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| 1 | Establishment and application of distant hybridization technology in fish显示文摘Hybridization is widely used. However, for a long time, systematic theories and technologies related to hybridization in fish have been lacking. In this study, through long-term systematic research, we investigated and obtained the main rules regarding inheritance and reproduction related to fish distant hybridization. Furthermore, we established one-step and multistep breeding technologies that were suitable for interspecific hybridization and intraspecific hybridization. Simultaneously, we used these two breeding technologies to produce a batch of diploid fish lineages and tetraploid fish lineages and improved fishes. In addition, we widely discuss the methods, technologies and results of hybridization breeding, referring to the domestic and foreign literature on fish hybridization. We hope that this paper will be beneficial for the research and application of fish hybrid breeding. | Shi Wang Chenchen Tang Min Tao Qinbo Qin Chun Zhang Kaikun Luo Rurong Zhao Jing Wang Li Ren Jun Xiao Fangzhou Hu Rong Zhou Wei Duan Shaojun Liu | 2019 | Science China(Life Sciences)2019，62，1： | 6 |
| 2 | A pair of transposon-derived proteins function in a histone acetyltransferase complex for active DNA demethylation显示文摘Transposons 被 epigenetic 机制通常包括 DNA methylation 使沉默。这里,我们识别了一双先驱导出 transposon 的蛋白质(HDP ) , HDP1 和 HDP2,在 Arabidopsis 的反沉默因素。hdp1 和 hdp2 异种显示了 transgenes 和某 transposons 的提高的 silencing。种系发生的分析表明 HDP1 和 HDP2 分别地从先驱编码 transposon 的 transposase 和 DNA 有约束力的蛋白质被共同驯养。HDP1 在原子核与 HDP2 交往,类似于他们的 transposon 对应物。而且, HDP1 和 HDP2 与组成在 DNA demethylation 工作的 histone acetyltransferase 建筑群的 IDM1, IDM2, IDM3 和 MBD7 被联系。HDP2 和 methyl-DNA-binding 蛋白质 MBD7 分享普通 genomic 绑定地点的一个大集合,显示他们联合决定 histone acetyltransferase 建筑群的目标特性。因此,我们的数据表明 HDP1 和 HDP2 组成被招募了到 histone acetyltransferase 建筑群阻止 DNA hypermethylation 和 epigenetic silencing 的一个功能的模块。 | Cheng-Guo Duan Xingang Wang Shaojun Xie Li Pan Daisuke Miki Kai Tang Chuan-Chih Hsu Mingguang Lei Yingli Zhong Yueh-Ju Hou ZhijuanWang Zhengjing Zhang Satendra K Mangrauthia Huawei Xu Heng Zhang Brian Dilkes W Andy Tao Jian-Kang Zhu | 2017 | Cell Research2017，27，2： | 6 |
| 3 | The Structure of Departure Process and Optimal Control Strategy N^* for Geo/G/1 Discrete-Time Queue with Multiple Server Vacations and Min(N, V)-Policy显示文摘This paper considers the departure process and the optimal control strategy for a discretetime Geo/G/1 queueing model in which the system operates under the control of multiple server vacations and Min(N, V)-policy. Using the law of total probability decomposition, the renewal theory and the probability generating function technique, the transient and the steady-state probabilities that the server is busy at any epoch n^+ are derived. The authors also obtain the explicit expression of the probability generating function for the expected number of departures occurring in the time interval (0^+, n^+] from any initial state. Meanwhile, the relationship among departure process, server's state process and service renewal process in server busy period is found, which shows the special structure of departure process. Especially, some corresponding results of departure process for special discrete-time queues are directly gained by our results. Furthermore, the approximate expansion for calculating the expected number of departures is presented. In addition, some other important performance measures,including the expected length of server busy period, server's actual vacation period and busy cycle period etc., are analyzed. Finally, some numerical results are provided to determine the optimum value N*for minimizing the system cost under a given cost structure. | LAN Shaojun TANG Yinghui | 2017 | Journal of Systems Science & Complexity2017，30，6： | 6 |
