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| 1 | Discovery of the superlarge gallium ore deposit in Jungar,Inner Mongolia,North China显示文摘Mineralogy and geochemistry of No.6 Coal from the Heidaigou Mine of the Jungar Coalfield of North China were studied using instrumental neu- tron activation analysis,inductively coupled-plasma mass spectroscopy,X-ray fluorescence spectrometry,and scanning electron microscope equipped with an energy-dispersive X-ray spectrometer. The results show that gallium concentration is as high as 44.8 μg·g?1 in the whole coal-channel sample,and varies from 30.1 μg·g?1 to 76.0 μg·g?1 (mean 51.9 μg·g?1) in the main minable benches of No.6 Coal. Such high concentration of Ga in the coal is far higher than the industrial grade (30 μg·g?1). The thickness of the main minable benches accounts for 81.9% of the whole coal bed. The laboratory high-temperature ashes (550℃) of the main minable coal benches also contain a high concentration of Ga,varying from 62.2 μg·g?1 to 178 μg·g?1,with an average of 89.2 μg·g?1. The boehmite significantly enriched in No.6 Coal is the main carrier of the high Ga in the coal. Average concentration of Ga in boehmite is 0.09%. The av- erage content of boehmite is 6.1% in the whole coal and 7.5% in the main minable benches. Boehmite is derived from the bauxite in the weathered crust of the underlying Benxi Formation in the north of the basin during the peat accumulation. The colloidal idrargillite had been shortly transported from the weathered crust to the peat mire,and owing to the compaction of the overlying strata during the peat accumulation and early diagenesis,the idrargillite colloid had begun to be dehydrated,leading to boehmite formation. A pre- liminary estimation showed that the ensured and prospected reserves of Ga in No.6 Coal are up to 6.3 ×104t and 8.57×105t,indicating a superlarge galliumore deposit. The particular paleogeography of the Jungar Coalfield and the peculiar carrier of Ga in coal suggest that this Ga ore deposit is unique in the world. Rare earth elements are also enriched in coal and laboratory ashes. The weighted average concentra- tion of the total rare earth elements is 255 μg·g?1 and 830.36 μg·g?1 in the main minable benches and their laboratory ashes,respectively. Because Al is the main composition of boehmite,aluminum and rare earth elements in No.6 Coal are also the available and valuable resources. | DAI Shifeng REN Deyi LI Shengsheng | 2006 | Chinese Science Bulletin2006，51，18： | 32 |
| 2 | Differences in microstructure and properties between selective laser melting and traditional manufacturing for fabrication of metal parts: A review显示文摘(直线波松) 作为生产技术的添加剂之一,选择激光融化广泛地被调查制作金属部分。在直线波松,部分以一种 layer-by-layer 方式从粉末直接被生产;直线波松也提供几个优点,例如有高三维的精确性的复杂部分的生产,与生产技术的另外的添加剂相比。因此,直线波松能在航空学被使用,航天学,药,并且死并且铸造工业。然而,这种技术不同于传统的方法,例如扔并且前进;例如,前者极大地以产品的微观结构和性质不同。这份报纸通过直线波松在金属材料制造上总结相关研究。基于在 Huazhong 大学 Sci 技术完成的一个工作,快速的 Manuf。中心(HUST-RMC ) 并且与在其它描述的特征相比,直线波松的报导研究,微观结构,性质,维的精确性,和应用被介绍。 | Bo SONG Xiao ZHAO Shuai LI Changjun HAN Qingsong WEI Shifeng WEN Jie LIU Yusheng SHI | 2015 | Frontiers of Mechanical Engineering2015，10，2： | 26 |
| 3 | Breast cancer development and progression:Risk factors,cancer stem cells,signaling pathways,genomics,and molecular pathogenesis显示文摘As the most commonly occurring cancer in women worldwide,breast cancer poses a formidable public health challenge on a global scale.Breast cancer consists of a group of biologically and molecularly heterogeneous diseases originated from the breast.While the risk factors associated with this cancer varies with respect to other cancers,genetic predisposition,most notably mutations in BRCA1 or BRCA2 gene,is an important causative factor for this malignancy.Breast cancers can begin in different areas of the breast,such as the ducts,the lobules,or the tissue in between.Within the large group of diverse breast carcinomas,there are various denoted types of breast cancer based