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| 1 | In vivo imaging of endogenous neural stem cells in the adult brain显示文摘The discovery of endogenous neural stem cells(e NSCs) in the adult mammalian brain with their ability to self-renew and differentiate into functional neurons, astrocytes and oligodendrocytes has raised the hope for novel therapies of neurological diseases. Experimentally, those e NSCs can be mobilized in vivo, enhancing regeneration and accelerating functional recovery after, e.g., focal cerebral ischemia, thus constituting a most promising approach in stem cell research. In order to translate those current experimental approaches into a clinical setting in the future, non-invasive imaging methods are required to monitor e NSC activation in a longitudinal and intraindividual manner. As yet, imaging protocols to assess eNSC mobilization non-invasively in the live brain remain scarce, but considerable progress has been made in this field in recent years. This review summarizes and discusses the current imaging modalities suitable to monitor e NSCs in individual experimental animals over time, including optical imaging, magnetic resonance tomography and-spectroscopy, as well as positron emission tomography(PET). Special emphasis is put on the potential of each imaging method for a possible clinical translation, and on the specificity of the signal obtained. PET-imaging with the radiotracer 3'-deoxy-3'-[18F]fluoro-L-thymidine in particular constitutes a modality with excellent potential for clinical translation but low specificity; however, concomitant imaging of neuroinflammation is feasible and increases its specificity. The non-invasive imaging strategies presented here allow for the exploitation of novel treatment strategies based upon the regenerative potential of e NSCs, and will help to facilitate a translation into the clinical setting. | Maria Adele Rueger Michael Schroeter | 2015 | World Journal of Stem Cells2015，7，1： | 3 |
| 2 | Expression of Tissue Factor in High-Grade Carotid Artery Stenosis: Association With Plaque Destabilization显示文摘 | Sebastian Jander Matthias Sitzer Angélique Wendt Michael Schroeter Martin Buchkremer Mario Siebler Wolfram Müller Wilhelm Sandmann Guido Stoll | 2001 | Stroke: Journal of the American Heart Association2001，，4： | 3 |
| 3 | Antibiotic Resistance in Salmonella Isolates from Imported Chicken Carcasses in Bhutan and from Pig Carcasses in Vietnam显示文摘 | Ellerbroek L Narapati D Tai N Phu Poosaran N Pinthong R Sirimalaisuwan A Tshering P Fries R Zessin K-h Baumann M Schroeter A | 2010 | Journal of Food Protection2010，，2： | 2 |
| 4 | Anassessment of the relationship between chlorophyll fluorescence and CO2 gas exchange from field measurement on a moss and lichen 显示文摘 | GREEN T G A SCHROETER B KAPPEN L | 1998 | Planta1998，206，4： | 2 |
| 5 | Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts显示文摘 | SPENCER J P SCHROETER H CROSSTHWAITHE A J | 2001 | Free Radic Biol Med2001，31，9： | 1 |
| 6 | Central nervous system inflammatory response after cerebral infarction as detected by magnetic resonance imaging 显示文摘 | Saleh A Wiedermann D Schroeter M | 2004 | NMR in biomedicine2004，17，4： | 1 |
| 7 | Analysis of blind-holes applied in the hole-drilling method for residual stress measurements 显示文摘 | BLODORN R VIOTTI M R SCHROETER R B | 2015 | Experimental Mechanics A2015，55，9： | 1 |
| 8 | Flavonoids protect neurons from oxidized low-density-lipoprotein- induced apoptosis involving c-Jun N-terminal kinase (JNK), c- Jun and caspase-3显示文摘 | SCHROETER H SPEMCER JP RICE-EVANS C | 2001 | Biochem J2001，358，3： | 1 |
| 9 | Hierarchical image segmentation by multidimensional clustering and orientation-adaptive boundary refinement 显示文摘 | Schroeter P Bigun J | 1995 | Pattern Recognition1995，28，5： | 1 |
| 10 | Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain显示文摘 | Jander S Schroeter M Peters O | 2001 | J Cereb Blood Flow Metab2001，21，3： | 1 |
| 11 | Evaporation control of monomers from solventless resin composltions显示文摘 | Schroeter S H Bolon D A Webb K K | 1977 | Radiation Physics and Chemistry1977，14，36： | 1 |
| 12 | Non-invasive induction of focal cerebral ischemia in mice by photothrombosis of cortical microvessels: characterization of inflammatory responses 显示文摘 | Schroeter M Jander S Stoll G | 2002 | J Neurosci Methods2002，117，1： | 1 |
| 13 | Astroglial responses in photochemically induced focal ischemia of the rat cortex显示文摘 | Schroeter M Schiene K Kraemer K | 1995 | Exp Brain Res1995，106，1： | 1 |
| 14 | Persistence and transport of bacteria and viruses in groundwater-a conceptual evaluation 显示文摘 | Matthess G Pekdeger A Schroeter J | 1955 | Journal of Contaminant Hydrology1955，2，2： | 1 |
| 15 | Effective treatment of rosacea using intense pulsed light systems 显示文摘 | Schroeter CA Haaf-von Below S Neumann HA | 2005 | Dermatol Surg2005，31，10： | 1 |
| 16 | Rho-kinase inhibitors as therapeutics:from pan inhibition to isoform selectivity显示文摘 | Hahmann C Schroeter T | | 0，，02： | 1 |
| 17 | Reprogramming of the ERR c and ERa target gene landscapetriggers tamoxifen resistance in breast cancer显示文摘 | Thewes V Simon R Schroeter P | 2015 | Cancer Res2015，75，4： | 1 |
| 18 | Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3 显示文摘 | SCHROETER H SPENCER JPE RICE-EVANS C | 2001 | Biochem J2001，358，3： | 1 |
| 19 | Shape - memory polymer networks from oligo ( ε- caprolactone ) dimethacrylates 显示文摘 | Lendlein A Schmidt A Schroeter M | 2005 | Journal of Polymer Science: Part A: Polymer Chemistry2005，43，： | 1 |
| 20 | Gene probe analysis of soil microbial populations selected by amendment with 2,4-dichlorophenoxyacetic acid显示文摘 | Holben W E Schroeter B M Calabrese G M | 1992 | Appl Environ Microbiol1992，58，： | 1 |
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