| 4 | MCM-36 zeolites tailored with acidic ionic liquid to regulate adsorption properties of isobutane and 1-butene显示文摘Adsorption properties of an adsorbent or a catalyst towards adsorbates are crucial in the process of adsorption separation or catalytic reaction. Surface morphology and structure of adsorbents have a significant impact on the adsorption properties. In this study, a novel acidic ionic liquid, 1-butyl-3-(triethoxysilylpropyl)imidazolium hydrogen sulfate(i.e., [BTPIm][HSO_4]), was synthesized and subsequently grafted onto the MCM-36 zeolite for the regulation of its adsorption properties towards isobutane and 1-butene. The resultant [BTPIm][HSO_4]-immobilized MCM-36(i.e., MCM-36-IL) was characterized by FT-IR, XPS, XRD, SEM, TG/DTG and N_2 adsorption–desorption measurement. It was found that the specific surface area, micropore volume and mesopore volume of the MCM-36 support underwent a reduction upon the immobilization of ionic liquid,while the surface density of acid increased from 0.0014 to 0.0035 mmol·m^(-2). The adsorption capacity of isobutane and 1-butene on the MCM-36-IL was determined by a static volumetric method. Results demonstrated that the interaction between isobutane and MCM-36-IL was enhanced and the interaction between 1-butene and MCM-36-IL was reduced. As a result, a tunable adsorption ratio of isobutane/1-butene on MCM-36 was achieved.With the increase in surface density of acid and the tunable adsorption ratio of isobutane and 1-butene on the functionalized MCM-36, the acidic ionic liquid-immobilized zeolites are beneficial to obtain an improved reaction yield and a prolonged catalyst life in the reactions catalyzed by solid acid. | Hongxia Li Tao Zhang Shaojun Yuan Shengwei Tang | 2016 | Chinese Journal of Chemical Engineering2016，24，12： | 5 |
| 5 | Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma显示文摘Osteosarcoma is the most common primary bone sarcoma that mostly occurs in young adults. The causes of osteosarcoma are heterogeneous and still not fully understood. Identification of novel, important oncogenic factors in osteosarcoma and development of better, effective therapeutic approaches are in urgent need for better treatment of osteosarcoma patients. In this study, we uncovered that the oncogene MYC is significantly upregulated in metastastic osteosarcoma samples. In addition, high MYC expression is associated with poor survival of osteosarcoma patients. Analysis of MYC targets in osteosarcoma revealed that most of the osteosarcoma super enhancer genes are bound by MYC. Treatment of osteosarcoma cells with super enhancer inhibitors THZ1 and JQ1 effectively suppresses the proliferation, migration, and invasion of osteosarcoma cells. Mechanistically,THZ1 treatment suppresses a large group of super enhancer containing MYC target genes including CDK6 and TGFB2. These findings revealed that the MYC-driven super enhancer signaling is crucial for the osteosarcoma tumorigenesis and targeting the MYC/super enhancer axis represents as a promising therapeutic strategy for treatment of osteosarcoma patients. | Demeng Chen Zhiqiang Zhao Zixin Huang Du-Chu Chen Xin-Xing Zhu Yi-Ze Wang Ya-Wei Yan Shaojun Tang Subha Madhavan Weiyi Ni Zhan-peng Huang Wen Li Weidong Ji Huangxuan Shen Shuibin Lin Yi-Zhou Jiang | 2018 | Bone Research2018，6，2： | 5 |
| 6 | The LRXs-RALFs-FER module controls plant growth and salt stress responses by modulating multiple plant hormones显示文摘Salt stress is a major environmental factor limiting plant growth and productivity.We recently discovered an important new salt tolerance pathway,where the cell wall leucine-rich repeat extensins LRX3/4/5,the RAPID ALKALINIZATION FACTOR(RALF)peptides RALF22/23 and receptor-like kinase FERONIA(FER)function as a module to simultaneously regulate plant growth and salt stress tolerance.However,the intracellular signaling pathways that are regulated by the extracellular LRX3/4/5-RALF22/23-FER module to coordinate growth,cell wall integrity and salt stress responses are still unknown.Here,we report that the LRX3/4/5-RALF22/23-FER module negatively regulates the levels of jasmonic acid(JA),salicylic acid(SA)and abscisic acid(ABA).Blocking JA pathway rescues the dwarf phenotype of the lrx345 and fer-4mutants,while disruption of ABA biosynthesis suppresses the salt-hypersensitivity of these mutants.Many salt stress-responsive genes display abnormal expression patterns in the lrx345 and fer-4 mutants,as well as in the wild type plants treated