on their invasiveness relative to the primary tumor sites.It is important to distinguish between the various subtypes because they have different prognoses and treatment implications.As there are remarkable parallels between normal development and breast cancer progression at the molecular level,it has been postulated that breast cancer may be derived from mammary cancer stem cells.Normal breast development and mammary stem cells are regulated by several signaling pathways,such as estrogen receptors(ERs),HER2,and Wnt/b-catenin signaling pathways,which control stem cell proliferation,cell death,cell differentiation,and cell motility.Furthermore,emerging evidence indicates that epigenetic regulations and noncoding RNAs may play important roles in breast cancer development and may contribute to the heterogeneity and metastatic aspects of breast cancer,especially for triple-negative breast cancer.This review provides a comprehensive survey of the molecular,cellular and genetic aspects of breast cancer. | Yixiao Feng Mia Spezia Shifeng Huang Chengfu Yuan Zongyue Zeng Linghuan Zhang Xiaojuan Ji Wei Liu Bo Huang Wenping Luo Bo Liu Yan Lei Scott Du Akhila Vuppalapati Hue H.Luu Rex C.Haydon Tong-Chuan He Guosheng Ren | 2018 | Genes & Diseases2018，5，2： | 24 |
| 4 | Sedimentary Record of the Planation Surface in the Hoh Xil Region of the Northern Tibet Plateau显示文摘Miocene marl is the most widespread Tertiary stratigraphic record in the northern Tibet Plateau, termed the Wudaoliang Group in the Hoh Xil region and the correlative Suonahu Formation in the Qiangtang region. The uniform marl overlies red beds of the Eocene-Oligocene Fenghuoshan Group. The Wudaoliang Group is generally 100-400 m thick, but the thickest strata are 700-1300 m, located in the Haidinghu (Maiding Lake) and Tuotuohe (Tuotuo River) regions respectively. Based on observations from eight measured sections and outcrops, the thin-bedded marl, which varies in colour from grey-white to light brown-grey, is explained as a large-scale or serial lacustrine deposit stretching throughout northern Tibet.The Wudaoliang Group commonly crops out on geographic lowland at an average elevation of 4600 m above sea level within the mountain chains, showing concordant summit levels, e.g. the Fenghuoshan and Bairizhajia Mountains. These mountains with a flat ridge are considered to be remains of the | YI Haisheng WANG Chengshan LIU Shun LIU Zhifei WANG Shifeng | 2000 | Acta Geologica Sinica(English Edition)2000，74，4： | 22 |
| 5 | CO_2 capture from binary mixture via forming hydrate with the help of tetra-n-butyl ammonium bromide显示文摘Hydrate formation rate and separation effect on the capture of CO2 from binary mixture via forming hydrate with 5 wt% tetra-n-butyl ammonium bromide (TBAB) solution were studied. The results showed that the induction time was 5 min, and the hydrate formation process finished in 1 h at 4.5 °C and 4.01 MPa. The hydrate formation rate constant reached the maximum of 1.84×10-7 mol2/(s J) with the feed pressure of 7.30 MPa. The CO2 recovery was about 45% in the feed pressure range from 4.30 to 7.30 MPa. Under the feed pressure of 4.30 MPa, the maximum separation factor and CO2 concentration in hydrate phase were 7.3 and 38.2 mol%, respectively. The results demonstrated that TBAB accelerated hydrate formation and enriched CO2 in hydrate phase under the gentle condition. | Shifeng Li Shuanshi Fan Jingqu Wang Xuemei Lang Deqing Liang | 2009 | Journal of Natural Gas Chemistry2009，18，1： | 22 |
| 6 | Climate change and its driving effect on the runoff in the "Three-River Headwaters" region显示文摘在长江的 headwater 分区在三河的 Headwaters 区域和 Zhimenda 的观察流量数据基于 降水和 12 个气象学的车站的温度数据,在在 Lancang 河的 headwater 分区的黄河和 Changdu 的 headwater 分区的 Tangnaihai 在时期期间 19652004 ,这份报纸分析 降水的趋势,温度,流量深度并且借助于 Mann-Kendall-Sneyers 执行意义测试顺序Makkink 模型被使用计算潜在的蒸发。降水和潜在的蒸发驾驶的流量模型被开发,对由气候变化的流量的影响在不同情形下面被模仿。结果在时期期间显示出那 19652004 三河的 Headwaters 区域的温度正在增加,三个水文学车站的流量正在减少,他们俩在 1994 有突然的变化,当没有重要趋势变化时,发生在降水身上。流量模型建议降水在流量深度上有积极效果,当潜在的蒸发起一个否定作用时。Lancang 河的流量深度上的潜在的蒸发的影响被发现是在三条河里重要;并且黄河的是最少。情形分析的结果显示尽管降水和潜在的蒸发相对在流量上有积极、否定的效果,处于特定的状况的流量深度上的单个效果的波动的特征被代表。 | ZHANG Shifeng HUA Dong MENG Xiujing ZHANG Yongyong | 2011 | Journal of Geographical Sciences2011，21，6： | 16 |
