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| 1 | Spatial modulation of nanopattern dimensions by combining interference lithography and grayscale-patterned secondary exposure显示文摘Functional nanostructures are exploited for a variety of cutting-edge fields including plasmonics,metasurfaces,and biosensors,just to name a few.Some applications require nanostructures with uniform feature sizes while others rely on spatially varying morphologies.However,fine manipulation of the feature size over a large area remains a substantial challenge because mainstream approaches to precise nanopatterning are based on low-throughput pixel-by-pixel processing,such as those utilizing focused beams of photons,electrons,or ions.In this work,we provide a solution toward wafer-scale,arbitrary modulation of feature size distribution by introducing a lithographic portfolio combining interference lithography(IL)and grayscale-patterned secondary exposure(SE).Employed after the high-throughput IL,a SE with patterned intensity distribution spatially modulates the dimensions of photoresist nanostructures.Based on this approach,we successfully fabricated 4-inch wafer-scale nanogratings with uniform linewidths of<5%variation,using grayscale-patterned SE to compensate for the linewidth difference caused by the Gaussian distribution of the laser beams in the IL.Besides,we also demonstrated a wafer-scale structural color painting by spatially modulating the filling ratio to achieve gradient grayscale color using SE. | Zhuofei Gan Hongtao Feng Liyang Chen Siyi Min Chuwei Liang Menghong Xu Zijie Jiang Zhao Sun Chuying Sun Dehu Cui Wen-Di Li | 2022 | Light(Science & Applications)2022,11,5: | 3 |
| 2 | Cerebral regional and network characteristics in asthma patients: a resting-state fMRI study显示文摘Asthma is a serious health problem that involves not only the respiratory system but also the central nervous system.Previous studies identified either regional or network alterations in patients with asthma,but inconsistent results were obtained.A key question remains unclear:are the regional and neural network deficits related or are they two independent characteristics in asthma?Answering this question is the aim of this study.By collecting resting-state functional magnetic resonance imaging from 39 patients with asthma and 40 matched health controls,brain functional measures including regional activity(amplitude of low-frequency fluctuations)and neural network function(degree centrality(DC)and functional connectivity)were calculated to systematically characterize the functional alterations.Patients exhibited regional abnormities in the left angular gyrus,right precuneus,and inferior temporal gyrus within the default mode network.Network abnormalities involved both the sensorimotor network and visual network with key regions including the superior frontal gyrus and occipital lobes.Altered DC in the lingual gyrus was correlated with the degree of airway obstruction.This study elucidated different patterns of regional and network changes,thereby suggesting that the two parameters reflect different brain characteristics of asthma.These findings provide evidence for further understanding the potential cerebral alterations in the pathophysiology of asthma. | Siyi Li Peilin Lv Min He Wenjing Zhang Jieke Liu Yao Gong Ting Wang Qiyong Gong Yulin Ji Su Lui | 2020 | Frontiers of Medicine2020,14,6: | 3 |
| 3 | Optimized prime editing efficiently generates heritable mutations in maize显示文摘Low efficiency is the main obstacle to using prime editing in maize(Zea mays).Recently,prime-editing efficiency was greatly improved in mammalian cells and rice(Oryza sativa)plants by engineering primeediting guide RNAs(pegRNAs),optimizing the prime editor(PE)protein,and manipulating cellular determinants of prime editing.In this study,we tested PEs optimized via these three strategies in maize.We demonstrated that the ePE5max system,composed of PEmax,epegRNAs(pegRNA-evopreQ.1),nicking single guide RNAs(sgRNAs),and MLH1dn,efficiently generated heritable mutations that conferred resistance to herbicides that inhibit 5-enolpyruvylshikimate-3-phosphate synthase(EPSPS),acetolactate synthase(ALS),or acetyl CoA carboxylase(ACCase)activity.Collectively,we demonstrate that the ePE5max system has sufficient efficiency to generate heritable(homozygous or heterozygous)mutations in maize target genes and that the main obstacle to using PEs in maize has thus been removed. | Dexin Qiao Junya Wang Min‐Hui Lu Cuiping Xin Yiping Chai Yuanyuan Jiang Wei Sun Zhenghong Cao Siyi Guo Xue‐Chen Wang Qi‐Jun Chen | 2023 | Journal of Integrative Plant Biology2023,65,4: | 1 |
| 4 | Toll-like receptor-9agonists increase cyclin D1expression partly through activation of activator protein-1in human oral squamous cell carcinoma cells显示文摘 | Min R Siyi L Wenjun Y | 2012 | Cancer Sci2012,103,11: | 1 |
| 5 | Salivary gland adenoid cyst- ic carcinoma with cervical lymph node metastasis : a prelim- inary study of 62 cases 显示文摘 | Min R Siyi L Wenjun Y | 2012 | Int J Oral Maxillofac Surg2012,41,8: | 1 |
| 6 | Salivary gland adenoid cystic carcinoma with cervical lymphnode metastasis: a preliminary study of 62 cases 显示文摘 | Min R Siyi L Wenjun Y | 2012 | Int J Oral Maxillofac Surg2012,41,8: | 1 |
