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| 1 | Treatment status of extremely premature infants with gestational age<28 weeks in a Chinese perinatal center from 2010 to 2019显示文摘Background There is a paucity of studies conducted in China on the outcomes of all live-birth extremely premature infants(EPIs)and there is no unifed recommendation on the active treatment of the minimum gestational age in the feld of perinatal medicine in China.We aimed to investigate the current treatment situation of EPIs and to provide evidence for formulating reasonable treatment recommendations.Methods We established a real-world ambispective cohort study of all live births in delivery rooms with gestational age(GA)between 24+0 and 27+6 weeks from 2010 to 2019.Results Of the 1163 EPIs included in our study,241(20.7%)survived,while 849(73.0%)died in the delivery room and 73(6.3%)died in the neonatal intensive care unit.Among all included EPIs,862(74.1%)died from withholding or withdrawal of care.Regardless of stratifcation according to GA or birth weight,the proportion of total mortality attributable to withdrawal of care is high.For infants with the GA of 24 weeks,active treatment did not extend their survival time(P=0.224).The survival time without severe morbidity of the active treatment was signifcantly longer than that of withdrawing care for infants older than 25 weeks(P<0.001).Over time,the survival rate improved,and the withdrawal of care caused by socioeconomic factors and primary nonintervention were reduced signifcantly(P<0.001).Conclusions The mortality rate of EPIs is still high.Withdrawal of care is common for EPIs with smaller GA,especially in the delivery room.It is necessary to use a multi-center,large sample of real-world data to fnd the survival limit of active treatment based on our treatment capabilities. | Wen-Wen Zhang Yong-Hui Yu Xiao-Yu Dong Simmy Reddy | 2022 | World Journal of Pediatrics2022,18,1: | 8 |
| 2 | Biliary acute pancreatitis:a review显示文摘INTRODUCTIONIt is axiomatic that the most effective and soundlybased plan of treatment of any disorder is one aimedat the mechanism or mechanisms responsible for itsdevelopment.This basic notion,coupled withrecent reports in which,surprisingly there is atotal lack of reference to the probable involvementof autonomic-arc-reflexes in the | Osvaldo M.Tiscomia Susana Hamamura Enriqueta S.deLehmann Graciela Otero Hipolito Waisman Patricia Tiscornia-Wasserman Simmy Bank | 2000 | World Journal of Gastroenterology2000,6,2: | 6 |
| 3 | Crohn's disease and risk of fracture: does thyroid disease play a role?显示文摘AIM: To assess the role of thyroid disease as a risk for fractures in Crohn's patients.METHODS: A cross-sectional study was conducted from 1998 to 2000. The study group consisted of 210 patients with Crohn's disease. A group of 206 patients without inflammatory bowel disease served as controls. Primary outcome was thyroid disorder. Secondary outcomes included use of steroids, immunosuppressive medications, surgery and incidence of fracture.RESULTS: The prevalence of hyperthyroidism was similar in both groups. However, the prevalence of hypothyroidism was lower in Crohn's patients (3.8 % vs 8.2 %, P=0.05).Within the Crohn's group, the use of immunosuppressive agents (0 % vs11 %), steroid usage (12.5 % vs37 %), small bowel surgery (12.5 % vs 28 %) and large bowel surgery (12.5 % vs27 %) were lower in the hypothyroid subset as compared to the euthyroid subset. Seven (3.4 %) Crohn'spatients suffered fracture, all of whom were euthyroid.CONCLUSION: Thyroid disorder was not found to be associated with Crohn's disease and was not found to increase the risk for fractures. Therefore, screening for thyroid disease is not a necessary component in the management of Crohn's disease. | Nakechand Pooran Pankaj Singh Simmy Bank | 2003 | World Journal of Gastroenterology2003,9,3: | 2 |
