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17篇 您的检索式:作者名="Simadibrata"
    题名 作者 年代 出处 被引量
1Management of chronic constipation in the elderly显示文摘Kurniawan I Simadibrata M 2011Acta Med Indones2011,43,3:1
2The effect of L-omithine L-aspartateand brnach chain amino acids on encephlaopathy and nutritional status in liver cirrhosis with mlanutrition显示文摘Ndraha S Hasan 1 Simadibrata M 0,,01:1
3The effect of L-omithine Laspartate and branch chain amino acids on encephalopathy and nutritional status in liver cirrhosis with malnutrition显示文摘Ndraha S Hasma I Simadibrata M 2011Acta Med Indones2011,43,1:1
4Management of chronic constipation in the elderly显示文摘Kurniawan I Simadibrata M 2011Acta Med Indones2011,43,3:1
5Side effects of endoscopic variceal ligation by using indonesian endoscopic ligator versus endoscopic variceal sclerotherapy 显示文摘Simadibrata M Syam AF Fauzi A 2011Acta Med Indones2011,43,1:1
6Clinical evaluation of dyspepsia in patients with functional dyspepsia,with the history of Helicobacter pylori eradication therapy in Cipto Mangunkusumo Hospital,Jakarta显示文摘Utia K Syam AF Simadibrata M 2010Acta Med Indones2010,42,2:1
7The effect of L- ornithine L- aspartate and branch chain amino acids on encephalopathy and nutritional status in liver cirrhosis with malnutrition显示文摘NDRAIAA S HASAN I SIMADIBRATA M 2011Acta Med Indones2011,43,1:1
8Clinical evaluation of dyspepsia in patients with functional dyspepsia, with the history of Helicobacter pylori eradication therapy in Cipto Mangunkusumo Hospital, Jakarta显示文摘Utia K Syam AF Simadibrata M 2010Acta Med Indones2010,42,2:1
9New insights on the pathomechanisms of inflammatory bowel disease显示文摘Murdani Abdullah Ari Fahrial Syam Marcellus Simadibrata Jeffri Gunawan Dadang Makmun Abdul Aziz Rani 2013Journal of Digestive Diseases2013,,9:1
10The effect of L-omithine L-aspartate and branch chain amino acids on encephalopathy and nutritional status in liver cirrhosis withmalnutrition显示文摘NDRAHA S HASAN I SIMADIBRATA M 2011Acta Med Indones2011,43,1:1
11Acute pancreatitis in dengue hemorrhagic Fever 显示文摘Simadibrata M 2012Acta Med Indones2012,44,1:1
12Management of chronic constipation in the elderly显示文摘Kumiawan I Simadibrata 2011Acta M ed Indones - Indones2011,43,3:1
13Left lateral decubitus sleeping position is associated with improved gastroesophageal reflux disease symptoms: A systematic review and meta-analysis显示文摘BACKGROUND A limited number of studies have demonstrated that sleeping in the left lateral decubitus(LLD)decreases nocturnal reflux in patients with gastroesophageal reflux disease(GERD)compared to right lateral decubitus(RLD)and supine.AIM This systematic review summarizes the association between sleeping in the LLD position and nocturnal reflux in patients with GERD.METHODS Studies published up to July 17,2023,in MEDLINE,EMBASE,and CENTRAL were searched.Eligible studies were randomized and nonrandomized studies assessing the effect of sleeping in LLD compared to RLD and supine in reducing nocturnal reflux in GERD patients.Outcomes include the acid exposure time(AET)(%time in pH<4),acid clearance time(ACT)(in sec/episode),number of reflux episodes,and improvement in N-GSSIQ scores.RESULTS Two nonrandomized studies showed decreased AET and ACT in LLD sleep position in comparison to RLD(mean difference[MD]-2.03[95%CI:-3.62 to-0.45];-81.84[95%CI:-127.48 to-36.20],respectively)and supine position(MD-2.71[95%CI:-4.34 to-1.09];-74.47[95%CI:-116.26 to-32.69],respectively).There was no difference in AET and ACT between RLD sleep position and supine.Furthermore,one randomized controlled trial investigating the use of electronic sleep positional therapy,which increased the duration of LLD sleep and decreased the duration of RLD sleep compared to sham,showed nocturnal symptoms improvement(improved N-GSSIQ score,increased reflux-free nights,and resolution of nocturnal reflux symptoms).CONCLUSION Current evidence suggests that sleeping on the left side could reduce nocturnal reflux and improve GERD-related quality of life,therefore warranting interventions that promote LLD sleep position.Daniel Martin Simadibrata Elvira Lesmana Bagus Ramasha Amangku Muhammad Prasetio Wardoyo Marcellus Simadibrata 2023World Journal of Clinical Cases2023,11,30:0
