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| 1 | 利用二维应变定量检测整体和局部心肌功能:在肥厚型心肌病中的应用显示文摘OBJECTIVES: Recently, a novel method to measure strain from standard two-dimensional images has been developed. Our goal was to characterize global and regional systolic function abnormalities using this technique in patients with hypertrophic cardiomyopathy(HCM). BACKGROUND: Strain has been proposed as a sensitive tool to detect early systolic function abnormalities in HCM. However, the clinical application of conventional Doppler-derived strain has been limited by poor reproducibility and angle dependency. METHODS: Echocardiographic examinations were performed in 26 patients with nonobstructive HCM and 45 healthy subjects. Using a dedicated software package, bidimensional acquisitions were analyzed to measure longitudinal and transverse strain in apical views and circumferential and radial strain in parasternal short-axis view. RESULTS: Despite apparently normal left ventricular systolic function, all components of strain were significantly reduced in HCM. Average longitudinal, transverse, circumferential, and radial strain in patients with HCM and controls were -15.1± 6.2% versus -20.3± 5.6% , 23.3± 17.0% versus 27.2± 14.9% ,-16.8± 7.1% versus 19.6± 5.2% , and 25.2± 13.9% versus 36.8± 17.2% , respectively(all p< 0.001). In patients with asymmetrical HCM, longitudinal septal strain was significantly lower than for other left ventricular segments combined:-9.2± 4.7% versus-12.7± 7.1% (p=0.001). Average interobserver and intraobserver variabilities were 11% and 11.3% , respectively. CONCLUSIONS: Two-dimensional strain is a new simple, rapid, and reproducible method to measure different components of systolic strain. This technique identified early abnormalities in patients with HCM that have apparently normal left ventricular systolic function. | Serri K. Reant P. Lafitte M. S. Lafitte 孙凯 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，8： | 3 |
| 2 | Lateral flow of African mantle below the nearby Tyrrhenian plate: geochemical evidence显示文摘 | Trua T Serri G Marani M P | 2003 | Terra Nova2003，15，6： | 1 |
| 3 | Cognitive, metacognitive, and social/affective strategies in listening com- prehension and their relationships with individual differences 显示文摘 | Serri F Boroujeni A J & Hesabi A | 2012 | Theory and Practice in Language Studies2012，，2： | 1 |
| 4 | Developing cross-cultural skills of international business students:an experiment显示文摘 | Sizoo Steve Serrie Hendrick | 2004 | Journal of Instructional Psychology2004，31，2： | 1 |
| 5 | Somatostatin analogue, octreotide, reduces increased glomerularfiltration rate and kidney size in insulin-dependent diabetes显示文摘 | Serri O | 1991 | JAMA1991，265，20： | 1 |
| 6 | Cabergoline therapy for prolactinomas: is valvular heart disease a real safety concern? 显示文摘 | Vallette S Serri K Serri O | 2010 | Expert review of cardiovascular therapy2010，8，1： | 1 |
| 7 | Frontiers in interventional cardiology 显示文摘 | Topol EJ Serry PW | 1998 | Circulation1998，99，： | 1 |
| 8 | A neural network model of parametric non-linear hysteretic inductors 显示文摘 | CINCOT'I'I S MARCHESI M SERRI A | 1998 | IEEE Transactions on Magnetics1998，34，2： | 1 |
| 9 | Global and regional myocardial function quantification by two-dimensional strain ; application in hypertrophic cardiomyopathy 显示文摘 | Serri K Reant P Lafitte M | 2006 | Am Coll Cardiol2006，47，6： | 1 |
| 10 | Global and regional myocardial function is quantification by twodimensional strain; application in hypertrophic cardiomyopathy 显示文摘 | SERRI K REANT P LAFITrE M | 2006 | Am Coil Cardiol2006，47，6： | 1 |
| 11 | Diagnosis and management of hy- perprolactinemia显示文摘 | Serri O Chick CL Ur E | 2003 | CMAJ2003，169，6： | 1 |
| 12 | Effect of gliclazide on monocyte-endothelium interactions in diabetes显示文摘 | Renier G Desfait s AC Serri O | 2000 | J Diabetes Complications2000，14，4： | 1 |
| 13 | Diagnosis and management of hyperprolactinemia显示文摘 | Omar Serri Constance L Chik | 2003 | CMAJ2003，169，： | 1 |
| 14 | A neural network model of parametric nonlinear hysteretic inductors 显示文摘 | CINCOTTI S MARCHESI M SERRI A | 1998 | Magnetics IEEE Transactions on1998，34，5： | 1 |
| 15 | Diagnosis and management of hyperprolactinemia显示文摘 | Serri O Chik CL Ur E | 2003 | CMAJ2003，169，6： | 1 |
| 16 | Echocar-diographic assessment of cardiac performance in responseto high altitude and development of subclinical pulmona-ry edema in healthy climbers显示文摘 | Maude Page Claude Sauve Karim Serri | 2013 | Ca J Cardiol2013，29，： | 1 |
| 17 | Endovascular Stents: a ‘Break Through Technology', Future Challenges 显示文摘 | Ozaki Y Serrys P W | 1997 | International Journal of Cardiac Imaging1997，13，： | 1 |
| 18 | Cosmeceuticals:focus on topical retinoids in photoaging显示文摘 | Serri R Iorizzo M | 2008 | Clin Dermatol2008，26，6： | 1 |
| 19 | Botulinum toxin type A con-tribution in the treatment of Raynaudf s phenomenon due tosystemic sclerosis显示文摘 | Serri J Legr6 R Veit V | 2011 | Ann Chir Plast Esthet2011，58，6： | 1 |
| 20 | Influence of cusp coverage on the fracture resistance of premolars with endodontic access cavities 显示文摘 | EIAyouti A Serry MI Geis-Gerstorfer J | 2011 | Int Endod J2011，44，6： | 1 |
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