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| 1 | Genome Sequence of Helicobacter pylori hpEurope Strain N6显示文摘 | Wiebke Behrens Tobias B?nig Sebastian Suerbaum Christine Josenhans | 2012 | Journal of Bacteriology2012，，14： | 2 |
| 2 | Medical progress:Helicobacter pylori infection显示文摘 | Suerbaum Sebastian Michetti Pierre | 2002 | N Engl J Med2002，347，15： | 2 |
| 3 | Epidemiology of multi-drug-resistant Gram-negative bacteria: Data from an university hospital over a 36-month period显示文摘 | Ralf-Peter Vonberg Anneke Wolter Iris F. Chaberny Axel Kola Stefan Ziesing Sebastian Suerbaum Petra Gastmeier | 2007 | International Journal of Hygiene and Environmental Health2007，，3： | 1 |
| 4 | Lack of Commensal Flora in Helicobacter pylori –Infected INS-GAS Mice Reduces Gastritis and Delays Intraepithelial Neoplasia显示文摘 | Jennifer L. Lofgren Mark T. Whary Zhongming Ge Sureshkumar Muthupalani Nancy S. Taylor Melissa Mobley Amanda Potter Andrea Varro Daniel Eibach Sebastian Suerbaum Timothy C. Wang James G. Fox | 2011 | Gastroenterology2011，，1： | 1 |
| 5 | Helicobacter pylori : recombination, population structure and human migrations显示文摘 | Sebastian Suerbaum Mark Achtman | 2004 | International Journal of Medical Microbiology2004，，2： | 1 |
| 6 | Genomic evolution and transmission of Helicobacter pylori in two South African families显示文摘 | Xavier Didelot Sandra Nell Ines Yang Sabrina Woltemate Schalk van der Merwe Sebastian Suerbaum | 2013 | Proceedings of the National Academy of Sciences2013，，34： | 1 |
| 7 | Routine bile collection for microbiological analysis during cholangiography and its impact on the management of cholangitis显示文摘 | Ahmed A. Negm Anja Schott Ralf-Peter Vonberg Tobias J. Weismueller Andrea S. Schneider Stefan Kubicka Christian P. Strassburg Michael P. Manns Sebastian Suerbaum Jochen Wedemeyer Tim O. Lankisch | 2010 | Gastrointestinal Endoscopy2010，，2： | 1 |
| 8 | Intraprocedural gastric juice analysis as compared to rapid urease test for real-time detection of Helicobacter pylori显示文摘BACKGROUND Endofaster is an innovative technology that can be combined with upper gastrointestinal endoscopy(UGE)to perform gastric juice analysis and real-time detection of Helicobacter pylori(H.pylori).AIM To assess the diagnostic performance of this technology and its impact on the management of H.pylori in the real-life clinical setting.METHODS Patients undergoing routine UGE were prospectively recruited.Biopsies were taken to assess gastric histology according to the updated Sydney system and for rapid urease test(RUT).Gastric juice sampling and analysis was performed using the Endofaster,and the diagnosis of H.pylori was based on real-time ammonium measurements.Histological detection of H.pylori served as the diagnostic gold standard for comparing Endofaster-based H.pylori diagnosis with RUT-based H.pylori detection.RESULTS A total of 198 patients were prospectively enrolled in an H.pylori diagnostic study by Endofasterbased gastric juice analysis(EGJA)during the UGE.Biopsies for RUT and histological assessment were performed on 161 patients(82 men and 79 women,mean age 54.8±19.2 years).H.pylori infection was detected by histology in 47(29.2%)patients.Overall,the sensitivity,specificity,accuracy,positive predictive value,and negative predictive value(NPV)for H.pylori diagnosis by EGJA were 91.5%,93.0%,92.6%,84.3%,and 96.4%,respectively.In patients on treatment with proton pump inhibitors,diagnostic sensitivity was reduced by 27.3%,while specificity and NPV were unaffected.EGJA and RUT were comparable in diagnostic performance and highly concordant in H.pylori detection(κ-value=0.85).CONCLUSION Endofaster allows for rapid and highly accurate detection of H.pylori during gastroscopy.This may guide taking additional biopsies for antibiotic susceptibility testing during the same procedure and then selecting an individually tailored eradication regimen. | Riccardo Vasapolli Florent Ailloud Sebastian Suerbaum Jens Neumann Nadine Koch Lukas Macke Jörg Schirra Julia Mayerle Peter Malfertheiner Christian Schulz | 2023 | World Journal of Gastroenterology2023，29，10： | 1 |
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