| 7 | Coal facies evolution of the main minable coal-bed in the Heidaigou Mine, Jungar Coalfield, Inner Mongolia, northern China显示文摘The No. 6 Coal-bed from the Heidaigou Mine, Jungar Coalfield, Inner Mongolia is a super-large Ga deposit. The dominant carrier of Ga is boehmite in coal. The study of coal facies may provide genetic enrichment information of Ga and its carrier (boehmite) in the Ga deposit. On the basis of study on coal petrology and mineralogy, it was found that the No. 6 Coal-bed from the Heidaigou Mine of Jungar was enriched in inertinites and the microlitho-types were dominated by clarodurite. The maceral morphological features and association indicate that the coal-bed was formed in a dry sedimentary environment or in a periodic dry sedimentary environment caused by the alternating variations of groundwater level. The optimum conditions for the enrichment of Ga and its particular carrier (boehmite) were dominated by four transitional conditions: (1) the upper delta plain which was the transitional zone between alluvial and lower delta plains, (2) the transitional zone between the dry and wet forest swamps, being slightly apt to the dry one, (3) the transitional tree density between the thick and loose ones, and (4) the low moor that was the transitional zone between two high moors during peat accumulation. | DAI ShiFeng REN DeYi LI ShengSheng ZHAO Lei ZHANG Yong | 2007 | Science China Earth Sciences2007，50，z2： | 14 |
| 8 | Runoff variation and its response to climate change in the Three Rivers Source Region显示文摘在三次规模(非充满的季节,泛滥的季节和年度时期) 的流量在 Tangnaihai 从 1958 ~ 2005 被模仿并且测试(黄河来源区域:YeSR ) , Zhimenda (长江来源区域:YaSR ) 并且 Changdu (Lancang 河来源区域:LcSR ) 由水文学建模,趋势察觉和比较分析。另外,在三个插头的从 2010 ~ 2039 的未来流量变化在 CSIRO 和 NCAR 气候模型和气候的影响的 A1B 和 B1 情形被分析变化被测试。结果证明年度、非充满的季节流量在 YeSR 显著地减少了,它减少了黄河的水分泌物到中流并且下游地,并且在黄河盆加强了水缺乏,但是另外的二个区域不在最后 48 年里是统计上重要的。与在基线(1990 年代) 的流量相比,在 YeSR 的流量将在下列 30 年(20102039 ) 里减少,特别在非充满的季节。因此黄河盆的在中流并且下游地的水缺乏将连续地是严肃的。在 YaSR 的流量将增加,特别在泛滥的季节,这样洪水控制状况将是严重的。在 LcSR 的流量将也比当前的流量大,并且年度、充满的季节流量不显著地变化,当在非充满的季节的流量变化是不明确的时。它将在 CSIRO 模型的 B1 情形显著地增加,但是在 NCAR 模型的 B1 情形显著地减少。而且,到气候变化的最敏感的区域是 YaSR,由 YeSR 和 LcSR 列在后面。 | ZHANG Yongyong ZHANG Shifeng ZHAI Xiaoyan XlA Jun | 2012 | Journal of Geographical Sciences2012，22，5： | 14 |
| 9 | Magnetostratigraphy of the Zanda basin in southwest Tibet Plateau and its tectonic implications显示文摘The Zanda basin is one of the very important basins at the north slope of the Himalaya Range. Thus the study of the basin strata will provide critical information about the tectonic evolution of the Himalayan Orogenic Belt. 268 oriented block samples were collected in the 750-m-thick sections of the Zanda ba- sin. The characteristic remanent magnetization (ChRM) was isolated that decays linearly to the origin between 500oC and 690oC for most studied samples. An age range of 9.5―2.6 Ma was estimated from the correlation between our observed polarity column and the Geomagnetic Polarity Time Scale (GPTS). The age of the Zanda basin does not support the models that the South Tibetan Detach system (STDS) is one of the basin controlling faults. Given the sedimentological features in the basin and the tectonic features at the north edge of the basin, the Zanda basin was a half graben that was possibly controlled by the Karakorum fault on the northeast. | WANG ShiFeng ZHANG WeiLin FANG XiaoMin DAI Shuang Oliver KEMPF | 2008 | Chinese Science Bulletin2008，53，9： | 12 |
