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| 1 | BK nephropathy in the native kidneys of patients with organ transplants: Clinical spectrum of BK infection显示文摘Nephropathy secondary to BK virus, a member of the Papoviridae family of viruses, has been recognized for some time as an important cause of allograft dysfunction in renal transplant recipients. In recent times, BK nephropathy(BKN) of the native kidneys has being increasingly recognized as a cause of chronic kidney disease in patients with solid organ transplants, bone marrow transplants and in patients with other clinical entities associated with immunosuppression. In such patients renal dysfunction is often attributed to other factors including nephrotoxicity of medications used to prevent rejection of the transplanted organs. Renal biopsy is required for the diagnosis of BKN. Quantitation of the BK viral load in blood and urine are surrogate diagnostic methods. The treatment of BKN is based on reduction of the immunosuppressive medications. Several compounds have shown antiviral activity, but have not consistently shown to have beneficial effects in BKN. In addition to BKN, BK viral infection can cause severe urinary bladder cystitis, ureteritis and urinary tract obstruction as well as manifestations in other organ systems including the central nervous system, the respiratory system, the gastrointestinal system and the hematopoietic system. BK viral infection has also been implicated in tumorigenesis. The spectrum of clinical manifestations from BK infection and infection from other members of the Papoviridae family is widening. Prevention and treatment of BK infection and infections from other Papovaviruses are subjects of intense research. | Darlene Vigil Nikifor K Konstantinov Marc Barry Antonia M Harford Karen S Servilla Young Ho Kim Yijuan Sun Kavitha Ganta Antonios H Tzamaloukas | 2016 | World Journal of Transplantation2016，6，3： | 4 |
| 2 | Prolonged hypernatremia triggered by hyperglycemic hyperosmolar state with coma: A case report显示文摘A man with past lithium use for more than 15 years, but off lithium for two years and not carrying the diagnosis of diabetes mellitus or nephrogenic diabetes insipidus(NDI), presented with coma and hyperglycemic hyperosmolar state(HHS). Following correction of HHS, he developed persistent hypernatremia accompanied by large volumes of urine with low osmolality and no response to desmopressin injections. Urine osmolality remained < 300 m Osm/kg after injection of vasopressin. Improvement in serum sodium concentration followed the intake of large volumes of water plus administration of amiloride and hydrochlorothiazide. Severe hyperglycemia may trigger symptomatic lithium-induced NDI years after cessation of lithium therapy. Patients with newonset diabetes mellitus who had been on prolonged lithium therapy in the past require monitoring of their serum sodium concentration after hyperglycemic episodes regardless of whether they do or do not carry the diagnosis of NDI. | Darlene Vigil Kavitha Ganta Yijuan Sun RichardⅠDorin Antonios H Tzamaloukas Karen S Servilla | 2015 | World Journal of Nephrology2015，4，2： | 3 |
| 3 | Long term ecological research and information management显示文摘 | William K. Michener John Porter Mark Servilla Kristin Vanderbilt | 2010 | Ecological Informatics2010，，1： | 1 |
| 4 | Age-related blood pressure patterns and blood pressure variability among hemodialysis patients显示文摘 | Rohrscheib MR Myers OB Servilla KS | 2008 | Am Soc Nephrol2008，3，5： | 1 |
| 5 | Osmotic myelinolysis following chronic hyponatremia corrected at an overall rate consistent with current rcommendations显示文摘 | Dellabarca C Servilla K Hert B | 2005 | Int Urol Nephrol2005，37，： | 1 |
| 6 | Type 1 diabetes is associated with alexithymia in nondepressed, non-mentally ill diabetic patients: a case-control study 显示文摘 | Adeniyi M Sun Y Servilla KS | 2009 | J Psychosom Res2009，67，4： | 1 |
