|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 地下水铀污染的原位微生物还原与固定:在美国能源部田纳西橡树岭放射物污染现场的试验显示文摘总结了美国斯坦福大学和橡树岭国家实验室等在美国能源部田纳西州橡树岭综合试验基地进行的铀污染原位微生物修复阶段性试验结果.本试验利用微生物以乙醇为电子供体还原地下水和沉积物中的六价铀为不溶解的四价铀,使之原位固定化.随后通过加入溶解氧和硝酸盐来试验微生物还原后的地下水层中还原固定态铀的稳定性.通过预处理和长期间隔注入乙醇溶液,地下水中铀浓度从40~60mg·L-1降至0.03mg·L-1以下,达到了美国环保署饮用水的标准.还原的四价铀主要以U(Ⅳ)-Fe复合物的形态存在.结果表明,固定化后的四价铀只有在厌氧条件下才是稳定的,溶解氧和硝酸盐侵入地下水层后会使固定化的四价铀重新氧化为溶解态的六价铀.在试验过程中,采用多种分子生物学方法检测了微生物种群的变化和与铀氧化还原反应有关的功能微生物.本研究表明,在维持试验系统无氧和无硝酸盐的条件下,通过添加乙醇为电子供体可有效地促进地下水中土著功能微生物的活性,从而实现铀的原位还原固定与稳定. | 吴唯民 Jack Carley David Watson 顾宝华 Scott Brooks Shelly D.Kelly Kenneth Kemner Joy D.van Nostrand 吴力游 许玫英 周集中 罗剑 Erick Cardenas 黄家琪 Matthew W.Fields Terence L.Marsh James M.Tiedje Stefan J.Green Joel E.Kostka Peter K.Kitanidis Philip M.Jardme CraigS.Criddle | 2011 | 环境科学学报2011，31，3： | 28 |
| 2 | Towards 10 Gb/s orthogonal frequency division multiplexing-based visible light communication using a GaN violet micro-LED显示文摘Visible light communication(VLC)is a promising solution to the increasing demands for wireless connectivity.Gallium nitride micro-sized light emitting diodes(micro-LEDs)are strong candidates for VLC due to their high bandwidths.Segmented violet micro-LEDs are reported in this work with electrical-to-optical bandwidths up to 655 MHz.An orthogonal frequency division multiplexing-based VLC system with adaptive bit and energy loading is demonstrated,and a data transmission rate of 11.95 Gb/s is achieved with a violet micro-LED,when the nonlinear distortion of the micro-LED is the dominant noise source of the VLC system.A record 7.91 Gb/s data transmission rate is reported below the forward error correction threshold using a single pixel of the segmented array when all the noise sources of the VLC system are present. | MOHAMED SUFYAN ISLIM RICARDO X.FERREIRA XIANGYU HE ENYUAN XIE STEFAN VIDEV SHAUN VIOLA SCOTT WATSON NIKOLAOS BAMIEDAKIS RICHARD V.PENTY IAN H.WHITE ANTHONY E.KELLY ERDAN GU HARALD HAAS MARTIN D.DAWSON | 2017 | Photonics Research2017，5，2： | 23 |
| 3 | Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension显示文摘Myeloid cells,such as neutrophils,are produced in the bone marrow in high quantities and are important in the pathogenesis of vascular diseases such as pulmonary hypertension(PH).Although neutrophil recruitment into sites of inflammation has been well studied,the mechanisms of neutrophil egress from the bone marrow are not well understood.Using computational flow cytometry,we observed increased neutrophils in the lungs of patients and mice with PH.Moreover,we found elevated levels of IL-6 in the blood and lungs of patients and mice with PH.We observed that transgenic mice overexpressing Il-6 in the lungs displayed elevated neutrophil egress from the bone marrow and exaggerated neutrophil recruitment to the lungs,resulting in exacerbated pulmonary vascular remodeling,and dysfunctional hemodynamics.Mechanistically,we found that IL-6-induced neutrophil egress from the bone marrow was dependent on interferon regulatory factor 4(IRF-4)-mediated CX3CR1 expression in neutrophils.Consequently,Cx3cr1 genetic deficiency in hematopoietic cells in Il-6-transgenic mice significantly reduced neutrophil egress from bone marrow and decreased neutrophil counts in the lungs,thus ameliorating pulmonary remodeling and hemodynamics.In summary,these findings define a novel mechanism of IL-6-induced neutrophil egress from the bone marrow and reveal a new therapeutic target to curtail neutrophil-mediated inflammation in pulmonary vascular disease. | Jonathan Florentin Jingsi Zhao Yi-Yin Tai Sathish Babu Vasamsetti Scott P.O’Neil Rahul Kumar Anagha Arunkumar Annie Watson John Sembrat Grant C.Bullock Linda Sanders Biruk Kassa Mauricio Rojas Brian B.Graham Stephen Y.Chan Partha Dutta | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 4 | Optimum Lymphadenectomy for Esophageal Cancer显示文摘 | Nabil P. Rizk Hemant Ishwaran Thomas W. Rice Long-Qi Chen Paul H. Schipper Kenneth A. Kesler Simon Law Toni E. M. R. Lerut Carolyn E. Reed Jarmo A. Salo Walter J. Scott Wayne L. Hofstetter Thomas J. Watson Mark S. Allen Valerie W. Rusch Eugene H. Blacksto | 2010 | Annals of Surgery2010，，1： | 2 |