| 10 | In situ preparation of g-C3N4/Bi4O5I2 complex and its elevated photoactivity in Methyl Orange degradation under visible light显示文摘A graphite carbon nitride(g-C3N4)modified Bi4O5I2 composite was successfully prepared insitu via the thermal treatment of a g-C3N4/Bi OI precursor at 400°C for 3 hr.The as-prepared g-C3N4/Bi4O5I2 showed high photocatalytic performance in Methyl Orange(MO)degradation under visible light.The best sample presented a degradation rate of 0.164 min^-1,which is 3.2 and 82 times as high as that of Bi4O5I2 and g-C3N4,respectively.The g-C3N4/Bi4O5I2 was characterized by X-ray powder diffractometer(XRD),scanning electron microscopy(SEM),transmission electron microscopy(TEM),Raman,X-ray photoelectron spectroscopy(XPS),ultraviolet-visible diffuse reflectance spectra(DRS),electrochemical impedance spectroscopy(EIS)and transient photocurrent response in order to explain the enhanced photoactivity.Results indicated that the decoration with a small amount of g-C3N4 influenced the specific surface area only slightly.Nevertheless,the capability for absorbing visible light was improved measurably,which was beneficial to the MO degradation.On top of that,a strong interaction between g-C3N4 and Bi4O5I2 was detected.This interplay promoted the formation of a favorable heterojunction structure and thereby enhanced the charge separation.Thus,the g-C3N4/Bi4O5I2 composite presented greater charge separation efficiency and much better photocatalytic performance than Bi4O5I2.Additionally,g-C3N4/Bi4O5I2 also presented high stability.·O2^- and holes were verified to be the main reactive species. | Zhe Feng Lin Zeng Qingle Zhang Shifeng Ge Xinyue Zhao Hongjun Lin Yiming He | 2020 | Journal of Environmental Sciences2020，32，1： | 12 |
| 11 | Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference显示文摘Mesenchymal stem cells(MSCs)are multipotent stem cells and capable of differentiating into multiple cell types including osteoblastic,chondrogenic and adipogenic lineages.We previously identified BMP9 as one of the most potent BMPs that induce osteoblastic differentiation of MSCs although exact molecular mechanism through which BMP9 regulates osteogenic differentiation remains to be fully understood.Here,we seek to develop a recombinant adenovirus system to optimally silence mouse BMP9 and then characterize the important role of BMP9 in osteogenic differentiation of MSCs.Using two different siRNA bioinformatic prediction programs,we design five siRNAs targeting mouse BMP9(or simB9),which are expressed under the control of the converging H1 and U6 promoters in recombinant adenovirus vectors.We demonstrate that two of the five siRNAs,simB9-4 and simB9-7,exhibit the highest efficiency on silencing exogenous mouse BMP9 in MSCs.Furthermore,simB9-4 and simB9-7 act synergistically in inhibiting BMP9-induced expression of osteogenic markers,matrix mineralization and ectopic bone formation from MSCs.Thus,our findings demonstrate the important role of BMP9 in osteogenic differentiation of MSCs.The characterized simB9 siRNAs may be used as an important tool to investigate the molecular mechanism behind BMP9 osteogenic signaling.Our results also indicate that recombinant adenovirus-mediated expression of siRNAs is efficient and sustained,and thus may be used as an effective delivery vehicle of siRNA therapeutics. | Shujuan Yan Ruyi Zhang Ke Wu Jing Cui Shifeng Huang Xiaojuan Ji Liping An Chengfu Yuan Cheng Gong Linghuan Zhang Wei Liu Yixiao Feng Bo Zhang Zhengyu Dai Yi Shen Xi Wang Wenping Luo Bo Liu Rex C.Haydon Michael J.Lee Russell R.Reid Jennifer Moriatis Wolf Qiong Shi Hue H.Luu Tong-Chuan He Yaguang Weng | 2018 | Genes & Diseases2018，5，2： | 8 |
