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| 1 | A new component maps correction method using variable geometric parameters显示文摘Accurate engine performance models are important for model-based performance evaluation of aero engine.The accuracy of the model often depends on engine component maps,so there is a need for a method that can accurately correct the component maps of the model over a wide range.In this paper,a new method for modifying component maps is proposed,this method combines the correction of the scaling factors with the solution process of the off-design working point,and uses the adjustment of the variable geometric parameters of the engine to change the position of the working line,in order to obtain more correction results and guarantee high accuracy in a wider range.The method is validated by taking the main fan of the Adaptive Cycle Engine(ACE),an ideal power unit for a new generation of multi-purpose and ultra-wide working range aircraft,as an example.The results show that the maximum error between the corrected component maps and the target maps is less than 1%.New possibility for more precise component maps can be realized in this paper. | Shaochen LI Hailong TANG Min CHEN | 2021 | Chinese Journal of Aeronautics2021，34，4： | 1 |
| 2 | Contemporary epidemiology of gout and hyperuricemia in community elderly in B eijing显示文摘 | Xiaolan Lu Xiaoxia Li Yi Zhao Zheng Zheng Shaochen Guan Piu Chan | 2014 | Int J Rheum Dis2014，，4： | 1 |
| 3 | Plasmid-Mediated Quinolone Resistance Genes and Antibiotic Residues in Wastewater and Soil Adjacent to Swine Feedlots: Potential Transfer to Agricultural Lands显示文摘 | Li Juan Wang Thanh Shao Bing Shen Jianzhong Wang Shaochen Wu Yongning | 2012 | EN2012，，8： | 1 |
| 4 | Effects of electromagnetic radiation on spatial memory and synapses in rat hippocampal CA1显示文摘In this study,we investigated the effects of mobile phone radiation on spatial learning,reference memory,and morphology in related brain regions.After the near-field radiation(0.52-1.08 W/kg) was delivered to 8-week-old Wistar rats 2 hours per day for 1 month,behavioral changes were examined using the Morris water maze.Compared with the sham-irradiated rats,the irradiated rats exhibited impaired performance.Morphological changes were investigated by examining synaptic ultrastructural changes in the hippocampus.Using the physical dissector technique,the number of pyramidal neurons,the synaptic profiles,and the length of postsynaptic densities in the CA1 region were quantified stereologically.The morphological changes included mitochondrial degenerations,fewer synapses,and shorter postsynaptic densities in the radiated rats.These findings indicate that mobile phone radiation can significantly impair spatial learning and reference memory and induce morphological changes in the hippocampal CA1 region. | Yuhong Li Changhua Shi Guobing Lu Qian Xu Shaochen Liu | 2012 | Neural Regeneration Research2012，7，16： | 1 |
| 5 | High-capacity adsorption of Cr(VI) from aqueous solution using a hierarchical porous carbon obtained from pig bone显示文摘 | Shaochen Wei Dongtian Li Zhe Huang Yaqin Huang Feng Wang | 2013 | Bioresource Technology2013，，： | 1 |
| 6 | High-capacity adsorption of Cr(Ⅵ) from aqueous solution using a hierarchical porous carbon obtained from pig bone 显示文摘 | Shaochen Wei Dongtian Li Zhe Huang | 2013 | Biore- source Technology2013，134，： | 1 |
| 7 | Analytical Analysis of a Circular PZT Actuator for Valveless Micropumps显示文摘 | Li Shifeng Chen Shaochen | 2003 | Sensors and Actuators A2003，104，9： | 1 |
| 8 | DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation显示文摘Background: Environmental pollution induces oxidative stress and apoptosis in mammalian oocytes, which can cause defects in reproduction;however, the molecular regulation of oxidative stress in oocytes is still largely unknown. In the present study, we identified that dynamin-related protein 1(DRP1) is an important molecule regulating oocyte mitochondrial function and preventing oxidative stress/apoptosis. DRP1 is a member of the dynamin GTPase superfamily localized at the mitochondrial-endoplasmic reticulum interaction site, where it regulates the fission of mitochondria and other related cellular processes.Results: Our results show that DRP1 was stably expressed during different stages of porcine oocyte meiosis, and might have a potential relationship with mitochondria as it exhibited similar localization. Loss of DRP1 activity caused failed porcine oocyte maturation and cumulus cell expansion, as well as defects in polar body extrusion.Further analysis indicated that a DRP1 deficiency caused mitochondrial dysfunction and induced oxidative stress,which was confirmed by increased reactive oxygen species levels. Moreover, the incidence of early apoptosis increased as detected by positive Annexin-V signaling.Conclusions: Taken together, our results indicate that DRP1 is essential for porcine oocyte maturation and that a DRP1 deficiency could induce mitochondrial dysfunction, oxidative stress, and apoptosis. | Haolin Zhang Zhennan Pan Jiaqian Ju Chunhua Xing Xiaohan Li Mengmeng Shan Shaochen Sun | 2021 | Journal of Animal Science and Biotechnology2021，12，1： | 1 |