| 7 | High-fidelity and clean nanotransfer lithography using structure-embedded and electrostatic-adhesive carriers显示文摘Metallic nanostructures are becoming increasingly important for both fundamental research and practical devices.Many emerging applications employing metallic nanostructures often involve unconventional substrates that are flexible or nonplanar,making direct lithographic fabrication very difficult.An alternative approach is to transfer prefabricated structures from a conventional substrate;however,it is still challenging to maintain high fidelity and a high yield in the transfer process.In this paper,we propose a high-fidelity,clean nanotransfer lithography method that addresses the above challenges by employing a polyvinyl acetate(PVA)film as the transferring carrier and promoting electrostatic adhesion through triboelectric charging.The PVA film embeds the transferred metallic nanostructures and maintains their spacing with a remarkably low variation of<1%.When separating the PVA film from the donor substrate,electrostatic charges are generated due to triboelectric charging and facilitate adhesion to the receiver substrate,resulting in a high large-area transfer yield of up to 99.93%.We successfully transferred the metallic structures of a variety of materials(Au,Cu,Pd,etc.)with different geometries with a<50-nm spacing,high aspect ratio(>2),and complex 3D structures.Moreover,the thin and flexible carrier film enables transfer on highly curved surfaces,such as a single-mode optical fiber with a curvature radius of 62.5μm.With this strategy,we demonstrate the transfer of metallic nanostructures for a compact spectrometer with Cu nanogratings transferred on a convex lens and for surface-enhanced Raman spectroscopy(SERS)characterization on graphene with reliable responsiveness. | Zhuofei Gan Jingxuan Cai Zhao Sun Liyang Chen Chuying Sun Junyi Yu Zeyu Liang Siyi Min Fei Han Yu Liu Xing Cheng Shuhui Yu Dehu Cui Wen-Di Li | 2023 | Microsystems & Nanoengineering2023,9,1: | 1 |
| 8 | Gradient wettability induced by deterministically patterned nanostructures显示文摘We report a large-scale surface with continuously varying wettability induced by ordered gradient nanostructures.The gradient pattern is generated from nonuniform interference lithography by utilizing the Gaussian-shaped intensity distribution of two coherent laser beams.We also develop a facile fabrication method to directly transfer a photoresist pattern into an ultraviolet(UV)-cured high-strength replication molding material,which eliminates the need for high-cost reactive ion etching and e-beam evaporation during the mold fabrication process.This facile mold is then used for the reproducible production of surfaces with gradient wettability using thermal-nanoimprint lithography(NIL).In addition,the wetting behavior of water droplets on the surface with the gradient nanostructures and therefore gradient wettability is investigated.A hybrid wetting model is proposed and theoretically captures the contact angle measurement results,shedding light on the wetting behavior of a liquid on structures patterned at the nanoscale. | Siyi Min Shijie Li Zhouyang Zhu Wei Li Xin Tang Chuwei Liang Liqiu Wang Xing Cheng Wen-Di Li | 2020 | Microsystems & Nanoengineering2020,6,1: | 1 |
| 9 | An Agent-Assisted QoS-Based Rou- ting Algorithm for Wireless Sensor Networks 显示文摘 | Liu Min Xu Shijun Sun Siyi | 2012 | Journal of Network and Computer Applications2012,35,1: | 1 |
| 10 | Salivary' gland adenoid cystic carcinoma with cervical lymph node metastasis: a preliminary study of 62 eases 显示文摘 | Min R Siyi L Wenjun Y | 2012 | Int J Oral Maxiltofac Snrg2012,41,8: | 1 |
| 11 | Increased expression of MUC- 1 has close relation with patient survivor in high-grade salivary gland mucoepidermoid carcinoma显示文摘 | Siyi L Shengwen L Min R | 2014 | J Oral Pathol Med2014,43,8: | 1 |
| 12 | A Brief Review on He Ion Irradiation Research of Steel and Iron‑Based Alloys in Nuclear Power Plants显示文摘Nuclear power plays a key role as renewable energy in alleviating the worldwide energy shortage.The material degradation caused by high-temperature and high-flux neutron irradiation is the most concerning issue for nuclear reactor safety.A large number of He atoms produced through the(n,α)transmutation reaction diffuse and migrate in metals and accumulate to form He bubbles because of the extremely low solubility of He atoms in metal materials.The helium bubbles gather at the grain boundary or grain to cause swelling,hardening,embrittlement,and other damages to the in-core structural components.This paper mainly summarizes the research progress on He irradiation in steel and iron-based alloys,including the diffusion and accumulation of He atoms,the nucleation and growth of He bubbles,and the microstructure and macroscopic degradation of material performance caused by He irradiation.The mechanism of helium irradiation-induced corrosion in steel and iron-based alloys in recent years is reviewed as well.Moreover,the investigations on irradiation performance in additive manufactured stainless steels are summarized,and the mechanism of irradiation resistance is prospected. | Siyi Qiu Hui Liu Menglei Jiang Shiling Min Yanlin Gu Qingyan Wang Jing Yang Xuejun Li Zhuoer Chen Juan Hou | 2023 | Acta Metallurgica Sinica(English Letters)2023,36,4: | 0 |