14Colorectal cancer patients in a tertiary hospital in Indonesia: Prevalence of the younger population and associated factors显示文摘BACKGROUND An increasing trend in colorectal cancer(CRC)occurring at younger ages has been observed worldwide,even though incidence is declining in the general population.Most currently available guidelines still recommend CRC screening for older populations,despite an alarming rise in early-onset CRC incidence.Risk stratification is necessary to further determine the population most at risk for early-onset CRC.However,epidemiological data on related clinical characteristics and potential risk factors,especially in developing countries,have not been widely reported.AIM To investigate the prevalence,demographics,clinicopathologic features,and associated factors of young-onset CRC patients in a tertiary hospital in Indonesia.METHODS Patients undergoing colonoscopy examination between 2008 and 2019,yielding a diagnosis of CRC were identified from medical records.The subjects were classified into two groups according to their age at diagnosis,namely early-onset(18-49 years old)and late-onset(≥50-years-old).Demographic data,characteristics,and risk factors of both onset age groups were evaluated using the chisquare and Fisher’s exact test.RESULTS Among 495 CRC patients confirmed by histopathology,205(41.4%)were classified as early-onset and 290(58.6%)as late-onset.Most subjects in the earlyonset CRC group were male(53.7%),with 89.8%displaying adenocarcinoma histopathology.A majority(78%)of the early-onset CRC patients had left-sided tumors,with the rectum(41%)and rectosigmoid(17.6%)being the most common sites.Abdominal pain was the most frequent symptom in the early-onset CRC patients(55.6%),which was significantly higher than that in the late-onset CRC patients(43.8%,P<0.05).Early-onset CRC cases were more likely to be underweight(34.6%vs 20.0%,P<0.001)compared to late-onset CRC cases.The proportion of subjects with suspected hereditary nonpolyposis colorectal cancer(HNPCC)was also higher in the early-onset CRC group than in the late-onset age group(9.3%vs 4.1%,P<0.05).However,no difference was observed in the parental or family histories of CRC cases.CONCLUSION Early-onset CRC patients were more likely to have abdominal pain,underweight status,and HNPCC suspicion than late-onset CRC patients.Dadang Makmun Marcellus Simadibrata Murdani Abdullah Ari F Syam Hamzah Shatri Achmad Fauzi KakaRenaldi Hasan Maulahela Amanda P Utari Rabbinu R Pribadi Virly N Muzellina Saskia A Nursyirwan 2021World Journal of Clinical Cases2021,9,32:0
15Vonoprazan-amoxicillin dual regimen with Saccharomyces boulardii as a rescue therapy for Helicobacter pylori:Current perspectives and implications显示文摘Yu et al’s study in the World Journal of Gastroenterology(2023)introduced a novel regimen of Vonoprazan-amoxicillin dual therapy combined with Saccharomyces boulardii(S.boulardii)for the rescue therapy against Helicobacter pylori(H.pylori),a pathogen responsible for peptic ulcers and gastric cancer.Vonoprazan is a potassium-competitive acid blocker renowned for its rapid and long-lasting acid suppression,which is minimally affected by mealtime.Compared to proton pump inhibitors,which bind irreversibly to cysteine residues in the H+/K+-ATPase pump,Vonoprazan competes with the K+ions,prevents the ions from binding to the pump and blocks acid secretion.Concerns with increasing antibiotic resistance,effects on the gut microbiota,patient compliance,and side effects have led to the advent of a dual regimen for H.pylori.Previous studies suggested that S.boulardii plays a role in stabilizing the gut barrier which improves H.pylori eradication rate.With an acceptable safety profile,the dual-adjunct regimen was effective regardless of prior treatment failure and antibiotic resistance profile,thereby strengthening the applicability in clinical settings.Nonetheless,S.boulardii comes in various formulations and dosages,warranting further exploration into the optimal dosage for supplementation in rescue therapy.Additionally,larger,randomized,double-blinded controlled trials are warranted to confirm these promising results.Valerie Josephine Dirjayanto Jessica Audrey Daniel Martin Simadibrata 2024World Journal of Gastroenterology2024,30,10:0