| 7 | Advanced wasting in peritoneal dialysis patients显示文摘AIM To identify patients with end-stage renal disease treated by peritoneal dialysis(PD) who had zero body fat(BF) as determined by analysis of body composition using anthropometric formulas estimating body water(V) and to compare nutritional parameters between these patients and PD patients whose BF was above zero.METHODS Body weight(W) consists of fat-free mass(FFM) andBF.Anthropometric formulas for calculating V allow the calculation of FFM as V/0.73,where 0.73 is the water fraction of FFM at normal hydration.Wasting from loss of BF has adverse survival outcomes in PD.Advanced wasting was defined as zero BF when V/0.73 is equal to or exceeds W.This study,which analyzed 439 PD patients at their first clearance study,used the Watson formulas estimating V to identify patients with V_(Watson)/0.73 ≥ W and compared their nutritional indices with those of PD patients with V_(Watson)/0.73 < W.RESULTS The study identified at the first clearance study two male patients with V_(Watson)/0.73 ≥ W among 439 patients on PD.Compared to 260 other male patients on PD,the two subjects with advanced wasting had exceptionally low body mass index and serum albumin concentration.The first of the two subjects also had very low values for serum creatinine concentration and total(in urine and spent peritoneal dialysate) creatinine excretion rate while the second subject had an elevated serum creatinine concentration and high creatinine excretion rate due,most probably,to non-compliance with the PD prescription.CONCLUSION Advanced wasting(zero BF) in PD patients,identified by the anthropometric formulas that estimate V,while rare,is associated with indices of poor somatic and visceral nutrition. | Zhi Xu Glen H Murata Robert H Glew Yijuan Sun Darlene Vigil Karen S Servilla Antonios H Tzamaloukas | 2017 | World Journal of Nephrology2017，6，3： | 1 |
| 8 | Age - related blood pressure parrerns and blood pressure variabiliy among hemodialysis patients 显示文摘 | Rohrscheib MR Myers OB Servilla KS | 2008 | Clin J Am Soc Nephrol2008，3，5： | 1 |
| 9 | A metadatadriven approach to loading and querying heterogeneous scientific data显示文摘 | Ben Leinfelder Jing Tao Duane Costa Matthew B.Jones Mark Servilla Margaret O'Brien Chad Burt | | 0，，01： | 1 |
| 10 | Osmotic myelinolysis following chronic hyponatremia corrected at an overall rate consistent with current recommendations 显示文摘 | CASEY DELLABARCA KAREN S SERVILLA BLAINEHERT | 2005 | International Urology and Nephrology2005，37，： | 1 |
| 11 | Tubulointerstitial nephritis and uveitis syndrome:use of gallium scintigraphy in its diagnosis and treatment显示文摘 | Helms E Servilla KS Hartshorne MF | 2005 | Int Urol Nephrol2005，37，： | 1 |
| 12 | Agerelated Blood Pres- sure Patterns and Blood Pressure Variability among Hemodialysis Pa- tients显示文摘 | Rohrscheib RM Myers OB Servilla KS | 2008 | Clin J Am Soc Nephrol2008，3，5： | 1 |
| 13 | Long term ecological research and information management显示文摘 | MICHENER WILLIAM K PORTER JOHN SERVILLA MARK | 2011 | Ecological Informatics2011，6，1： | 1 |
| 14 | Anemia Management and Association of Race With Mortality and Hospitalization in a Large Not-for-Profit Dialysis Organization显示文摘 | Karen S. Servilla Ajay K. Singh William C. Hunt Antonia M. Harford Dana Miskulin Klemens B. Meyer Edward J. Bedrick Mark R. Rohrscheib Antonios H. Tzamaloukas H. Keith Johnson Philip G. Zager | 2009 | American Journal of Kidney Diseases2009，，3： | 1 |
| 15 | Type 1 diabetes is assoei ated with alexithymia in nondepressed, non-mentally ill di- abetic patients : a ease-control study显示文摘 | Adeniyi M Sun Y Servilla KS | 2009 | J Psyehosom Res2009，67，4： | 1 |
| 16 | Age-related blood pressure patterns and blood pressure variability among hemodialysis patients 显示文摘 | Mark R Orrin B Servilla KS | 2008 | Clin J Am Soc Nephrol2008，3，5： | 1 |
| 17 | Tubulointerstitial nephritis and uveitis syndrome:use of gallium scintigraphy in its diagnosis and treatment显示文摘 | Helms E Servilla KS Hartshorne MF | 2005 | Int Urol Nephrol2005，37，1： | 1 |
| 18 | Type 1 diabetes is associated with alexithymia in nondepressed, non-mentally ill diabetic patients: a case -control study 显示文摘 | Adeniyi M Sun Y Servilla K S | 2009 | J Psychosom Res2009，67，4： | 1 |
| 19 | Anemia management and association of race with mortality and hospitalization in a large not-for-profit dialysis organization显示文摘 | Servilla K S Singh A K Hunt W C Harford A M Miskulin D Meyer K B | 2009 | Am J Kidney Dis2009，54，： | 1 |
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