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| 1 | Hepatitis C virus genotypes in Serbia and Montenegro: The prevalence and clinical signifi cance显示文摘AIM: To investigate the prevalence of hepatitis C virus (HCV) genotypes in Serbia and Montenegro and their in? uence on some clinical characteristics in patients with chronic HCV infection.METHODS: A total of 164 patients was investigated. Complete history, route of infection, assessment of al-cohol consumption, an abdominal ultrasound, standard biochemical tests and liver biopsy were done. Gene se-quencing of 5’ NTR type-specifi c PCR or commercial kits was performed for HCV genotyping and subtyping. The SPSS for Windows (version 10.0) was used for univariate regression analysis with further multivariate analysis. RESULTS: The genotypes 1, 2, 3, 4, 1b3a and 1b4 were present in 57.9%, 3.7%, 23.2%, 6.7%, 6.7% and 1.8% of the patients, respectively. The genotype 1 (mainly the subtype 1b) was found to be independent of age in sub-jects older than 40 years, high viral load, more severe necro-in? ammatory activity, advanced stage of fi brosis, and absence of intravenous drug abuse. The genotype 3a was associated with intravenous drug abuse and the age below 40. Multivariate analysis demonstrated age over 40 and intravenous drug abuse as the positive pre-dictive factors for the genotypes 1b and 3a, respectively. CONCLUSION: In Serbia and Montenegro, the geno-types 1b and 3a predominate in patients with chronic HCV infection. The subtype 1b is characteristic of older patients, while the genotype 3a is common in drug abus-ers. Association of the subtype 1b with advanced liverdisease, higher viral load and histological activity sug-gests earlier infection with this genotype and eventually its increased pathogenicity. | Neda Svirtlih Dragan Delic Jasmina Simonovic Djordje Jevtovic Ljubisa Dokic Eleonora Gvozdenovic Ivan Boricic Dragica Terzic Sladjana Pavic Gorana Neskovic Sonja Zerjav Vladimir Urban | 2007 | World Journal of Gastroenterology2007，13，3： | 5 |
| 2 | Performance and uncertainty analysis of a short-term climate reconstruction based on multi-source data in the Tianshan Mountains region,China显示文摘Short-term climate reconstruction,i.e.,the reproduction of short-term(several decades)historical climatic time series based on the relationship between observed data and available longer-term reference data in a certain area,can extend the length of climatic time series and offset the shortage of observations.This can be used to assess regional climate change over a much longer time scale.Based on monthly grid climate data from a Coupled Model Inter-comparison Project phase 5(CMIP5)dataset for the period of 1850–2000,the Climatic Research Unit(CRU)dataset for the period of 1901–2000 and the observed data from 53 meteorological stations located in the Tianshan Mountains region(TMR)of China during the period of 1961–2011,we calibrated and validated monthly average temperature(MAT)and monthly accumulated precipitation(MAP)in the TMR using the delta,physical scaling(SP)and artificial neural network(ANN)methods.Performance and uncertainty during the calibration(1971–1999)and verification(1961–1970)periods were assessed and compared using traditional performance indices and a revised set pair analysis(RSPA)method.The calibration and verification processes were subjected to various sources of uncertainty due to the influence of different reconstructed variables,different data sources,and/or different methods used.According to traditional performance indices,both the CRU and CMIP5 datasets resulted in satisfactory calibrated and verified MAT time series at 53 meteorological stations and MAP time series at 20 meteorological stations using the delta and SP methods for the period of 1961–1999.However,the results differed from those obtained by the RSPA method.This showed that the CRU dataset produced a low degree of