16Gut microbiota diversity and composition in predicting immunotherapy response and immunotherapy-related colitis in melanoma patients:A systematic review显示文摘BACKGROUND Gut microbiome(GM)composition and diversity have recently been studied as a biomarker of response to immune checkpoint blockade therapy(ICB)and of ICBrelated colitis.AIM To conduct a systematic review on the role of GM composition and diversity in predicting response and colitis in patients with melanoma treated with ICB.METHODS The review protocol was registered in PROSPERO:CRD42021228018.From a total of 300 studies,nine studies met inclusion criteria.Two studies were phase I clinical trials,while the remainder were prospective observational studies.All but one study has moderate risk of bias.In addition,we conducted a relevant search by Reference Citation Analysis(RCA)(http://gffzzb1f9d057b5954674sccnu6n09p6wu6ffw.ffgz.tsg.suse.edu.cn).RESULTS Fecal samples enriched in Firmicutes phylum were associated with good response to ICB,whereas the Bacteroidales family was associated with poor response to ICB.Samples with greater GM diversity were associated with more favorable response to ICB[hazard ratio(HR)=3.57,95%confidence interval=1.02-12.52,P<0.05].Fecal samples with a higher abundance in Firmicutes were more susceptible to ICB-related colitis(P<0.01)whereas samples enriched in Bacteroidetes were more resistant to ICB-related colitis(P<0.05).Overall,there was limited concordance in the organisms in the GM identified to be associated with response to ICB,and studies evaluating GM diversity showed conflicting results.CONCLUSION This highlights the need for further prospective studies to confirm whether the GM could be used as a biomarker and potential intervention to modulate ICB response in melanoma patients.Oliver Oey Yu-Yang Liu Angela Felicia Sunjaya Daniel Martin Simadibrata Muhammad Adnan Khattak Elin Gray 2022World Journal of Clinical Oncology2022,13,11:0
17Accuracy of Helicobacter pylori stool antigen for the detection of Helicobacter py/ori infection in dyspeptic patients显示文摘AIM: The premier platinum Helicobacter pylori(H pylori)stool antigen (HpSA) test is an enzyme immunoassay (EIA)that detects an H pylori antigen present in human stools.However, at present there is no uniformity about the cut off level required to consider the test as positive or negative.So we need the cut off level for our local population. The aim of this study was to evaluate the HpSA for the detection of H pylori infection in dyspeptic patients and to determine the sensitivity, specificity of the HpSA test in the diagnosis of H pylori infection, as compared to other standardized diagnostic techniques.METHODS: Sixty-three dyspeptic patients were selected from patients who came to the Division of Gastrointestinal Clinic in Cipto Mangunkusumo Hospital, Jakarta, Indonesia.H pylori infection was confirmed in all patients by histology and rapid urease test (CLO test). Positive results for H pylori were based on positive results from both rapid urea test and microscopic detection of H pylori, Stool specimens were analyzed for H pylori antigen using HpSA immunoassay.RESULTS: A total 63 patients consisted of 31 (49.2%) males and 32 (50.8%) females ranging in ages between 16 and 73 years with a mean age of 42.4±15 years. The mean age of men was 43.2±15.7 years and women was 41.6414.4 years.Endoscopic findings in this study included gastric cancer 1.6%, peptic ulcer 4.8%, duodenal ulcer 7.9%, esophagitis 6.3%, gastritis 77.7%, and gastroduodenitis 4.8%. According to the predefined study criteria, 6 (9.5%) of 63 patients were positive for H pylori. In the diagnosis of infection, the area under the receiver operating characteristic (ROC) curve for the HpSA test was 0.722 (95% CI, 0.518-0.927). Using a cut-off value of 0.274 instead of O. 16 (as recommended by the manufacturer) the sensitivity and the specificity were 66.7% and 78.9% respectively.CONCLUSION: The HpSA stool test, using a cut-off value of 0.274, may be useful for the primary diagnosis of H pylori infection, its specificity is similar to other standard tests but its sensitivity was lower.Ari Fahrial Syam Abdul Aziz Rani Murdani Abdullah C. Manan D. Makmun M. Simadibrata D. Djojoningrat Daldiyono Tadashi Sato 2005World Journal of Gastroenterology2005,11,3:0
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