| 12 | Orbital Forcing and Sea-Level Changes in the Earliest Triassic of the Meishan Section,South China显示文摘The Earliest Triassic Yinkeng Formation is exposed at the well-known Meishan Section,South China,which contains the Global Stratotype of Section and Point(GSSP)for the PermianTriassic boundary(PTB).It records centimeter-scale rhythmic alternations comprised mainly by marlstone and limestone.Seven types of couplet embedded in five types of bundles were recognized based on occurrence and thickness of the lithologic units,suggesting that their formation was controlled by cyclic processes.The various orders of cycles observed correlate well with other Early Triassic counterparts recorded in South China.Here,we present new cyclostratigraphic results based on lithologic thickness and relative carbonate content of the Yinkeng Formation.Power spectra of carbonate content show that the ratio of major wavelengths recognized throughout the formation is similar to that of the 100kyr short eccentricity,33 kyr obliquity,and 21 kyr precession cycles,indicating that astronomical signals are recorded in the Earliest Triassic rhythmic succession.Consistence between pronounced lithologic rhythmicity and sea-level changes obtained from Fischer plots indicates that high-frequency climatic cycles may have driven sea-level changes immediately after the PTB mass extinction.Furthermore,the 4th-order sea-level changes interpreted from the sedimentary record match well with 100kyr short eccentricity component of carbonate content,reflecting that the 100 kyr short eccentricityinduced climate changes may have likely controlled the deposition of 4th-order sequences recognized from rhythmic successions. | Shifeng Tian Zhong-Qiang Chen Chunju Huang | 2014 | Journal of Earth Science2014，25，1： | 6 |
| 13 | CoN_(x)C active sites-rich three-dimensional porous carbon nanofibers network derived from bacterial cellulose and bimetal-ZIFs as efficient multifunctional electrocatalyst for rechargeable Zn–air batteries显示文摘In this work, a CoNxC active sites-rich three-dimensional porous carbon nanofibers network derived from bacterial cellulose and bimetal-ZIFs is prepared via a nucleation growth strategy and a pyrolysis process.The material displays excellent electrocatalytic activity for the oxygen reduction reaction, reaching a high limiting diffusion current density of -7.8 mA cm^(-2), outperforming metal–organic frameworks derived multifunctional electrocatalysts, and oxygen evolution reaction and hydrogen evolution reaction with low overpotentials of 380 and 107 mV, respectively. When the electrochemical properties are further evaluated, the electrocatalyst as an air cathode for Zn-air batteries exhibits a high cycling stability for63 h as well as a maximum power density of 308 mW cm^(-2), which is better than those for most Zn-air batteries reported to date. In addition, a power density of 152 mW cm^(-2) is provided by the solid-state Zn-air batteries, and the cycling stability is outstanding for 24 h. The remarkable electrocatalytic properties are attributed to the synergistic effect of the 3 D porous carbon nanofibers network and abundant inserted CoNxC active sites, which enable the fast transmission of ions and mass and simultaneously provide a large contact area for the electrode/electrolyte. | Wenming Zhang Jingjing Chu Shifeng Li Yanan Li Ling Li | 2020 | Journal of Energy Chemistry2020，29，12： | 6 |
| 14 | Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS:Rg1 excretion in rat bile, urine and feces显示文摘Ginsenoside Rg1(Rg1), the major effective component of ginseng, has been shown to have multiple bioactivities, but low oral bioavailability. The aim of this study was to develop a simple, sensitive and rapid high performance liquid chromatography–tandem mass spectrometry(LC–MS/MS) method, which could be used to validate and quantify the concentrations of Rg1 and its metabolites in Sprague-Dawley rat bile,urine, and feces after oral administration(25 mg/kg). Calibration curves offered satisfactory linearity(r40.995)within the determined ranges. Both intra-day and inter-day variances were less than 15%, and the accuracy was within 80–120%. The excretion recoveries of Rg1, ginsenoside Rh1(Rh1), and protopanaxatriol(Ppt) in bile,urine, and feces combined were all greater than 70%. The fecal excretion recoveries of Rg1, Rh1, and Ppt were40.11%, 22.19%, and 22.88%, respectively, whereas 6.88% of Rg1 and 0.09% of Rh1 were excreted in bile.Urinary excretion accounted for only 0.04% of Rg1. In conclusion, the observed excretion profiles for Rg1 and its metabolites after oral administration are helpful for understanding the poor oral bioavailability of Rg1 and will aid further investigations of Rg1 as a pharmacologically active component. | Chiyu He Ru Feng Yupeng Sun Shifeng Chu Ji Chen Chao Ma Jie Fu Zhenxiong Zhao Min Huang Jiawen Shou Xiaoyang Li Yuzhu Wang Jinfeng Hu Yan Wang Juntian Zhang | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 6 |