uncertainty(positive connection degree)during the calibration and verification of MAT using the delta and SP methods compared to the CMIP5 dataset.Overall,the calibrated and verified MAP had a high degree of uncertainty(negative connection degree)regardless of the dataset or reconstruction method used.Therefore,the reconstructed time series of MAT for the period of 1850(or 1901)–1960 based on the CRU and CMIP5 datasets using the delta and SP methods could be used for further study.The results of this study will be useful for short-term(several decades)regional climate reconstruction and longer-term(100 a or more)assessments of regional climate change. | LI Xuemei Slobodan P SIMONOVIC LI Lanhai ZHANG Xueting QIN Qirui | 2020 | Journal of Arid Land2020，12，3： | 2 |
| 3 | The influence of single and combined IL28B polymorphisms on response to treatment of chronic hepatitis C显示文摘 | Ivana Lazarevic Jelena Djordjevic Maja Cupic Danijela Karalic Dragan Delic Neda Svirtlih Jasmina Simonovic Petar Svorcan Natasa Milic Tanja Jovanovic | 2013 | Journal of Clinical Virology2013，，： | 2 |
| 4 | Reliability programming in reservoir manage显示文摘 | Marino M A | 1982 | Water Resources Research1982，，4： | 1 |
| 5 | Reservoir systems analysis: closing gap between theory and practice 显示文摘 | Simonovic S P | 1992 | Journal of Water Resources Planning and Management1992，118，3： | 1 |
| 6 | Short term stream flow forecasting using artificial neural networks 显示文摘 | Zealand C M Burn D H Simonovic S P | 1999 | Journal Hydrology1999，214，24： | 1 |
| 7 | Inverse flood risk modeling under changing climatic conditions显示文摘 | Cunderlik J M Simonovic S P | 2007 | Hydrological Processes2007，21，： | 1 |
| 8 | Brain mtastasea after stereotactic radiosurgery using the Leksen gamma knife: can FDG PET help to differentiate radionecrosis from tumour progression?显示文摘 | Bělohhivek O Simonová G Kantorovà L | 2003 | EurJ Nucl Med Mol Imaging2003，30，1： | 1 |
| 9 | Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor显示文摘 | Simonovic M Gettins PG Volz K | 2001 | Proc Natl Acad Sci2001，98，11： | 1 |
| 10 | Estimation of missing streamflow data using principles of chaos theory显示文摘 | Elshorbagy A Simonovic S P Panu U S | 2002 | Journal of Hydrology2002，255，： | 1 |
| 11 | An evolution program for non-linear transportation problems显示文摘 | Ilich N Simonovic S P | 2001 | Journal of Heuristics2001，7，2： | 1 |
| 12 | Com-parative analysis of mimic and autonomic componentsof the emotional state in man显示文摘 | RUSALOVA M N IZARD C E SIMONOV | 1977 | Neuroscience andBehavioral Physiology1977，8，1： | 1 |
| 13 | The role of lamivudine in the treatment of HBe antigen negative liver cirrhosis显示文摘 | Simonovic BJ Delic D Svirtlih N | 2006 | Med Pregl2006，59，9： | 1 |
| 14 | The implicit stochastic model for reservoir yield optimization显示文摘 | Simonovic S P | 1987 | Water Resources Research1987，23，12： | 1 |
| 15 | Spatial system dynamics:a new approach for simulation of water resources systems显示文摘 | Ahmad S Simonovic S P | | 0，，04： | 1 |
| 16 | Spatial and temporal analysis of urban flood risk assessment显示文摘 | AhmadS S and Simonovic S P | 2013 | Urban Water Journal2013，10，1： | 1 |
| 17 | Autoantibodies characteristic for autoimmune hepatitis found in chronic hepatitis C 显示文摘 | Pavic S Simonovic J Boricic I | 2003 | Srp Arh Celok Lek2003，131，： | 1 |
| 18 | The influence of carbon support porosity on the activity ofPt Ru/sibunit anode cata- lysts for methanol oxidation显示文摘 | RAO V SIMONOV P A SAVINOVA E R | 2005 | J Power Sources2005，145，2： | 1 |
| 19 | On the nature of the interaction of H2PdC14 with the surface of graphite-like carbon materals 显示文摘 | Simonov P A Romanenko A V Prosvirin P | 1997 | Carbon1997，35，1： | 1 |
| 20 | System dynamics model for predicting floods from snowmelt in North American prairie watersheds显示文摘 | Li L Simonovic S P | 2002 | Hydrological Processes2002，16，13： | 1 |
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