with epigallocatechin gallate(EGCG),an inhibitor of pectin methylesterases,suggesting cell wall integrity as a critical factor that determines the expression pattern of stress-responsive genes.Production of reactive oxygen species(ROS)is constitutively increased in the lrx345 and fer-4mutants,and inhibition of ROS accumulation suppresses the salt-hypersensitivity of these mutants.Together,our work provides strong evidence that the LRX3/4/5-RALF22/23-FER module controls plant growth and salt stress responses by regulating hormonal homeostasis and ROS accumulation. | Chunzhao Zhao Wei Jiang Omar Zayed Xin Liu Kai Tang Wenfeng Nie Yali Li Shaojun Xie Yuan Li Tiandan Long Linlin Liu Yingfang Zhu Yang Zhao Jian-Kang Zhu | 2021 | National Science Review2021，8，1： | 3 |
| 7 | ReSSIM:a mixed-level simulator for dynamic coarse-grained reconfigurable processor显示文摘This paper proposes a mixed-level simulator for dynamic coarse-grained reconfigurable processor(CGRP),called ReSSIM(reconfigurable system simulation implementation mechanism),and the corresponding simulation tool-chain,including task compiler,profiler and debugger.A generic modeling methodology supporting convenient extension of on-chip modules is also proposed.In order to explore the details of the interested modules while maintaining reasonable simulation speed,RCA(reconfigurable computing array),the key reconfigurable device in ReSSIM,is modeled on cycle-accurate level,while the other modules are modeled on transaction level.The typical parameters of RCA are scalable and adjustable,which helps the architects to explore the massive details of the reconfigurable device.Experiment shows that simulation speedup achieved ranges from 9.26× to 18.39× compared with VCS(Synopsys verilog compiler simulator) when running three computingintensive kernel tasks of H.264 decoding algorithm-IDCT(inverse discrete cosine transform),deblocking and MC-chroma(motion compensation).Simulation speed for a set of real applications,such as MPEG4,G.729 and EFR,is 35× slower than the corresponding native executions(i.e.measured from the real chip).And the relative simulation errors are 11% less than the measured IPC(instructions per cycle) of the real chip. | LIU LeiBo JIA Wen YIN ShouYi WANG Dong SUN GuanYi TANG Eugene WEI ShaoJun | 2013 | Science China(Information Sciences)2013，56，6： | 2 |
| 8 | Regulation of isobutane/1-butene adsorption behaviors on the acidic ionic liquids-functionalized MCM-22 zeolite显示文摘The adsorption ratio of isobutane/1-butene on the catalyst surface is one of the most important factors for the C_4 alkylation process. Regulation of isobutane/1-butene adsorption ratio on the zeolite-supported acid catalyst is a big challenge for catalyst preparation. To regulate the isobutane/1-butene adsorption ratio, four types of ionic liquid(i.e., IL) with different alkyl chain lengths and different acid group numbers were synthesized and were subsequently immobilized onto the MCM-22 zeolite. The as-synthesized IL-immobilized MCM-22(i.e., MCM-22-IL)was characterized by FTIR, TGA, BET, XPS and XRD, and their adsorption capacities and adsorption molar ratios of isobutane to 1-butene(I/O) were investigated to correlate with surface features of MCM-22-IL. Results showed that the immobilization of ILs led to a decrease of specific surface area and pore volume. But the surface density of acid groups was increased and the adsorption molar ratio of isobutane/1-butene(I/O) was significantly improved by the immobilization of ionic liquids. The adsorption molar ratio of I/O is substantially improved from 0.75 to above 0.9 at 300 kPa upon immobilizing ILs. Although the alkyl chain length of ILs was found to have little effect on the adsorption molar ratio of I/O, the increase of acid group numbers led to a dramatic decrease in the adsorption I/O ratio. The results illustrated that immobilizing ionic liquids is an effective way to modify the textural, chemical and morphological properties of MCM-22. Accordingly, the immobilization of ionic liquids provides a novel and a feasible way to regulate the adsorption I/O ratio on an adsorbent or a solid catalyst. | Keting Jin Tao Zhang Shaojun Yuan Shengwei Tang | 2018 | Chinese Journal of Chemical Engineering2018，26，1： | 2 |
