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    题名 作者 年代 出处 被引量
1Expression, purification and refolding of recombinant CrylAb/Ac obtained in Escherichia coli as inclusion bodies显示文摘CAO Sishuo XU Wentao LUO Yunbo 2009Sci Food Agric2009,89,:1
2Safety assessmentof Cry 1C protein from genetically modified rice according to thestandards of PR China for a new food resource显示文摘CAO Sishuo HE Xiaoyun XU Wentao 2010RegulatoryToxicology and Pharmacology2010,58,3:1
3Safety assessment of dehydration-responsive element-binding (DREB) 4 protein expressed in E. coli显示文摘Bo Cao Xiaoyun He Yunbo Luo Lina Ma Pengfei Liu Sishuo Cao Yaozheng Liu Shiying Zou Wentao Xu Kunlun Huang 2012Food and Chemical Toxicology2012,,11:1
4Safety assessment of Cry1C protein from genetically modified rice according to the national standards of PR China for a new food resource显示文摘Sishuo Cao Xiaoyun He Wentao Xu Wenjun Ran Lixing Liang YunBo Luo Yanfang Yuan Nan Zhang Xin Zhou Kunlun Huang 2010Regulatory Toxicology and Pharmacology2010,,3:1
5Safety assessment of transgenic Bacillus thuringiensis rice Tlc-19 in Sprague-Dawley rats from metabonomics and bacterial profile perspectives显示文摘CAO Sishuo HE Xiaoyun XU Wentao 2012IUBMB Life2012,64,3:1
6Metabonomics study of transgenic Bacillus thuringiensis rice (T2A-1) meal in a 90-day dietary toxicity study in rats显示文摘CAO Sishuo XU Wentao LUO Yunbo 2011Molecular BioSystems2011,7,7:1
7Safety assessment of Cry1C protein from genetically modified rice according to the standards of PR China for a new food resource显示文摘CAO Sishuo HE Xiaoyun XU Wentao 2010Regulatory Toxicology and Pharmacology2010,58,3:1
8Metabonomics study of transgenic Bacillus thuringiensis rice (T2A-1) meal in a 90-day dietary toxicity study in rats显示文摘CAO Sishuo XU Wentao LUO Yunbo 2011Molecular BioSystems2011,7,7:1
9Electroacupuncture alleviates orofacial allodynia and anxiety-like behaviors by regulating synaptic plasticity of the CA1 hippocampal region in a mouse model of trigeminal neuralgia显示文摘OBJECTIVE To investigate whether electroacupuncture(EA)ameliorates abnormal trigeminal neuralgia(TN)orofacial pain and anxiety-like behavior by altering synaptic plasticity in the hippocampus CA1.METHODS A mouse infraorbital nerve transection model(pTION)of neuropathic pain was established,and EA or sham EA was used to treat ipsilateral acu⁃puncture points(GV20-Baihui and ST7-Xia⁃guan).Golgi-Cox staining and transmission elec⁃tron microscopy(TEM)were administrated to observe the changes of synaptic plasticity in the hippocampus CA1.RESULTS Stable and persistent orofacial allodynia and anxiety-like behav⁃iors induced by pT-ION were related to changes in hippocampal synaptic plasticity.Golgi stain⁃ings showed a decrease in the density of dendritic spines,especially mushroom-type dendritic spines,in hippocampal CA1 neurons of pT-ION mice.TEM results showed that the density of synapses,membrane thickness of the postsynaptic density,and length of the synaptic active zone were decreased,whereas the width of the synaptic cleft was increased in pTION mice.EA attenu⁃ated pT-ION-induced orofacial allodynia and anx⁃iety-like behaviors and effectively reversed the abnormal changes in dendritic spines and syn⁃apse of the hippocampal CA1 region.CONCLU⁃SION EA modulates synaptic plasticity of hippo⁃campal CA1 neurons,and reduces abnormal oro⁃facial pain and anxiety-like behavior,providing evidence for a TN treatment strategy.JIA Yuzhi LI Haitao ZHANG Guangming WU Hongyun ZHANG Sishuo ZHI Hongwei WANG Yahan ZHU Jingwen WANG Yifan XU Xiangqing TIAN Caijun CUI Wenqiang 2023中国药理学与毒理学杂志2023,37,S01:0
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