|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | FK866, a highly specific noncompetitive inhibitor of nicotinamide phospho ribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis 显示文摘 | Hasmann M I Schemainda | 2003 | Cancer Res2003，63，21： | 1 |
| 2 | Metabolism of Carotenoid Degradation in leaves of Camellia sinensis-Functional and biochemical modifications显示文摘 | Felfe C Schemainda M Baldermann S Watanabe N Fleischmann P | | 0，，06： | 1 |
| 3 | FK866,a highly specific noncompeti-tive inhibitor of nicotinamide phosphoribosyltransferase,representsa novel mechanismfor induction of tumor cell apoptosis显示文摘 | Hasmann M Schemainda I | 2003 | Canc-er Res2003，63，21： | 1 |
| 4 | Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents显示文摘 | Pogrebniak A Schemainda I Azzam K | 2006 | Eur J Med Res2006，11，8： | 1 |
| 5 | FK866, a highly specific noncompeti - tive inhibitor of nicotinamide phosphoribosyltransferase, represent- sa novel mechanism for induction of tumor cell apoptosis 显示文摘 | Hasmann M Schemainda I | 2003 | Cancer Res2003，63，21： | 1 |
| 6 | FK866,a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase,represents a novel mechanism for induction of tumor cell apoptosis显示文摘 | Hasmann M Schemainda I | 2003 | Cancer Res2003，63，21： | 1 |
| 7 | Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combi- nation with antineoplastic agents 显示文摘 | Pogrebniak A Schemainda I Azzam K | 2006 | Eur J Med Res2006，11，8： | 1 |
| 8 | FK866, a highly specific noncom- petitive inhibitor of nicotinamide phosphoribosyltransferase, re- presents a novel mechanism for induction of tumor cell apopto- sis显示文摘 | Hasmann M Schemainda I | 2003 | Cancer Res2003，63，： | 1 |
| 9 | FK866,a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase,represents a novel mechanism for induction of tumor cell apoptosis显示文摘 | Hasmann M Schemainda I | 2003 | Cancer Res2003，63，21： | 1 |
| 10 | FK866, a highly specific noncompeti- tive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis 显示文摘 | Hasmann M Schemainda I | 2003 | Cancer Res2003，63，21： | 1 |
| 11 | FK866,a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyl transferase,represents a novel mechanism for induction of tumor cell apoptosis显示文摘 | Hasmann M Schemainda I | 2003 | Cancer Res2003，63，21： | 1 |
| 12 | Morphology of the middle rectal arteries显示文摘 | Professor LjA DiDio C. Diaz-Franco R Schemainda AJC Bezerra | 1986 | Surgical and Radiologic Anatomy1986，，4： | 1 |
| 13 | Multiple Seasonal Modifications in Enzymatic Flavour Formation in Tea显示文摘Carotenoid cleavage enzymes isolated from Japanese Camellia sinensis leaves(cultivar Yabukita) were used for investigating the structural patterns of carotenoid cleavage enzymes.Fresh tea leaves were used for the isolation of active enzymes and purified to single band stage in SDS PAGE gels after isoelectric focusing.The specific activity of the carotenoid cleavage enzymes was tested and the active fractions selected for further analysis.The sugar content and the amount of phosphate present in the purified enzymes were elucidated by the following methods:Phosphates were detected by phosphatase assays,fluorescence marker kits and ammoniumheptamolybdate complex measurements after incineration of the samples.Sugars were detected in gels using PAS reagent(periodide acid /Schiff reagent) staining and by GC-MS after hydrolysation of the proteins with trifluoric acid.Phosphorylations as well as glycosylations of the samples could be detected in all cases,thus giving evidence for an increasing phosphorylation level of proteins in Camellia sinensis from spring(1.84 g/mg) to autumn(2.39 g/mg) as well as the presence of at least four different sugars(arabinose,xylose,galactose and ribose).These secondary modifications of the carotenoid cleavage enzymes and their dependency on the harvesting season may well correspond to the changes on the functional level which were detected between spring(Michaelis Constant(K m) =9.45 mol/l) and autumn(K m= 17.16 mol/l) harvests. | Christiane Felfe Matthias Schemainda Susanne Baldermann Naoharu Watanabe Peter Fleischmann | 2013 | 茶叶2013，39，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员