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| 1 | Intraductal ultrasound substantiates diagnostics of bile duct strictures of uncertain etiology显示文摘AIM:To report the largest patient cohort study investigating the diagnostic yield of intraductal ultrasound (IDUS) in indeterminate strictures of the common bile duct.METHODS:A patient cohort with bile duct strictures of unknown etiology was examined by IDUS.Sensitivity,specificity and accuracy rates of IDUS were calculated relating to the definite diagnoses proved by histopathology or long-term follow-up in those patients who did not undergo surgery.Analysis of the endosonographic report allowed drawing conclusions with respect to the T and N staging in 147 patients.IDUS staging was compared to the postoperative histopathological staging data allowing calculation of sensitivity,specificity and accuracy rates for T and N stages.The endoscopic retrograde cholangio-pancreatography and IDUS procedures were performed under fluoroscopic guidance using a side-viewing duodenoscope (Olympus TJF 160,Olympus,Ltd.,Tokyo,Japan).All procedures were performed under conscious sedation (propofol combined with pethidine) according to the German guidelines.For IDUS,a 6 F or 8 F ultrasound miniprobe was employed with a radial scanner of 15-20 MHz at the tip of the probe (Aloka Co.,Tokyo,Japan).RESULTS:A total of 397 patients (210 males,187 females,mean age 61.43 ± 13 years) with indeterminate bile duct strictures were included.Two hundred and sixty-four patients were referred to the department of surgery for operative exploration,thus surgical histopathological correlation was available for those patients.Out of 264 patients,174 had malignant disease proven by surgery,in 90 patients benign disease was found.In these patients decision for surgical exploration was made due to suspicion for malignant disease in multimodal diagnostics (computed tomography scan,endoscopic ultrasound or magnetic resonance imaging).Twenty benign bile duct strictures were misclassified by IDUS as malignant while 14 patients with malignant strictures were initially misdiagnosed by IDUS as benign resulting in sensitivity,specificity and accuracy ratesof 93.2%,89.5% and 91.4%,respectively.In the subgroup analysis of malignancy prediction,IDUS showed best performance in cholangiocellular carcinoma as underlying disease (sensitivity rate,97.6%) followed by pancreatic carcinoma (93.8%),gallbladder cancer (88.9%) and ampullary cancer (80.8%).A total of 133 patients were not surgically explored.32 patients had palliative therapy due to extended tumor disease in IDUS and other imaging modalities.Ninety-five patients had benign diagnosis by IDUS,forceps biopsy and radiographic imaging and were followed by a surveillance protocol with a follow-up of at least 12 mo;the mean follow-up was 39.7 mo.Tumor localization within the common bile duct did not have a significant influence on prediction of malignancy by IDUS.The accuracy rate for discriminating early T stage tumors (T1) was 84% while for T2 and T3 malignancies the accuracy rates were 73% and 71%,respectively.Relating to N0 and N1 staging,IDUS procedure achieved accuracy rates of 69% for N0 and N1,respectively.Limitations:Pretest likelihood of 52% may not rule out bias and overinterpretation due to the clinical scenario or other prior performed imaging tests.CONCLUSION:IDUS shows good results for accurate diagnostics of bile duct strictures of uncertain etiology thus allowing for adequate further clinical management. | Tobias Meister Hauke S Heinzow Carina Woestmeyer Philipp Lenz Josef Menzel Torsten Kucharzik Wolfram Domschke Dirk Domagk | 2013 | World Journal of Gastroenterology2013，19，6： | 19 |
| 2 | 应用小波收缩方法剔除MODIS热红外波段数据条带噪声显示文摘采用多元并扫方式 (1km分辨率 1 0元并扫 ,5 0 0m分辨率 2 0元并扫 ,2 5 0m分辨率 4 0元并扫 )的MODIS传感器由于各探测单元在轨响应差异而引起的条带噪声对MODIS定量产品的反演计算精度造成一定影响。这种影响在MODIS的热红外波段尤其明显。为了尽可能减少这种影响 ,提高MODIS定量产品反演精度 ,提出应用小波收缩方法剔除MODIS数据条带噪声。研究首先使用连续小波变换方法分析MODIS条带数据 ,确定MODIS数据条带噪声在小波系数域中的尺度。其次 ,在分析条带噪声模式的基础上 ,使用小波收缩方法对MODIS 1B数据进行噪声剔除计算。最后比较了分别使用噪声剔除前后的两组MODIS 1B数据反演得到的部分云和大气定量遥感产品 ,结果表明 ,使用剔除噪声后的MODIS | 杨忠东 张文建 李俊 W.Paul Menzel Richard A.Frey | 2004 | 遥感学报2004，8，1： | 18 |