| 4 | Longer duration of initial invasive mechanical ventilation is still a crucial risk factor for moderate‑to‑severe bronchopulmonary dysplasia in very preterm infants:a multicentrer prospective study显示文摘Objectives We aimed to evaluate the risk factors for moderate-to-severe bronchopulmonary dysplasia(BPD)and focus on discussing its relationship with the duration of initial invasive mechanical ventilation(IMV)in very preterm neonates less than 32 weeks of gestational age(GA).Methods We performed a prospective cohort study involving infants born at 23–31 weeks of GA who were admitted to 47 different neonatal intensive care unit(NICU)hospitals in China from January 2018 to December 2021.Patient data were obtained from the Sina-northern Neonatal Network(SNN)Database.Results We identified 6538 very preterm infants,of whom 49.5%(3236/6538)received initial IMV support,and 12.6%(823/6538)were diagnosed with moderate-to-severe BPD symptoms.The median duration of initial IMV in the moderateto-severe BPD group was 26(17–41)days,while in the no or mild BPD group,it was 6(3–10)days.The incidence rate of moderate-to-severe BPD and the median duration of initial IMV were quite different across different GAs.Multivariable logistic regression analysis showed that the onset of moderate-to-severe BPD was significantly associated with the duration of initial IMV[adjusted odds ratio(AOR):1.97;95%confidence interval(CI):1.10–2.67],late-onset neonatal sepsis(LONS),and patent ductus arteriosus(PDA).Conclusion In this multicenter cohort study,the duration of initial IMV was still relatively long in very premature infants,and the longer duration of initial IMV accounts for the increased risk of moderate-to-severe BPD. | Cong Dou Yong-Hui Yu Qing-Cui Zhuo Jian-Hong Qi Lei Huang Yan-Jie Ding De-Juan Yang Li Li Dan Li Xiao-Kang Wang Yan Wang Xin Qiao Xiang Zhang Bing-Jin Zhang Hai-Yan Jiang Zhong-Liang Li Simmy Reddy | 2023 | World Journal of Pediatrics2023,19,6: | 2 |
| 5 | Mobile systems显示文摘 | Simmy G | 1993 | Industrial Robot1993,20,5: | 1 |
| 6 | The reaction of 2, 5 - dimethylfuran with hydrogen atoms : an exper- imental and theoretical study 显示文摘 | FRIESE P SIMMIE J M OLZMANN M | 2013 | Proceedings of the Combustion Institute2013,34,1: | 1 |
| 7 | A Comprehensive Modeling Study of Hydrogen Oxidation显示文摘 | CONAIRE M CURRAN H J SIMMIE J M | 2004 | International Jour- nal of Chemical Kinetics2004,36,11: | 1 |
| 8 | Formation enthalpies and bond dissociation energies of alkylfurans: the strongest C-X bonds known显示文摘 | SIMMIE J M CURRAN H J | 2009 | The Journal of Physi- cal Chemistry A2009,113,17: | 1 |
| 9 | The influence of fuel structure on combustion as demonstrated by the isomers of heptane: A rapid compression machine study显示文摘 | Silke Emma J Curran Henry J Simmie John M | 2005 | Proceedings of the Combustion Institute2005,30,: | 1 |
| 10 | Ventilator-associated pneumonia显示文摘 | Simmy JP | 2000 | Arch Intern Med2000,160,13: | 1 |
| 11 | Innovation and clustering in the globalized international economy 显示文摘 | Simmie J | 2004 | Urban Studies2004,,41: | 1 |
| 12 | Fournier's gangrene in neonates-differences from that in adults显示文摘 | Simmi K Rattan K N | 2002 | Clinical Pediatrics2002,41,: | 1 |
| 13 | 显示文摘 | Dooley S Curran H J Simmie J M | 2008 | Combust Flame2008,153,: | 1 |
| 14 | Bio-butanol :Combustion properties and detailed chemicalkinetic model 显示文摘 | Black G Curran H J Simmie J M | 2010 | Combustion and Flame2010,157,2: | 1 |
| 15 | Cytokines (IL-6, IL-8, TNF): Early and Reliable Predictors of Severe Acute Pancreatitis显示文摘 | Nakechand Pooran Anant Indaram Pankaj Singh Simmy Bank | 2003 | Journal of Clinical Gastroenterology2003,,3: | 1 |
| 16 | Innovation and Space : A Critical Review of the Literature 显示文摘 | Simmie’J | 2005 | Regional Studies2005,,8: | 1 |
| 17 | The economic resilience of regions: To- wards an evolutionmy approach 显示文摘 | SIMMIE J MARTIN R | 2010 | Cambridge Journal of Regions Eeonomyand Society2010,3,1: | 1 |
| 18 | Innovation and Urban P, egions as National and InternationaZ Nodes for the Transfer and Sharing of Knowledge显示文摘 | Simmie J | 2003 | Regional Studies2003,37,: | 1 |
| 19 | The influence of fuel structure on combustion as demonstrated by the isomers of heptane: a rapid compression machine study显示文摘 | Emma J Silke Henry J Curran John M Simmie | 2005 | Proceedings of the Combustion Institute2005,30,2: | 1 |
| 20 | The economic resilience of re- gions: Towards an evolutionary approach显示文摘 | Simmie J Martin R | 2010 | Cam- bridge Journal of Regions Economy and Society2010,3,1: | 1 |