| 5 | The pulsed high-energy radiographic machine emitting X-rays flash radiographic camera显示文摘 | Scott Watson Todd Kauppila Louis Morrison | 1997 | SPIE1997，2869，05： | 1 |
| 6 | Albumin concentrations are primarily determined by the body cell mass and the systemic inflammatory response in cancer patients with weight loss 显示文摘 | McMillan D C Watson W S Scott H R | 2001 | Nutr Cancer2001，39，2： | 1 |
| 7 | Preparation of Nanos-sized Crystalline TiO2 Particles at Low Temperature for Photocatalysis显示文摘 | Watson S Beydoun D Scott J | 2004 | Journal of Nanoparticle Research2004，6，1： | 1 |
| 8 | Real-Time Spot Size Measurement for Pulsed High--energy Radiographic Machines 显示文摘 | Scott A Watson | 1993 | IEEE Particle Acceleration Conference1993，1720，5： | 1 |
| 9 | Preparation of Nanosized Crystalline TiO2 Particles at Low Temperature for Photoeatalysis显示文摘 | Watson S Beydoun D Scott J | 2004 | Journal of Nanoparticle Research2004，6，： | 1 |
| 10 | Phase II Trial of Neoadjuvant/adjuvant Imatinib Mesylate for Advanced Primary and Metastatic/recurrent Operable Gastrointestinal Stromal Tumors: Long-term Follow-up Results of Radiation Therapy Oncology Group 0132显示文摘 | Dian Wang Qiang Zhang Charles Blanke George Demetri Michael Heinrich James Watson John Hoffman Scott Okuno John Kane Margaret Mehren Burton Eisenberg | 2012 | Annals of Surgical Oncology2012，，4： | 1 |
| 11 | The effect of preparation method on the photoactivity of crystalline titanium dioxide particles显示文摘 | S S Watson D Beydoun J A Scott | 2003 | Chemical Engineering Journal2003，95，1： | 1 |
| 12 | EPSPS gene amplification in glyphosate‐resistant Italian ryegrass ( Lolium perenne ssp. multiflorum ) from Arkansas显示文摘 | Reiofeli A Salas Franck E Dayan Zhiqiang Pan Susan B Watson James W Dickson Robert C Scott Nilda R Burgos | 2012 | Pest. Manag. Sci2012，，9： | 1 |
| 13 | Preparation, characterization and scanned conductance microscopy studies of DNA-templated one-dimensional copper nanostructures 显示文摘 | Scott M D Watson Nicholas G W | 2010 | Langmuir2010，26，3： | 1 |
| 14 | A diastereoselective synthe- sis of 2,4-disubstituted piperidines: Scaffolds for drug discovery 显示文摘 | WATSON P S JIANG B SCOTT B | 2000 | Org Lett2000，2，23： | 1 |
| 15 | The effect of preparation method on the photoactivity of crystalline titanium dioxide particles显示文摘 | Watson S S Beydoun D Scott J A | 2003 | Chem Eng J2003，95，： | 1 |
| 16 | Preparation of Nanosized Crystalline TiO2 Particles at Low Temperature for Photocatalysis显示文摘 | Watson S Beydoun D Scott J | 2004 | Journal of Nanoparticle Research2004，6，： | 1 |
| 17 | Prelaminated free radial forearmflap for a total nasal reconstruction显示文摘 | Sinha M Scott J R Watson S B | 2008 | Journal of Plastic Recon-structive & Anesthetic Surgery2008，61，8： | 1 |
| 18 | A comparison between computerized tomography, magnetic resonance imaging, and laser scanning for capturing 3-dimensional data from an object of standard form显示文摘 | Coward TJ Scott BJ Watson RM | 2005 | Int J Prosthodont2005，18，5： | 1 |
| 19 | 糖尿病视网膜病变和黄斑囊样水肿患者曲安奈德眼内注射前、后玻璃体内血管内皮生长因子和基质衍生因子-1的水平显示文摘背景:能导致糖尿病视网膜病变(DR)视力丧失的弥漫性黄斑囊样水肿(DME)和(或)异常新生血管(NV)可能受生长因子和化学激活剂的调节。化学激活素基质衍生因子-1(SDF-1)是一种血管内皮生长因子(VEGF)表达的有效刺激剂,是NV的重要效应物。并且是与发生DME有关血管通透性的关键诱导物。循环中的内皮前体细胞对SDF-1应答迁徙参与NV。目的:调查不同程度的的DR和DME患者。在眼内注射曲安奈德(triamcinolone acetonide)前后,玻璃体中SDF-1和VEGF之间的关系。用于治疗难治的DME。方法:在这一前瞻性的研究中。包括36例患者并观察了6个月。在紧接着注射曲安奈德前和注射1个月后获得的标本,用酶联免疫吸附试验检测玻璃体中VEGF和SDF-1的水平。结果:增生性DR患者的VEGF和SDF-1与非增生DR患者相比显著高(P〈0.01)。DME患者与非DME患者相比较。SDF-1水平显著增加。VEGF与SDF-1的水平和疾病的严重程度相关(r^2=0.88)。结论:应用曲安奈德出现了激动人心的结果,VEGF和SDF-1降到了几乎检测不出来的水平。消除了DME并使活动性的NV退化。我们的结果支持SDF-1和VEGF在DR有害视力后果的发病机制中的作用,并提示注射曲安奈德后,可能由于抑制了VEGF和SDF-1,使得DME消退和(或)NV开始纤维化的退化。 | H. Logan Brooks Sergio Caballero Charles K. Newell Robert L. Steinmetz Debbie Watson Mark S. Segal Jeffrey K. Harrison Edward W. Scott Maria B. Grant 孙文赏(译) 申敏如(校) | 2005 | 美国医学会眼科杂志(中文版)2005，17，2： | 1 |
| 20 | 显示文摘 | Watson S Beydoun D Scott J | 2004 | Journal of Nanoparticle Research2004，6，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员