| 3 | Comparison of high-resolution ultrasound and MR-enterography in patients with inflammatory bowel disease显示文摘AIM:To compare the results of high-resolution ultrasound(HR-US) and magnetic resonance enterography(MRE) examinations in patients with inflammatory bowel disease(IBD).METHODS:The reports of 250 consecutive cases with known IBD,who had an MRE and HR-US examination,were retrospectively analyzed.Using a patient-based approach we evaluated morphological disease features such as affected bowel wall,stenosis,abscess and fistula.The comparison between the two modalities was based on the hypothesis,that any pathological change described in any imaging modality was a true finding,as no further standard of reference was available for complete assessment.RESULTS:Two hundred and fifty examinations representing 207 different patients were evaluated.Both modalities assessed similar bowel wall changes in 65% of the examinations,with more US findings in 11% and more MRE findings in 15%.When the reports were analyzed with regard to 'bowel wall inflammation',US reported more findings in 2%,while MRE reported more findings in 53%.Stenoses were assessed to be identical in 8%,while US found more in 3% and MRE in 29%(P < 0.01).For abscess detection,US showed more findings in 2%(n = 4) while MRE detected more in 6%(n = 16).US detected more fistulas in 1%(n = 2),while MRE detected more in 13%(n = 32)(P < 0.001).The most common reason for no detected pathology by US was a difficult to assess anatomical region(lesser pelvis,n = 72).CONCLUSION:US can miss clinically relevant pathological changes in patients with IBD mostly due to difficulty in assessing certain anatomical regions. | Andreas G Schreyer Cynthia Menzel Chris Friedrich Florian Poschenrieder Lukas Egger Christian Dornia Gabriela Schill Lena M Dendl Doris Schacherer Christl Girlich Ernst-Michael Jung | 2011 | World Journal of Gastroenterology2011，17，8： | 7 |
| 4 | Towards a Wireless Sensor Platform for Energy Efficient Building Operation显示文摘Currently, the IT-support for energy performance rating of buildings is insufficient. So-called IT-platforms often 'built' of an ad-hoc, inconsistent combination of off-the-shelf building management compo-nents, distributed data metering equipment and several monitoring software tools. A promising approach to achieve consistent, holistic performance data management is the implementation of an integrated, modular wireless sensor platform. This paper presents an approach of how wireless sensors can be seamlessly integrated into existing and future intelligent building management systems supporting improved building performance and diagnostics with an emphasis on energy management. | Karsten Menzel Dirk Pesch Brendan O'Flynn Marcus Keane Cian O'Mathuna | 2008 | Tsinghua Science and Technology2008，13，S1： | 4 |
| 5 | Field-effect passivation on silicon nanowire solar cells显示文摘表面再结合为高效率的太阳能电池代表一个缺陷。这为 nanowire 数组太阳能电池是特别重要的,在 surface-to-volume 比率极大地被提高的地方。这里,有效再结合上并且在设备表演上的不同钝化材料的效果试验性地被分析。我们的太阳能电池是自顶向下的轴的 n-p 连接硅 nanowires 借助于近地的阶段移动平版印刷术(NF-PSL ) 制作了的大区域。我们为最好的房间报导 9.9% 的效率,与 SiO 使钝化 < 潜水艇 class= “ a-plus-plus ” > 2 /SiN x 栈。表面的存在的影响在硅 / 氧化物接口修理了费用密度被学习。 | Anna Dalmau Mallorqui Esther Alarcon-Llado Ignasi Canales Mundet Amirreza Kiani Benedicte Demaurex Stefaan De Wolf Andreas Menzel Margrit Zacharias Anna Fontcuberta i Morra | 2015 | Nano Research2015，8，2： | 3 |
| 6 | Tumors of the papilla of Vater – inadequate diagnostic impact of endoscopic forceps biopsies taken prior to and following sphincterotomy显示文摘 | J. Menzel C. Poremba K.-H. Dietl W. B?cker W. Domschke | 1999 | Annals of Oncology1999，，10： | 3 |
| 7 | Microbial production of 1,3-propanediol显示文摘 | Biebl H Menzel K Zeng A P | | 0，，： | 3 |
