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| 1 | Brain dopaminergic system changes in drug addiction:a review of positron emission tomography findings显示文摘Dopamine(DA)is considered crucial for the rewarding effects of drugs of abuse,but its role in addiction remains unclear.Positron emission tomography(PET)is the first technology used for in vivo measurement of components of the dopaminergic system in the human brain.In this article,we review the major findings from PET imaging studies on the involvement of DA in drug addiction,including presynaptic DA synthesis,vesicular monoamine transporter 2,the DA transporter,and postsynaptic DA receptors.These results have corroborated the role of DA in addiction and increased the understanding of its underlying mechanisms. | Haifeng Hou Chunyan Wang Shaowei Jia Shu Hu Mei Tian | 2014 | Neuroscience Bulletin2014,30,5: | 3 |
| 2 | Correction: The NAC transcription factor ClNAC68 positively regulates sugar content and seed development in watermelon by repressing ClINV and ClGH3.6显示文摘In this article 1,author name Yanping Wang was incorrectly tagged as corresponding author.Prof.Wang should be the co-first author,instead of the corresponding author.The original article has been corrected. | Jinfang Wang Yanping Wang Jie Zhang Yi Ren Maoying Li Shaowei Tian Yongtao Yu Yi Zuo Guoyi Gong Haiying Zhang Shaogui Guo Yong Xu | 2021 | Horticulture Research2021,8,1: | 2 |
| 3 | Microstructure and Properties of an Al 6061/Galvanized Plate Fabricated by CMT Welding显示文摘Aluminum alloy 6061 was welded with zinc coated low carbon steel by cold metal transfer (CMT).The microstructure composition,morphology and growth process of the welding joint and the HAZ were researched.The weld area on the side of the galvanized steel sheet mainly contains Fe2Al5.And on the side of the aluminum alloy substrate,it is mainly filled with a needle-like FeAl3.At the same time,Al8Fe2Si is formed at the edge of FeAl3.The zinc-rich region on the side of the aluminum alloy mainly contains an aluminum-zinc solid solution and an aluminum-zinc co-crystal,and the current size had no significant effect on the type and morphology of the compounds produced in the interface layer. | 张琪 张培磊 于治水 YAN Hua SHI Haichuan WU Di LI Shaowei TIAN Yingtao | 2020 | Journal of Wuhan University of Technology(Materials Science)2020,35,5: | 2 |
| 4 | DSP & FPGA-based control architecture for a highly integrated robot hand with enhanced impedance performance显示文摘 | 吴克 Lan Tian Chen Yangbin Liu Yiwei Jin Minghe Fan Shaowei Chen Zhaopeng Liu Hong | 2010 | High Technology Letters2010,16,2: | 1 |
| 5 | A Modelling Study on PM_(2.5)-Related Health Impacts from Climate Change and Air Pollution Emission Control--China,2010s and 2040s显示文摘What is already known about this topic?Climate change and air pollution are two important environmental issues in China.It is important to investigate particulate matter with aerodynamic diameter less than 2.5μm(PM2.5)-related health impacts from climate change and air pollution emission control.What is added by this report?Deaths and years of life lost related to PM2.5 would increase in climate change scenario,although emission control would outweigh the influence of climate change.What are the implications for public health practice?More targeted actions should be taken to meet challenges of exacerbated PM2.5 pollutions and its health impacts related to climate change in the future. | Jing Huang Heng Tian Jiawei Wang Teng Yang Yiran Peng Shaowei Wu Tzung-May Fu Guoxing Li | 2021 | China CDC weekly2021,3,23: | 0 |
| 6 | The NAC transcription factor CINAC68 positively regulates sugar content and seed development in watermelon by repressing CIINV and CIGH3.6显示文摘NAC(NAM,ATAF1/2,and CUC2)transcription factors play important roles in fruit ripening and quality.The watermelon genome encodes 80 NAC genes,and 21 of these NAC genes are highly expressed in both the flesh and vascular tissues.Among these genes,CINAC68 expression was signi fi cantly higher in flesh than in rind.However,the intrinsic regulatory mechanism of CINAC68 in fruit ripening and quality is still unknown.In this study,we found that ClNAC68 is a transcriptional repressor and that the repression domain is located in the C-terminus.Knockout of CINAC68 by the CRISPR-Cas9 system decreased the soluble solid content and sucrose accumulation in mutant flesh.Development was delayed,germination was inhibited,and the IAA content was signi ficantly decreased in mutant seeds.Transcriptome analysis showed that the invertase gene CUNV was the only gene involved in sucrose metabolism that was upregulated in mutant