| 15 | Structure change of 430 stainless steel in the heating process显示文摘The microstructure analysis was employed for the ferritic stainless steel(SUS430)with the carbon content from 0.029wt% to 0.100wt% under the simulated heating process condition.The higher carbon sample(430H)contains the duplex phase micro- structure at the temperature of 1150℃;on the other hand,the lower carbon content sample(430L)does not touch two phase area even at the temperature of 1450℃and has the single phase ferritic microstructure.The carbon content need be well controlled for the 430 ferritic stainless steel since it can significantly affect the heating process curve,and the heating process may not be done in the two phase area due to the uncontrolled carbon content.With the low carbon content and the proper soaking time,the grain size is not sensitive to the heating process temperature and the soaking time.In the present heat treatment experiments,the soaking time is about 10 min,and the processing parameters can be chosen according to the requirement of the gross energy,the efficiency and the continual forming. | Xinzhong Liu Jingtao Han Wanhua Yu Shifeng Dai | 2008 | Journal of University of Science and Technology Beijing2008，15，1： | 6 |
| 16 | A new single-cell protein from Clostridium autoethanogenum as a functional protein for largemouth bass(Micropterus salmoides)显示文摘Clostridium autoethanogenum protein(CAP)is a new single-cell protein source originating from inactivated bacteria.An in vitro digestion experiment and an 8-wk growth experiment were conducted to evaluate the molecular weight distribution of the CAP hydrolysate,and the effects of dietary CAP levels on the growth performance,plasma parameters,hepatic and intestinal health,and the diversity of gutadherent microbiota of largemouth bass(Micropterus salmoides).The fish(initial body weight of 47.99±0.01 g)were fed diets where CAP gradually replaced 0%(CAP0),12.5%(CAP12.5),25%(CAP25),37.5%(CAP37.5)and 50%(CAP50)of low-temperature steam dried anchovy fish meal(LTFM)in the diet.Results showed that the content of peptides below 1,000 Da in the CAP hydrolysate(0.56 mg/mL)was higher than that of the LTFM hydrolysate(0.48 mg/mL).Dietary CAP inclusion had no negative effect on growth performance,while whole-body lipid content significantly reduced in the CAP25 and CAP50 groups(P<0.05).The plasma alanine aminotransferase activities and triglyceride concentrations in the CAP inclusion groups were significantly lower than those in the CAP0 group(P<0.05).The plasma aspartate aminotransferase activity was significantly reduced in the CAP37.5 group(P<0.05).The richness and diversity of the gut-adhesive microbiota and the proportion of Clostridium sensu stricto 12 in the CAP50 group were significantly higher than those in the CAP0 group(P<0.05).Dietary CAP inclusion inhibited inflammatory responses by down-regulating the mRNA levels of interleukin 1b(IL1b),IL10 and transforming growth factor b1(P<0.05)in the liver.The mRNA levels of acetyl-CoA carboxylase 1 were significantly down-regulated in the CAP12.5,CAP25 and CAP37.5 groups(P<0.05),while that of fatty acid synthase was significantly down-regulated in the CAP50 group(P<0.05).These results demonstrate that dietary CAP inclusion could improve the hepatic and intestinal health of largemouth bass,and can be helpful to further develop CAP as a functional feed ingredient. | Shifeng Ma Xiaofang Liang Pei Chen Jie Wang Xu Gu Yuchang Qin Christophe Blecker Min Xue | 2022 | Animal Nutrition2022，，3： | 6 |