| 8 | Role of soluble factors and three-dimensional culture in in vitro differentiation of intestinal macrophages显示文摘AIM: To examine the factor(s) involved in differentiation of intestinal macrophages (IMACs) using a recently established in vitro model. METHODS: To test whether soluble or membrane bound factors induce IMAC-differentiation, freshly elutriated monocytes (MO) were incubated with conditioned media or cell membranes of intestinal epithelial cells (IEC) or cultured with IEC in transwell systems. To determine the importance of an active migration of MO, three- dimensional aggregates from a 1:1-mixture of MO and IEC were examined by immunohistochemistry and flow cytometry. Apoptosis was examined by caspase-3 Western blots. Extracellular matrix production in differentiation models was compared by immunohistochemistry. RESULTS: IMAC differentiation was observed in a complex three-dimensional co-culture model (multicellular spheroid, MCS) with IEC after migration of MO into the spheroids. By co-culture of MO with conditioned media or membrane preparations of IEC no IMAC differentiation was induced. Co-culture of MO with IEC in transwell- cultures, with the two cell populations separated by a membrane also did not result in intestinal-like differentiation of MO. In contrast to IEC-spheroids with immigrating MO in mixed MCS of IEC and MO only a small subpopulation of MO was able to survive the seven day culture period. CONCLUSION: Intestinal-like differentiation of MO in vitro is only induced in the complex three-dimensional MCS model after immigration of MO indicating a roleof cell-matrix and/or cell-cell interactions during the differentiation of IMACs. | Tanja Spoettl Martin Hausmann Katrin Menzel Heidi Piberger Hans Herfarth Juergen Schoelmerich Frauke Bataille Gerhard Rogler | 2007 | World Journal of Gastroenterology2007，13，7： | 3 |
| 9 | Cuticular hydrocarbon profiles differ between ant body parts:implications for communication and our understanding of CHC diffusion显示文摘Insect cuticular hydrocarbons(CHCs)serve as communication signals and protect against desiccation.They form complex blends of up to 150 different compounds.Due to differences in molecular packing,CHC classes differ in melting point.Communication is especially important in social insects like ants,which use CHCs to communicate within the colony and to recognize nestmates.Nestmate recognition models often assume a homogenous colony odor,where CHCs are collected,mixed,and redistributed in the postpharyngeal gland(PPG).Via diffusion,recognition cues should evenly spread over the body surface.Hence,CHC composition should be similar across body parts and in the PPG.To test this,we compared CHC composition among whole-body extracts,PPG,legs,thorax,and gaster,across 17 ant species from 3 genera.Quantitative CHC composition differed between body parts,with consistent patterns across species and CHC classes.Early-melting CHC classes were most abundant in the PPG.In contrast,whole body,gaster,thorax,and legs had increasing proportions of CHC classes with higher melting points.Intraindividual CHC variation was highest for rather solid,late-melting CHC classes,suggesting that CHCs differ in their diffusion rates across the body surface.Our results show that body parts strongly differ in CHC composition,either being rich in rather solid,late-melting,or rather liquid,early-melting CHCs.This implies that recognition cues are not homogenously present across the insect body.However,the unequal diffusion of different CHCs represents a biophysical mechanism that enables caste differences despite continuous CHC exchange among colony members. | Philipp P.SPRENGER Lisa J.GERBES Jacqueline SAHM Florian MENZEL | 2021 | Current Zoology2021，67，5： | 3 |
| 10 | Microbial production of 1,3-propanediol显示文摘 | Biebl H Menzel K Zeng A P | 1999 | Appl Microbiol Biotechnol1999，52，： | 2 |
| 11 | “We Must Grasp the Opportunity that Paris Offers”——Interview with Former President of the European Commission José Manuel Barroso显示文摘THE Fifth Kubuqi International Desert Forum took place last July 28 to 29 in Ordos City in Inner Mongolia.Under the Green Land Partnership Program of the United Nations,and in cooperation with the private sector,China’s government has made remarkable achievements over the last 20 years in fighting desertification in the Kubuqi desert region.During the forum and just five months before the United Nations Climate Change Conference in Paris in December,we spoke with Jose Manuel Bar- | VERENA MENZEL | 2015 | China Today2015，64，5： | 2 |
