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27篇 您的检索式:作者名="Shinzeki"
    题名 作者 年代 出处 被引量
1Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitis显示文摘AIM: To examine the effects of anti-high mobility group box 1 (HMGB1) neutralizing antibody in experimental se-vere acute pancreatitis (SAP).METHODS: SAP was induced by creating closed duode-nal loop in C3H/HeN mice. SAP was induced immediately after intraperitoneal injection of anti-HMGB1 neutralizing antibody (200 μg). Severity of pancreatitis, organ injury (liver, kidney and lung), and bacterial translocation to pancreas was examined 12 h after induction of SAP.RESULTS: Anti-HMGB1 neutralizing antibody significant-ly improved the elevation of the serum amylase level and the histological alterations of pancreas and lung in SAP. Anti-HMGB1 antibody also significantly ameliorated the elevations of serum alanine aminotransferase and cre-atinine in SAP. However, anti-HMGB1 antibody worsened the bacterial translocation to pancreas.CONCLUSION: Blockade of HMGB1 attenuated the development of SAP and associated organ dysfunction, suggesting that HMGB1 may act as a key mediator for inflammatory response and organ injury in SAP.Hidehiro Sawa Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Makoto Shinzeki Takahiro Nakajima Yoshikazu Kuroda 2006World Journal of Gastroenterology2006,12,47:45
2Impact of internal biliarydrainage after pancreaticoduodenectomy 显示文摘Fujino Y Matsumoto I Shinzeki M 2009J Hepatobiliary PancreatSurg2009,16,2:1
3Serum immunosuppressive acidic protein levels in patients with severe acute pancreatitis显示文摘Shinzeki M Ueda T Takeyama Y 2007Pancreas2007,35,4:1
4Prediction of early death in severe acute pancreatitis显示文摘Shinzeki M Ueda T 2008Journal of Gastroenterology2008,43,2:1
5Prediction of earlydeath in severe acute pancreatitis 显示文摘Shinzeki M Ueda T Takeyama Y 2008Gastroenterol2008,43,2:1
6Serum immunosuppressive acidic protein levels in patients with severe acute pancreatitis显示文摘Shinzeki M Ueda T Takeyama Y 2007Pancreas2007,35,4:1
7Serum immunosuppres- sive acidic protein levels in patients with severe acute pancreatitis 显示文摘Shinzeki M Ueda T Takeyama Y 2007Pancreas2007,35,4:1
8Prediction of early death in severe acute pancreatitis显示文摘Makoto Shinzeki Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Naoki Matsumura Hidehiro Sawa Takahiro Nakajima Ippei Matsumoto Tsunenori Fujita Tetsuo Ajiki Yasuhiro Fujino Yoshikazu Kuroda 2008Journal of Gastroenterology2008,,:1
9Prediction of early death in severe acute pancreatitis 显示文摘Shinzeki M Ueda T Takeyama Y 2008Gastroenterol2008,43,2:1
10Prediction of early death in severe acute pancreatitis显示文摘Shinzeki M Ueda T 2008J Gastroenterol2008,43,2:1
11Serumimmunosuppressive acidie protein Levels in Patients with severe acute Pancreatitis显示文摘Shinzeki M Ueda T Takeyama Y 0,,04:1
12Plasma tissue factor pathway inhibitor levels in patients with acute pancreatitis显示文摘Takeo Yasuda Takashi Ueda Keiko Kamei Wataru Shinzaki Hidehiro Sawa Makoto Shinzeki Yonson Ku Yoshifumi Takeyama 2009Journal of Gastroenterology2009,,10:1
13Immunosuppression in patients with severe acute pancreatitis显示文摘Takashi Ueda Yoshifumi Takeyama Takeo Yasuda Makoto Shinzeki Hidehiro Sawa Takahiro Nakajima Tetsuo Ajiki Yasuhiro Fujino Yasuyuki Suzuki Yoshikazu Kuroda 2006Journal of Gastroenterology2006,,8:1
14Long-term outcome of severe acute pancreatitis显示文摘Takeo Yasuda Takashi Ueda Yoshifumi Takeyama Makoto Shinzeki Hidehiro Sawa Takahiro Nakajima Yoshikazu Kuroda 2008Journal of Hepato - Biliary - Pancreatic Surgery2008,,4:1
15Prediction of early death in severe acute pancreatitis显示文摘Shinzeki M Ueda T Takeyama Y 2008Gastroenterol2008,43,2:1
16Serum immunosuppressive acidic protein levels in patients with severe acute pancreatitis显示文摘Shinzeki M Ueda T Takeyama Y et a1 2007LPS Pancreas2007,35,4:1
17Treatment strategy against infection: clinical outcome of continuous regional arterial infusion, enteral nutrition, and surgery in severe acute pancreatitis显示文摘Takeo Yasuda Takashi Ueda Yoshifumi Takeyama Makoto Shinzeki Hidehiro Sawa Takahiro Nakajima Ippei Matsumoto Tsunenori Fujita Tetsuya Sakai Tetsuo Ajiki Yasuhiro Fujino Yoshikazu Kuroda 2007Journal of Gastroenterology2007,,8:1
18Prediction of early death in severe acute pancreatitis显示文摘Shinzeki M Ueda T 2008Journal of Gastroenterology2008,43,2:1
19Prediction of early death in severe acute pancreati- tis显示文摘Shinzeki M Ueda T 2008Journal of Gastroenterology2008,43,2:1
20Prediction of early death in severe acute pancreatitis显示文摘Shinzeki M Ueda T Takeyama Y 2008J Gastroenterol2008,43,2:1
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