| 9 | Electrochemistry of heteropolyanions in coulombically linked self- assembled monolayers显示文摘 | Liu Shaoqin Tang Zhiyong Dong Shaojun | 1998 | Journal of Electroanalytical Chemistry1998，458，1： | 1 |
| 10 | An improved Z- source inverter 显示文摘 | TANG Yu XIE Shaojun ZHANG Chaohua | 2011 | IEEE Transactions on Power Electronics2011，26，12： | 1 |
| 11 | Evaluations ofcurrent control in weak grid case for grid-connectedLCL-filtered inverter显示文摘 | Xu Jinming Xie Shaojun Tang Ting | 2013 | IET Power Electron2013，6，2： | 1 |
| 12 | One-step hydrogenation/esterification activity enhancement over bifunctional mesoporous organic-inorganic hybrid silicas显示文摘 | Tang Yang Miao Shaojun Liu Yemo | 2013 | Topics in Catalysis2013，56，181920： | 1 |
| 13 | Pulse width modulation of Z-source inverters with inductor current ripple显示文摘 | Tang Yu Xie Shaojun Ding Jiudong | 2014 | IEEE Transa Industrial Electronics2014，61，1： | 1 |
| 14 | Abnormal meiosis in fertile and sterile triploid cyprinid fish显示文摘Meiosis is the key process for producing mature gametes. A natural fertile triploid Carassius auratus population(3nDTCC) and an artificially derived sterile triploid crucian carp(3nCC) have been previously observed, providing suitable model organisms for investigating meiosis characteristics in triploid fish. In the present study, the microstructures and ultrastructures of spermatogenesis were studied in these fishes. Td T-mediated d UTP nick end labeling detection was performed to investigate the apoptosis of spermatocytes. Fluorescence in situ hybridization was employed to trace chromatin pairing. In addition, the m RNA expressions of cell cycle-related genes(i.e., cell division control 2 and cell cycle protein B) were determined by quantitative realtime polymerase chain reaction to illustrate the molecular mechanism of abnormal meiosis in the 3nCC. The results showed that the 3nCC undergoes an irregular prophase I, with the chromosomes distributed in a unipolar radial manner and exhibiting partial pairing, hindered metaphase I, and degenerated cells in the subsequent stages. Meanwhile, the 3nDTCC presented a relatively regular meiotic prophase I with complete conjugate chromosome pairs and chromosomes distributed along the karyotheca,which were presented as a ring structure by slicing. Only the spreads with 130–150 irregular chromosomes can be easily detected in the 3nDTCC, suggesting that it may undergo an abnormal metaphase I. This study provides new insights into the meiosis of fertile and sterile triploid cyprinid fish. | Chun Zhang Qi Li La Zhu Wangchao He Conghui Yang Hui Zhang Yu Sun Luojing Zhou Yuandong Sun Shurun Zhu Chang Wu Min Tao Yi Zhou Rurong Zhao Chenchen Tang Shaojun Liu | 2021 | Science China(Life Sciences)2021，64，11： | 1 |
| 15 | Improved Z-source inverter with reduced Z-source capacitor voltage stress and soft-start capability显示文摘 | Yu Tang Shaojun Xie | 2009 | IEEE Transactions on Power Electronics2009，24，2： | 1 |
| 16 | Influence of alemtuzumab on the intestinal Paneth cells and microflora in macaques显示文摘 | Qiurong Li Qiang Zhang Chenyang Wang Chun Tang Yanmei Zhang Shaojun Jiang Ning Li Jieshou Li | 2010 | Clinical Immunology2010，，3： | 1 |
| 17 | Active damping-based control for grid-connected LCL- filtered inverter with injected grid current feedback only显示文摘 | Xu Jinming Xie Shaojun Tang Ting | 2014 | IEEE Transactions on Industrial Electronics2014，61，9： | 1 |
| 18 | R esearch on low -order c u rre n t harm onics re je ctions fo r grid -con necte d L C L -filte re d inverters 显示文摘 | X u J in m in g Tang T in g X ie Shaojun | | IE T Power E le c tro n ic s0，7，5： | 1 |
| 19 | Improved Z-source inverter with reduced Z-source capacitor voltage stress and soft-start capability 显示文摘 | Tang Yu Xie Shaojun Zhang Chaohua | 2009 | IEEE Transactions on Power Electronics2009，24，2： | 1 |
| 20 | Improved Z-source inverter with reduced Z-source capacitor voltage stress and soft -start capability显示文摘 | TANG Yu XIE Shaojun ZHANG Chaohua | 2009 | IEEE Transactions on Power Electronics2009，24，2： | 1 |
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