| 17 | Laplacian Speech Model and Soft Decision Based MMSE Estimator for Noise Power Spectral Density in Speech Enhancement显示文摘The estimation of noise Power spectral density(PSD) is a very crucial issue for speech enhancement as a result of its significant effect on the quality and intelligibility of the enhanced speech. Most of the existing estimators for noise PSD try to employ Gaussian speech priors, which, however, have been proven inconsistent with the reality. We derived an effective solution to this problem of estimating noise PSD in the Minimum mean square error(MMSE) sense when the speech component is modeled by a Laplacian distribution. Meanwhile, the soft decision technique instead of the hard Voice activity detection(VAD) is evolved into our algorithm, which can automatically makes the estimation unbiased without requiring a bias compensation. The performance of the proposed method is tested by several objective and subjective measures under various stationary and nonstationary noise environments. The results confirm that our method achieves good performance for all the noise conditions and Signalnoise-ratio(SNR) settings. | OU Shifeng SONG Peng GAO Ying | 2018 | Chinese Journal of Electronics2018，27，6： | 5 |
| 18 | sTLR4/MD-2 complex inhibits colorectal cancer migration and invasiveness in vitro and in vivo by IncRNA H19 down-regulation显示文摘 | Weijun Liang Yan Zou Fengxian Qin Jifei Chen Junyi Xu Shifeng Huang Jingfan Chen Shengming Dai | 2017 | Acta Biochimica et Biophysica Sinica2017，49，11： | 5 |
| 19 | Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes(imPODs)显示文摘Glomerular podocytes are highly specialized epithelial cells and play an essential role in establishing the selective permeability of the glomerular filtration barrier of kidney.Maintaining the viability and structural integrity of podocytes is critical to the clinical management of glomerular diseases,which requires a thorough understanding of podocyte cell biology.As mature podocytes lose proliferative capacity,a conditionally SV40 mutant tsA58-immortalized mouse podocyte line(designated as tsPC)was established from the Immortomouse over 20 years ago.However,the utility of the tsPC cells is hampered by the practical inconvenience of culturing these cells.In this study,we establish a user-friendly and reversibly-immortalized mouse podocyte line(designated as imPOD),on the basis of the tsPC cells by stably expressing the wildtype SV40 T-antigen,which is flanked with FRT sites.We show the imPOD cells exhibit long-term high proliferative activity,which can be effectively reversed by FLP recombinase.The imPOD cells express most podocyte-related markers,including WT-1,Nephrin,Tubulin and Vinculin,but not differentiation marker Synaptopodin.The imPOD cells do not form tumor-like masses in vivo.We further demonstrate that TGFb1 induces a podocyte injury-like response in the FLP-reverted imPOD cells by suppressing the expression of slit diaphragm-associated proteins P-Cadherin and ZO-1 and upregulating the expression of mesenchymal markers,a-SMA,Vimentin and Nestin,as well as fibrogenic factors CTGF and Col1a1.Collectively,our results strongly demonstrate that the newly engineered im-POD cells should be a valuable tool to study podocyte biology both under normal and under pathological conditions. | Xinyi Yu Liqun Chen Ke Wu Shujuan Yan Ruyi Zhang Chen Zhao Zongyue Zeng Yi Shu Shifeng Huang Jiayan Lei Xiaojuan Ji Chengfu Yuan Linghuan Zhang Yixiao Feng Wei Liu Bo Huang Bo Zhang Wenping Luo Xi Wang Bo Liu Rex C.Haydon Hue H.Luu Tong-Chuan He Hua Gan | 2018 | Genes & Diseases2018，5，2： | 5 |
| 20 | Energy Analysis of a CPG-controlled Miniature Robotic Fish显示文摘 | Junzhi Yu Shifeng Chen Zhengxing Wu Xingyu Chen Ming Wang | 2018 | Journal of Bionic Engineering2018，15，2： | 5 |
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