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| 1 | 到用结构化的问询表的口头的抗病毒的肝炎 B 治疗的坚持的评估显示文摘 AIM:To assess adherence rates to nucleos(t)ide analogues(NUCs) therapy in patients with chronic hepatitis B virus infection and determine factors associated with adherence.METHODS:The questionnaire study was conducted in the liver clinics at Concord Repatriation General Hospital.All patients who were currently taking one or more NUCs were asked to complete a structured,selfadministered 32-item questionnaire.Adherence was measured using visual analogue scales.The patient’s treating clinician was also asked to assess their patient’s adherence via a structured questionnaire.RESULTS:A total of 80 patients completed the questionnaire.Sixty six percent of the patients(n = 49) reported optimal adherence whilst 25(33.8%) graded their adherence to NUCs as suboptimal.Thirty four(43%) patients reported to have omitted taking their NUCs sometime in the past.Recent non-adherence was uncommon.Amongst the patients who reported skipping medications,the most common reason cited was 'forgetfulness'(n = 27,56.25%).Other common reasons included:ran out of medications(n = 5,10.42%),being too busy(n = 4,8.33%) and due to a change in daily routine(n = 5,10.42%).Patients who reported low adherence to other prescription pills were also more likely to miss taking NUCs(P = 0.04).Patients who were under the care of a language-discordant clinician were also more likely to report suboptimal adherence to NUCs(P = 0.04).CONCLUSION:Adherence rates were much less than that expected by the physician and has potential adverse affect on long term outcome.Communication and education appear central and strategies need to be implemented to improve ongoing adherence. | Leesa Giang Christian P Selinger Alice Unah Lee | 2012 | World Journal of Hepatology2012，4，2： | 16 |
| 2 | Pregnancy and inflammatory bowel disease: Do we provide enough patient education? A British study of 1324 women显示文摘AIM To examine patient knowledge and factors influencing knowledge about pregnancy in British women with inflammatory bowel disease(IBD).METHODS This is a post hoc analysis of a study of female members of Crohn's and Colitis United Kingdom, aged 18-45 years who were sent an online questionnaire recording patient demographics, education, employment, marital status, and disease characteristics. Disease related pregnancy knowledge was recorded using Crohn's and colitis pregnancy knowledge score(CCPKnow).RESULTS Of 1324 responders, 776(59%) suffered from Crohn's disease, 496(38%) from ulcerative colitis and 52(4%) from IBD-uncategorised. CCPKnow scores were poor(0-7) in 50.8%, adequate(8-10) in 23.6%, good(11-13) in 17.7% and very good(≥ 14) in 7.8%. Multiple linear regression analysis revealed that higher CCPKnow scores were independently associated with higher educational achievement(P < 0.001), younger age at diagnosis(P = 0.003) and having consulted a health care professional about pregnancy and IBD(P = 0.001). CONCLUSION Knowledge was poor in 50%. Speaking with healthcare professionals was a modifiable factor associated with better knowledge. This illustrates the importance of disease related pregnancy | Isabel Carbery Jihane Ghorayeb Anna Madill Christian P Selinger | 2016 | World Journal of Gastroenterology2016，22，36： | 4 |
| 3 | Pregnancy related issues in inflammatory bowel disease: Evidence base and patients' perspective显示文摘Inflammatory bowel disease (IBD) affects women of childbearing age and can influence fertility, pregnancy and decisions regarding breastfeeding. Women with IBD need to consider the possible course of disease during pregnancy, the benefits and risks associated with medications required for disease management during pregnancy and breastfeeding and the effects of mode of delivery on their disease. When indicated, aminosalicylates and thiopurines can be safely used during pregnancy. Infliximab and Adalimumab are considered probably safe during the first two trimesters. During the third trimester the placenta can