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| 1 | Contrast-enhanced ultrasonography in the evaluation of incidental focal liver lesions: A cost-effectiveness analysis显示文摘AIM To determine whether contrast-enhanced ultrasonography(CEUS) as the first-line method is more costeffective in evaluating incidentally discovered focal liver lesions(FLLs) than is computed tomography(CT) and magnetic resonance imaging(MRI). METHODS Between 2010 and 2015, our prospective study enrolled 459 patients with incidentally found FLLs. The biological nature of FLLs was assessed by CEUS in all patients. CT or MRI examinations were added in unclear cases. The sensitivity and specificity of CEUS were calculated. The total costs of CEUS examinations and of the added examinations performed in inconclusive cases were calculated. Afterwards, the theoretical expenses for evaluating incidentally discovered FLLs using CT or MRI as the first-line method were calculated. The resultswere compared. RESULTS The total cost of the diagnostic process using CEUS for all enrolled patients with FLLs was 75884 USD. When the expenses for additional CT and MRI examinations performed in inconclusive cases were added, the total cost was 90540 US dollar(USD). If all patients had been examined by CT or MR as the first-line method, the costs would have been 78897 USD or 384235 USD, respectively. The difference between the cost of CT and CEUS was 3013 USD(4%) and that between MRI and CEUS was 308352 USD(406.3%). We correctly described 97.06% of benign or malignant lesions, with 96.99% sensitivity and 97.09% specificity. Positive predictive value was 94.16% and negative predictive value was 98.52%. In cases with 4 and more lesions, malignancy is significantly more frequent and inconclusive findings significantly less frequent(P < 0.001).CONCLUSION While the costs of CEUS and CT in evaluating FLLs are comparable, CEUS examination is far more costeffective in comparison to MRI. | Miriama Smajerova Hana Petrasova Jirina Little Petra Ovesna Tomas Andrasina Vlastimil Valek Eva Nemcova Barbora Miklosova | 2016 | World Journal of Gastroenterology2016，22，38： | 4 |
| 2 | 声触诊组织量化技术与超声造影定量分析在肝良恶病灶鉴别诊断中的比较显示文摘目的定量分析肝脏病灶的超声造影(CEUS)参数和声触诊组织量化技术(VTQ)成像特征,对比二者诊断良恶性病灶中的应用价值。方法对79枚肝脏病灶分别进行CEUS和VTQ检查。CEUS动态图像采用QLAB定量软件对病灶绘制时间-强度曲线(TIC),并获取相关的声学定量参数,VTQ检查获得病灶及周围背景肝组织剪切波速度(SWV),比较两种方法在肝脏病灶中的诊断价值。结果肝脏恶性病灶的SWV值明显高于良性病灶,差异具有统计学意义(P<0.01);VTQ和CEUS诊断肝脏良恶性病灶的ROC曲线下面积分别为0.811和0.984,差异具有统计学意义(P<0.05);VTQ对于CEUS诊断不确切的病灶诊断准确度66.67%。结论 CEUS和VTQ在肝良恶性病灶的鉴别诊断中均有较高应用价值,且CEUS诊断价值更高一些,但对于其无法定性的病灶,VTQ有一定的补充诊断价值。 | 舒瑞 赵玉珍 薛薇 何其佳 郝美娜 | 2015 | 中国超声医学杂志2015，31，7： | 2 |
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