| 9 | Aluminum exposure impairs oocyte quality via subcellular structure disruption and DNA damage-related apoptosis in mice显示文摘Aluminum(Al)can lead to an exposure of creature in varieties ways for its universality,and it could disturb normal physiological metabolism,with the damage to multisystem including reproduction.Since the oocyte quality is critical for female reproduction,we inspected the toxicity of Al on mouse oocyte maturation.We constructed in vitro exposure mouse model,and we found that 5 mmol/L Al had adverse effects on oocyte maturation by impairing organelle and cytoskeleton.Aberrant spindle and misaligned chromosomes which might be considered to be caused by elevated levels of acetylation,as well as abnormal distribution of actin dynamics could hinder normal meiosis of oocytes.Organelle dysfunction indicated that Al affected proteins synthesis,transport and digestion,which would further damage oocyte maturation.In order to explore the mechanism of Al toxicity,our further investigation demonstrated that Al caused mitochondrial dysfunction and imbalance calcium homeostasis,resulting in limited energy supply.Moreover,high level of reactive oxygen species,DNA damage and apoptosis caused by oxidative stress were also the manifestation of Al toxicity on oocytes.In conclusion,our study provided the evidence that Al exposure affected oocyte quality through its effects on spindle organization,actin dynamics,organelle function and the induction of DNA damage-related apoptosis with mouse model. | Hongge Li Jingcai Liu Weihua Nong Mengying Shen Sheng Dou Shaochen Sun Junli Wang | 2024 | Journal of Environmental Sciences2024，，5： | 0 |
| 10 | Induced Pib Expression and Resistance to Magnaporthe grisea are Compromised by Cytosine Demethylation at Critical Promoter Regions in Rice显示文摘Pib is a well-characterized rice blast-resistance gene belonging to the nucleotide binding site (NBS) and leucine-rich repeat (LRR) superfamily.Expression of Pib was low under non-challenged conditions,but strongly induced by the blast-causing fungal pathogen Magnaporthe grisea,thereby conferring resistance to the pathogen.It is generally established that cytosine methylation of the promoter-region often plays a repressive role in modulating expression of the gene in question.We report here that two critical regions of the Pib promoter were heavily CG cytosine-methylated in both cultivars studied.Surprisingly,induced expression of Pib by M.grisea infection did not entail its promoter demethylation,and partial demethylation by 5-azacytidine-treatment actually reduced Pib expression relative to wildtype plants.Accordingly,the blast disease-resistance was compromised in the 5-azaC-treated plants relative to wild-type.In contrast,the disease susceptibility was not affected by the 5-azaC treatment in another two rice cultivars that did not contain the Pib gene,ruling out effects of other R genes and non-specific genotoxic effects by the drug-treatment as a cause for the compromised Pib-conditioned blast-resistance.Taken together,our results suggest that promoter DNA methylation plays a novel enhancing role in conditioning high-level of induced expression of the Pib gene in times of M.grisea infection,and its conferred resistance to the pathogen. | Yuan Li Qiong Xia Hongping Kou Dan Wang Xiuyun Lin Ying Wu Chunming Xu Shaochen Xing Bao Liu | 2011 | Journal of Integrative Plant Biology2011，53，10： | 0 |
| 11 | Two distinct roles of Al_(2)Sm and Al_(11)Sm_(3) phases on the corrosion behavior of the magnesium alloy Mg-5Sm-xAl显示文摘The roles of Al11Sm3 and Al_(2)Sm phases on microstructure evolution,mechanical properties and corrosion behavior of the Mg-5Sm-x Al system was investigated.The results showed that adding Al to Mg–5Sm binary alloy brought two Al–Sm phases,Al11Sm3 and Al_(2)Sm,which had two distinct roles regarding the microstructure evolution,mechanical properties and corrosion behavior of the Mg-Sm-Al alloy.Al11Sm3 produced a strong galvanic couple with the Mg matrix,and significantly accelerated the corrosion.The Al_(2)Sm particles promoted heterogeneous nucleation and refined the grains,which increased the tensile strength and ductility.Both types of Al–Sm particles provided strengthening effect for the alloy.With higher Al contents,Al2Sm formed an Al oxide protective surface layer and increased corrosion resistance. | Xingrui Chen Qi Zou Qichi Le Shaochen Ning Chenglu Hu Xiaoqiang Li Anrej Atrens | 2021 | Progress in Natural Science:Materials International2021，31，4： | 0 |
| 12 | Structures and Nonlinear Optical Properties of Lithium-adsorbed Polycyclic π-Conjugated Pentacene Systems显示文摘 | LI Shaochen YU Guangtao CHEN Wei HUANG Xuri | 2015 | Chemical Research in Chinese Universities2015，31，2： | 0 |
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