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| 1 | Cartilage repair techniques of the talus: An update显示文摘Symptomatic chondral or osteochondral defects of the talus reduce the quality of life of many patients.Although their pathomechanism is well understood,it is well known that different aetiologic factors play a role in their origin.Additionally,it is well recognised that the talar articular cartilage strongly differs from that in the knee.Despite this fact,many recommendations for the management of talar cartilage defects are based on approaches that were developed for the knee.Conservative treatment seems to work best in paediatric and adolescent patients with osteochondritis dissecans.However,depending on the size of the lesions,surgical approaches are necessary to treat many of these defects.Bone marrow stimulation techniques may achieve good results in small lesions.Large lesions may be treated by open procedures such as osteochondral autograft transfer or allograft transplantation.Autologous chondrocyte transplantation,as a restorative procedure,is well investigated in the knee and has been applied in the talus with increasing popularity and promising results but the evidence to date is poor.The goals of the current article are to summarise the different options for treating chondral and osteochondral defects of the talus and review the available literature. | Mike H Baums Wolfgang Schultz Tanja Kostuj Hans-Michael Klinger | 2014 | World Journal of Orthopedics2014，5，3： | 11 |
| 2 | Growth of thick chemical solution derived pyrochlore La 2 Zr 2 O 7 buffer layers for YBa 2 Cu 3 O 7? x coated conductors显示文摘 | K. Knoth R. Hühne S. Oswald L. Molina O. Eibl L. Schultz B. Holzapfel | 2007 | Thin Solid Films2007，，8： | 3 |
| 3 | 星形胶质细胞转录组分析指导的脑卒中靶标鉴定显示文摘星形胶质细胞支持正常的脑功能,但在卒中等病理条件下,星形胶质细胞反应性激活,其也可能参与神经退行性改变。反应性星形胶质细胞增生对机体有益或有害,与环境背景有关,但其分子基础仍未得到充分解释。借助RiboTag技术,我们在特异性地短暂性大脑中动脉闭塞(tMCAO)72h后的小鼠星形胶质细胞中,纯化翻译mRNA,构建卒中特异性星形胶质细胞翻译组数据库。我们发现,与对照组脑组织相比,tMCAO后的反应性星形胶质细胞显示与A2表型相关的转录物的富集,这与神经保护相关。星形胶质细胞也会上调大量潜在的神经毒性基因。我们共鉴定了1003个基因和38个转录因子的差异表达,其中Stat3,Sp1和Spi1变化最明显。为了进一步探索Stat3介导的通路对卒中发病机制的影响,我们选择星形胶质细胞特异性条件性缺失Stat3的小鼠制造tMCAO模型,发现这些小鼠的局灶性缺血卒中体积减少,且梗死72h后小鼠的运动结果改善。综上所述,本研究扩展了新兴的星形胶质细胞特异性靶向卒中治疗数据库,并肯定了星形胶质细胞是脑功能的关键保障细胞。 | Rakers C Schleif M Blank N Matu?ková H Ulas T H?ndler K Torres SV Schumacher T Tai K Schultze JL Jackson WS Petzold GC 聂昊 | 2019 | 神经损伤与功能重建2019，14，6： | 2 |
| 4 | Isolation ofvolatile components from a model system显示文摘 | Schultz T H Flath R A Richard Mon T | 1977 | J Agric FoodChem1977，25，3： | 1 |
| 5 | Point muta- tions in the S protein connect the sialic acid binding activity with the enteropathogenicity of transmissible gastroenteritis coronavirus 显示文摘 | Krempl C Schultze B Laude H Herrler G | 1997 | J Virol1997，71，4： | 1 |
| 6 | Gmres: a generalized mini- mal residual algorithm for solving nonsymmetric linear systems显示文摘 | SAAD Y SCHULTZ M H | 1986 | SIAM Journal on Scientific and Statisti- cal Computing1986，7，： | 1 |
| 7 | High temperature magnetic properties of 2:17 Sin-Co magnets 显示文摘 | SCHOBINGER D GUTFEISCH O HINZ D MULLER K H SCHULTZ L MARTINEK G | 2002 | Journal of Magnetism and Magnetic Materials2002，，： | 1 |
| 8 | Import of mitochondrial transcription factor A (TFAM) into rat liver mitochondria stimulates transcription of mitochondrial DNA 显示文摘 | GARSTKA H L SCHMITT W E SCHULTZ J | 2003 | Nucleic Acids Res2003，31，17： | 1 |
| 9 | Thiochromanones and transformation products显示文摘 | KROLLPFEIFFER F SCHULTZE H | 1923 | Ber1923，56，： | 1 |
| 10 | Integrative genomic profi- ling of human prostate cancer 显示文摘 | Taylor BS Schultz N Hieronymus H | 2010 | Cancer Cell2010，18，1： | 1 |
| 11 | Laboratory investigations of impact-generated plasma显示文摘 | Crawford A Schultz P H | 1991 | JournalGeophysics Research1991，96，18： | 1 |
| 12 | GMRES:a generalized minimal residual algorithm for solving nonsymmetric linear systems显示文摘 | SAAD Y SCHULTZ H | 1986 | SIAM J Sci Statist Comput1986，7，3： | 1 |
| 13 | Effect of impact angle on vaporization显示文摘 | Schultz P H | 1996 | J Geophys Res1996，101，21： | 1 |
| 14 | The bactericidal/permeability-increasing protein (BPI) : a target antigen of autoantibodies显示文摘 | SCHULTZ H WEISS J CARROLL S F | 2001 | J Leukoc Biol2001，69，3： | 1 |
| 15 | Electromagnetic properties of impact generated plasma,vapor and debris显示文摘 | David A Crawford A Schultz P H | 1999 | International Journal of Impact Engineering1999，23，： | 1 |
| 16 | Sample size and retention values in high-performance liquid chromatography of biological and synthetic polymers显示文摘 | Czok M Schultz R | 1988 | J Chromatogr1988，458，： | 1 |
| 17 | State of the Art Light Triggered Thyristor with Integrated Protection Functions 显示文摘 | Kellner U Niedernostheide F J Schultze H J | 2002 | Power Electronics Europe2002，，2： | 1 |
| 18 | GMRES:a generalized minimal residual algorithm for solving nonsymmetric linear systems显示文摘 | Saad Y Schultz M H | 1986 | Comput Appl Math1986，7，： | 1 |
| 19 | Relay based deployment concepts for wireless and mobilebroadband radio 显示文摘 | Pabst R Walke B H Schultz D C | 2004 | IEEE Communications Maga- zine2004，42，9： | 1 |
| 20 | Vaccination of cancer patients against telomerase induces funetinnal antitumor CD8 + T lymphocytes 显示文摘 | Vnnderheide R H Dnmehek S M Schultze J l | 2004 | Clin Cancer Res2004，10，3： | 1 |
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