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26篇 您的检索式:作者名="Schofield AC"
    题名 作者 年代 出处 被引量
1Can patients'likelihood of benefiting from primary chemotherapy for breast cancer be predicted before commencement of treatment显示文摘Ogston KN Miller ID Schofield AC 2004Breast Cancer Research&Treatment2004,86,2:1
2miRNA-34a is associated with docetaxel resistance in human breast cancer cells显示文摘Kastl L Brown I Schofield AC 2012Breast Cancer Res Treat2012,131,2:1
3Changes in human hepatic metabolism in steatosis and cirrhosis显示文摘AIM To understand the underlying metabolic changes in human liver disease we have applied nuclear magnetic resonance(NMR) metabolomics analysis to human liver tissue.METHODS We have carried out pilot study using 1H-NMR to derive metabolomic signatures from human liver from patients with steatosis, nonalcoholic steatohepatitis(NASH) or alcohol-related liver damage(ARLD) to identify species that can predict outcome and discriminate between alcohol and metabolic-induced liver injuries. RESULTS Changes in branched chain amino acid homeostasis, tricarboxylic acid cycle and purine biosynthesis intermediates along with betaine were associated with the development of cirrhosis in both ARLD and nonalcoholic fatty liver disease. Species such as propylene glycol and as yet unidentified moieties that allowed discrimination between NASH and ARLD samples were also detected using our approach.CONCLUSION Our high throughput, non-destructive technique for multiple analyte quantification in human liver specimens has potential for identification of biomarkers with prognostic and diagnostic significance.Zoe Schofield Michelle AC Reed Philip N Newsome David H Adams Ulrich L Günther Patricia F Lalor 2017World Journal of Gastroenterology2017,23,15:1
4Nutrition and the surgical patient:triumphs and challenges显示文摘Heys SD Schofield AC Wahle KW 0,,:1
51018 Trichostatin A and decitabine reverses resistance to docetaxel in human breast cancer cells显示文摘Kastl L Brown I Schofield AC 2009Eur J Cancer Suppl2009,7,2:1
6Nutrition and the surgical patient:triumphs and challenges显示文摘Heys SD Schofield AC Wahle KW 2005Surgeon2005,3,3:1
7Docosahexaenoic acid enhances the efficacy of docetaxel in prostate cancer cells by modulation of apoptosis:The role of genes associated with the NF‐κB pathway显示文摘Shaikh IAA Brown I Schofield AC 2008The Prostate2008,68,15:1
8miRNA-34a is associated with docetaxel resistance in human breast Cancer cells显示文摘Kastl L Brown I Schofield AC 2012Breast Cancer Res Treat2012,131,2:1
9MiRNA-34a is associated with docetaxel resistance in human breast cancer cells 显示文摘Kastl L Brown I Schofield AC 2012Breast Cancer Res Treat2012,131,2:1
10Can patients' likelihood of benefiting from primary chemotherapy for breast cancer be predicted before commencement of treatment显示文摘Ogston KN Miller ID Schofield AC 2004Breast Cancer Res Treat2004,86,2:1
11Can patients likelihood of benefiting from primary chemotherapy for breast cancer be predicted before commencement of treatment显示文摘Ogston KN Miller ID Schofield AC 2004Breast Cancer Res Treat2004,86,:1
12miRNA-34a is associated with docetaxel resistance in human breast cancer cells显示文摘Kastl L Brown I Schofield AC 2012Breast Cancer Res Treat2012,131,2:1
13Effects of decitabine on the expression of selected endogenous control genes in human breast cancer cells显示文摘KASTL L BROWN I SCHOFIELD AC 2010Mol Cell Probe2010,24,2:1
14Folate and breast cancer:the role of polymorphisms in methylenetetrahydrofolate reductase (MTHFR)显示文摘Sharp L Little J Schofield AC 2002Cancer Letter2002,181,1:1
15miRNA-34a is associated with docetaxel resistance in human breast cancer cells显示文摘Kastl L Brown I Schofield AC 2012Breast Cancer Res Treat2012,131,2:1
16Can patients likelihood of benefiting from primary chemotherapy for breast ancer be predicted before commencement of treatment显示文摘Ogston KN Miller ID Schofield AC 2004Breast Vancer Res Treat2004,86,:1
17miRNA-34a is associated with docetaxel resistance in human breast cancer cells显示文摘Kastl L Brown I Schofield AC 2012Breast Cancer Res Treat2012,131,2:1
18miRNA-34a is associated with docetaxel resistance in human breast cancer cells显示文摘Kastl L Brown I Schofield AC 2012Breast Cancer Res Treat2012,131,2:1
19miRNA-34a is associat- ed with docetaxel resistance in human breast cancer cells 显示文摘Kastl L Brown I Schofield AC 2012Breast cancer research and treatment2012,131,2:1
20miRNA-34a is associated with docetaxel resistance in human breast cancer cells显示文摘L Kastl I Brown AC Schofield 2012Breast Cancer Res Treat2012,131,:1
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