Olivier Joannes-Boyau Jouke De Regt Elisabeth De Waele Viola van Gorp Willem Boer Lies Verfaillie Herbert D. Spapen	2013	ASAIO Journal2013，，2：	2
3	Plasma procalcitonin and C-reactive protein in a cute septic shock:clinical and biological correlate显示文摘	Clae ys R Vinken S Spapen H	2002	Crit Care Med2002，30，4：	1
4	Cardiac troponin I and T are biological narkers of left ventricular dysfunction in septic shock显示文摘	ver Elst KM Spapen HD Nguyen DN		0，，05：	1
5	Diagnostic markers of sepsis in the emergency department显示文摘	Spapen HD Hachimi-Idrissi S Corne L		0，，03：	1
6	Protective effects of N-acetyl-L-cysteine in endotoxemia 显示文摘	Zhang H Spapen H Nguyen DN	1994	Am J Physiol1994，266，52：	1
7	Liver perfusion in sepsis, septic shock, and muhiorgan failure显示文摘	Spapen H	2008	Anat Rec (Hoboken)2008，291，6：	1
8	Soluble fiber reduces the incidence of diarrhea in septic pa- tients receiving total enteral nutrition: a prospective, double-blind, randomized, and controlled trial 显示文摘	Spapen H Diltoer M Van Malderen C	2001	Clin Nut2001，20，4：	1
9	Cardiac troponins I and T are biological markers of left ventricular dysfunction in septic shock显示文摘	Spapen H D Nguyen D N	2000	Clin Chem2000，46，：	1
10	Sepsis-related acture kid- ney injury : A protective effect of drotrecogin alpha ( activated treat- ment 显示文摘	Janssen van Doom K spapen H	2008	Acta Anaesthesiol scand2008，52，9：	1
11	Cardiac troponins I and T are biological markers of left ventricular dysfunction in septic shock显示文摘	ver Elst KM Spapen HD Nguyen DN	2000	Clin Chem2000，46，5：	1
12	Plasma procalcitonin andC-reactive protein in acute septic shock: clinical and biologi-cal correlates 显示文摘	Claeys R Vinken S Spapen H	2002	Crit Care Med2002，30，4：	1
13	Diagnostic markers of sepsis in the emergency department 显示文摘	Spapen HD Hachimi - idrissi S Come L	2006	Acta Clin Belg2006，61，3：	1
14	Ret- rospective evaluation of possible renal toxicity associat- ed with continuous infusion of vancomycin in critically ill patients显示文摘	Spapen HD Janssen van Doom K Dihoer M	2011	Ann Intensive Care2011，1，1：	1
15	Protective effects of N-acetyl-L-cysteine in endotoxemia 显示文摘	Zhang H Spapen H Nguyen DN	1994	Am J Physiol1994，266，52：	1
16	Elevated serum levels of S-100beta protein and neuron-specific enolase are associated with brain injury in patients with severe sepsis and septic shock显示文摘	Spapen H Su F	2006	Crit Care Med2006，34，7：	1
17	Prolonged vs intermittent infusion of piperacillin/tazobactam in critically ill patients:A narrative and sys- tematic review显示文摘	Yusuf E Spapen H Pierard D	2014	J Crit Care2014，29，6：	1
18	Protective effects of N-acetyl-L-cysteine in endotoxemia显示文摘	Zhang HB Spapen H Nguyen DN	1994	Am J Physio1994，266，：	1
19	Cardiac troponins Ⅰ and T are biological markers of left ventricular dysfunction in septic shock显示文摘	Ver Elst KM Spapen HD Nguyen DN	2000	Clin Chem2000，46，：	1
20	Effects of N-acetylcysteine on microalbuminuria and organ failure in acute severe sepsis:results of a pilot study显示文摘	Spapen HD Diltoer MW Nguyen DN		0，，04：	1

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