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| 1 | Impact of gout on in-hospital outcomes of acute coronary syndrome-related hospitalizations and revascularizations: Insights from the national inpatient sample显示文摘BACKGROUND Previous studies have established a role of gout in predicting risk and prognosis of cardiovascular diseases. However, large-scale data on the impact of gout on inpatient outcomes of acute coronary syndrome (ACS)-related hospitalizations and post-revascularization is inadequate. AIM To evaluate the impact of gout on in-hospital outcomes of ACS hospitalizations, subsequent healthcare burden and predictors of post-revascularization inpatient mortality. METHODS We used the national inpatient sample (2010-2014) to identify the ACS and goutrelated hospitalizations, relevant comorbidities, revascularization and postrevascularization outcomes using the ICD-9 CM codes. A multivariable analysis was performed to evaluate the predictors of post-revascularization in-hospital mortality. RESULTS We identified 3144744 ACS-related hospitalizations, of which 105198 (3.35%) also had gout. The ACS-gout cohort were more often older white males with a higher prevalence of comorbidities. Coronary artery bypass grafting was required more often in the ACS-gout cohort. Post-revascularization complications including cardiac (3.2% vs 2.9%), respiratory (3.5% vs 2.9%), and hemorrhage (3.1% vs 2.7%) were higher whereas all-cause mortality was lower (2.2% vs 3.0%) in the ACSgout cohort (P < 0.001). An older age (OR 15.63, CI: 5.51-44.39), non-elective admissions (OR 2.00, CI: 1.44-2.79), lower household income (OR 1.44, CI: 1.17- 1.78), and comorbid conditions predicted higher mortality in ACS-gout cohort undergoing revascularization (P < 0.001). Odds of post-revascularization inhospital mortality were lower in Hispanics (OR 0.45, CI: 0.31-0.67) and Asians (OR 0.65, CI: 0.45-0.94) as compared to white (P < 0.001). However, postoperative complications significantly raised mortality odds. Mean length of stay, transfer to other facilities, and hospital charges were higher in the ACS-gout cohort. CONCLUSION Although gout was not independently associated with an increased risk of postrevascularization in-hospital mortality in ACS, it did increase postrevascularization complications. | Rupak Desai Tarang Parekh Hemant Goyal Hee Kong Fong Dipen Zalavadia Nanush Damarlapally Rajkumar Doshi Sejal Savani Gautam Kumar Rajesh Sachdeva | 2019 | World Journal of Cardiology2019，11，5： | 4 |
| 2 | Reconstitution of FOXP3 + regulatory T cells (Tregs) after CD25-deple?ted allo-transplantation in elderly patients and association with acute graft-versus-host disease显示文摘 | Mielke S Rezvani K Savani B N | 2007 | Blood2007，110，5： | 1 |
| 3 | Factors associated with early molecular remission after T cell-depleted allogeneic stem cell transplantation for chronic myeogenous leukemia 显示文摘 | Savani BN Rezvani K Mielke S | 2006 | Blood2006，107，4： | 1 |
| 4 | Peripheral Blood Progeni-tor Cell Mobilization for Autologous and Allogeneic HematopoieticCell Transplantation : Guidelines from the American Society forBlood and Marrow Transplantation 显示文摘 | Duong HK Savani BN Copelan E | 2014 | Biol Blood Marrow Trana-plant2014，20，9： | 1 |
| 5 | Abdominal metastases from lung cancer resulting in small bowel perforation: report of three cases 显示文摘 | Savanis G Simatos G Lekka I | 2006 | Tumori2006，92，2： | 1 |
| 6 | Respiratory distress after intratracheal bleomycin:selective deficiency of surfactant proteins B and C显示文摘 | SAVANI RC GODINEZ RI GODINEZ MH | 2001 | Am J Physiol Lung Cell Mol Physiol2001，281，3： | 1 |
| 7 | American journal of physiology 显示文摘 | Strayer M Savani BC Gonzales LW et aL Human surfac- tant protein B promoter in transgenic mice: temporal spa- tial and stimulus-responsive regulation | 2002 | Lung Cell Mol Physiol2002，282，： | 1 |
| 8 | Toll-like receptors, the NL- RP3 inflammasome, and interleukin-113 in the development and progression of type 1 diabetes 显示文摘 | Grishman EK White PC Savani RC | 2012 | Pediatr Res2012，，71： | 1 |
| 9 | Efficacy and tolerability of naratriptan for short-term prevention of menstrually related migraine:data from two randomized,double-blind,placebo-controlled studies显示文摘 | Mannix LK Savani N Landy S | 2007 | Headache2007，47，： | 1 |
| 10 | Bleomycin-induced pulmonary injury in mice deficient in SPARC显示文摘 | SAVANI R C ZHOU Z ARGUIRI E | | 0，，04： | 1 |
| 11 | Cannabidiol in vivo blunts bamyloid induced neuroinflammation by suppressing IL-lb and iNOS expression显示文摘 | Esposito G Scuderi C Savani C | 2007 | Br J Pharmacol2007，151，： | 1 |
| 12 | A new tension-free technique for the repair of umbilical hernia, using the Prolene Hernia System — early results from 48 cases显示文摘 | E. Perrakis G. Velimezis A. Vezakis J. Antoniades G. Savanis V. Patrikakos | 2003 | Hernia2003，，4： | 1 |
| 13 | Recombinant factor VlIa to treat diffuse alveolar hemorrhage following allogeneic stem cell transplantation显示文摘 | Shenoy A Savani BN Barrett AJ | 2007 | Biol Blood Marrow Transplant2007，13，5： | 1 |
| 14 | Recombinant factor VIIa to treat diffuse alveolar hemorrhage following allogeneic stem cell transplantation显示文摘 | Shenoy A Savani BN Barrett AJ | 2007 | Biol Blood Marrow Transplant2007，13，5： | 1 |
| 15 | Differential involvement of the hyaluronan(HA)receptors CD44 and receptor for HA-mediated motility in endothelial cell function and angmgenesls显示文摘 | Savani RC Cao G Pooler PM | | 0，，39： | 1 |
| 16 | The first record in the Americas of an autochthonous case of Leishmania ( Leishmania ) infantum chagasi in a domestic cat ( Felix catus ) from Cotia County, S?o Paulo State, Brazil显示文摘 | Elisa San Martin Mouriz Savani Maria Cec??lia Gibrail de Oliveira Camargo Mar??lia Russi de Carvalho Ricardo Andrade Zampieri Marcos Gonzaga dos Santos Sandra Regina Nicoletti D’áuria Jeffrey J Shaw Lucile Maria Floeter-Winter | 2004 | Veterinary Parasitology2004，，3： | 1 |
| 17 | Serum hyaluronan and its association with unfavorable histology and aggressiveness of heterotransplanted Wilms'tumor显示文摘 | Lovvorn HN Savani RC Ruchelli E | | 0，，07： | 1 |
| 18 | Opposing control of cannabinoid re- ceptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence显示文摘 | Esposito G Iuvone T Savani C Scuderi C De Filippis D Papa M | 2007 | J Pharmacol Exp Ther2007，322，3： | 1 |
| 19 | Impact of conditioning intensity in T- replete haplo- identical stem cell transplantation for acute leukemia:a report from the acute leukemia working party of the EBMT显示文摘 | Rubio MT Savani BN Labopin M | 2016 | J Hematol Oncol2016，9，： | 1 |
| 20 | Modulation of monocyte-endothelial cell interactions by platelet microparticles显示文摘 | Barry OP Pratico D Savani RC | | 0，，： | 1 |
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