| 12 | Genetics of the quantitative Lp(a) lipoprotein trait显示文摘 | Gerd Utermann Hans Georg Kraft Hans Jürgen Menzel Thomas Hopferwieser Christoph Seitz | 1988 | Human Genetics1988，，1： | 2 |
| 13 | 龙眼果实商业化采后处理系统的建立(英文)显示文摘基于国际上龙眼果实采后技术的研究结果 ,尤其是中国和泰国的观点 ,建立了龙眼果实采后处理系统 ;介绍了龙眼果实采后处理系统技术如耐贮运品种选择 ,采收成熟度和采收方法 ,选别和分级 ,杀菌剂或熏硫处理 ,检疫杀虫处理 ,预冷 ,包装 ,贮藏 ,运输和销售。 | 林河通 Saichol Ketsa Deirdre M.Holcroft Christopher Menzel 陈绍军 席玙芳 | 2002 | 农业工程学报2002，18，5： | 2 |
| 14 | Dynamics and roles of phragmoplast microfilaments in cell plate formation during cytokinesis of tobacco BY-2 cells显示文摘The phragmoplast is a special apparatus that functions in establishing a cell plate in dividing plant cells. It is known that microfilaments (MFs) are involved in constituting phragmoplast structure, but the dynamic distribution and role of phragmoplast MFs are far from being understood. In this study, the precise structure and dynamics of MFs during the initiation and the late lateral expansion of the phragmoplast were observed by using a tobacco BY-2 cell line stably expressing the microfilament reporter construct GFP-fABD2. Three-dimensional imaging showed that the phragmoplast MFs were initiated by two populations of MFs emerging between the reconstituting daughter nuclei at anaphase, which migrated to the mid-zone and gave rise to two layers of microfilament arrays. FM4-64 stained vesicles accumulated and fused with the cell plate between the two populations of MFs. The two layers of microfilament arrays of phragmoplast with ends overlapped always surrounded the centrifugally expanding cell plate. Partial disruption of MFs at metaphase by low concentration of latrunculin B resulted in the inhibition of the cell plate consolidation and the blockage of cell plate lateral expansion, whereas high concentration of latrunculin B restrained the progression of the cell cycle. Treating the cell after the initiation of phragmoplast led to the cease of the expansion of the cell plate. Our observations provide new insights into the precise structure and dynamics of phragmoplast MFs during cytokinesis and suggest that dynamic phragmoplast MFs are important in cell plate formation. | ZHANG Yan ZHANG WenJie BALUSKA Frantisek MENZEL Diedrik REN HaiYuni | 2009 | Chinese Science Bulletin2009，54，12： | 2 |
| 15 | Messaging App, Social Consultant, Dating Platform–China Succumbs to WeChat Fever显示文摘WHO dares these days to squeeze into the crowd of commuters during rush hour in China’s big cities will certainly come across a new type of mobile phone user.We had already become used to seeing headset-ed and hands-free or Bluetooth-ed folk seemingly soliloquizing in the streets.But recently,more and more people in China are seen holding their smartphones not to their ears,but in a tilted position right | VERENA MENZEL | 2014 | China Today2014，63，1： | 2 |
| 16 | Fundamentals of electron beam testing of integrated circuits显示文摘 | MENZEL E KUBALED E | 1983 | Scanning1983，，5： | 2 |
| 17 | Ultra-wideband bandpass filter with hybrid mierostrip/CPW structure显示文摘 | Wang H Zhu L Menzel W | 2005 | IEEE Microw Wireless Compon Lett2005，15，12： | 1 |
| 18 | Superparamagnetic Iron Oxide Particles: Contrast Media for Magnetic Resonance Imaging显示文摘 | Lawaczeck R Menzel M Pietsch H | 2004 | Appl Organomet Chem2004，，18： | 1 |
| 19 | 18F- Deoxyglucose PET for the staging of oesophageal cancer: influence of histopathological subtype and tumour grading 显示文摘 | Menzel CH Dobert N Rieker O | 2003 | Nuklearmedizin2003，42，3： | 1 |
| 20 | High concentration and productivity of 1,3-propanediol from continuous fermentation of glycerol by Klebsiella pneumoniae显示文摘 | Menzel K Zeng A P Deckwer W D | 1997 | Enzyme Microbiol Techol1997，，20： | 1 |
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