flesh,and expression of the indole-3-acetic acid-amido synthetase gene CIGH3.6 in the IAA signaling pathway was also induced in mutant seeds.EMSA and dual-luciferase assays showed that CINAC68 directly bound to the promoters of CUNV and CIGH3.6 to repress their expression.These results indicated that CINAC68 positively regulated sugar and IAA accumulation by repressing CUNV and CIGH3.6.Our findings provide new insights into the regulatory mechanisms by which NAC transcription factors affect fruit quality and seed development. | Jinfang Wang Yanping Wang Jie Zhang Yi Ren Maoying Li Shaowei Tian Yongtao Yu Yi Zuo Guoyi Gong Haiying Zhang Shaogui Guo Yong Xu | 2021 | Horticulture Research2021,8,1: | 0 |
| 7 | Quantification/mechanism of interfacial interaction modulated by electric potential in aqueous salt solution显示文摘With the development of surface and interface science and technology,methods for the online modulation of interfacial performance by external stimuli are in high demand.Switching between ultra-low and high friction states is a particular goal owing to its applicability to the development of precision machines and nano/micro-electromechanical systems.In this study,reversible switching between superlubricity and high friction is realized by controlling the electric potential of a gold surface in aqueous salt solution sliding against a SiO_(2) microsphere.Applying positive potential results creates an ice-like water layer with high hydrogen bonding and adhesion at the interface,leading to nonlinear high friction.However,applying negative potential results in free water on the gold surface and negligible adhesion at the interface,causing linear ultra-low friction(friction coefficient of about 0.004,superlubricity state).A quantitative description of how the external load and interfacial adhesion affected friction force was developed,which agrees well with the experimental results.Thus,this work quantitatively reveals the mechanism of potential-controlled switching between superlubricity and high-friction states.Controlling the interfacial behavior via the electric potential could inspire novel design strategies for nano/micro-electromechanical and nano/micro-fluidic systems. | Shaowei LI Pengpeng BAI Yuanzhe LI Noshir SPESIKA Yonggang MENG Liran MA Yu TIAN | 2021 | Friction2021,9,3: | 0 |
| 8 | Novel CD123×CD33 bicistronic chimeric antigen receptor(CAR)-T therapy has potential to reduce escape from single-target CAR-T with no more hematotoxicity显示文摘Dear Editor,Antigen escape is responsible for resistance[1]or disease relapse[2]from single-target chimeric antigen receptor(CAR)-T therapy.Dual-target CAR-T therapy has the potential to overcome the escape problem.However,the efficacy and safety assessment of dual-target CAR-T therapy in treating acute myeloid leukemia(AML)need further investigation.Tandem CAR-T therapy has been widely used in research and clinic.However,clustering of two connected single-chain variable fragments(scFvs)[3]and the inappropriate conjugation distance[4]pose a risk of damaging tandem CAR-T cells’function. | Zhenzhen Wang Yang Lu Yu Liu Junli Mou Xiaoyu Liu Manling Chen Ying Wang Yingxi Xu Qing Rao Haiyan Xing Kejing Tang Zheng Tian Bing Wang Wei Qi Min Wang Shaowei Qiu Dongsheng Xiong Jianxiang Wang | 2023 | Cancer Communications2023,43,10: | 0 |
| 9 | Improvement of hydrogen permeation barrier performance by iron sulphide surface films显示文摘Fe–S compounds with hexagonal crystal structure are potential hydrogen permeation barrier during H2S corrosion. Hexagonal system Fe–S films were prepared on carbon steel through corrosion and CVD deposition, and the barrier effect of different Fe–S films on hydrogen permeation was tested using electrochemical hydrogen permeation method. After that, the electrical properties of Fe–S compound during phase transformation were measured using thermoelectric measurement system. Results show that the mackinawite has no obvious barrier effect on hydrogen penetration, as a p-type semiconductor, and pyrrhotite (including troilite) has obvious barrier effect on hydrogen penetration,as an n-type semiconductor. Hydrogen permeation tests showed peak permeation performance when the surface was deposited with a continuous film of pyrrhotite (Fe_(1–x)S) and troilite. The FeS compounds suppressed hydrogen permeation by the promotion of the hydrogen evolution reaction, semiconducting inversion from p-to n-type, and the migration of ions at the interface. | Pengpeng Bai Shaowei Li Jie Cheng Xiangli Wen Shuqi Zheng Changfeng Chen Yu Tian | 2023 | International Journal of Minerals,Metallurgy and Materials2023,30,9: | 0 |