be crossed and caution should be applied. Methotrexate is associated with severe teratogenicity due to its folate antagonism and is strictly contraindicated. Women with IBD tend to deliver earlier than healthy women, but can have a vaginal delivery in most cases. Caesarean sections are generally recommended for women with active perianal disease or after ileo-anal pouch surgery. While the impact of disease activity and medication has been addressed in several studies, there are minimal studies evaluating patients' perspective on these issues. Women's attitudes may influence their decision to have children and can positively or negatively influence the chance of conceiving, and their beliefs regarding therapies may impact on the course of their disease during pregnancy and/or breastfeeding. This review article outlines the impact of IBD and its treatment on pregnancy, and examines the available data on patients' views on this subject. | Christian P Selinger Rupert WL Leong Simon Lal | 2012 | World Journal of Gastroenterology2012，18，21： | 2 |
| 4 | Inflammatory bowel disease and pregnancy: Lack of knowledge is associated with negative views显示文摘 | Christian P. Selinger Jayne Eaden Warwick Selby D. Brian Jones Peter Katelaris Grace Chapman Charles McDondald John McLaughlin Rupert W.L. Leong Simon Lal | 2012 | Journal of Crohn’s and Colitis2012，，： | 2 |
| 5 | Oxidative modificaton of lipoprotein (a) and the effect of beta - carotene显示文摘 | Naruszewicz M Selinger E Davignon J | 1992 | Metabolism1992，41，： | 1 |
| 6 | Maternal request for caesarean section:an ethical consideration显示文摘 | Selinger H | 2014 | J Med Ethics2014，40，85： | 1 |
| 7 | RNA expression analysis using a 30 base pair resolution Escherichia coli genome array显示文摘 | Selinger D W Cheung K J Mei R | 2000 | Nat Biotechnol2000，18，： | 1 |
| 8 | The rumen-a unique source of enzymes for enhancing livestock production显示文摘 | Selinger L B Forsberg C W Cheng K J | 1996 | Anaerobe1996，2，5： | 1 |
| 9 | Measuring synchronization in neuronal networks for biosensor applications显示文摘 | Selinger JV Pancrazio JJ Gross GW | 2004 | Biosens and Bioelectron2004，19，： | 1 |
| 10 | Plant seed oil-bodies as an immobilization matrix for a recombinant xylanase from the rumen fungus Neocallimastix patriciarum 显示文摘 | Liu J H Selinger L B Cheng K J | 1997 | Moleculor Breeding1997，6，3： | 1 |
| 11 | Substrate assisted catalysis-- application to G proteins显示文摘 | Kosloff M Selinger Z | 2001 | Trends Biochem Sci2001，26，3： | 1 |
| 12 | Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization显示文摘 | Selinger C I Rogers T M Russell P A | 2013 | Mod Pathol2013，26，12： | 1 |
| 13 | Construction planning for linear projects显示文摘 | Selinger S | 1980 | Journal of the Construction Division1980，106，2： | 1 |
| 14 | Limb reduction and ehorionie villus sampling显示文摘 | Oyd PA Keeling JW Selinger M | 1990 | Prenat Diagn1990，10，7： | 1 |
| 15 | Exposure of Norway spruce at the highway border: effects on gas exchange and growth显示文摘 | KAMMERBAUER H ZIEGLER-JOENS A SELINGER H | 1987 | Experientia1987，43，： | 1 |
| 16 | Dis- tribution volumes of ^131I albumin, ^14C sucrose and ^36Cl in sheep显示文摘 | Selinger SL Bland RD Demling RH Staub NC | 1975 | J Appl Physiol1975，39，5： | 1 |
| 17 | Effect of substance P on Rat gastrointestinal transit显示文摘 | P. Silkoff F. Karmeli E. Goldin A. Ewenson C. Gilon M. Chorev R. Laufer Z. Selinger D. Rachmilewitz | 1988 | Digestive Diseases and Sciences1988，，1： | 1 |
| 18 | Oesophageal stent insertion for palliation of dysphagia in a District General Hospital:experience from a case series of 137 patients显示文摘 | Selinger CP Ellul P Smith PA | | 0，，07： | 1 |
| 19 | Determination of remifentanil in human and dog blood by HPLC with UV detection显示文摘 | Selinger K Lanzo C Sekut A | 1994 | J Pharm Biomed Anal1994，12，2： | 1 |
| 20 | Face Recognition with Visible and Thermal Infrared Imagery显示文摘 | Socolinsky D A Selinger A Neuheisel J D | 2003 | Computer vision and image understanding2003，91，12： | 1 |
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